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Items: 1 to 20 of 161

1.
An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation
Chunlin Wang, Maoting Hu, Kunlin Yu, Wuling Liu, Anling Hu, Yi Kuang, Lei Huang, Babu Gajendran, Eldad Zacksenhaus, Xiao Xiao, Yaacov Ben-David
Mol Med Rep. 2024 Jun; 29(6): 107. Published online 2024 Apr 26. doi: 10.3892/mmr.2024.13231
PMCID:
PMC11082641
AbstractArticlePDF–4.3M
2.
Synergistic roles of DYRK1A and GATA1 in trisomy 21 megakaryopoiesis
Ying Ting Sit, Kaoru Takasaki, Hyun Hyung An, Yan Xiao, Christian Hurtz, Peter A. Gearhart, Zhe Zhang, Paul Gadue, Deborah L. French, Stella T. Chou
JCI Insight. 2023 Dec 8; 8(23): e172851. Published online 2023 Oct 31. doi: 10.1172/jci.insight.172851
PMCID:
PMC10895998
AbstractArticlePDF–1.9M
3.
miR-1202 acts as anti-oncomiR in myeloid leukaemia by down-modulating GATA-1S expression
Raffaele Sessa, Silvia Trombetti, Alessandra Lo Bianco, Giovanni Amendola, Rosa Catapano, Elena Cesaro, Fara Petruzziello, Maria D'Armiento, Giuseppe Maria Maruotti, Giuseppe Menna, Paola Izzo, Michela Grosso
Open Biol. 2024 Feb; 14(2): 230319. Published online Feburary 14, 2024. doi: 10.1098/rsob.230319
PMCID:
PMC10864098
AbstractArticlePDF–1.4M
4.
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1
Kim E. Nichols, John D. Crispino, Mortimer Poncz, James G. White, Stuart H. Orkin, John M. Maris, Mitchell J. Weiss
Nat Genet. Author manuscript; available in PMC 2023 Oct 14.
Published in final edited form as: Nat Genet. 2000 Mar; 24(3): 266–270. doi: 10.1038/73480
PMCID:
PMC10576470
AbstractArticlePDF–1.3M
5.
Elucidation of the low-expressing erythroid CR1 phenotype by bioinformatic mining of the GATA1-driven blood-group regulome
Ping Chun Wu, Yan Quan Lee, Mattias Möller, Jill R. Storry, Martin L. Olsson
Nat Commun. 2023; 14: 5001. Published online 2023 Aug 17. doi: 10.1038/s41467-023-40708-w
PMCID:
PMC10435571
AbstractArticlePDF–1.2M
6.
Molecular basis of non-deletional HPFH in Thailand and identification of two novel mutations at the binding sites of CCAAT and GATA-1 transcription factors
Kritsada Singha, Anupong Pansuwan, Mattanee Chewasateanchai, Goonnapa Fucharoen, Supan Fucharoen
Sci Rep. 2023; 13: 11926. Published online 2023 Jul 24. doi: 10.1038/s41598-023-39173-8
PMCID:
PMC10366219
AbstractArticlePDF–1.8M
7.
Multidimensional profiling reveals GATA1-modulated stage-specific chromatin states and functional associations during human erythropoiesis
Dong Li, Xin-Ying Zhao, Shuo Zhou, Qi Hu, Fan Wu, Hsiang-Ying Lee
Nucleic Acids Res. 2023 Jul 21; 51(13): 6634–6653. Published online 2023 May 31. doi: 10.1093/nar/gkad468
PMCID:
PMC10359633
AbstractArticlePDF–5.2M
8.
Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells
Yao-Jen Chang, Steven Lin, Zhi-Fu Kang, Bin-Jon Shen, Wen-Hai Tsai, Wen-Ching Chen, Hsin-Pin Lu, Yu-Lun Su, Shu-Jen Chou, Shu-Yu Lin, Sheng-Wei Lin, Yin-Jung Huang, Hsin-Hui Wang, Ching-Jin Chang
Int J Mol Sci. 2023 Jun; 24(12): 9830. Published online 2023 Jun 6. doi: 10.3390/ijms24129830
PMCID:
PMC10298087
AbstractArticlePDF–4.3M
9.
SATB1 Chromatin Loops Regulate Megakaryocyte/Erythroid Progenitor Expansion by Facilitating HSP70 and GATA1 Induction
Mark C Wilkes, Hee-Don Chae, Vanessa Scanlon, Alma-Martina Cepika, Ethan P Wentworth, Mallika Saxena, Ascia Eskin, Zugen Chen, Bert Glader, Maria Grazia Roncarolo, Stanley F Nelson, Kathleen M Sakamoto
Stem Cells. 2023 Jun; 41(6): 560–569. Published online 2023 Mar 29. doi: 10.1093/stmcls/sxad025
PMCID:
PMC10267687
AbstractArticlePDF–3.5M
10.
Mechanism of KIT gene regulation by GATA1 lacking the N-terminal domain in Down syndrome–related myeloid disorders
Rika Kanezaki, Tsutomu Toki, Kiminori Terui, Tomohiko Sato, Akie Kobayashi, Ko Kudo, Takuya Kamio, Shinya Sasaki, Koji Kawaguchi, Kenichiro Watanabe, Etsuro Ito
Sci Rep. 2022; 12: 20587. Published online 2022 Nov 29. doi: 10.1038/s41598-022-25046-z
PMCID:
PMC9708825
AbstractArticlePDF–2.4M
11.
