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Select item 107922471.

Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart

Abhishek Mishra, Mahtab Tavasoli, Stanislav Sokolenko, Christopher R. McMaster, Kishore B.S. Pasumarthi

iScience. 2024 Jan 19; 27(1): 108748. Published online 2023 Dec 14. doi: 10.1016/j.isci.2023.108748

PMCID:: PMC10792247

Abstract Article PDF–9.2M

Select item 96038602.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 85529713.

Conditional Knockout of Pdha1 in Mouse Hippocampus Impairs Cognitive Function: The Possible Involvement of Lactate

Wanxin Chen, Xiaoxia Sun, Libin Zhan, Wen Zhou, Tingting Bi

Front Neurosci. 2021; 15: 767560. Published online 2021 Oct 14. doi: 10.3389/fnins.2021.767560

PMCID:: PMC8552971

Abstract Article PDF–5.5M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 77850545.

Reprogramming of aerobic glycolysis in non‐transformed mouse liver with pyruvate dehydrogenase complex deficiency

Mulchand S. Patel, Saleh Mahmood, Jiwon Jung, Todd C. Rideout

Physiol Rep. 2021 Jan; 9(1): e14684. Published online 2021 Jan 5. doi: 10.14814/phy2.14684

Correction in:: Physiol Rep. 2021 Mar; 9(5): e14793.

PMCID:: PMC7785054

Abstract Article PDF–1.2M

Select item 75347356.

Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis

Zhen Cai, Chien-Feng Li, Fei Han, Chunfang Liu, Anmei Zhang, Che-Chia Hsu, Danni Peng, Xian Zhang, Guoxiang Jin, Abdol-Hossein Rezaeian, Guihua Wang, Weina Zhang, Bo-Syong Pan, Chi-Yun Wang, Yu-Hui Wang, Shih-Ying Wu, Shun-Chin Yang, Fang-Chi Hsu, Ralph B. D’Agostino, Jr., Christina M. Furdui, Gregory L. Kucera, John S. Parks, Floyd H. Chilton, Chih-Yang Huang, Fuu-Jen Tsai, Boris Pasche, Kounosuke Watabe, Hui-Kuan Lin

Mol Cell. 2020 Oct 15; 80(2): 263–278.e7. Published online 2020 Oct 5. doi: 10.1016/j.molcel.2020.09.018

PMCID:: PMC7534735

Abstract Article PDF–7.1M

Select item 70577767.

Conditional knockout of pyruvate dehydrogenase in mouse pancreatic β-cells causes morphological and functional changes

Xiao Wang, Shuchang Lai, Yanshi Ye, Yuanyuan Hu, Daoyan Pan, Xiaochun Bai, Jie Shen

Mol Med Rep. 2020 Apr; 21(4): 1717–1726. Published online 2020 Feb 20. doi: 10.3892/mmr.2020.10993

PMCID:: PMC7057776

Abstract Article PDF–1.3M

Select item 66923358.

Sirtuin 3-mediated pyruvate dehydrogenase activity determines brown adipocytes phenotype under high-salt conditions

Tong Wei, Gaojian Huang, Penghao Liu, Jing Gao, Chenglin Huang, Mengwei Sun, Weili Shen

Cell Death Dis. 2019 Aug; 10(8): 614. Published online 2019 Aug 14. doi: 10.1038/s41419-019-1834-4

PMCID:: PMC6692335

Abstract Article PDF–3.3M

Select item 63139009.

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II

Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053

Correction in:: Proteomes. 2019 Mar; 7(1): 7.

PMCID:: PMC6313900

Abstract Article PDF–2.5M

Select item 629804010.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 629317011.

Defining the contribution of skeletal muscle pyruvate dehydrogenase α1 to exercise performance and insulin action

Kristoffer Svensson, Jessica R. Dent, Shahriar Tahvilian, Vitor F. Martins, Abha Sathe, Julien Ochala, Mulchand S. Patel, Simon Schenk

Am J Physiol Endocrinol Metab. 2018 Nov 1; 315(5): E1034–E1045. Published online 2018 Aug 28. doi: 10.1152/ajpendo.00241.2018

PMCID:: PMC6293170

Abstract Article

Select item 584564612.

