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Items: 1 to 20 of 25

1.
Identification and Characterization of Novel Fusion Genes with Potential Clinical Applications in Mexican Children with Acute Lymphoblastic Leukemia
Minerva Mata-Rocha, Angelica Rangel-López, Elva Jiménez-Hernández, Blanca Angélica Morales-Castillo, Carolina González-Torres, Javier Gaytan-Cervantes, Enrique Álvarez-Olmos, Juan Carlos Núñez-Enríquez, Arturo Fajardo-Gutiérrez, Jorge Alfonso Martín-Trejo, Karina Anastacia Solís-Labastida, Aurora Medina-Sansón, Janet Flores-Lujano, Omar Alejandro Sepúlveda-Robles, José Gabriel Peñaloza-González, Laura Eugenia Espinoza-Hernández, Nora Nancy Núñez-Villegas, Rosa Martha Espinosa-Elizondo, Beatriz Cortés-Herrera, José Refugio Torres-Nava, Luz Victoria Flores-Villegas, Laura Elizabeth Merino-Pasaye, Vilma Carolina Bekker-Méndez, Martha Margarita Velázquez-Aviña, María Luisa Pérez-Saldívar, Benito Alejandro Bautista-Martínez, Raquel Amador-Sánchez, Ana Itamar González-Avila, Silvia Jiménez-Morales, David Aldebarán Duarte-Rodríguez, Jessica Denisse Santillán-Juárez, Alejandra Jimena García-Velázquez, Haydeé Rosas-Vargas, Juan Manuel Mejía-Aranguré
Int J Mol Sci. 2019 May; 20(10): 2394. Published online 2019 May 15. doi: 10.3390/ijms20102394
PMCID:
PMC6566803
AbstractArticlePDF–1.7M
2.
Genome wide mapping of ETV6 binding sites in pre-B leukemic cells
Benjamin Neveu, Maxime Caron, Karine Lagacé, Chantal Richer, Daniel Sinnett
Sci Rep. 2018; 8: 15526. Published online 2018 Oct 19. doi: 10.1038/s41598-018-33947-1
PMCID:
PMC6195514
AbstractArticlePDF–2.4M
3.
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.
T R Golub, G F Barker, S K Bohlander, S W Hiebert, D C Ward, P Bray-Ward, E Morgan, S C Raimondi, J D Rowley, D G Gilliland
Proc Natl Acad Sci U S A. 1995 May 23; 92(11): 4917–4921. doi: 10.1073/pnas.92.11.4917
PMCID:
PMC41818
SummaryPage BrowsePDF–1.3M
4.
Genetic variants and clinical significance of pediatric acute lymphoblastic leukemia
Hong-Hong Zhang, Hong-Sheng Wang, Xiao-Wen Qian, Cui-Qing Fan, Jun Li, Hui Miao, Xiao-Hua Zhu, Yi Yu, Jian-Hua Meng, Ping Cao, Jun Le, Jun-Ye Jiang, Wen-Jing Jiang, Ping Wang, Xiao-Wen Zhai
Ann Transl Med. 2019 Jul; 7(14): 296. doi: 10.21037/atm.2019.04.80
PMCID:
PMC6694231
AbstractArticlePDF–1.1M
5.
Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma
David S. Ziegler, Marie Wong, Chelsea Mayoh, Amit Kumar, Maria Tsoli, Emily Mould, Vanessa Tyrrell, Dong-Anh Khuong-Quang, Mark Pinese, Velimir Gayevskiy, Richard J. Cohn, Loretta M. S. Lau, Mark Reynolds, Michael C. Cox, Andrew Gifford, Michael Rodriguez, Mark J. Cowley, Paul G. Ekert, Glenn M. Marshall, Michelle Haber
Br J Cancer. 2018 Sep 11; 119(6): 693–696. Published online 2018 Sep 17. doi: 10.1038/s41416-018-0251-2
PMCID:
PMC6173734
AbstractArticlePDF–1.3M
6.
Successful Targeted Therapy of Refractory Pediatric ETV6-NTRK3 Fusion-Positive Secretory Breast Carcinoma
Neerav Shukla, Stephen S. Roberts, Mollah O. Baki, Qazi Mushtaq, Paul E. Goss, Ben H. Park, Gunes Gundem, Ken Tian, Heather Geiger, Kristie Redfield, Gerald Behr, Ryma Benayed, Ahmet Zehir, Jaclyn F. Hechtman, Robert B. Darnell, Elli Papaemmanuil, Marc Ladanyi, Nora Ku, Andrew L. Kung, José Baselga, Alexander Drilon, David M. Hyman
JCO Precis Oncol. 2017; 1: PO.17.00034. Published online 2017 Aug 15. doi: 10.1200/PO.17.00034
PMCID:
PMC5880290
ArticlePDF–1.3M
7.
