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Select item 55316111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 48981652.

Impaired NFKBIE gene function decreases cellular uptake of methotrexate by down-regulating SLC19A1 expression in a human rheumatoid arthritis cell line

Hitoshi Imamura, Sawako Yoshina, Katsunori Ikari, Keiji Miyazawa, Shigeki Momohara, Shohei Mitani

Mod Rheumatol. 2016 Jul 3; 26(4): 507–516. Published online 2016 Jan 4. doi: 10.3109/14397595.2015.1112481

PMCID:: PMC4898165

Abstract Article PDF–1.2M

Select item 47394133.

Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

Lene F. Lundbo, Zitta Barrella Harboe, Louise N. Clausen, Mads V. Hollegaard, Henrik T. Sørensen, David M. Hougaard, Helle B. Konradsen, Mette Nørgaard, Thomas Benfield

EBioMedicine. 2016 Jan; 3: 93–99. Published online 2015 Dec 2. doi: 10.1016/j.ebiom.2015.11.048

PMCID:: PMC4739413

Abstract Article PDF–251K

Select item 45894864.

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

A. Hunter Shain, Maria Garrido, Thomas Botton, Eric Talevich, Iwei Yeh, J. Zachary Sanborn, Jongsuk Chung, Nicholas J. Wang, Hojabr Kakavand, Graham J. Mann, John F. Thompson, Thomas Wiesner, Ritu Roy, Adam B. Olshen, Alexander Gagnon, Joe W. Gray, Nam Huh, Joe S. Hur, Klaus J. Busam, Richard A. Scolyer, Raymond J. Cho, Rajmohan Murali, Boris C. Bastian

Nat Genet. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Nat Genet. 2015 Oct; 47(10): 1194–1199. Published online 2015 Sep 7. doi: 10.1038/ng.3382

PMCID:: PMC4589486

Article PDF–1.3M

Select item 11697385.

I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.

S T Whiteside, J C Epinat, N R Rice, A Israël

EMBO J. 1997 Mar 17; 16(6): 1413–1426. doi: 10.1093/emboj/16.6.1413

PMCID:: PMC1169738

Summary PDF–717K

Select item 3586276.

Purification, reconstitution, and I kappa B association of the c-Rel-p65 (RelA) complex, a strong activator of transcription.

S K Hansen, P A Baeuerle, F Blasi

Mol Cell Biol. 1994 Apr; 14(4): 2593–2603. doi: 10.1128/mcb.14.4.2593

PMCID:: PMC358627

Summary Page Browse PDF–2.9M

Select item 2324697.

A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription.

Z Li, G J Nabel

Mol Cell Biol. 1997 Oct; 17(10): 6184–6190. doi: 10.1128/mcb.17.10.6184

PMCID:: PMC232469

Summary PDF–1.9M

Select item 1918538.

VBP and RelA regulate avian leukosis virus long terminal repeat-enhanced transcription in B cells.

S M Curristin, K J Bird, R J Tubbs, A Ruddell

J Virol. 1997 Aug; 71(8): 5972–5981. doi: 10.1128/jvi.71.8.5972-5981.1997

PMCID:: PMC191853

Summary PDF–1.7M

Select item 474819.

I kappa B alpha-mediated inhibition of v-Rel DNA binding requires direct interaction with the RXXRXRXXC Rel/kappa B DNA-binding motif.

S Kumar, C Gélinas

Proc Natl Acad Sci U S A. 1993 Oct 1; 90(19): 8962–8966. doi: 10.1073/pnas.90.19.8962

PMCID:: PMC47481

Summary Page Browse PDF–1.4M

Select item 589424510.

Matrix metalloproteinase-9 (MMP9) is involved in the TNF-α-induced fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 cancer cells

Julian Weiler, Marieke Mohr, Kurt S. Zänker, Thomas Dittmar

Cell Commun Signal. 2018; 16: 14. Published online 2018 Apr 10. doi: 10.1186/s12964-018-0226-1

PMCID:: PMC5894245

Abstract Article PDF–2.3M

Select item 578063811.

Sporadic and reversible chromothripsis in chronic lymphocytic leukemia revealed by longitudinal genomic analysis

L Bassaganyas, S Beà, G Escaramís, C Tornador, I Salaverria, L Zapata, O Drechsel, P G Ferreira, B Rodriguez-Santiago, J M C Tubio, A Navarro, D Martín-García, C López, A Martínez-Trillos, A López-Guillermo, M Gut, S Ossowski, C López-Otín, E Campo, X Estivill

Leukemia. 2015 Mar; 29(3): 758. Published online 2015 Mar 4. doi: 10.1038/leu.2014.309

Corrects:: Leukemia. 2013 Dec; 27(12): 2376–2379.

PMCID:: PMC5780638

Correction PDF–68K

Select item 540687412.

