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Select item 103420991.

Pentoxifylline Inhibits TNF-α/TGF-β1-Induced Epithelial-Mesenchymal Transition via Suppressing the NF-κB Pathway and SERPINE1 Expression in CaSki Cells

Luis Arturo Palafox-Mariscal, Pablo Cesar Ortiz-Lazareno, Luis Felipe Jave-Suárez, Adriana Aguilar-Lemarroy, María Martha Villaseñor-García, José Roberto Cruz-Lozano, Karen Lilith González-Martínez, Aníbal Samael Méndez-Clemente, Alejandro Bravo-Cuellar, Georgina Hernández-Flores

Int J Mol Sci. 2023 Jul; 24(13): 10592. Published online 2023 Jun 24. doi: 10.3390/ijms241310592

PMCID:: PMC10342099

Abstract Article PDF–7.7M

Select item 99332862.

Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women

Syed Douhath Yousuf, Mohammad Ashraf Ganie, Uneeb Urwat, Syed Mudasir Andrabi, Mohammad Afzal Zargar, Mashooq Ahmad Dar, Mir Manzoor-ul-Rehman, Syed Mudassar, Fouzia Rashid

BMC Womens Health. 2023; 23: 68. Published online 2023 Feb 15. doi: 10.1186/s12905-023-02187-5

PMCID:: PMC9933286

Abstract Article PDF–2.8M

Select item 83857723.

Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis

Florence Jeny, Jean-François Bernaudin, Dominique Valeyre, Marianne Kambouchner, Marina Pretolani, Hilario Nunes, Carole Planès, Valérie Besnard

Front Immunol. 2021; 12: 719009. Published online 2021 Aug 11. doi: 10.3389/fimmu.2021.719009

PMCID:: PMC8385772

Abstract Article PDF–4.2M

Select item 80863014.

Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis

Simeng Liu, Zhimin Huang, Anna Tang, Xiaoqing Wu, Jeffrey Aube, Liang Xu, Changying Xing, Yufeng Huang

Clin Sci (Lond) Author manuscript; available in PMC 2021 Apr 30.

Published in final edited form as: Clin Sci (Lond). 2020 Jun 26; 134(12): 1433–1448. doi: 10.1042/CS20200193

PMCID:: PMC8086301

Abstract Article PDF–1.9M

Select item 74286535.

Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia

Shungang Zhang, Joshua D. Breidenbach, Fatimah K. Khalaf, Prabhatchandra R. Dube, Chrysan J. Mohammed, Apurva Lad, Stanislaw Stepkowski, Terry D. Hinds, Sivarajan Kumarasamy, Andrew Kleinhenz, Jiang Tian, Deepak Malhotra, David J. Kennedy, Christopher J. Cooper, Steven T. Haller

J Am Heart Assoc. 2020 Apr 7; 9(7): e014072. Published online 2020 Mar 21. doi: 10.1161/JAHA.119.014072

PMCID:: PMC7428653

Abstract Article PDF–2.7M

Select item 64210516.

Xenogeneic Transplantation of Human Placenta-Derived Mesenchymal Stem Cells Alleviates Renal Injury and Reduces Inflammation in a Mouse Model of Lupus Nephritis

Juan Liu, Xuehong Lu, Yan Lou, Yong Cai, Wenpeng Cui, Jing Wang, Ping Nie, Liangmei Chen, Bing Li, Ping Luo

Biomed Res Int. 2019; 2019: 9370919. Published online 2019 Mar 3. doi: 10.1155/2019/9370919

PMCID:: PMC6421051

Abstract Article PDF–2.7M

Select item 63326057.