High-resolution detection of chromosomal rearrangements in leukemias through mate pair whole genome sequencing
Anh Nhi Tran, Fulya Taylan, Vasilios Zachariadis, Ingegerd Ivanov Öfverholm, Anna Lindstrand, Francesco Vezzi, Britta Lötstedt, Magnus Nordenskjöld, Ann Nordgren, Daniel Nilsson, Gisela Barbany
PLoS One. 2018; 13(3): e0193928. Published online 2018 Mar 12. doi: 10.1371/journal.pone.0193928
PMCID:
PMC5846771
AbstractArticlePDF–4.2M
8.
Detection of Mutations in Myeloid Malignancies through Paired-Sample Analysis of Microdroplet-PCR Deep Sequencing Data
Donavan T. Cheng, Janice Cheng, Talia N. Mitchell, Aijazuddin Syed, Ahmet Zehir, Nana Yaa T. Mensah, Alifya Oultache, Khedoudja Nafa, Ross L. Levine, Maria E. Arcila, Michael F. Berger, Cyrus V. Hedvat
J Mol Diagn. 2014 Sep; 16(5): 504–518. doi: 10.1016/j.jmoldx.2014.05.006
PMCID:
PMC5707185
AbstractArticlePDF–1.3M
9.
Germline SAMD9 Mutation in Siblings with Monosomy 7 and Myelodysplastic Syndrome
Jason R. Schwartz, Shuoguo Wang, Jing Ma, Tamara Lamprecht, Michael Walsh, Guangchun Song, Susana C. Raimondi, Gang Wu, Michael F. Walsh, Rose B. McGee, Chimene Kesserwan, Kim E. Nichols, Brian E. Cauff, Raul C. Ribeiro, Marcin Wlodarski, Jeffery M. Klco
Leukemia. Author manuscript; available in PMC 2017 Nov 10.
Published in final edited form as: Leukemia. 2017 Aug; 31(8): 1827–1830. Published online 2017 May 10. doi: 10.1038/leu.2017.142
PMCID:
PMC5540771
ArticlePDF–272K
10.
NTRK3 kinase fusions in Spitz tumours
Iwei Yeh, Meng Kian Tee, Thomas Botton, A. Hunter Shain, Alyssa J. Sparatta, Alexander Gagnon, Swapna S. Vemula, Maria C. Garrido, Kenji Nakamaru, Takeshi Isoyama, Timothy H. McCalmont, Philip E. LeBoit, Boris C. Bastian
J Pathol. Author manuscript; available in PMC 2017 Nov 1.
Published in final edited form as: J Pathol. 2016 Nov; 240(3): 282–290. doi: 10.1002/path.4775
PMCID:
PMC5071153
AbstractArticlePDF–667K
11.
Chronic eosinophilic leukemia, NOS with t(5;12)(q31;p13)/ETV6-ACSL6 gene fusion: a novel variant of myeloid proliferative neoplasm with eosinophilia
Ruijun Jeanna Su, Brian A Jonas, Jeanna Welborn, Jeffrey Paul Gregg, Mingyi Chen
Hum Pathol (N Y) Author manuscript; available in PMC 2017 Sep 1.
Published in final edited form as: Hum Pathol (N Y). 2016 Sep; 5: 6–9. doi: 10.1016/j.ehpc.2015.10.001
PMCID:
PMC4957580
AbstractArticlePDF–208K
12.
Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia
Sabine Topka, Joseph Vijai, Michael F. Walsh, Lauren Jacobs, Ann Maria, Danylo Villano, Pragna Gaddam, Gang Wu, Rose B. McGee, Emily Quinn, Hiroto Inaba, Christine Hartford, Ching-hon Pui, Alberto Pappo, Michael Edmonson, Michael Y. Zhang, Polina Stepensky, Peter Steinherz, Kasmintan Schrader, Anne Lincoln, James Bussel, Steve M. Lipkin, Yehuda Goldgur, Mira Harit, Zsofia K. Stadler, Charles Mullighan, Michael Weintraub, Akiko Shimamura, Jinghui Zhang, James R. Downing, Kim E. Nichols, Kenneth Offit
PLoS Genet. 2015 Jun; 11(6): e1005262. Published online 2015 Jun 23. doi: 10.1371/journal.pgen.1005262
PMCID:
PMC4477877
AbstractArticlePDF–1.9M
13.
