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Select item 97241801.

Morphologic, immunophenotypic, and molecular genetic comparison study in patients with clonal cytopenia of undetermined significance, myelodysplastic syndrome, and acute myeloid leukemia with myelodysplasia-related changes: A single institution experience

Linlin Gao, Stephen Hyter, Da Zhang, Sarah Kelting, Janet Woodroof, Al-Ola Abdallah, Abdulraheem Yacoub, Joseph McGuirk, Haitham Abdelhakim, Andrew K. Godwin, Wei Cui

Int J Lab Hematol. Author manuscript; available in PMC 2022 Dec 6.

Published in final edited form as: Int J Lab Hematol. 2022 Aug; 44(4): 738–749. Published online 2022 Mar 29. doi: 10.1111/ijlh.13840

PMCID:: PMC9724180

Abstract Article PDF–769K

Select item 73182312.

The diagnostic and prognostic role of flow cytometry in idiopathic and clonal cytopenia of undetermined significance (ICUS/CCUS): A single‐center analysis of 79 patients

Konstantinos Dimopoulos, Olga Kristina Hansen, Lene Dissing Sjö, Leonie Saft, Ida Marianne Schjødt, Jakob Werner Hansen, Kirsten Grønbæk

Cytometry B Clin Cytom. 2020 May; 98(3): 250–258. Published online 2019 Sep 3. doi: 10.1002/cyto.b.21842

PMCID:: PMC7318231

Abstract Article PDF–1.9M

Select item 81685013.

Structural aberrations are associated with poor survival in patients with clonal cytopenia of undetermined significance

Stine U. Mikkelsen, Setareh Safavi, Konstantinos Dimopoulos, Colm J. O’Rourke, Mette K. Andersen, Mette S. Holm, Claus W. Marcher, Jesper B. Andersen, Jakob W. Hansen, Kirsten Grønbæk

Haematologica. 2021 Jun 1; 106(6): 1762–1766. Published online 2020 Nov 12. doi: 10.3324/haematol.2020.263319

PMCID:: PMC8168501

Article PDF–564K

Select item 87103744.

Clonal Cytopenia of Undetermined Significance in a Patient with Congenital Wilms' Tumor 1 and Acquired DNMT3A Gene Mutations

Ken Murakami, Yuuta Yamaguchi, Yuko Kida, Yoichiro Morikawa, Hidetoshi Ujiie, Hiroyuki Sugahara, Yasuhito Nannya, Seishi Ogawa, Yuzuru Kanakura

Intern Med. 2021 Dec 1; 60(23): 3785–3788. Published online 2021 May 29. doi: 10.2169/internalmedicine.7571-21

PMCID:: PMC8710374

Abstract Article PDF–304K

Select item 89665455.

Clonal cytopenia of undetermined significance and atypical Behçet’s: the importance of zinc

Patricia Leonard, Alison Louw, David Prentice, Melita Cirillo

BMJ Case Rep. 2022; 15(3): e247154. Published online 2022 Mar 29. doi: 10.1136/bcr-2021-247154

PMCID:: PMC8966545

Abstract Article PDF–745K

Select item 95355196.

Abnormal CD13/HLA-DR Expression Pattern on Myeloblasts Predicts Development of Myeloid Neoplasia in Patients With Clonal Cytopenia of Undetermined Significance

Dragan Jevremovic, Ahmad Nanaa, Susan M Geyer, Michael Timm, Haya Azouz, Cynthia Hengel, Alexander Reberg, Rong He, David Viswanatha, Mohamad E Salama, Min Shi, Horatiu Olteanu, Pedro Horna, Gregory Otteson, Patricia T Greipp, Zhuoer Xie, Hassan B Alkhateeb, William Hogan, Mark Litzow, Mrinal M Patnaik, Mithun Shah, Aref Al-Kali, Phuong L Nguyen

Am J Clin Pathol. 2022 Oct; 158(4): 530–536. Published online 2022 Aug 8. doi: 10.1093/ajcp/aqac083

PMCID:: PMC9535519

Abstract Article PDF–551K

Select item 102243087.

LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

Katja Kaastrup, Linn Gillberg, Stine U. Mikkelsen, Andreas D. Ørskov, Claudia Schöllkopf, Bo K. Mortensen, Bo Porse, Jakob W. Hansen, Kirsten Grønbæk

Clin Epigenetics. 2023; 15: 91. Published online 2023 May 26. doi: 10.1186/s13148-023-01505-w

PMCID:: PMC10224308

Abstract Article PDF–2.5M

Select item 102408398.

