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Select item 104645341.

RING box protein-1(RBX1), a key component of SCF E3 ligase, induced multiple myeloma cell drug-resistance though suppressing p27

Enfang Bao, Yu Zhou, Song He, Jie Tang, Yunhua He, Mengyuan Zhu, Chun Cheng, Yuchan Wang

Cancer Biol Ther. 2023; 24(1): 2231670. Published online 2023 Aug 28. doi: 10.1080/15384047.2023.2231670

PMCID:: PMC10464534

Abstract Article PDF–6.6M

Select item 94819332.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 91567643.

The Ube2m-Rbx1 neddylation-Cullin-RING-Ligase proteins are essential for the maintenance of Regulatory T cell fitness

Di Wu, Haomin Li, Mingwei Liu, Jun Qin, Yi Sun

Nat Commun. 2022; 13: 3021. Published online 2022 May 31. doi: 10.1038/s41467-022-30707-8

PMCID:: PMC9156764

Abstract Article PDF–7.0M

Select item 85143384.

Structural basis of human transcription–DNA repair coupling

Goran Kokic, Felix R. Wagner, Aleksandar Chernev, Henning Urlaub, Patrick Cramer

Nature. 2021; 598(7880): 368–372. Published online 2021 Sep 15. doi: 10.1038/s41586-021-03906-4

PMCID:: PMC8514338

Abstract Article PDF–17M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 59007746.

Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCF^Fbxw7 in a manner dependent on the kinase GSK-3

Shogo Nakayama, Kanae Yumimoto, Atsuki Kawamura, Keiichi I. Nakayama

J Biol Chem. 2018 Apr 13; 293(15): 5705–5714. Published online 2018 Feb 22. doi: 10.1074/jbc.RA117.000741

PMCID:: PMC5900774

Abstract Article PDF–1.6M

Select item 58717807.

Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice

Buqing Ye, Benyu Liu, Lu Hao, Xiaoxiao Zhu, Liuliu Yang, Shuo Wang, Pengyan Xia, Ying Du, Shu Meng, Guanling Huang, Xiwen Qin, Yanying Wang, Xinlong Yan, Chong Li, Junfeng Hao, Pingping Zhu, Luyun He, Yong Tian, Zusen Fan

Nat Commun. 2018; 9: 1261. Published online 2018 Mar 28. doi: 10.1038/s41467-018-03008-2

PMCID:: PMC5871780

Abstract Article PDF–4.7M

Select item 55894818.

Cytoplasmic E3 ubiquitin ligase CUL9 controls cell proliferation, senescence, apoptosis and genome integrity through p53

Zhijun Li, Yue Xiong

Oncogene. Author manuscript; available in PMC 2017 Nov 8.

Published in final edited form as: Oncogene. 2017 Sep 7; 36(36): 5212–5218. Published online 2017 May 8. doi: 10.1038/onc.2017.141

PMCID:: PMC5589481

Abstract Article PDF–654K

Select item 54581449.

pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4^CRBN ubiquitin ligase

Jian An, Charles M. Ponthier, Ragna Sack, Jan Seebacher, Michael B. Stadler, Katherine A. Donovan, Eric S. Fischer

Nat Commun. 2017; 8: 15398. Published online 2017 May 22. doi: 10.1038/ncomms15398

PMCID:: PMC5458144

Abstract Article PDF–925K

Select item 534152010.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

Select item 501612211.

Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4^CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration

Dolores Del Prete, Richard C. Rice, Anjali M. Rajadhyaksha, Luciano D'Adamio

J Biol Chem. 2016 Aug 12; 291(33): 17209–17227. Published online 2016 Jun 20. doi: 10.1074/jbc.M116.733626

PMCID:: PMC5016122

Abstract Article PDF–1.8M

Select item 417231212.

CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity

Zhijun Li, Xin-Hai Pei, Jun Yan, Feng Yan, Kathryn M. Cappell, Angelique W. Whitehurst, Yue Xiong

Mol Cell. Author manuscript; available in PMC 2015 Jun 5.