Gene Expression Analysis before and after Treatment with Adalimumab in Patients with Ankylosing Spondylitis Identifies Molecular Pathways Associated with Response to Therapy

Marzia Dolcino, Elisa Tinazzi, Andrea Pelosi, Giuseppe Patuzzo, Francesca Moretta, Claudio Lunardi, Antonio Puccetti

Genes (Basel) 2017 Apr; 8(4): 127. Published online 2017 Apr 24. doi: 10.3390/genes8040127

PMCID:: PMC5406874

Abstract Article PDF–2.7M

Select item 530822613.

Wnt5A/Ryk signaling critically affects barrier function in human vascular endothelial cells

Tom Skaria, Esther Bachli, Gabriele Schoedon

Cell Adh Migr. 2017; 11(1): 24–38. Published online 2016 May 9. doi: 10.1080/19336918.2016.1178449

PMCID:: PMC5308226

Abstract Article PDF–1.3M

Select item 469880314.

Differential susceptibility of human pleural and peritoneal mesothelial cells to asbestos exposure

Julie Dragon, Joyce Thompson, Maximilian MacPherson, Arti Shukla

J Cell Biochem. Author manuscript; available in PMC 2016 Jan 4.

Published in final edited form as: J Cell Biochem. 2015 Aug; 116(8): 1540–1552. doi: 10.1002/jcb.25095

PMCID:: PMC4698803

Abstract Article PDF–2.3M

Select item 388540615.

Transcriptome-Wide Analysis of UTRs in Non-Small Cell Lung Cancer Reveals Cancer-Related Genes with SNV-Induced Changes on RNA Secondary Structure and miRNA Target Sites

Radhakrishnan Sabarinathan, Anne Wenzel, Peter Novotny, Xiaojia Tang, Krishna R. Kalari, Jan Gorodkin

PLoS One. 2014; 9(1): e82699. Published online 2014 Jan 8. doi: 10.1371/journal.pone.0082699

PMCID:: PMC3885406

Abstract Article PDF–1.0M

Select item 386553216.

Sporadic and reversible chromothripsis in chronic lymphocytic leukemia revealed by longitudinal genomic analysis

Leukemia. 2013 Dec; 27(12): 2376–2379. Prepublished online 2013 Apr 24. Published online 2013 May 21. doi: 10.1038/leu.2013.127

Correction in:: Leukemia. 2015 Mar; 29(3): 758.

PMCID:: PMC3865532

Article PDF–729K

Select item 372391017.

A Network Integration Approach to Predict Conserved Regulators Related to Pathogenicity of Influenza and SARS-CoV Respiratory Viruses

Hugh D. Mitchell, Amie J. Eisfeld, Amy C. Sims, Jason E. McDermott, Melissa M. Matzke, Bobbi-Jo M. Webb-Robertson, Susan C. Tilton, Nicolas Tchitchek, Laurence Josset, Chengjun Li, Amy L. Ellis, Jean H. Chang, Robert A. Heegel, Maria L. Luna, Athena A. Schepmoes, Anil K. Shukla, Thomas O. Metz, Gabriele Neumann, Arndt G. Benecke, Richard D. Smith, Ralph S. Baric, Yoshihiro Kawaoka, Michael G. Katze, Katrina M. Waters

PLoS One. 2013; 8(7): e69374. Published online 2013 Jul 25. doi: 10.1371/journal.pone.0069374

PMCID:: PMC3723910

Abstract Article PDF–2.1M

Select item 362183818.

A functional genomics screen for microRNA regulators of NF-kappaB signaling

Anthony O Olarerin-George, Lauren Anton, Yih-Chii Hwang, Michal A Elovitz, John B Hogenesch

BMC Biol. 2013; 11: 19. Published online 2013 Feb 28. doi: 10.1186/1741-7007-11-19

PMCID:: PMC3621838

Abstract Article PDF–1.5M

Select item 342573119.

Retinoic acid and tumor necrosis factor-α induced monocytic cell gene expression is regulated in part by induction of transcription factor MafB

Yao Zhang, Quiyan Chen, A. Catharine Ross

Exp Cell Res. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Exp Cell Res. 2012 Nov 1; 318(18): 2407–2416. Published online 2012 Jul 20. doi: 10.1016/j.yexcr.2012.07.011

PMCID:: PMC3425731

Abstract Article PDF–1.2M

Select item 312851820.

A nuclear factor-κB signaling pathway via protein kinase C δ regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells

Tomoyuki Masaki, Takashi Kojima, Tamaki Okabayashi, Noriko Ogasawara, Tsuyoshi Ohkuni, Kazufumi Obata, Akira Takasawa, Masaki Murata, Satoshi Tanaka, Satoshi Hirakawa, Jun Fuchimoto, Takafumi Ninomiya, Nobuhiro Fujii, Hiroyuki Tsutsumi, Tetsuo Himi, Norimasa Sawada

Mol Biol Cell. 2011 Jul 1; 22(13): 2144–2156. doi: 10.1091/mbc.E10-11-0875

PMCID:: PMC3128518

Abstract Article PDF–3.8M

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