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Select item 13836821.

Quantitative model of Ras–phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly

Harjeet Kaur, Chang Shin Park, Jodee M. Lewis, Jason M. Haugh

Biochem J. 2006 Jan 1; 393(Pt 1): 235–243. Prepublished online 2005 Sep 14. Published online 2005 Dec 12. doi: 10.1042/BJ20051022

PMCID:: PMC1383682

Abstract Article PDF–389K

Select item 26706692.

cAMP-GEF cytoprotection by Src tyrosine kinase activation of phosphoinositide-3-kinase p110 β/α in rat hepatocytes

Anna Gates, Simon Hohenester, M. Sawkat Anwer, Cynthia R. L. Webster

Am J Physiol Gastrointest Liver Physiol. 2009 Apr; 296(4): G764–G774. Published online 2009 Feb 5. doi: 10.1152/ajpgi.90622.2008

PMCID:: PMC2670669

Abstract Article

Select item 27559653.

Adenomatous Polyposis Coli and Asef Function Downstream of Hepatocyte Growth Factor and Phosphatidylinositol 3-Kinase

Yoshihiro Kawasaki, Shinnosuke Tsuji, Masaki Sagara, Kanae Echizen, Yoko Shibata, Tetsu Akiyama

J Biol Chem. 2009 Aug 14; 284(33): 22436–22443. Published online 2009 Jun 12. doi: 10.1074/jbc.M109.020768

PMCID:: PMC2755965

Abstract Article PDF–1.6M

Select item 65273754.

ARHGEF4-mediates the actin cytoskeleton reorganization of hepatic stellate cells in 3-dimensional collagen matrices

Xiaowei Zhang, Lan Sun, Wei Chen, Shanna Wu, Yanmeng Li, Xiaojin Li, Bei Zhang, Jingyi Yao, Huan Wang, Anjian Xu

Cell Adh Migr. 2019; 13(1): 169–181. Published online 2019 Mar 24. doi: 10.1080/19336918.2019.1594497

PMCID:: PMC6527375

Abstract Article PDF–2.5M

Select item 27644135.

Novel susceptibility locus at chromosome 6q16.3-22.31 in a family with GEFS+

A Poduri, Y Wang, D Gordon, S Barral-Rodriguez, C Barker-Cummings, A Ulgen, V Chitsazzadeh, R S. Hill, N Risch, W A. Hauser, T A. Pedley, C A. Walsh, R Ottman

Neurology. 2009 Oct 20; 73(16): 1264–1272. doi: 10.1212/WNL.0b013e3181bd10d3

PMCID:: PMC2764413

Abstract Article PDF–3.3M

Select item 24949376.

Dissociation of Rac1(GDP)·RhoGDI Complexes by the Cooperative Action of Anionic Liposomes Containing Phosphatidylinositol 3,4,5-Trisphosphate, Rac Guanine Nucleotide Exchange Factor, and GTP

Yelena Ugolev, Yevgeny Berdichevsky, Carolyn Weinbaum, Edgar Pick

J Biol Chem. 2008 Aug 8; 283(32): 22257–22271. doi: 10.1074/jbc.M800734200

PMCID:: PMC2494937

Abstract Article PDF–862K

Select item 56668307.

Interaction between Rho GTPases and 14-3-3 Proteins

Daniel Brandwein, Zhixiang Wang

Int J Mol Sci. 2017 Oct; 18(10): 2148. Published online 2017 Oct 15. doi: 10.3390/ijms18102148

PMCID:: PMC5666830

Abstract Article PDF–769K

Select item 22688138.

A SPIKE1 signaling complex controls actin-dependent cell morphogenesis through the heteromeric WAVE and ARP2/3 complexes

Dipanwita Basu, Jie Le, Taya Zakharova, Eileen L. Mallery, Daniel B. Szymanski

Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10): 4044–4049. Published online 2008 Feb 28. doi: 10.1073/pnas.0710294105

PMCID:: PMC2268813

Abstract Article PDF–1.0M

Select item 21560389.

Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide Dependent Grp1 Family Arf GTPase Exchange Factors

Jonathan P. DiNitto, Anna Delprato, Meng-Tse Gabe Lee, Thomas C. Cronin, Shaohui Huang, Adilson Guilherme, Michael P. Czech, David G. Lambright

Mol Cell. Author manuscript; available in PMC 2007 Dec 26.

Published in final edited form as: Mol Cell. 2007 Nov 30; 28(4): 569–583. doi: 10.1016/j.molcel.2007.09.017

PMCID:: PMC2156038

Abstract Article PDF–4.3M

Select item 145701710.

A Phosphatidylinositol-3-Kinase-Dependent Signal Transition Regulates ARF1 and ARF6 during Fcγ Receptor-Mediated Phagocytosis

Peter Beemiller, Adam D Hoppe, Joel A Swanson

PLoS Biol. 2006 Jun; 4(6): e162. Published online 2006 May 9. doi: 10.1371/journal.pbio.0040162

PMCID:: PMC1457017

Abstract Article PDF–602K

Select item 324889511.

Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton

Andrea L. Marat, Maria S. Ioannou, Peter S. McPherson

Mol Biol Cell. 2012 Jan 1; 23(1): 163–175. doi: 10.1091/mbc.E11-05-0474

PMCID:: PMC3248895

Abstract Article PDF–5.5M

Select item 55600912.

The neurotrophin-3 receptor TrkC directly phosphorylates and activates the nucleotide exchange factor Dbs to enhance Schwann cell migration

Junji Yamauchi, Jonah R. Chan, Yuki Miyamoto, Gozoh Tsujimoto, Eric M. Shooter

Proc Natl Acad Sci U S A. 2005 Apr 5; 102(14): 5198–5203. Published online 2005 Mar 9. doi: 10.1073/pnas.0501160102

PMCID:: PMC556009

Abstract Article PDF–578K

Select item 454364513.

The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells

Christina M. Lucato, Michelle L. Halls, Lisa M. Ooms, Heng-Jia Liu, Christina A. Mitchell, James C. Whisstock, Andrew M. Ellisdon

J Biol Chem. 2015 Aug 21; 290(34): 20827–20840. Published online 2015 Jun 24. doi: 10.1074/jbc.M115.660456

PMCID:: PMC4543645

Abstract Article PDF–4.0M

Select item 30206214.

The Rab3 GDP/GTP exchange factor homolog AEX-3 has a dual function in synaptic transmission

Kouichi Iwasaki, Rika Toyonaga

EMBO J. 2000 Sep 1; 19(17): 4806–4816. doi: 10.1093/emboj/19.17.4806

PMCID:: PMC302062

Abstract Article PDF–649K

Select item 567960915.

The phosphomimetic mutation of syndecan-4 binds and inhibits Tiam1 modulating Rac1 activity in PDZ interaction–dependent manner

Aniko Keller-Pinter, Bettina Ughy, Monika Domoki, Aladar Pettko-Szandtner, Tamas Letoha, Jozsef Tovari, Jozsef Timar, Laszlo Szilak

PLoS One. 2017; 12(11): e0187094. Published online 2017 Nov 9. doi: 10.1371/journal.pone.0187094

PMCID:: PMC5679609

Abstract Article PDF–2.8M

Select item 285627116.

The Connecdenn Family, Rab35 Guanine Nucleotide Exchange Factors Interfacing with the Clathrin Machinery

Andrea L. Marat, Peter S. McPherson

J Biol Chem. 2010 Apr 2; 285(14): 10627–10637. Published online 2010 Feb 12. doi: 10.1074/jbc.M109.050930

PMCID:: PMC2856271

Abstract Article PDF–4.0M

Select item 543324817.

Altered GABA_A Receptor expression in brainstem Nuclei and SUDEP in Gabrg2^+/Q390X Mice Associated with Epileptic Encephalopathy

Geqing Xia, Sarah Pourali, Timothy A Warner, Chun-Qing Zhang, Robert L. Macdonald, Jing-Qiong Kang

Epilepsy Res. Author manuscript; available in PMC 2017 May 16.

Published in final edited form as: Epilepsy Res. 2016 Jul; 123: 50–54. Published online 2016 Apr 13. doi: 10.1016/j.eplepsyres.2016.04.002

PMCID:: PMC5433248

Abstract Article PDF–808K

Select item 547997118.

Large-scale structural alteration of brain in epileptic children with SCN1A mutation

Yun-Jeong Lee, Mi-Sun Yum, Min-Jee Kim, Woo-Hyun Shim, Hee Mang Yoon, Il Han Yoo, Jiwon Lee, Byung Chan Lim, Ki Joong Kim, Tae-Sung Ko

Neuroimage Clin. 2017; 15: 594–600. Published online 2017 Jun 6. doi: 10.1016/j.nicl.2017.06.002

PMCID:: PMC5479971

Abstract Article PDF–341K

Select item 555409819.

OVEREXPRESSING WILD-TYPE γ2 SUBUNITS RESCUED THE SEIZURE PHENOTYPE IN GABRG2^+/Q390X DRAVET SYNDROME MICE

Xuan Huang, Chengwen Zhou, Mengnan Tian, Jing-Qiong Kang, Wangzhen Shen, Kelienne Verdier, Aurea Pimenta, Robert L Macdonald

Epilepsia. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Epilepsia. 2017 Aug; 58(8): 1451–1461. Published online 2017 Jun 6. doi: 10.1111/epi.13810

PMCID:: PMC5554098

Abstract Article PDF–1.6M

Select item 282074020.

Real-time NMR Study of Guanine Nucleotide Exchange and Activation of RhoA by PDZ-RhoGEF

Geneviève M. C. Gasmi-Seabrook, Christopher B. Marshall, Melissa Cheung, Bryan Kim, Feng Wang, Ying Ju Jang, Tak W. Mak, Vuk Stambolic, Mitsuhiko Ikura

J Biol Chem. 2010 Feb 19; 285(8): 5137–5145. Published online 2009 Dec 17. doi: 10.1074/jbc.M109.064691