Clonal cytopenia of undetermined significance (CCUS)-associated reversion of donor-derived, transient αβ T-cell large granular clonal lymphocytosis, emerging post-transplant in a patient with a history of γδ T-cell large granular lymphocytic leukemia

Siba El Hussein, Andrew G. Evans, John M. Fitzsimmons, Nufatt Leong, Meghan Buldo, Jeremy P. Segal, Audrey N. Jajosky, Paul G. Rothberg, Jane L. Liesveld, Zoltán N. Oltvai

Cold Spring Harb Mol Case Stud. 2023 Apr; 9(2): a006241. doi: 10.1101/mcs.a006241

PMCID:: PMC10240839

Abstract Article PDF–2.3M

Select item 92704759.

Mithun Vinod Shah, Abhishek A. Mangaonkar, Kebede H. Begna, Hassan B. Alkhateeb, Patricia Greipp, Ahmad Nanaa, Michelle A. Elliott, William J. Hogan, Mark R. Litzow, Kristen McCullough, Ayalew Tefferi, Naseema Gangat, Mrinal M. Patnaik, Aref Al-Kali, Rong He, Dong Chen

Blood Cancer J. 2022 Jul; 12(7): 106. Published online 2022 Jul 8. doi: 10.1038/s41408-022-00703-8

PMCID:: PMC9270475

Abstract Article PDF–2.1M

Select item 1137107910.

Clonal Hematopoiesis in Patients With Neuroendocrine Tumor Treated With Lutetium-177 and the Risk of Thrombocytopenia: A Prospective Study

Yael Kusne, Terra Lasho, Christy Finke, Zaid Elsabbagh, Shaylene McCue, Timothy Hobday, Jason Starr, Tanios Bekaii-Saab, Thorvardur R. Halfdanarson, Mrinal M. Patnaik, Fang-Shu Ou, Mohamad Bassam Sonbol

JCO Precis Oncol. 2024; 8: e2400143. Published online 2024 Jul 8. doi: 10.1200/PO.24.00143

PMCID:: PMC11371079

Abstract Article PDF–698K

Select item 736258211.

SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS

Luca Malcovati, Kristen Stevenson, Elli Papaemmanuil, Donna Neuberg, Rafael Bejar, Jacqueline Boultwood, David T. Bowen, Peter J. Campbell, Benjamin L. Ebert, Pierre Fenaux, Torsten Haferlach, Michael Heuser, Joop H. Jansen, Rami S. Komrokji, Jaroslaw P. Maciejewski, Matthew J. Walter, Michaela Fontenay, Guillermo Garcia-Manero, Timothy A. Graubert, Aly Karsan, Manja Meggendorfer, Andrea Pellagatti, David A. Sallman, Michael R. Savona, Mikkael A. Sekeres, David P. Steensma, Sudhir Tauro, Felicitas Thol, Paresh Vyas, Arjan A. Van de Loosdrecht, Detlef Haase, Heinz Tüchler, Peter L. Greenberg, Seishi Ogawa, Eva Hellstrom-Lindberg, Mario Cazzola

Blood. 2020 Jul 9; 136(2): 157–170. Prepublished online 2020 Apr 29. doi: 10.1182/blood.2020004850

Correction in:: Blood. 2021 May 27; 137(21): 3003.

PMCID:: PMC7362582

Abstract Article

Select item 852374712.

TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis

Morten Tulstrup, Mette Soerensen, Jakob Werner Hansen, Linn Gillberg, Maria Needhamsen, Katja Kaastrup, Kristian Helin, Kaare Christensen, Joachim Weischenfeldt, Kirsten Grønbæk

Nat Commun. 2021; 12: 6061. Published online 2021 Oct 18. doi: 10.1038/s41467-021-26093-2

PMCID:: PMC8523747

Abstract Article PDF–1.6M

Select item 916209413.

The diagnostic utility of targeted gene panel sequencing in discriminating etiologies of cytopenia

Gang Zheng, Ping Chen, Aparna Pallavajjalla, Lisa Haley, Lukasz Gondek, Amy Dezern, Hua Ling, Federico De Marchi, Ming-Tseh Lin, Christopher Gocke

Am J Hematol. Author manuscript; available in PMC 2022 Jun 2.

Published in final edited form as: Am J Hematol. 2019 Oct; 94(10): 1141–1148. Published online 2019 Aug 7. doi: 10.1002/ajh.25592

PMCID:: PMC9162094

Abstract Article PDF–814K

Select item 1051430914.

