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Select item 67699401.

Effect of Hepatitis Viruses on the Nrf2/Keap1-Signaling Pathway and Its Impact on Viral Replication and Pathogenesis

Daniela Bender, Eberhard Hildt

Int J Mol Sci. 2019 Sep; 20(18): 4659. Published online 2019 Sep 19. doi: 10.3390/ijms20184659

PMCID:: PMC6769940

Article PDF–2.3M

Select item 67426462.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Article PDF–1.2M

Select item 66424353.

FAM129B, an antioxidative protein, reduces chemosensitivity by competing with Nrf2 for Keap1 binding

Kai-Chun Cheng, Ruey-Jen Lin, Jing-Yan Cheng, Sheng-Hung Wang, Jyh-Cherng Yu, Jen-Chine Wu, Yuh-Jin Liang, Huan-Ming Hsu, John Yu, Alice L. Yu

EBioMedicine. 2019 Jul; 45: 25–38. Published online 2019 Jun 28. doi: 10.1016/j.ebiom.2019.06.022

PMCID:: PMC6642435

Article PDF–4.3M

Select item 66003224.

Methylation Density Pattern of KEAP1 Gene in Lung Cancer Cell Lines Detected by Quantitative Methylation Specific PCR and Pyrosequencing

Federico Pio Fabrizio, Angelo Sparaneo, Flavia Centra, Domenico Trombetta, Clelia Tiziana Storlazzi, Paolo Graziano, Evaristo Maiello, Vito Michele Fazio, Lucia Anna Muscarella

Int J Mol Sci. 2019 Jun; 20(11): 2697. Published online 2019 May 31. doi: 10.3390/ijms20112697

PMCID:: PMC6600322

Article PDF–2.2M

Select item 3163705.

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh, Tetsuro Ishii, Kazuhiko Igarashi, James Douglas Engel, Masayuki Yamamoto

Genes Dev. 1999 Jan 1; 13(1): 76–86. doi: 10.1101/gad.13.1.76

PMCID:: PMC316370

Article PDF–1.7M

Select item 65665556.

Effects of KEAP1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung Tumors

Angelo Sparaneo, Federico Pio Fabrizio, Annamaria la Torre, Paolo Graziano, Massimo Di Maio, Andrea Fontana, Michele Bisceglia, Antonio Rossi, Stefano Pizzolitto, Giovanna De Maglio, Antonio Tancredi, Franco Grimaldi, Teresa Balsamo, Flavia Centra, Maria Carmina Manzorra, Domenico Trombetta, Angela Pantalone, Antonio Bonfitto, Evaristo Maiello, Vito Michele Fazio, Lucia Anna Muscarella

Int J Mol Sci. 2019 May; 20(10): 2531. Published online 2019 May 23. doi: 10.3390/ijms20102531

PMCID:: PMC6566555

Article PDF–3.1M

Select item 63500427.

HOXD8/DIAPH2-AS1 epigenetically regulates PAX3 and impairs HTR-8/SVneo cell function under hypoxia

Yaling Feng, Jianxia Wang, Yue He, Heng Zhang, Minhui Jiang, Dandan Cao, Aiping Wang

Biosci Rep. 2019 Jan 31; 39(1): BSR20182022. Prepublished online 2019 Jan 9. Published online 2019 Jan 25. doi: 10.1042/BSR20182022

PMCID:: PMC6350042

Article PDF–1.0M

Select item 62916878.

Gene expression profiling: identification of gene expression in human MSC chondrogenic differentiation

Ming Gong, Tangzhao Liang, Hao Zhang, Shaochu Chen, Yawei Hu, Jianhua Zhou, Xuan Zhang, Wang Zhang, Xiaojing Geng, Xuenong Zou

Am J Transl Res. 2018; 10(11): 3555–3566. Published online 2018 Nov 15.

PMCID:: PMC6291687

Article PDF–1.5M

Select item 60544019.

Nrf2 protects stellate cells from Smad-dependent cell activation

Vincenzo Prestigiacomo, Laura Suter-Dick

PLoS One. 2018; 13(7): e0201044. Published online 2018 Jul 20. doi: 10.1371/journal.pone.0201044

PMCID:: PMC6054401

Article PDF–7.7M

Select item 600746510.

The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer

Jonathan P. Evans, Boleslaw K. Winiarski, Paul A. Sutton, Robert P. Jones, Lorenzo Ressel, Carrie A. Duckworth, D. Mark Pritchard, Zhi-Xiu Lin, Fretwell L. Vicky, Elizabeth M. Tweedle, Eithne Costello, Christopher E. Goldring, Ian M. Copple, B. Kevin Park, Daniel H. Palmer, Neil R. Kitteringham

Oncotarget. 2018 Jun 5; 9(43): 27104–27116. Published online 2018 Jun 5. doi: 10.18632/oncotarget.25497

Correction in:: Oncotarget. 2019 Jan 18; 10(6): 685.

PMCID:: PMC6007465

Article PDF–6.0M

Select item 584399711.

Sequencing of circulating tumor DNA for dynamic monitoring of gene mutations in advanced non-small cell lung cancer

Ruilian Xu, Guolin Zhong, Tanxiao Huang, Wan He, Cheng Kong, Xiaoni Zhang, Ying Wang, Ming Liu, Mingyan Xu, Shifu Chen

Oncol Lett. 2018 Mar; 15(3): 3726–3734. Published online 2018 Jan 16. doi: 10.3892/ol.2018.7808

PMCID:: PMC5843997

Article PDF–1.5M

Select item 571183412.

