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Select item 45947551.

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside of the crypt base stem cell niche

Hayley Davis, Shazia Irshad, Mukesh Bansal, Hannah Rafferty, Tatjana Boitsova, Chiara Bardella, Emma Jaeger, Annabelle Lewis, Luke Freeman-Mills, Francesc Castro Giner, Pedro Rodenas-Cuadrado, Sreelakshmi Mallappa, Susan Clark, Huw Thomas, Rosemary Jeffery, Richard Poulsom, Manuel Rodriguez-Justo, Marco Novelli, Runjan Chetty, Andrew Silver, Owen James Sansom, Florian R Greten, Lai Mun Wang, James Edward East, Ian Tomlinson, Simon John Leedham

Nat Med. Author manuscript; available in PMC 2015 Oct 6.

Published in final edited form as: Nat Med. 2015 Jan; 21(1): 62–70. Published online 2014 Dec 1. doi: 10.1038/nm.3750

PMCID:: PMC4594755

Abstract Article PDF–3.5M

Select item 5014342.

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways.

J R Jass, K G Biden, M C Cummings, L A Simms, M Walsh, E Schoch, S J Meltzer, C Wright, J Searle, J Young, B A Leggett

J Clin Pathol. 1999 Jun; 52(6): 455–460. doi: 10.1136/jcp.52.6.455

PMCID:: PMC501434

Summary Page Browse PDF–1.7M

Select item 16023783.

BRAF Mutations in Aberrant Crypt Foci and Hyperplastic Polyposis

Robyn Beach, Annie On-On Chan, Tsung-Teh Wu, Jill A. White, Jeffrey S. Morris, Simon Lunagomez, Russell R. Broaddus, Jean-Pierre J. Issa, Stanley R. Hamilton, Asif Rashid

Am J Pathol. 2005 Apr; 166(4): 1069–1075. doi: 10.1016/S0002-9440(10)62327-9

PMCID:: PMC1602378

Abstract Article PDF–586K

Select item 17271134.

Infrequent K-ras codon 12 mutation in serrated adenomas of human colorectum

Y Ajioka, H Watanabe, J Jass, Y Yokota, M Kobayashi, K Nishikura

Gut. 1998 May; 42(5): 680–684. doi: 10.1136/gut.42.5.680

PMCID:: PMC1727113

Summary PDF–208K

Select item 17741305.

BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum

T Kambara, L A Simms, V L J Whitehall, K J Spring, C V A Wynter, M D Walsh, M A Barker, S Arnold, A McGivern, N Matsubara, N Tanaka, T Higuchi, J Young, J R Jass, B A Leggett

Gut. 2004 Aug; 53(8): 1137–1144. doi: 10.1136/gut.2003.037671

PMCID:: PMC1774130

Abstract Article PDF–186K

Select item 18506456.

Concordant CpG Island Methylation in Hyperplastic Polyposis

Annie On-On Chan, Jean-Pierre J. Issa, Jeffrey S. Morris, Stanley R. Hamilton, Asif Rashid

Am J Pathol. 2002 Feb; 160(2): 529–536. doi: 10.1016/S0002-9440(10)64872-9

PMCID:: PMC1850645

Abstract Article PDF–273K

Select item 18564237.

Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis

P Minoo, K Baker, R Goswami, G Chong, W D Foulkes, A R Ruszkiewicz, M Barker, D Buchanan, J Young, J R Jass

Gut. 2006 Oct; 55(10): 1467–1474. doi: 10.1136/gut.2005.082859

PMCID:: PMC1856423

Abstract Article PDF–999K

Select item 18680948.

Frequent CpG Island Methylation in Serrated Adenomas of the Colorectum

Seun-Ja Park, Asif Rashid, Jae-Hyuk Lee, Sang Geol Kim, Stanley R. Hamilton, Tsung-Teh Wu

Am J Pathol. 2003 Mar; 162(3): 815–822. doi: 10.1016/S0002-9440(10)63878-3

PMCID:: PMC1868094

Abstract Article PDF–479K

Select item 25534199.

BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis?

Sérgia Velho, Cátia Moutinho, Luís Cirnes, Cristina Albuquerque, Richard Hamelin, Fernando Schmitt, Fátima Carneiro, Carla Oliveira, Raquel Seruca

BMC Cancer. 2008; 8: 255. Published online 2008 Sep 9. doi: 10.1186/1471-2407-8-255

PMCID:: PMC2553419

Abstract Article PDF–278K

Select item 278344910.

Analysis of Families with Lynch Syndrome Complicated by Advanced Serrated Neoplasia: The Importance of Pathology Review and Pedigree Analysis

Michael D Walsh, Daniel D Buchanan, Rhiannon Walters, Aedan Roberts, Sven Arnold, Diane McKeone, Mark Clendenning, Andrew R Ruszkiewicz, Mark A Jenkins, John L Hopper, Jack Goldblatt, Jillian George, Graeme K Suthers, Kerry Phillips, Graeme P Young, Finlay Macrae, Musa Drini, Michael O Woods, Susan Parry, Jeremy R Jass, Joanne P Young

Fam Cancer. Author manuscript; available in PMC 2010 Feb 25.