A Novel GATA1 Variant in the C-Terminal Zinc Finger Compared with the Platelet Phenotype of Patients with A Likely Pathogenic Variant in the N-Terminal Zinc Finger
José M. Bastida, Stefano Malvestiti, Doris Boeckelmann, Verónica Palma-Barqueros, Mira Wolter, María L. Lozano, Hannah Glonnegger, Rocío Benito, Carlo Zaninetti, Felix Sobotta, Freimut H. Schilling, Neil V. Morgan, Kathleen Freson, José Rivera, Barbara Zieger
Cells. 2022 Oct; 11(20): 3223. Published online 2022 Oct 14. doi: 10.3390/cells11203223
PMCID:
PMC9600848
AbstractArticlePDF–2.1M
12.
Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model
Brahim Arkoun, Elie Robert, Fabien Boudia, Stefania Mazzi, Virginie Dufour, Aurélie Siret, Yasmine Mammasse, Zakia Aid, Matthieu Vieira, Aygun Imanci, Marine Aglave, Marie Cambot, Rachel Petermann, Sylvie Souquere, Philippe Rameau, Cyril Catelain, Romain Diot, Gérard Tachdjian, Olivier Hermine, Nathalie Droin, Najet Debili, Isabelle Plo, Sébastien Malinge, Eric Soler, Hana Raslova, Thomas Mercher, William Vainchenker
J Clin Invest. 2022 Jul 15; 132(14): e156290. Published online 2022 Jul 15. doi: 10.1172/JCI156290
PMCID:
PMC9282925
AbstractArticlePDF–4.5M
13.
GATA binding protein 1 recruits histone deacetylase 2 to the promoter region of nuclear receptor binding protein 2 to affect the tumor microenvironment and malignancy of thyroid carcinoma
Mengyuan Li, Hongwei Jiang, Shengjiang Chen, Yujin Ma
Bioengineered. 2022; 13(4): 11336–11357. Published online 2022 May 1. doi: 10.1080/21655979.2022.2068921
PMCID:
PMC9278442
AbstractArticlePDF–14M
14.
Germline GATA1s-generating mutations predispose to leukemia with acquired trisomy 21 and Down syndrome-like phenotype
Henrik Hasle, Ronald M. Kline, Eigil Kjeldsen, Nik F. Nik-Abdul-Rashid, Deepa Bhojwani, Jeffrey M. Verboon, Stephanie P. DiTroia, Katherine R. Chao, Klas Raaschou-Jensen, Josefine Palle, C. Michel Zwaan, Charlotte Guldborg Nyvold, Vijay G. Sankaran, Alan B. Cantor
Blood. 2022 May 26; 139(21): 3159–3165. doi: 10.1182/blood.2021011463
PMCID:
PMC9136882
AbstractArticle
15.
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1
Leif S. Ludwig, Caleb A. Lareau, Erik L. Bao, Nan Liu, Taiju Utsugisawa, Alex M. Tseng, Samuel A. Myers, Jeffrey M. Verboon, Jacob C. Ulirsch, Wendy Luo, Christoph Muus, Claudia Fiorini, Meagan E. Olive, Christopher M. Vockley, Mathias Munschauer, Abigail Hunter, Hiromi Ogura, Toshiyuki Yamamoto, Hiroko Inada, Shinichiro Nakagawa, Shuichi Ohzono, Vidya Subramanian, Roberto Chiarle, Bertil Glader, Steven A. Carr, Martin J. Aryee, Anshul Kundaje, Stuart H. Orkin, Aviv Regev, Timothy L. McCavit, Hitoshi Kanno, Vijay G. Sankaran
Blood. 2022 Apr 21; 139(16): 2534–2546. doi: 10.1182/blood.2021013753
Correction in:
Blood. 2023 Mar 2; 141(9): 1094.
PMCID:
PMC9029090
AbstractArticle
16.
GATA-1 Defects in Diamond–Blackfan Anemia: Phenotypic Characterization Points to a Specific Subset of Disease
Birgit van Dooijeweert, Sima Kheradmand Kia, Niklas Dahl, Odile Fenneteau, Roos Leguit, Edward Nieuwenhuis, Wouter van Solinge, Richard van Wijk, Lydie Da Costa, Marije Bartels
Genes (Basel) 2022 Mar; 13(3): 447. Published online 2022 Feb 28. doi: 10.3390/genes13030447
PMCID:
PMC8949872
AbstractArticlePDF–1.7M
17.
SENP1 promotes triple-negative breast cancer invasion and metastasis via enhancing CSN5 transcription mediated by GATA1 deSUMOylation
Yongchang Gao, Rongrong Wang, Jianjing Liu, Ke Zhao, Xiaolong Qian, Xianghui He, Hong Liu
Int J Biol Sci. 2022; 18(5): 2186–2201. Published online 2022 Mar 6. doi: 10.7150/ijbs.60594
PMCID:
PMC8935229
AbstractArticlePDF–4.2M
18.
Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of GATA1 and STAG2 Mutations in Induced Pluripotent Stem Cells with Trisomy 21
Sonali P. Barwe, Aimy Sebastian, Ishnoor Sidhu, Edward Anders Kolb, Anilkumar Gopalakrishnapillai
Cells. 2022 Feb; 11(4): 628. Published online 2022 Feb 11. doi: 10.3390/cells11040628
PMCID:
PMC8870267
AbstractArticlePDF–1.8M
19.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
20.
Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin
Phillip A. Doerfler, Ruopeng Feng, Yichao Li, Lance E. Palmer, Shaina N. Porter, Henry W. Bell, Merlin Crossley, Shondra M. Pruett-Miller, Yong Cheng, Mitchell J. Weiss
Nat Genet. Author manuscript; available in PMC 2022 Feb 2.
Published in final edited form as: Nat Genet. 2021 Aug; 53(8): 1177–1186. Published online 2021 Aug 2. doi: 10.1038/s41588-021-00904-0
PMCID:
PMC8610173
AbstractArticlePDF–5.3M

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