Pelargonidin Modulates Keap1/Nrf2 Pathway Gene Expression and Ameliorates Citrinin-Induced Oxidative Stress in HepG2 Cells

G. R. Sharath Babu, Tamatam Anand, N. Ilaiyaraja, Farhath Khanum, N. Gopalan

Front Pharmacol. 2017; 8: 868. Published online 2017 Nov 27. doi: 10.3389/fphar.2017.00868

PMCID:: PMC5711834

Article PDF–8.0M

Select item 553787413.

Suppression of Nrf2 Activity by Chestnut Leaf Extract Increases Chemosensitivity of Breast Cancer Stem Cells to Paclitaxel

Yaejin Woo, Jisun Oh, Jong-Sang Kim

Nutrients. 2017 Jul; 9(7): 760. Published online 2017 Jul 18. doi: 10.3390/nu9070760

PMCID:: PMC5537874

Article PDF–2.8M

Select item 507485214.

Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation

Joanna J. Phillips, Henry Gong, Katharine Chen, Nancy M. Joseph, Jessica van Ziffle, Lee-Way Jin, Boris C. Bastian, Andrew W. Bollen, Arie Perry, Theodore Nicolaides, David A. Solomon, Joseph T.C. Shieh

Acta Neuropathol. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Acta Neuropathol. 2016 Nov; 132(5): 757–760. Published online 2016 Sep 13. doi: 10.1007/s00401-016-1616-3

PMCID:: PMC5074852

Article PDF–278K

Select item 438301915.

Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

Michal Kovac, Carolina Navas, Stuart Horswell, Max Salm, Chiara Bardella, Andrew Rowan, Mark Stares, Francesc Castro-Giner, Rosalie Fisher, Elza C. de Bruin, Monika Kovacova, Maggie Gorman, Seiko Makino, Jennet Williams, Emma Jaeger, Angela Jones, Kimberley Howarth, James Larkin, Lisa Pickering, Martin Gore, David L. Nicol, Steven Hazell, Gordon Stamp, Tim O’Brien, Ben Challacombe, Nik Matthews, Benjamin Phillimore, Sharmin Begum, Adam Rabinowitz, Ignacio Varela, Ashish Chandra, Catherine Horsfield, Alexander Polson, Maxine Tran, Rupesh Bhatt, Luigi Terracciano, Serenella Eppenberger-Castori, Andrew Protheroe, Eamonn Maher, Mona El Bahrawy, Stewart Fleming, Peter Ratcliffe, Karl Heinimann, Charles Swanton, Ian Tomlinson

Nat Commun. 2015 Mar 19; 6: 6336. Published online 2015 Mar 19. doi: 10.1038/ncomms7336

PMCID:: PMC4383019

Article PDF–1.1M

Select item 417638716.

Ginger Compound [6]-Shogaol and Its Cysteine-Conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo

Huadong Chen, Junsheng Fu, Hao Chen, Yuhui Hu, Dominique N. Soroka, Justin R. Prigge, Edward E. Schmidt, Feng Yan, Michael B. Major, Xiaoxin Chen, Shengmin Sang

Chem Res Toxicol. 2014 Sep 15; 27(9): 1575–1585. Published online 2014 Aug 22. doi: 10.1021/tx500211x

PMCID:: PMC4176387

Article PDF–5.3M

Select item 367763317.

Novel Hematopoietic Target Genes in the NRF2-Mediated Transcriptional Pathway

Michelle R. Campbell, Mehmet Karaca, Kelly N. Adamski, Brian N. Chorley, Xuting Wang, Douglas A. Bell

Oxid Med Cell Longev. 2013; 2013: 120305. Published online 2013 May 25. doi: 10.1155/2013/120305

PMCID:: PMC3677633

Article PDF–1.8M

Select item 365435918.

Curcumin Protects Human Keratinocytes against Inorganic Arsenite-Induced Acute Cytotoxicity through an NRF2-Dependent Mechanism

Rui Zhao, Bei Yang, Linlin Wang, Peng Xue, Baocheng Deng, Guohua Zhang, Shukun Jiang, Miao Zhang, Min Liu, Jingbo Pi, Dawei Guan

Oxid Med Cell Longev. 2013; 2013: 412576. Published online 2013 Apr 21. doi: 10.1155/2013/412576

PMCID:: PMC3654359

Article PDF–2.0M

Select item 351758119.

Identification of Novel microRNAs in Post-Transcriptional Control of Nrf2 Expression and Redox Homeostasis in Neuronal, SH-SY5Y Cells

Madhusudhanan Narasimhan, Dhyanesh Patel, Dhanashree Vedpathak, Marylatha Rathinam, George Henderson, Lenin Mahimainathan

PLoS One. 2012; 7(12): e51111. Published online 2012 Dec 7. doi: 10.1371/journal.pone.0051111

PMCID:: PMC3517581

Article PDF–1.4M

Select item 340608620.

Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition

Kevin Bray, Robin Mathew, Alexandria Lau, Jurre J. Kamphorst, Jing Fan, Jim Chen, Hsin-Yi Chen, Anahita Ghavami, Mark Stein, Robert S. DiPaola, Donna Zhang, Joshua D. Rabinowitz, Eileen White

PLoS One. 2012; 7(7): e41831. Published online 2012 Jul 26. doi: 10.1371/journal.pone.0041831

PMCID:: PMC3406086

Article PDF–1.2M

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