Published in final edited form as: Fam Cancer. 2009; 8(4): 313–323. Published online 2009 Feb 25. doi: 10.1007/s10689-009-9238-8

PMCID:: PMC2783449

Abstract Article PDF–900K

Select item 312435611.

A Serrated Colorectal Cancer Pathway Predominates over the Classic WNT Pathway in Patients with Hyperplastic Polyposis Syndrome

Karam S. Boparai, Evelien Dekker, Mirjam M. Polak, Alex R. Musler, Susanne van Eeden, Carel J.M. van Noesel

Am J Pathol. 2011 Jun; 178(6): 2700–2707. doi: 10.1016/j.ajpath.2011.02.023

PMCID:: PMC3124356

Abstract Article PDF–1.0M

Select item 336044312.

Serrated polyposis syndrome: Molecular, pathological and clinical aspects

Carla Guarinos, Cristina Sánchez-Fortún, María Rodríguez-Soler, Cristina Alenda, Artemio Payá, Rodrigo Jover

World J Gastroenterol. 2012 May 28; 18(20): 2452–2461. Published online 2012 May 28. doi: 10.3748/wjg.v18.i20.2452

PMCID:: PMC3360443

Abstract Article PDF–1.0M

Select item 449096113.

TFF2-CXCR4 Axis is Associated with BRAF V600E Colon Cancer

Manish K. Gala, Thomas Austin, Shuji Ogino, Andrew T. Chan

Cancer Prev Res (Phila) Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Cancer Prev Res (Phila). 2015 Jul; 8(7): 614–619. Published online 2015 Apr 21. doi: 10.1158/1940-6207.CAPR-14-0444

PMCID:: PMC4490961

Abstract Article PDF–544K

Select item 1115926914.

Genetic and epigenetic changes in aberrant crypt foci and serrated polyps

Yutaka Suehiro, Yuji Hinoda

Cancer Sci. 2008 Jun; 99(6): 1071–1076. Published online 2008 Mar 31. doi: 10.1111/j.1349-7006.2008.00784.x

PMCID:: PMC11159269

Abstract Article PDF–168K

Select item 461121015.

Serrated neoplasia of the colorectum

Nathan T Harvey, Andrew Ruszkiewicz

World J Gastroenterol. 2007 Jul 28; 13(28): 3792–3798. Published online 2007 Jul 28. doi: 10.3748/wjg.v13.i28.3792

PMCID:: PMC4611210

Abstract Article PDF–2.3M

Select item 461198816.

The Mendelian colorectal cancer syndromes

Ian Tomlinson

Ann Clin Biochem. 2015 Nov; 52(6): 690–692. doi: 10.1177/0004563215597944

PMCID:: PMC4611988

Abstract Article PDF–344K

Select item 499029217.

Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities

Patrícia Silva, Cristina Albuquerque, Pedro Lage, Vanessa Fontes, Ricardo Fonseca, Inês Vitoriano, Bruno Filipe, Paula Rodrigues, Susana Moita, Sara Ferreira, Rita Sousa, Isabel Claro, Carlos Nobre Leitão, Paula Chaves, António Dias Pereira

Int J Mol Med. 2016 Sep; 38(3): 687–702. Published online 2016 Jul 5. doi: 10.3892/ijmm.2016.2666

PMCID:: PMC4990292

Abstract Article PDF–705K

Select item 587394018.

Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile

Somaye Dehghanizadeh, Vahid Khoddami, Timothy L. Mosbruger, Sue S. Hammoud, Kornelia Edes, Therese S. Berry, Michelle Done, Wade S. Samowitz, James A. DiSario, Daniel G. Luba, Randall W. Burt, David A. Jones

PLoS One. 2018; 13(3): e0192499. Published online 2018 Mar 28. doi: 10.1371/journal.pone.0192499

PMCID:: PMC5873940

Abstract Article PDF–5.3M

Select item 603777319.

Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis

Giorgia Mori, Simone Rampelli, Beatrice Silvia Orena, Claudia Rengucci, Giulia De Maio, Giulia Barbieri, Alessandro Passardi, Andrea Casadei Gardini, Giovanni Luca Frassineti, Stefano Gaiarsa, Alessandra M. Albertini, Guglielmina Nadia Ranzani, Daniele Calistri, Maria Rosalia Pasca

Sci Rep. 2018; 8: 10329. Published online 2018 Jul 9. doi: 10.1038/s41598-018-28671-9

PMCID:: PMC6037773

Abstract Article PDF–1.7M

Select item 608682320.

RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers

Lochlan J. Fennell, Mark Clendenning, Diane M. McKeone, Saara H. Jamieson, Samanthy Balachandran, Jennifer Borowsky, John Liu, Futoshi Kawamata, Catherine E. Bond, Christophe Rosty, Matthew E. Burge, Daniel D. Buchanan, Barbara A. Leggett, Vicki L. J. Whitehall

Fam Cancer. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Fam Cancer. 2018 Jan; 17(1): 63–69. doi: 10.1007/s10689-017-0003-0

PMCID:: PMC6086823

Abstract Article PDF–506K

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