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Select item 108350431.

Dancr-BRG1 regulates Nfatc1 transcription and Pgc1β-dependent metabolic shifts in osteoclastogenesis

Zheng Zhang, Yichen Meng, Tao Lin, Zhanrong Zhang, Zhengbo Tao, Haozan Yin, Fu Yang, Xuhui Zhou

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2313656121. Published online 2024 Jan 22. doi: 10.1073/pnas.2313656121

PMCID:: PMC10835043

Abstract Article PDF–13M

Select item 107862822.

A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation

Yohei Abe, Eric R. Kofman, Zhengyu Ouyang, Grisel Cruz-Becerra, Nathanael J. Spann, Jason S. Seidman, Ty D. Troutman, Joshua D. Stender, Havilah Taylor, Weiwei Fan, Verena M. Link, Zeyang Shen, Juro Sakai, Michael Downes, Ronald M. Evans, James T. Kadonaga, Michael G. Rosenfeld, Christopher K. Glass

Proc Natl Acad Sci U S A. 2024 Jan 9; 121(2): e2316104121. Published online 2024 Jan 2. doi: 10.1073/pnas.2316104121

PMCID:: PMC10786282

Abstract Article PDF–1.6M

Select item 99867423.

Hacd2 deficiency in mice leads to an early and lethal mitochondrial disease

Nahed Khadhraoui, Alexandre Prola, Aymeline Vandestienne, Jordan Blondelle, Laurent Guillaud, Guillaume Courtin, Maxime Bodak, Bastien Prost, Hélène Huet, Mélody Wintrebert, Christine Péchoux, Audrey Solgadi, Frédéric Relaix, Laurent Tiret, Fanny Pilot-Storck

Mol Metab. 2023 Mar; 69: 101677. Published online 2023 Jan 21. doi: 10.1016/j.molmet.2023.101677

PMCID:: PMC9986742

Abstract Article PDF–3.1M

Select item 97239184.

PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds

Svenia Schmid, Barbara Heim-Kupr, Joaquín Pérez-Schindler, Shivani Mansingh, Markus Beer, Nitish Mittal, Nikolaus Ehrenfeuchter, Christoph Handschin

Mol Metab. 2022 Dec; 66: 101643. Published online 2022 Nov 16. doi: 10.1016/j.molmet.2022.101643

PMCID:: PMC9723918

Abstract Article PDF–4.5M

Select item 90665135.

Adipose tissue-specific ablation of PGC-1β impairs thermogenesis in brown fat

Jiří Funda, Josep A. Villena, Kristina Bardova, Katerina Adamcova, Illaria Irodenko, Pavel Flachs, Ivana Jedlickova, Eliska Haasova, Martin Rossmeisl, Jan Kopecky, Petra Janovska

Dis Model Mech. 2022 Apr 1; 15(4): dmm049223. Published online 2022 Apr 25. doi: 10.1242/dmm.049223

PMCID:: PMC9066513

Abstract Article

Select item 89888696.

Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse

Tatiana L Fonseca, Samuel C Russo, Cristina Luongo, Domenico Salvatore, Antonio C Bianco

Endocrinology. 2022 May; 163(5): bqac026. Published online 2022 Mar 3. doi: 10.1210/endocr/bqac026

PMCID:: PMC8988869

Abstract Article

Select item 82141967.

Perm1 promotes cardiomyocyte mitochondrial biogenesis and protects against hypoxia/reoxygenation-induced damage in mice

Yoshitake Cho, Shizuko Tachibana, Kayla Lam, Yoh Arita, Shamim Khosrowjerdi, Oliver Zhang, Alex Liang, Ruixia Li, Aleksander Andreyev, Anne N. Murphy, Robert S. Ross

J Biol Chem. 2021 Jul; 297(1): 100825. Published online 2021 May 23. doi: 10.1016/j.jbc.2021.100825

Correction in:: J Biol Chem. 2021 Sep; 297(3): 101121.

PMCID:: PMC8214196

Abstract Article PDF–3.3M

Select item 81090818.

Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis

Hui Zhang, Aifei Wang, Guangsi Shen, Xiao Wang, Gongwen Liu, Fan Yang, Bin Chen, Mingyong Wang, Youjia Xu

Aging (Albany NY) 2021 Apr 30; 13(8): 11296–11314. Published online 2021 Apr 4. doi: 10.18632/aging.202817

PMCID:: PMC8109081

Abstract Article PDF–2.2M

Select item 80919689.

Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues

Keiichi Ito, Marc Schneeberger, Alan Gerber, Miki Jishage, Francois Marchildon, Aarthi V. Maganti, Paul Cohen, Jeffrey M. Friedman, Robert G. Roeder

Genes Dev. 2021 May 1; 35(9-10): 729–748. doi: 10.1101/gad.346791.120

PMCID:: PMC8091968

Abstract Article PDF–13M

Select item 795503510.

PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2

Sean A. Murphy, Matthew Miyamoto, Anaïs Kervadec, Suraj Kannan, Emmanouil Tampakakis, Sandeep Kambhampati, Brian Leei Lin, Sam Paek, Peter Andersen, Dong-Ik Lee, Renjun Zhu, Steven S. An, David A. Kass, Hideki Uosaki, Alexandre R. Colas, Chulan Kwon

Nat Commun. 2021; 12: 1648. Published online 2021 Mar 12. doi: 10.1038/s41467-021-21957-z

PMCID:: PMC7955035

Abstract Article PDF–2.4M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 756787612.

PGC-1β-expressing POMC neurons mediate the effect of leptin on thermoregulation in the mouse

Julien Delezie, Jonathan F. Gill, Gesa Santos, Bettina Karrer-Cardel, Christoph Handschin

Sci Rep. 2020; 10: 16888. Published online 2020 Oct 15. doi: 10.1038/s41598-020-73794-7

PMCID:: PMC7567876

Abstract Article PDF–3.3M

Select item 739335113.

Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis

Yi Yao, Queping Liu, Indra Adrianto, Xiaojun Wu, James Glassbrook, Namir Khalasawi, Congcong Yin, Qijun Yi, Zheng Dong, Frederic Geissmann, Li Zhou, Qing-Sheng Mi

Nat Commun. 2020; 11: 3822. Published online 2020 Jul 30. doi: 10.1038/s41467-020-17630-6

PMCID:: PMC7393351

Abstract Article PDF–2.9M

Select item 732790514.

FOXO1 suppresses PGC‐1β gene expression in skeletal muscles

Shiho Nakai, Mamoru Oyabu, Yukino Hatazawa, Shiori Akashi, Tadahiro Kitamura, Shinji Miura, Yasutomi Kamei

FEBS Open Bio. 2020 Jul; 10(7): 1373–1388. Published online 2020 Jul 1. doi: 10.1002/2211-5463.12898

PMCID:: PMC7327905

Abstract Article PDF–791K

Select item 730827715.

Dual targeting of SREBP2 and ERRα by carnosic acid suppresses RANKL-mediated osteoclastogenesis and prevents ovariectomy-induced bone loss

Zu-Guo Zheng, Hui-Min Cheng, Ya-Ping Zhou, Si-Tong Zhu, Pyone Myat Thu, Hui-Jun Li, Ping Li, Xiaojun Xu

Cell Death Differ. 2020 Jul; 27(7): 2048–2065. Published online 2020 Jan 6. doi: 10.1038/s41418-019-0484-5

PMCID:: PMC7308277

Abstract Article PDF–7.5M

Select item 710685216.

Slc25a17 Gene Trapped Mice: PMP34 Plays a Role in the Peroxisomal Degradation of Phytanic and Pristanic Acid

Paul P. Van Veldhoven, Evelyn de Schryver, Stephen G. Young, An Zwijsen, Marc Fransen, Marc Espeel, Myriam Baes, Elke Van Ael

Front Cell Dev Biol. 2020; 8: 144. Published online 2020 Mar 24. doi: 10.3389/fcell.2020.00144

PMCID:: PMC7106852

Abstract Article PDF–4.7M

Select item 691115717.

Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction

Charlotte E. Edling, Ibrahim T. Fazmin, Khalil Saadeh, Karan R. Chadda, Shiraz Ahmad, Haseeb Valli, Christopher L.-H. Huang, Kamalan Jeevaratnam

Biosci Rep. 2019 Dec 20; 39(12): BSR20190403. Published online 2019 Dec 13. doi: 10.1042/BSR20190403

PMCID:: PMC6911157

Abstract Article PDF–1.1M

Select item 685616018.

PGC-1β Induces Susceptibility To Acetaminophen-Driven Acute Liver Failure

Elena Piccinin, Simon Ducheix, Claudia Peres, Maria Arconzo, Maria Carmela Vegliante, Anna Ferretta, Elena Bellafante, Gaetano Villani, Antonio Moschetta

Sci Rep. 2019; 9: 16821. Published online 2019 Nov 14. doi: 10.1038/s41598-019-53015-6

PMCID:: PMC6856160

Abstract Article PDF–1.8M

Select item 674812719.

A novel long noncoding RNA PGC1β-OT1 regulates adipocyte and osteoblast differentiation through antagonizing miR-148a-3p

Hairui Yuan, Xiaowei Xu, Xue Feng, Endong Zhu, Jie Zhou, Guannan Wang, Lijie Tian, Baoli Wang

Cell Death Differ. 2019 Oct; 26(10): 2029–2045. Published online 2019 Feb 6. doi: 10.1038/s41418-019-0296-7

PMCID:: PMC6748127

Abstract Article PDF–5.9M

Select item 652628420.

Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration

Mariana Aparecida Brunini Rosales, Daisy Y Shu, Jared Iacovelli, Magali Saint-Geniez

Life Sci Alliance. 2019 Jun; 2(3): e201800212. Published online 2019 May 17. doi: 10.26508/lsa.201800212

Correction in:: Life Sci Alliance. 2019 Jun; 2(3): e201900436.

PMCID:: PMC6526284

Abstract Article PDF–3.8M

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