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Select item 117240961.

Local translatome sustains synaptic function in impaired Wallerian degeneration

Maria Paglione, Leonardo Restivo, Sarah Zakhia, Arnau Llobet Rosell, Marco Terenzio, Lukas J Neukomm

EMBO Rep. 2025 Jan; 26(1): 61–83. Published online 2024 Oct 31. doi: 10.1038/s44319-024-00301-8

PMCID:: PMC11724096

Abstract Article PDF–4.5M

Select item 117239432.

Machine learning identified novel players in lipid metabolism, endosomal trafficking, and iron metabolism of the ALS spinal cord

Jack Cheng, Bor-Tsang Wu, Hsin-Ping Liu, Wei-Yong Lin

Sci Rep. 2025; 15: 1564. Published online 2025 Jan 10. doi: 10.1038/s41598-024-81315-z

PMCID:: PMC11723943

Abstract Article PDF–3.5M

Select item 117236523.

Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution

Huige Tong, Xiaolong Guo, Macsue Jacques, Qi Luo, Nir Eynon, Andrew E. Teschendorff

Aging (Albany NY) 2024 Dec 31; 16(22): 13452–13504. Published online 2024 Dec 29. doi: 10.18632/aging.206184

PMCID:: PMC11723652

Abstract Article PDF–6.6M

Select item 117227144.

Fatal familial insomnia: Reporting a case of the rare nightmare

E Hogue, D Weinberg, E Palecek

J Postgrad Med. 2024 Oct-Dec; 70(4): 252–254. Published online 2024 Dec 11. doi: 10.4103/jpgm.jpgm_582_24

PMCID:: PMC11722714

Abstract Article

Select item 117221165.

Endoplasmic reticulum stress-related deficits in calcium clearance promote neuronal dysfunction that is prevented by SERCA2 gene augmentation

Yukihiro Shiga, Aline Giselle Rangel Olguin, Sana El Hajji, Nicolas Belforte, Heberto Quintero, Florence Dotigny, Luis Alarcon-Martinez, Arjun Krishnaswamy, Adriana Di Polo

Cell Rep Med. 2024 Dec 17; 5(12): 101839. Published online 2024 Nov 29. doi: 10.1016/j.xcrm.2024.101839

PMCID:: PMC11722116

Abstract Article PDF–9.0M

Select item 117216976.

Flap endonuclease 1 repairs DNA-protein cross-links via ADP-ribosylation–dependent mechanisms

Yilun Sun, Lisa M. Jenkins, Lara H. El Touny, Linying Zhu, Xi Yang, Ukhyun Jo, Lauren Escobedo, Tapan K. Maity, Liton Kumar Saha, Isabel Uribe, Sourav Saha, Shunichi Takeda, Anthony K. L. Leung, Ken Cheng, Yves Pommier

Sci Adv. 2025 Jan 10; 11(2): eads2919. Published online 2025 Jan 10. doi: 10.1126/sciadv.ads2919

PMCID:: PMC11721697

Abstract Article PDF–9.6M

Select item 117216807.

Association of Novel Pathogenic Variant (p. Ile366Asn) in PLA2G6 Gene with Infantile Neuroaxonal Dystrophy

Asma Naseer Cheema, Ruyu Shi, M. Ilyas Kamboh

Int J Mol Sci. 2025 Jan; 26(1): 352. Published online 2025 Jan 3. doi: 10.3390/ijms26010352

PMCID:: PMC11721680

Abstract Article PDF–3.1M

Select item 117202878.

Localization of Melanocortin 1 Receptor in the Substantia Nigra

Ayuka Ehara, Nozomi Ito, Kazuhiko Nakadate, Nobuko Tokuda

Int J Mol Sci. 2025 Jan; 26(1): 236. Published online 2024 Dec 30. doi: 10.3390/ijms26010236

PMCID:: PMC11720287

Abstract Article PDF–9.2M

Select item 117200219.

A Role of Inflammation in Charcot–Marie–Tooth Disorders—In a Perspective of Treatment?

Joanna Kamińska, Andrzej Kochański

Int J Mol Sci. 2025 Jan; 26(1): 15. Published online 2024 Dec 24. doi: 10.3390/ijms26010015

PMCID:: PMC11720021

Abstract Article PDF–710K

Select item 1171952510.

Evolutionarily Developed Alternatively Spliced Exons Containing Translation Initiation Sites

Jun-ichi Takeda, Takaaki Okamoto, Akio Masuda

Cells. 2025 Jan; 14(1): 11. Published online 2024 Dec 26. doi: 10.3390/cells14010011

PMCID:: PMC11719525

Abstract Article PDF–2.3M

Select item 1171910111.