Neonatal Infection with Species C Adenoviruses Confirmed in Viable Cord Blood Lymphocytes
David A. Ornelles, Linda R. Gooding, C. Garnett-Benson
PLoS One. 2015; 10(3): e0119256. Published online 2015 Mar 12. doi: 10.1371/journal.pone.0119256
PMCID:
PMC4357425
AbstractArticlePDF–420K
14.
Silencing SATB1 Inhibits the Malignant Phenotype and Increases Sensitivity of Human Osteosarcoma U2OS Cells to Arsenic Trioxide
Haiying Zhang, Xuejin Su, Li Guo, Lingzhi Zhong, Wenxue Li, Zhen Yue, Xiaotong Wang, Yan Mu, Xinna Li, Ronggui Li, Zonggui Wang
Int J Med Sci. 2014; 11(12): 1262–1269. Published online 2014 Oct 2. doi: 10.7150/ijms.10038
PMCID:
PMC4196128
AbstractArticlePDF–892K
15.
ETV6 mutation in a cohort of 970 patients with hematologic malignancies
Qinrong Wang, Shasha Dong, Hong Yao, Lijun Wen, Huiying Qiu, Llili Qin, Liang Ma, Suning Chen
Haematologica. 2014 Oct; 99(10): e176–e178. doi: 10.3324/haematol.2014.104406
PMCID:
PMC4181263
ArticlePDF–240K
16.
Haploinsufficiency of ETV6 and CDKN1B in patients with acute myeloid leukemia and complex karyotype
Simone Feurstein, Frank G Rücker, Lars Bullinger, Winfried Hofmann, Georgi Manukjan, Gudrun Göhring, Ulrich Lehmann, Michael Heuser, Arnold Ganser, Konstanze Döhner, Brigitte Schlegelberger, Doris Steinemann
BMC Genomics. 2014; 15(1): 784. Published online 2014 Sep 11. doi: 10.1186/1471-2164-15-784
PMCID:
PMC4168160
AbstractArticlePDF–1.2M
17.
PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity
Gabriele Stocco, Wenjian Yang, Kristine R. Crews, William E. Thierfelder, Giuliana Decorti, Margherita Londero, Raffaella Franca, Marco Rabusin, Maria Grazia Valsecchi, Deqing Pei, Cheng Cheng, Steven W. Paugh, Laura B. Ramsey, Barthelemy Diouf, Joseph Robert McCorkle, Terreia S. Jones, Ching-Hon Pui, Mary V. Relling, William E. Evans
Hum Mol Genet. 2012 Nov 1; 21(21): 4793–4804. Published online 2012 Jul 30. doi: 10.1093/hmg/dds302
PMCID:
PMC3471396
AbstractArticlePDF–359K
18.
Rapid Detection of Prognostically Significant Fusion Transcripts in Acute Leukemia Using Simplified Multiplex Reverse Transcription Polymerase Chain Reaction
Young-Uk Cho, Hyun-Sook Chi, Chan-Jeoung Park, Seongsoo Jang, Eul-Ju Seo
J Korean Med Sci. 2012 Oct; 27(10): 1155–1161. Published online 2012 Oct 2. doi: 10.3346/jkms.2012.27.10.1155
PMCID:
PMC3468750
AbstractArticlePDF–1.4M
19.
Characterization of a newly identified ETV6-NTRK3 fusion transcript in acute myeloid leukemia
Johanna M Kralik, Wolfgang Kranewitter, Hans Boesmueller , Renate Marschon, Gertraud Tschurtschenthaler, Holger Rumpold, Kurt Wiesinger, Martin Erdel, Andreas L Petzer, Gerald Webersinke
Diagn Pathol. 2011; 6: 19. Published online 2011 Mar 15. doi: 10.1186/1746-1596-6-19
PMCID:
PMC3063188
AbstractArticlePDF–1.0M
20.
NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells
Stefan Nagel, Letizia Venturini, Grzegorz K Przybylski, Piotr Grabarczyk, Corinna Meyer, Maren Kaufmann, Karin Battmer, Christian A Schmidt, Hans G Drexler, Michaela Scherr, Roderick AF MacLeod
BMC Cancer. 2009; 9: 371. Published online 2009 Oct 19. doi: 10.1186/1471-2407-9-371
PMCID:
PMC2770077
AbstractArticlePDF–1.3M

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