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Select item 53038981.

FHL2 Regulates Natural Killer Cell Development and Activation during Streptococcus pneumoniae Infection

Thomas Baranek, Eric Morello, Alexandre Valayer, Rose-France Aimar, Déborah Bréa, Clemence Henry, Anne-Gaelle Besnard, Emilie Dalloneau, Antoine Guillon, Pierre-François Dequin, Emilie Narni-Mancinelli, Eric Vivier, Fabrice Laurent, Yu Wei, Christophe Paget, Mustapha Si-Tahar

Front Immunol. 2017; 8: 123. Published online 2017 Feb 13. doi: 10.3389/fimmu.2017.00123

PMCID:: PMC5303898

Abstract Article PDF–7.9M

Select item 61132072.

PARP12 (ARTD12) suppresses hepatocellular carcinoma metastasis through interacting with FHL2 and regulating its stability

Changjuan Shao, Yangyang Qiu, Juan Liu, Huan Feng, Suqin Shen, Hexige Saiyin, Wenbo Yu, Youheng Wei, Long Yu, Wei Su, Jiaxue Wu

Cell Death Dis. 2018 Sep; 9(9): 856. Published online 2018 Aug 28. doi: 10.1038/s41419-018-0906-1

PMCID:: PMC6113207

Abstract Article PDF–2.1M

Select item 60525873.

Bone marrow derived mesenchymal stem cells ameliorate inflammatory response in an in vitro model of familial hemophagocytic lymphohistiocytosis 2

Handan Sevim, Yusuf Çetin Kocaefe, Mehmet Ali Onur, Duygu Uçkan-Çetinkaya, Özer Aylin Gürpınar

Stem Cell Res Ther. 2018; 9: 198. Published online 2018 Jul 18. doi: 10.1186/s13287-018-0941-y

PMCID:: PMC6052587

Abstract Article PDF–1.2M

Select item 59750904.

The FHL2 Regulation in the Transcriptional Circuitry of Human Cancers

Cyanne Ye Cao, Simon Wing-Fai Mok, Vincent Wing-Sang Cheng, Stephen Kwok-Wing Tsui

Gene. Author manuscript; available in PMC 2018 May 30.

Published in final edited form as: Gene. 2015 Nov 1; 572(1): 1–7. Published online 2015 Jul 26. doi: 10.1016/j.gene.2015.07.043

PMCID:: PMC5975090

Article PDF–945K

Select item 58244235.

FHL2 promotes tubular epithelial‐to‐mesenchymal transition through modulating β‐catenin signalling

Ting Cai, Danqin Sun, Ying Duan, Yumei Qiu, Chunsun Dai, Junwei Yang, Weichun He

J Cell Mol Med. 2018 Mar; 22(3): 1684–1695. Published online 2017 Nov 29. doi: 10.1111/jcmm.13446

PMCID:: PMC5824423

Abstract Article PDF–1.0M

Select item 55359746.

Autophagy Induced FHL2 Upregulation Promotes IL-6 Production by Activating the NF-κB Pathway in Mouse Aortic Endothelial Cells after Exposure to PM2.5

Wen-Rong Xia, Wenliang Fu, Qin Wang, Xiaoming Zhu, Wei-Wei Xing, Min Wang, Dong-Qun Xu, Dong-Gang Xu

Int J Mol Sci. 2017 Jul; 18(7): 1484. Published online 2017 Jul 17. doi: 10.3390/ijms18071484

PMCID:: PMC5535974

Abstract Article PDF–2.0M

Select item 55222007.

FHL2 interacts with iASPP and impacts the biological functions of leukemia cells

Wenting Lu, Tengteng Yu, Shuang Liu, Saisai Li, Shouyun Li, Jia Liu, Yingxi Xu, Haiyan Xing, Zheng Tian, Kejing Tang, Qing Rao, Jianxiang Wang, Min Wang

Oncotarget. 2017 Jun 20; 8(25): 40885–40895. Published online 2017 Mar 28. doi: 10.18632/oncotarget.16617

PMCID:: PMC5522200

Abstract Article PDF–6.0M

Select item 54775538.

LIM-Only Protein FHL2 Is a Negative Regulator of Transforming Growth Factor β1 Expression

Jennifer Dahan, Florence Levillayer, Tian Xia, Yann Nouët, Catherine Werts, Martine Fanton d'Andon, Minou Adib-Conquy, Anne-Marie Cassard-Doulcier, Varun Khanna, Ju Chen, Thierry Tordjmann, Marie-Annick Buendia, Grégory Jouvion, Yu Wei

Mol Cell Biol. 2017 May 15; 37(10): e00636-16. Prepublished online 2017 Feb 21. Published online 2017 May 2. doi: 10.1128/MCB.00636-16

PMCID:: PMC5477553

Abstract Article PDF–3.5M

Select item 53991459.

Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells

H Jin, K Lee, Y-H Kim, H K Oh, Y-I Maeng, T-H Kim, D-S Suh, J Bae

Oncogene. 2016 Sep 29; 35(39): 5106–5118. Published online 2016 Mar 14. doi: 10.1038/onc.2016.54

PMCID:: PMC5399145

Abstract Article PDF–2.6M

Select item 642901310.

The LIM-Only Protein FHL2 is involved in Autophagy to Regulate the Development of Skeletal Muscle Cell

Zihao Liu, Shunshun Han, Yan Wang, Can Cui, Qing Zhu, Xiaosong Jiang, Chaowu Yang, Huarui Du, Chunlin Yu, Qingyun Li, Haorong He, Xiaoxu Shen, Yuqi Chen, Yao Zhang, Lin Ye, Zhichao Zhang, Diyan Li, Xiaoling Zhao, Huadong Yin

Int J Biol Sci. 2019; 15(4): 838–846. Published online 2019 Mar 1. doi: 10.7150/ijbs.31371

PMCID:: PMC6429013

Abstract Article PDF–1.6M

Select item 514129011.

FOXK1 interaction with FHL2 promotes proliferation, invasion and metastasis in colorectal cancer

M Wu, J Wang, W Tang, X Zhan, Y Li, Y Peng, X Huang, Y Bai, J Zhao, A Li, C Chen, Y Chen, H Peng, Y Ren, G Li, S Liu, J Wang

Oncogenesis. 2016 Nov; 5(11): e271. Published online 2016 Nov 28. doi: 10.1038/oncsis.2016.68

PMCID:: PMC5141290

Abstract Article PDF–4.1M

Select item 509863512.

Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression

Naotaka Nakazawa, Aneesh R. Sathe, G. V. Shivashankar, Michael P. Sheetz

Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44): E6813–E6822. Published online 2016 Oct 14. doi: 10.1073/pnas.1608210113

PMCID:: PMC5098635

Abstract Article PDF–1.8M

Select item 497334913.

The four and a half LIM domains 2 (FHL2) regulates ovarian granulosa cell tumor progression via controlling AKT1 transcription

G Hua, C He, X Lv, L Fan, C Wang, S W Remmenga, K J Rodabaugh, L Yang, S M Lele, P Yang, A R Karpf, J S Davis, C Wang

Cell Death Dis. 2016 Jul; 7(7): e2297. Published online 2016 Jul 14. doi: 10.1038/cddis.2016.207

PMCID:: PMC4973349

Abstract Article PDF–3.9M

Select item 495049214.

Plumbagin exhibits an anti-proliferative effect in human osteosarcoma cells by downregulating FHL2 and interfering with Wnt/β-catenin signalling

Yuan-Liang Xue, Xiang-Qi Meng, Long-Jun Ma, Zhen Yuan

Oncol Lett. 2016 Aug; 12(2): 1095–1100. Published online 2016 Jun 15. doi: 10.3892/ol.2016.4725

PMCID:: PMC4950492

Abstract Article PDF–749K

Select item 493315915.

Mammalian Actin-binding Protein-1/Hip-55 Interacts with FHL2 and Negatively Regulates Cell Invasion

Lindsy R. Boateng, David Bennin, Sofia De Oliveira, Anna Huttenlocher

J Biol Chem. 2016 Jul 1; 291(27): 13987–13998. Published online 2016 Apr 26. doi: 10.1074/jbc.M116.725739

PMCID:: PMC4933159

Abstract Article PDF–3.7M

Select item 469484016.

KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2

Qingqing Yan, Wenjing Zhang, Yao Wu, Meiyan Wu, Mengnan Zhang, Xinpeng Shi, Jinjun Zhao, Qingzhen Nan, Ye Chen, Long Wang, Tianming Cheng, Jiachu Li, Yang Bai, Side Liu, Jide Wang

Oncotarget. 2015 Sep 22; 6(28): 25402–25417. Published online 2015 Jul 15. doi: 10.18632/oncotarget.4517

PMCID:: PMC4694840

Abstract Article PDF–4.6M

Select item 447814417.

FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy

Inbal Rachmin, Eden Amsalem, Eliahu Golomb, Ronen Beeri, Dan Gilon, Pengfei Fang, Hovav Nechushtan, Gillian Kay, Min Guo, Peter Li Yiqing, Roger S-Y Foo, David E. Fisher, Ehud Razin, Sagi Tshori

Int J Cardiol. Author manuscript; available in PMC 2016 Sep 15.

Published in final edited form as: Int J Cardiol. 2015 Sep 15; 195: 85–94. Published online 2015 May 20. doi: 10.1016/j.ijcard.2015.05.108