Published in final edited form as: Mol Cell. 2014 Jun 5; 54(5): 805–819. Published online 2014 May 1. doi: 10.1016/j.molcel.2014.03.046

PMCID:: PMC4172312

Abstract Article PDF–3.7M

Select item 390557313.

Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I

Rama K. Mallampalli, Leah Kaercher, Courtney Snavely, Roopa Pulijala, Bill B. Chen, Tiffany Coon, Jing Zhao, Marianna Agassandian

Cell Signal. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Cell Signal. 2013 Oct; 25(10): 2047–2059. Published online 2013 May 23. doi: 10.1016/j.cellsig.2013.05.012

PMCID:: PMC3905573

Abstract Article PDF–3.1M

Select item 385151914.

Rbx2 regulates neuronal migration through different Cullin5-RING ligase adaptors

Sergi Simó, Jonathan A. Cooper

Dev Cell. Author manuscript; available in PMC 2014 Nov 25.

Published in final edited form as: Dev Cell. 2013 Nov 25; 27(4): 10.1016/j.devcel.2013.09.022. Published online 2013 Nov 7. doi: 10.1016/j.devcel.2013.09.022

PMCID:: PMC3851519

Abstract Article PDF–6.4M

Select item 383402615.

A new mechanism of RhoA ubiquitination and degradation: Roles of SCF^FBXL19 E3 ligase and Erk2

Jianxin Wei, Rachel K. Mialki, Su Dong, Andrew Khoo, Rama K. Mallampalli, Yutong Zhao, Jing Zhao

Biochim Biophys Acta. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Biochim Biophys Acta. 2013 Dec; 1833(12): 10.1016/j.bbamcr.2013.07.005. Published online 2013 Jul 18. doi: 10.1016/j.bbamcr.2013.07.005

PMCID:: PMC3834026

Abstract Article PDF–392K

Select item 378995016.

F-box and WD Repeat Domain-containing-7 (Fbxw7) Protein Targets Endoplasmic Reticulum-anchored Osteogenic and Chondrogenic Transcriptional Factors for Degradation

Kanae Yumimoto, Masaki Matsumoto, Ichiro Onoyama, Kazunori Imaizumi, Keiichi I. Nakayama

J Biol Chem. 2013 Oct 4; 288(40): 28488–28502. Published online 2013 Aug 16. doi: 10.1074/jbc.M113.465179

PMCID:: PMC3789950

Abstract Article PDF–2.8M

Select item 377626517.

Pleiotropic Effects of the Trichloroethylene-Associated P81S VHL Mutation on Metabolism, Apoptosis, and ATM-Mediated DNA Damage Response

Michelle C. DeSimone, W. Kimryn Rathmell, David W. Threadgill

J Natl Cancer Inst. 2013 Sep 18; 105(18): 1355–1364. Published online 2013 Aug 29. doi: 10.1093/jnci/djt226

PMCID:: PMC3776265

Abstract Article PDF–1.1M

Select item 370890018.

The Role of RING Box Protein 1 in Mouse Oocyte Meiotic Maturation

Lin Zhou, Ye Yang, Juanjuan Zhang, Xuejiang Guo, Ye Bi, Xin Li, Ping Zhang, Junqiang Zhang, Min Lin, Zuomin Zhou, Rong Shen, Xirong Guo, Ran Huo, Xiufeng Ling, Jiahao Sha

PLoS One. 2013; 8(7): e68964. Published online 2013 Jul 11. doi: 10.1371/journal.pone.0068964

PMCID:: PMC3708900

Abstract Article PDF–699K

Select item 357241019.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 343895420.

Endoplasmic Reticulum Stress Induces a Caspase-dependent N-terminal Cleavage of RBX1 Protein in B Cells

Shimon Shteingart, Rivka Hadar, Itamar Cohen, Tommer Ravid, Boaz Tirosh

J Biol Chem. 2012 Sep 7; 287(37): 31223–31232. Published online 2012 Jul 20. doi: 10.1074/jbc.M111.314583

PMCID:: PMC3438954

Abstract Article PDF–1.8M

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