Association of uPA and PAI-1 tumor levels and 4G/5G variants of PAI-1 gene with disease outcome in luminal HER2-negative node-negative breast cancer patients treated with adjuvant endocrine therapy

Marko Jevrić, Ivana Z. Matić, Ana Krivokuća, Marija Đorđić Crnogorac, Irina Besu, Ana Damjanović, Mirjana Branković-Magić, Zorka Milovanović, Dušica Gavrilović, Snezana Susnjar, Darija Kisić Tepavčević, Tatjana Stanojković

BMC Cancer. 2019; 19: 71. Published online 2019 Jan 15. doi: 10.1186/s12885-018-5255-z

PMCID:: PMC6332605

Abstract Article PDF–1018K

Select item 61376738.

Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis

Kate A. Parham, Julia R. Zebol, Katie L. Tooley, Wai Y. Sun, Lachlan M. Moldenhauer, Michaelia P. Cockshell, Briony L. Gliddon, Paul A. Moretti, Gabor Tigyi, Stuart M. Pitson, Claudine S. Bonder

FASEB J. 2015 Sep; 29(9): 3638–3653. Published online 2015 May 18. doi: 10.1096/fj.14-261289

PMCID:: PMC6137673

Abstract Article

Select item 61306689.

Effects of astaxanthin on blood coagulation, fibrinolysis and platelet aggregation in hyperlipidemic rats

Zu-Yue Deng, Wei-Guang Shan, Shen-Feng Wang, Meng-Mei Hu, Yan Chen

Pharm Biol. 2017; 55(1): 663–672. Published online 2016 Dec 12. doi: 10.1080/13880209.2016.1261905

PMCID:: PMC6130668

Abstract Article PDF–1.0M

Select item 572659410.

Sickle Mice Are Sensitive to Hypoxia/Ischemia-Induced Stroke, but Respond to Tissue Plasminogen Activator Treatment

Yu-Yo Sun, Jolly Lee, Henry Huang, Mary B. Wagner, Clinton H. Joiner, David R. Archer, Chia-Yi Kuan

Stroke. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Stroke. 2017 Dec; 48(12): 3347–3355. Published online 2017 Nov 10. doi: 10.1161/STROKEAHA.117.018334

PMCID:: PMC5726594

Abstract Article PDF–1.0M

Select item 537826011.

Vasohibin‐2 is required for epithelial–mesenchymal transition of ovarian cancer cells by modulating transforming growth factor‐β signaling

Rie Norita, Yasuhiro Suzuki, Yutaka Furutani, Kazuki Takahashi, Yasuhiro Yoshimatsu, Katarzyna A. Podyma‐Inoue, Tetsuro Watabe, Yasufumi Sato

Cancer Sci. 2017 Mar; 108(3): 419–426. Published online 2017 Apr 3. doi: 10.1111/cas.13157

PMCID:: PMC5378260

Abstract Article PDF–1.4M

Select item 535574512.

Oxymatrine inhibits the migration of human colorectal carcinoma RKO cells via inhibition of PAI-1 and the TGF-β1/Smad signaling pathway

Xiaoyu Wang, Chun Liu, Jiaqi Wang, Yue Fan, Zhenghua Wang, Yuanyuan Wang

Oncol Rep. 2017 Feb; 37(2): 747–753. Published online 2016 Dec 7. doi: 10.3892/or.2016.5292

PMCID:: PMC5355745

Abstract Article PDF–772K

Select item 532530913.

Trichostatin A attenuates ventilation-augmented epithelial-mesenchymal transition in mice with bleomycin-induced acute lung injury by suppressing the Akt pathway

Li-Fu Li, Chung-Shu Lee, Chang-Wei Lin, Ning-Hung Chen, Li-Pang Chuang, Chen-Yiu Hung, Yung-Yang Liu

PLoS One. 2017; 12(2): e0172571. Published online 2017 Feb 24. doi: 10.1371/journal.pone.0172571

PMCID:: PMC5325309

Abstract Article PDF–4.5M

Select item 529358814.

