PMC Links for GEO Profiles (Select 98873482) - PMC

Select item 107870671.

EBF2 Links KMT2D‐Mediated H3K4me1 to Suppress Pancreatic Cancer Progression via Upregulating KLLN

Bing Yao, Mengying Xing, Shixin Meng, Shang Li, Jingwan Zhou, Ming Zhang, Chen Yang, Shuang Qu, Yucui Jin, Hongyan Yuan, Ke Zen, Changyan Ma

Adv Sci (Weinh) 2024 Jan; 11(2): 2302037. Published online 2023 Nov 28. doi: 10.1002/advs.202302037

PMCID:: PMC10787067

Abstract Article PDF–18M

Select item 75668812.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 67773293.

MicroRNA-204 may participate in the pathogenesis of hypoxic-ischemic encephalopathy through targeting KLLN

Ronglin Chen, Meixia Wang, Shaopin Fu, Feng Cao, Pengkai Duan, Jiefu Lu

Exp Ther Med. 2019 Nov; 18(5): 3299–3306. Published online 2019 Aug 26. doi: 10.3892/etm.2019.7936

PMCID:: PMC6777329

Abstract Article PDF–2.4M

Select item 61341044.

KLLN-mediated DNA damage-induced apoptosis is associated with regulation of p53 phosphorylation and acetylation in breast cancer cells

Madhav Sankunny, Charis Eng

Cell Death Discov. 2018; 4: 92. Published online 2018 Sep 11. doi: 10.1038/s41420-018-0094-x

Correction in:: Cell Death Discov. 2019; 5: 116.

PMCID:: PMC6134104

Abstract Article PDF–1.4M

Select item 48569625.

Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability

Emily A. Nizialek, Madhav Sankunny, Farshad Niazi, Charis Eng

Nucleic Acids Res. 2016 May 5; 44(8): 3586–3594. Published online 2015 Dec 15. doi: 10.1093/nar/gkv1481

PMCID:: PMC4856962

Abstract Article PDF–3.7M

Select item 46143636.

Cell cycle specific distribution of killin: evidence for negative regulation of both DNA and RNA synthesis

Man Qiao, Dan Luo, Yi Kuang, Haiyan Feng, Guangping Luo, Peng Liang

Cell Cycle. 2015 Jun 15; 14(12): 1823–1829. Published online 2015 May 6. doi: 10.1080/15384101.2015.1038686

PMCID:: PMC4614363

Abstract Article PDF–627K

Select item 46134897.

KLLN epigenotype–phenotype associations in Cowden syndrome

Emily A Nizialek, Jessica L Mester, Vineet K Dhiman, Dominic J Smiraglia, Charis Eng

Eur J Hum Genet. 2015 Oct; 23(11): 1538–1543. Published online 2015 Feb 11. doi: 10.1038/ejhg.2015.8

PMCID:: PMC4613489

Abstract Article PDF–838K

Select item 38581158.

Germline and somatic KLLN alterations in breast cancer dysregulate G2 arrest

Emily A. Nizialek, Charissa Peterson, Jessica L. Mester, Erinn Downes-Kelly, Charis Eng

Hum Mol Genet. 2013 Jun 15; 22(12): 2451–2461. Published online 2013 Feb 27. doi: 10.1093/hmg/ddt097

PMCID:: PMC3858115

Abstract Article PDF–307K

Select item 36781499.

Transcription Factor KLLN Inhibits Tumor Growth by AR Suppression, Induces Apoptosis by TP53/TP73 Stimulation in Prostate Carcinomas, and Correlates With Cellular Differentiation

Yu Wang, Deepa Radhakrishnan, Xin He, Donna M. Peehl, Charis Eng

J Clin Endocrinol Metab. 2013 Mar; 98(3): E586–E594. Published online 2013 Feb 5. doi: 10.1210/jc.2012-3490

PMCID:: PMC3678149

Abstract Article

Select item 365532610.

Germline Epigenetic Regulation of KILLIN in Cowden and Cowden-Like Syndromes

Kristi L. Bennett, Jessica Mester, Charis Eng

JAMA. Author manuscript; available in PMC 2013 May 16.

Published in final edited form as: JAMA. 2010 Dec 22; 304(24): 2724–2731. doi: 10.1001/jama.2010.1877

PMCID:: PMC3655326

Abstract Article PDF–1.4M

Select item 323262611.

Incidence and Clinical Characteristics of Thyroid Cancer in Prospective Series of Individuals with Cowden and Cowden-Like Syndrome Characterized by Germline PTEN, SDH, or KLLN Alterations

Joanne Ngeow, Jessica Mester, Lisa A. Rybicki, Ying Ni, Mira Milas, Charis Eng

J Clin Endocrinol Metab. 2011 Dec; 96(12): E2063–E2071. Published online 2011 Sep 28. doi: 10.1210/jc.2011-1616

PMCID:: PMC3232626

Abstract Article

Select item 311057512.

Germline and somatic DNA methylation and epigenetic regulation of KILLIN in renal cell carcinoma

Kristi L. Bennett, Rebecca Campbell, Shireen Ganapathi, Ming Zhou, Brian Rini, Ram Ganapathi, Hartmut P.H. Neumann, Charis Eng

Genes Chromosomes Cancer. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Genes Chromosomes Cancer. 2011 Aug; 50(8): 654–661. Published online 2011 May 16. doi: 10.1002/gcc.20887

PMCID:: PMC3110575

Abstract Article PDF–266K

Select item 229108013.

Killin is a p53-regulated nuclear inhibitor of DNA synthesis

Yong-jig Cho, Peng Liang

Proc Natl Acad Sci U S A. 2008 Apr 8; 105(14): 5396–5401. Published online 2008 Apr 2. doi: 10.1073/pnas.0705410105

PMCID:: PMC2291080

Abstract Article PDF–734K

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