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Items: 1 to 20 of 234

1.
Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure
Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer
Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y
PMCID:
PMC11447256
AbstractArticlePDF–2.8M
2.
The Janus kinase 1 is critical for pancreatic cancer initiation and progression
Hridaya Shrestha, Patrick D. Rädler, Rayane Dennaoui, Madison N. Wicker, Nirakar Rajbhandari, Yunguang Sun, Amy R. Peck, Kerry Vistisen, Aleata A. Triplett, Rafic Beydoun, Esta Sterneck, Dieter Saur, Hallgeir Rui, Kay-Uwe Wagner
Cell Rep. Author manuscript; available in PMC 2024 Jun 23.
Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114202. Published online 2024 May 10. doi: 10.1016/j.celrep.2024.114202
PMCID:
PMC11194014
AbstractArticlePDF–3.3M
3.
Loss of mutL homolog-1 (MLH1) expression promotes acquisition of oncogenic and inhibitor-resistant point mutations in tyrosine kinases
Lorraine Springuel, Elisabeth Losdyck, Pascale Saussoy, Béatrice Turcq, François-Xavier Mahon, Laurent Knoops, Jean-Christophe Renauld
Cell Mol Life Sci. 2016 Dec; 73(24): 4739–4748. Published online 2016 Jul 19. doi: 10.1007/s00018-016-2310-2
PMCID:
PMC11108519
AbstractArticlePDF–1.2M
4.
Individuals with JAK1 variants are affected by syndromic features encompassing autoimmunity, atopy, colitis, and dermatitis
Michael E. Horesh, Marta Martin-Fernandez, Conor Gruber, Sofija Buta, Tom Le Voyer, Eve Puzenat, Harry Lesmana, Yiming Wu, Ashley Richardson, David Stein, Stephanie Hodeib, Mariam Youssef, Jacob A. Kurowski, Elizabeth Feuille, Luis A. Pedroza, Ramsay L. Fuleihan, Alexandria Haseley, Alain Hovnanian, Pierre Quartier, Jérémie Rosain, Georgina Davis, Daniel Mullan, O’Jay Stewart, Roosheel Patel, Angelica E. Lee, Rebecca Rubinstein, Leyla Ewald, Nikhil Maheshwari, Virginia Rahming, Ivan K. Chinn, James R. Lupski, Jordan S. Orange, Vanessa Sancho-Shimizu, Jean-Laurent Casanova, Noura S. Abul-Husn, Yuval Itan, Joshua D. Milner, Jacinta Bustamante, Dusan Bogunovic
J Exp Med. 2024 Jun 3; 221(6): e20232387. Published online 2024 Apr 2. doi: 10.1084/jem.20232387
Correction in:
J Exp Med. 2024 Jun 3; 221(6): e2023238704302024c.
PMCID:
PMC10986756
AbstractArticlePDF–5.3M
5.
Comparative interactome analysis of α-arrestin families in human and Drosophila
Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam
eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328
PMCID:
PMC10945707
AbstractArticlePDF–2.8M
6.
CD146+CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway
Zhicheng Yu, Qian Zhang, Sitian Wei, Yang Zhang, Ting Zhou, Qi Zhang, Rui Shi, Dmitry Zinovkin, Zahidul Islam Pranjol, Jun Zhang, Hongbo Wang
Cell Commun Signal. 2024; 22: 170. Published online 2024 Mar 8. doi: 10.1186/s12964-024-01550-9
PMCID:
PMC10921754
AbstractArticlePDF–12M
7.
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma
Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn
Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255
PMCID:
PMC10916866
AbstractArticlePDF–4.7M
8.
Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway
Bisheng Cheng, Lingfeng Li, Tianlong Luo, Qiong Wang, Yong Luo, Shoumin Bai, Kaiwen Li, Yiming Lai, Hai Huang
J Exp Clin Cancer Res. 2024; 43: 67. Published online 2024 Mar 1. doi: 10.1186/s13046-024-02962-8
Correction in:
J Exp Clin Cancer Res. 2024; 43: 333.
PMCID:
PMC10905933
AbstractArticlePDF–9.6M
9.
WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling
Qingling Huang, Yi Xiao, Ting Lan, Youguang Lu, Li Huang, Dali Zheng
Int J Oral Sci. 2024; 16: 7. Published online 2024 Jan 22. doi: 10.1038/s41368-024-00279-y
PMCID:
PMC10800352
AbstractArticlePDF–4.2M
10.
METTL3 promotes colorectal cancer progression through activating JAK1/STAT3 signaling pathway
Yuechao Sun, Weipeng Gong, Song Zhang
Cell Death Dis. 2023 Nov; 14(11): 765. Published online 2023 Nov 25. doi: 10.1038/s41419-023-06287-w
PMCID:
PMC10673931
AbstractArticlePDF–6.5M
11.
Case control study: G-allele of rs4244165 in JAK1 gene correlated with high-level brief psychiatric rating scale in bipolar patients
Akila Ahlem Elouaer Benkortbi Elouaer, Bochra Ben Mohamed, Ferid Zaafrane, Lotfi Gaha, Besma Bel Hadj Jrad Tensaout
Medicine (Baltimore) 2023 Sep 15; 102(37): e34652. Published online 2023 Sep 15. doi: 10.1097/MD.0000000000034652
PMCID:
PMC10508567
AbstractArticlePDF–529K
12.
The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4
Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang
Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5
PMCID:
PMC10460732
AbstractArticlePDF–5.6M
13.
Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection
Kristen Zarrella, Pierce Longmire, Sebastian Zeltzer, Donna Collins-McMillen, Meaghan Hancock, Jason Buehler, Justin M. Reitsma, Scott S. Terhune, Jay A. Nelson, Felicia Goodrum
PLoS Pathog. 2023 Jun; 19(6): e1011185. Published online 2023 Jun 8. doi: 10.1371/journal.ppat.1011185
PMCID:
PMC10284425
AbstractArticlePDF–3.3M
14.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
15.
TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN
Kaini Zhang, Chen Yang, Xin Zhou, Jin Liang, Jianjin Guo, Min Li, Yi Zhang, Shulin Shao, Peng Sun, Kai Li, Jingjing Huang, Fang Chen, Xiubin Liang, Dongming Su
Cell Mol Life Sci. 2023 Jun; 80(6): 168. Published online 2023 May 30. doi: 10.1007/s00018-023-04820-w
PMCID:
PMC10229743
AbstractArticlePDF–2.9M
16.
EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1
Yihui Pan, Guannan Shu, Liangmin Fu, Kangbo Huang, Xinwei Zhou, Chengpeng Gui, Huashan Liu, Xiaohan Jin, Minyu Chen, Pengju Li, Junjie Cen, Zihao Feng, Jun Lu, Zhenhua Chen, Jiaying Li, Quanhui Xu, Yinghan Wang, Hui Liang, Zhu Wang, Qiong Deng, Wei Chen, Junhang Luo, Jiefeng Yang, Jiaxing Zhang, Jinhuan Wei
Adv Sci (Weinh) 2023 Apr; 10(11): 2206792. Published online 2023 Feb 12. doi: 10.1002/advs.202206792
PMCID:
PMC10104659
AbstractArticlePDF–7.7M
17.
JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling
Alice H. Grant, Alejandro C. Rodriguez, Omar J. Rodriguez Moncivais, Shengjie Sun, Lin Li, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez
Int J Mol Sci. 2023 Apr; 24(7): 6805. Published online 2023 Apr 6. doi: 10.3390/ijms24076805
PMCID:
PMC10095075
AbstractArticlePDF–6.0M
18.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
19.
KIF15 is essential for USP10-mediated PGK1 deubiquitination during the glycolysis of pancreatic cancer
Gang Quan, Jian Xu, Jie Wang, Xinyuan Liu, Jichuan Xu, Jianxin Jiang
Cell Death Dis. 2023 Feb; 14(2): 137. Published online 2023 Feb 17. doi: 10.1038/s41419-023-05679-2
PMCID:
PMC9938189
AbstractArticlePDF–8.4M
20.
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke
Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188
PMCID:
PMC9881136
AbstractArticlePDF–4.4M

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