Identification of the m6A/m5C/m1A methylation modification genes in Alzheimer’s disease based on bioinformatic analysis

Qifa Tan, Desheng Zhou, Yuan Guo, Haijun Chen, Peng Xie

Aging (Albany NY) 2024 Nov 30; 16(21): 13340–13355. Published online 2024 Oct 31. doi: 10.18632/aging.206146

PMCID:: PMC11719101

Abstract Article PDF–3.7M

Select item 1171807912.

Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids

Xianwei Chen, Guoqiang Sun, Lizhao Feng, E Tian, Yanhong Shi

Commun Biol. 2025; 8: 30. Published online 2025 Jan 9. doi: 10.1038/s42003-024-07401-0

PMCID:: PMC11718079

Abstract Article PDF–6.9M

Select item 1171787813.

Comparison of the ability of different quantitative indices in ¹²³I-FP-CIT single-photon emission computed tomography to differentiate dopaminergic neurodegenerative disease

Tomohiro Sato, Setsu Sawai, Naokazu Shimada

Jpn J Radiol. 2025; 43(1): 78–90. Published online 2024 Sep 5. doi: 10.1007/s11604-024-01648-7

PMCID:: PMC11717878

Abstract Article PDF–1.0M

Select item 1171627514.

Chemerin-9 is neuroprotective in APP/PS1 transgenic mice by inhibiting NLRP3 inflammasome and promoting microglial clearance of Aβ

Jiawei Zhang, Yaxuan Zhang, Lan Liu, Mengyuan Zhang, Xiaojie Zhang, Jiangshan Deng, Fei Zhao, Qing Lin, Xue Zheng, Bing Fu, Yuwu Zhao, Xiuzhe Wang

J Neuroinflammation. 2025; 22: 5. Published online 2025 Jan 8. doi: 10.1186/s12974-024-03325-y

PMCID:: PMC11716275

Abstract Article PDF–19M

Select item 1171177015.

DNA Damage and Chromatin Rearrangement Work Together to Promote Neurodegeneration

Harman Sharma, Sushma Koirala, Yee Lian Chew, Anna Konopka

Mol Neurobiol. 2025; 62(1): 1282–1290. Published online 2024 Jul 8. doi: 10.1007/s12035-024-04331-0

PMCID:: PMC11711770

Abstract Article PDF–1021K

Select item 1171175516.

Microglia depletion reduces neurodegeneration and remodels extracellular matrix in a mouse Parkinson’s disease model triggered by α-synuclein overexpression

Zhen Zhang, Kun Niu, Taoying Huang, Jiali Guo, Gongbikai Xarbat, Xiaoli Gong, Yunke Gao, Feiyang Liu, Shan Cheng, Wenting Su, Fei Yang, Zhaoyuan Liu, Florent Ginhoux, Ting Zhang

NPJ Parkinsons Dis. 2025; 11: 15. Published online 2025 Jan 9. doi: 10.1038/s41531-024-00846-4

PMCID:: PMC11711755

Abstract Article PDF–4.6M

Select item 1170928517.

Are oligodendrocytes bystanders or drivers of Parkinson’s disease pathology?

José María Salazar Campos, Lena F. Burbulla, Sarah Jäkel

PLoS Biol. 2025 Jan; 23(1): e3002977. Published online 2025 Jan 8. doi: 10.1371/journal.pbio.3002977

PMCID:: PMC11709285

Abstract Article PDF–1.4M

Select item 1170782718.

A-T neurodegeneration and DNA damage-induced transcriptional stress

Tanya T. Paull, Phillip Woolley

DNA Repair (Amst) Author manuscript; available in PMC 2025 Jan 8.

Published in final edited form as: DNA Repair (Amst). 2024 Mar; 135: 103647. Published online 2024 Feb 15. doi: 10.1016/j.dnarep.2024.103647

PMCID:: PMC11707827

Abstract Article PDF–844K

Select item 1170693619.

Identification of blood transcriptome modules associated with suicidal ideation in patients with major depressive disorder

Min Wang, Hailin Xiang, Jinxue Wei, Yikai Dou, Yushun Yan, Yue Du, Huanhuan Fan, Liansheng Zhao, Rongjun Ni, Xiao Yang, Xiaohong Ma

Sci Rep. 2025; 15: 1067. Published online 2025 Jan 7. doi: 10.1038/s41598-025-85431-2

PMCID:: PMC11706936

Abstract Article PDF–2.4M

Select item 1170664220.

Gene expression comparisons between captive and wild shrew brains reveal captivity effects

Maria Alejandra Bedoya Duque, William R. Thomas, Dina K. N. Dechmann, John Nieland, Cecilia Baldoni, Dominik von Elverfeldt, Marion Muturi, Angelique P. Corthals, Liliana M. Dávalos

Biol Lett. 2025 Jan; 21(1): 20240478. Published online January 8, 2025. doi: 10.1098/rsbl.2024.0478