U2AF1 pathogenic variants in myeloid neoplasms and precursor states: distribution of co-mutations and prognostic heterogeneity

Talha Badar, Yenny A. Moreno Vanegas, Ahmad Nanaa, James M. Foran, Aref Al-Kali, Abhishek Mangaonkar, Hemant Murthy, Hassan B. Alkhateeb, David Viswanatha, Rong He, Mithun Shah, Cecilia Arana Yi, Mark R. Litzow, Naseema Gangat, Ayalew Tefferi, Mrinal M. Patnaik

Blood Cancer J. 2023 Dec; 13(1): 149. Published online 2023 Sep 21. doi: 10.1038/s41408-023-00922-7

PMCID:: PMC10514309

Abstract Article PDF–1.2M

Select item 1094588215.

Cancer patients with clonal hematopoiesis die from primary malignancy or comorbidities despite higher rates of transformation to myeloid neoplasms

Kelly S. Chien, Faustine Ong, Kunhwa Kim, Ziyi Li, Rashmi Kanagal‐Shamanna, Courtney D. DiNardo, Koichi Takahashi, Guillermo Montalban‐Bravo, Danielle Hammond, Koji Sasaki, Sherry A. Pierce, Hagop M. Kantarjian, Guillermo Garcia‐Manero

Cancer Med. 2024 Mar; 13(5): e7093. Published online 2024 Mar 18. doi: 10.1002/cam4.7093

PMCID:: PMC10945882

Abstract Article PDF–7.5M

Select item 971210116.

Comparison of the revised 4th (2016) and 5th (2022) editions of the World Health Organization classification of myelodysplastic neoplasms

Yudi Zhang, Junying Wu, Tiejun Qin, Zefeng Xu, Shiqiang Qu, Lijuan Pan, Bing Li, Huijun Wang, Peihong Zhang, Xin Yan, Jingye Gong, Qingyan Gao, Robert Peter Gale, Zhijian Xiao

Leukemia. 2022; 36(12): 2875–2882. Published online 2022 Oct 12. doi: 10.1038/s41375-022-01718-7

PMCID:: PMC9712101

Abstract Article PDF–1.9M

Select item 980886917.

胸骨骨髓细胞形态学在染色体核型正常获得性低增生性骨髓衰竭综合征且患者中的诊断价值

陈佳, 秦铁军, 曲士强, 潘丽娟, 张培红, 李冰, 肖志坚, 徐泽锋

Zhonghua Xue Ye Xue Za Zhi. 2022 Nov; 43(11): 928–933. Chinese. doi: 10.3760/cma.j.issn.0253-2727.2022.11.008

PMCID:: PMC9808869

Abstract Article PDF–3.0M

Select item 1156153618.

Risk prediction for clonal cytopenia: multicenter real-world evidence

Zhuoer Xie, Rami Komrokji, Najla Al Ali, Alexandra Regelson, Susan Geyer, Anand Patel, Caner Saygin, Amer M. Zeidan, Jan Philipp Bewersdorf, Lourdes Mendez, Ashwin Kishtagari, Joshua F. Zeidner, Catherine C. Coombs, Yazan F. Madanat, Stephen Chung, Talha Badar, James Foran, Pinkal Desai, Charlton Tsai, Elizabeth A. Griffiths, Monzr M. Al Malki, Idoroenyi Amanam, Catherine Lai, H. Joachim Deeg, Lionel Ades, Cecilia Arana Yi, Afaf E. G. Osman, Shira Dinner, Yasmin Abaza, Justin Taylor, Namrata Chandhok, Deborah Soong, Andrew M. Brunner, Hetty E. Carraway, Abhay Singh, Chiara Elena, Jacqueline Ferrari, Anna Gallì, Sara Pozzi, Eric Padron, Mrinal M. Patnaik, Luca Malcovati, Michael R. Savona, Aref Al-Kali

Blood. 2024 Nov 7; 144(19): 2033–2044. Published online 2024 Jul 20. doi: 10.1182/blood.2024024756

PMCID:: PMC11561536

Abstract Article

Select item 941000419.

Molecular Pathways in Clonal Hematopoiesis: From the Acquisition of Somatic Mutations to Transformation into Hematologic Neoplasm

Charles Gaulin, Katalin Kelemen, Cecilia Arana Yi

Life (Basel) 2022 Aug; 12(8): 1135. Published online 2022 Jul 28. doi: 10.3390/life12081135

PMCID:: PMC9410004

Abstract Article PDF–737K

Select item 1093600720.

p53 biology and reactivation for improved therapy in MDS and AML

Joanna E. Zawacka

Biomark Res. 2024; 12: 34. Published online 2024 Mar 13. doi: 10.1186/s40364-024-00579-9

PMCID:: PMC10936007

Abstract Article PDF–2.5M

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