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Select item 66964781.

Gene Expression Profiling Reveals that PXR Activation Inhibits Hepatic PPARα Activity and Decreases FGF21 Secretion in Male C57Bl6/J Mice

Sharon Ann Barretto, Frédéric Lasserre, Anne Fougerat, Lorraine Smith, Tiffany Fougeray, Céline Lukowicz, Arnaud Polizzi, Sarra Smati, Marion Régnier, Claire Naylies, Colette Bétoulières, Yannick Lippi, Hervé Guillou, Nicolas Loiseau, Laurence Gamet-Payrastre, Laila Mselli-Lakhal, Sandrine Ellero-Simatos

Int J Mol Sci. 2019 Aug; 20(15): 3767. Published online 2019 Aug 1. doi: 10.3390/ijms20153767

PMCID:: PMC6696478

Abstract Article PDF–1.8M

Select item 66607792.

YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity

Lirui Wang, Magdalena Mazagova, Chuyue Pan, Song Yang, Katharina Brandl, Jun Liu, Shannon M. Reilly, Yanhan Wang, Zhaorui Miao, Rohit Loomba, Na Lu, Qinglong Guo, Jihua Liu, Ruth T. Yu, Michael Downes, Ronald M. Evans, David A. Brenner, Alan R. Saltiel, Bruce Beutler, Bernd Schnabl

Proc Natl Acad Sci U S A. 2019 Jul 23; 116(30): 15184–15193. Published online 2019 Jul 9. doi: 10.1073/pnas.1904360116

PMCID:: PMC6660779

Abstract Article PDF–1.7M

Select item 65795333.

FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism

Cristal M. Hill, Thomas Laeger, Madeleine Dehner, Diana C. Albarado, Blaise Clarke, Desiree Wanders, Susan J. Burke, J. Jason Collier, Emily Qualls-Creekmore, Samantha M. Solon-Biet, Stephen J. Simpson, Hans-Rudolf Berthoud, Heike Munzberg, Christopher D. Morrison

Cell Rep. Author manuscript; available in PMC 2019 Jun 17.

Published in final edited form as: Cell Rep. 2019 Jun 4; 27(10): 2934–2947.e3. doi: 10.1016/j.celrep.2019.05.022

PMCID:: PMC6579533

Abstract Article PDF–1.7M

Select item 67117234.

Aging-associated impairment in metabolic compensation by subcutaneous adipose tissue promotes diet-induced fatty liver disease in mice

Hiroyoshi Taketani, Taichiro Nishikawa, Hisakazu Nakajima, Kazuki Kodo, Satoru Sugimoto, Wataru Aoi, Shin-ichi Horike, Makiko Meguro-Horike, Hiroshi Ishiba, Yuya Seko, Atsushi Umemura, Kanji Yamaguchi, Michihisa Moriguchi, Kohichiroh Yasui, Yoshito Itoh

Diabetes Metab Syndr Obes. 2019; 12: 1473–1492. Published online 2019 Aug 23. doi: 10.2147/DMSO.S214093

PMCID:: PMC6711723

Abstract Article PDF–7.0M

Select item 65839195.

Expression analysis of long non-coding RNAs in a renal ischemia-reperfusion injury model

Qiu Tao, Wang Tianyu, Zhou Jiangqiao, Chen Zhongbao, Ma Xiaoxiong, Zhang Long, Zou Jilin

Acta Cir Bras. 2019; 34(4): e201900403. Published online 2019 Apr 29. doi: 10.1590/s0102-865020190040000003

PMCID:: PMC6583919

Abstract Article PDF–2.5M

Select item 64400206.

Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons

Lien-Szu Wu, Wei-Cheng Cheng, Chia-Ying Chen, Ming-Che Wu, Yi-Chi Wang, Yu-Hsiang Tseng, Trees-Juen Chuang, C.-K. James Shen

Acta Neuropathol Commun. 2019; 7: 50. Published online 2019 Mar 29. doi: 10.1186/s40478-019-0674-x

PMCID:: PMC6440020

Abstract Article PDF–7.8M

Select item 63234667.

Gene Expression Patterns Analysis in the Supraspinatus Muscle after a Rotator Cuff Tear in a Mouse Model

Yong-Soo Lee, Ja-Yeon Kim, Hyo-Nam Kim, Dhong-Won Lee, Seok Won Chung

Biomed Res Int. 2018; 2018: 5859013. Published online 2018 Dec 23. doi: 10.1155/2018/5859013

PMCID:: PMC6323466

Abstract Article PDF–3.2M

Select item 61343278.

Lack of 17β-estradiol reduces sensitivity to insulin in the liver and muscle of male mice

Katsumi Toda, Akiko Toda, Masafumi Ono, Toshiji Saibara

Heliyon. 2018 Sep; 4(9): e00772. Published online 2018 Sep 11. doi: 10.1016/j.heliyon.2018.e00772

PMCID:: PMC6134327

Abstract Article PDF–1.3M

Select item 60938839.

The IRE1α-XBP1s pathway promotes insulin-stimulated glucose uptake in adipocytes by increasing PPARγ activity

Yoon Mi Cho, Dong Hee Kim, Kyung Hye Lee, Seong-Whan Jeong, Oh-Joo Kwon

Exp Mol Med. 2018 Aug; 50(8): 102. Published online 2018 Aug 15. doi: 10.1038/s12276-018-0131-0

PMCID:: PMC6093883

Abstract Article PDF–2.7M

Select item 568029710.

Neural-specific deletion of mitochondrial p32/C1qbp leads to leukoencephalopathy due to undifferentiated oligodendrocyte and axon degeneration

Mikako Yagi, Takeshi Uchiumi, Noriaki Sagata, Daiki Setoyama, Rie Amamoto, Yuichi Matsushima, Dongchon Kang

Sci Rep. 2017; 7: 15131. Published online 2017 Nov 9. doi: 10.1038/s41598-017-15414-5

PMCID:: PMC5680297

Abstract Article PDF–2.8M

Select item 564017811.

Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation

Satoshi Minami, Takeshi Yamamoto, Yoshitsugu Takabatake, Atsushi Takahashi, Tomoko Namba, Jun Matsuda, Tomonori Kimura, Jun-ya Kaimori, Isao Matsui, Takayuki Hamano, Hiroaki Takeda, Masatomo Takahashi, Yoshihiro Izumi, Takeshi Bamba, Taiji Matsusaka, Fumio Niimura, Yoshitaka Isaka

Autophagy. 2017; 13(10): 1629–1647. Published online 2017 Aug 16. doi: 10.1080/15548627.2017.1341464

PMCID:: PMC5640178

Abstract Article PDF–2.4M

Select item 547237512.

Androgen receptor-deficient islet β-cells exhibit alteration in genetic markers of insulin secretion and inflammation. A transcriptome analysis in the male mouse

Weiwei Xu, Tianhua Niu, Beibei Xu, Guadalupe Navarro, Matthew J. Schipma, Franck Mauvais-Jarvis

J Diabetes Complications. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: J Diabetes Complications. 2017 May; 31(5): 787–795. Published online 2017 Mar 9. doi: 10.1016/j.jdiacomp.2017.03.002