PMC Articles for MedGen (Select 1001987) - PMC

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Items: 4

Select item 76613981.

Drug efficacy and toxicity prediction: an innovative application of transcriptomic data

Xuhua Xia

Cell Biol Toxicol. 2020; 36(6): 591–602. Published online 2020 Aug 11. doi: 10.1007/s10565-020-09552-2

PMCID:: PMC7661398

Abstract Article PDF–631K

Select item 73845972.

PHARMACOLOGICAL APPROACHES FOR TARGETING CYSTIC FIBROSIS NONSENSE MUTATIONS

Jyoti Sharma, Kim M. Keeling, Steven M. Rowe

Eur J Med Chem. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Eur J Med Chem. 2020 Aug 15; 200: 112436. Published online 2020 May 21. doi: 10.1016/j.ejmech.2020.112436

PMCID:: PMC7384597

Abstract Article PDF–947K

Select item 57523723.

Nasospheroids permit measurements of CFTR-dependent fluid transport

Jennifer S. Guimbellot, Justin M. Leach, Imron G. Chaudhry, Nancy L. Quinney, Susan E. Boyles, Michael Chua, Inmaculada Aban, Ilona Jaspers, Martina Gentzsch

JCI Insight. 2017 Nov 16; 2(22): e95734. Published online 2017 Nov 16. doi: 10.1172/jci.insight.95734

PMCID:: PMC5752372

Abstract Article PDF–750K

Select item 55824124.

Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue

Steven V Molinski, Saumel Ahmadi, Wan Ip, Hong Ouyang, Adriana Villella, John P Miller, Po‐Shun Lee, Kethika Kulleperuma, Kai Du, Michelle Di Paola, Paul DW Eckford, Onofrio Laselva, Ling Jun Huan, Leigh Wellhauser, Ellen Li, Peter N Ray, Régis Pomès, Theo J Moraes, Tanja Gonska, Felix Ratjen, Christine E Bear

EMBO Mol Med. 2017 Sep; 9(9): 1224–1243. Published online 2017 Jun 30. doi: 10.15252/emmm.201607137