Resveratrol ameliorates renal injury in spontaneously hypertensive rats by inhibiting renal micro-inflammation

Hai-Yan Xue, Li Yuan, Ying-Jie Cao, Ya-Ping Fan, Xiao-Lan Chen, Xin-Zhong Huang

Biosci Rep. 2016 Jun; 36(3): e00339. Prepublished online 2016 Apr 19. Published online 2016 Jun 3. doi: 10.1042/BSR20160035

PMCID:: PMC5293588

Abstract Article PDF–1.1M

Select item 523740315.

Targeted disruption of Cd40 in a genetically hypertensive rat model attenuates renal fibrosis and proteinuria, independent of blood pressure

Steven T. Haller, Sivarajan Kumarasamy, David A. Folt, Leah M. Wuescher, Stanislaw Stepkowski, Manish Karamchandani, Harshal Waghulde, Blair Mell, Muhammad Chaudhry, Kyle Maxwell, Siddhi Upadhyaya, Christopher A. Drummond, Jiang Tian, Wanda E. Filipiak, Thomas L. Saunders, Joseph I. Shapiro, Bina Joe, Christopher J. Cooper

Kidney Int. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: Kidney Int. 2017 Feb; 91(2): 365–374. Published online 2016 Sep 28. doi: 10.1016/j.kint.2016.08.015

PMCID:: PMC5237403

Abstract Article PDF–1.6M

Select item 488855516.

p53- and PAI-1-mediated induction of C-X-C chemokines and CXCR2: importance in pulmonary inflammation due to cigarette smoke exposure

Nivedita Tiwari, Amarnath S. Marudamuthu, Yoshikazu Tsukasaki, Mitsuo Ikebe, Jian Fu, Sreerama Shetty

Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15; 310(6): L496–L506. Published online 2016 Jan 8. doi: 10.1152/ajplung.00290.2015

PMCID:: PMC4888555

Abstract Article

Select item 448321617.

mRNA expression of genes involved in inflammation and haemostasis in equine fibroblast-like synoviocytes following exposure to lipopolysaccharide, fibrinogen and thrombin

Stine Mandrup Andreassen, Lise C. Berg, Søren Saxmose Nielsen, Annemarie T. Kristensen, Stine Jacobsen

BMC Vet Res. 2015; 11: 141. Published online 2015 Jun 27. doi: 10.1186/s12917-015-0448-z

PMCID:: PMC4483216

Abstract Article PDF–1.3M

Select item 441682118.

Plasminogen Activator Inhibitor-1 in Cigarette Smoke Exposure and Influenza A Virus Infection-Induced Lung Injury

Yashodhar P. Bhandary, Shwetha K. Shetty, Amarnath S. Marudamuthu, Krishna K. Midde, Hong-Long Ji, Homoyoun Shams, Renuka Subramaniam, Jian Fu, Steven Idell, Sreerama Shetty

PLoS One. 2015; 10(5): e0123187. Published online 2015 May 1. doi: 10.1371/journal.pone.0123187

PMCID:: PMC4416821

Abstract Article PDF–10M

Select item 436275419.

A PAI-1 mutant retards diabetic nephropathy in db/db mice through protecting podocytes

Jiandong Zhang, Chunyan Gu, Daniel A. Lawrence, Alfred K. Cheung, Yufeng Huang

Exp Physiol. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Exp Physiol. 2014 May 1; 99(5): 802–815. Published online 2014 Jan 17. doi: 10.1113/expphysiol.2013.077610

PMCID:: PMC4362754

Abstract Article PDF–1.5M

Select item 413475120.

The Basic Helix-Loop-Helix/Leucine Zipper Transcription Factor USF2 Integrates Serum-Induced PAI-1 Expression and Keratinocyte Growth

Li Qi, Craig E. Higgins, Stephen P. Higgins, Brian K. Law, Tessa M. Simone, Paul J. Higgins

J Cell Biochem. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: J Cell Biochem. 2014 Oct; 115(10): 1840–1847. doi: 10.1002/jcb.24861

PMCID:: PMC4134751

Abstract Article PDF–816K

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