Cardiac-Specific Deletion of Pyruvate Dehydrogenase Impairs Glucose Oxidation Rates and Induces Diastolic Dysfunction

Keshav Gopal, Malak Almutairi, Rami Al Batran, Farah Eaton, Manoj Gandhi, John Reyes Ussher

Front Cardiovasc Med. 2018; 5: 17. Published online 2018 Mar 6. doi: 10.3389/fcvm.2018.00017

PMCID:: PMC5845646

Abstract Article PDF–1.6M

Select item 581091213.

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer

Jingjing Chen, Ilaria Guccini, Diletta Di Mitri, Daniela Brina, Ajinkya Revandkar, Manuela Sarti, Emiliano Pasquini, Abdullah Alajati, Sandra Pinton, Marco Losa, Gianluca Civenni, Carlo V. Catapano, Jacopo Sgrignani, Andrea Cavalli, Rocco D'Antuono, John M. Asara, Andrea Morandi, Paola Chiarugi, Sara Crotti, Marco Agostini, Monica Montopoli, Ionica Masgras, Andrea Rasola, Ramon Garcia-Escudero, Nicolas Delaleu, Andrea Rinaldi, Francesco Bertoni, Johann de Bono, Arkaitz Carracedo, Andrea Alimonti

Nat Genet. Author manuscript; available in PMC 2018 Jul 15.

Published in final edited form as: Nat Genet. 2018 Feb; 50(2): 219–228. Published online 2018 Jan 15. doi: 10.1038/s41588-017-0026-3

PMCID:: PMC5810912

Abstract Article PDF–1.9M

Select item 577347214.

Characterization of the impact of glutaredoxin-2 (GRX2) deficiency on superoxide/hydrogen peroxide release from cardiac and liver mitochondria

Julia Chalker, Danielle Gardiner, Nidhi Kuksal, Ryan J. Mailloux

Redox Biol. 2018 May; 15: 216–227. Published online 2017 Dec 14. doi: 10.1016/j.redox.2017.12.006

PMCID:: PMC5773472

Abstract Article PDF–1.3M

Select item 574645515.

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals Molecular Determinants of Redox Homeostasis and NF-κB Signaling

Ramy H. Malty, Hiroyuki Aoki, Ashwani Kumar, Sadhna Phanse, Shahreen Amin, Qingzhou Zhang, Zoran Minic, Florian Goebels, Gabriel Musso, Zhuoran Wu, Hosam Abou-tok, Michael Meyer, Viktor Deineko, Sandy Kassir, Vishaldeep Sidhu, Matthew Jessulat, Nichollas E. Scott, Xuejian Xiong, James Vlasblom, Bhanu Prasad, Leonard J. Foster, Tiziana Alberio, Barbara Garavaglia, Haiyuan Yu, Gary D. Bader, Ken Nakamura, John Parkinson, Mohan Babu

Cell Syst. Author manuscript; available in PMC 2018 Dec 27.

Published in final edited form as: Cell Syst. 2017 Dec 27; 5(6): 564–577.e12. Published online 2017 Nov 8. doi: 10.1016/j.cels.2017.10.010

PMCID:: PMC5746455

Abstract Article PDF–3.3M

Select item 566814516.

Genetic dissociation of glycolysis and the TCA cycle affects neither normal nor neoplastic proliferation

Laura E. Jackson, Sucheta Kulkarni, Huabo Wang, Jie Lu, James M. Dolezal, Sivakama S. Bharathi, Sarangarajan Ranganathan, Mulchand S. Patel, Rahul Deshpande, Frances Alencastro, Stacy G. Wendell, Eric S. Goetzman, Andrew W. Duncan, Edward V. Prochownik

Cancer Res. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Cancer Res. 2017 Nov 1; 77(21): 5795–5807. Published online 2017 Sep 7. doi: 10.1158/0008-5472.CAN-17-1325

Correction in:: Cancer Res. 2022 Mar 1; 82(5): 944.

PMCID:: PMC5668145

Abstract Article PDF–823K

Select item 556151917.

Acetyl-CoA production from pyruvate is not necessary for preservation of myelin

Gustavo Della-Flora Nunes, Lauren Mueller, Nicholas Silvestri, Mulchand S Patel, Lawrence Wrabetz, M Laura Feltri, Yannick Poitelon

Glia. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Glia. 2017 Oct; 65(10): 1626–1639. Published online 2017 Jun 28. doi: 10.1002/glia.23184

PMCID:: PMC5561519

Abstract Article PDF–1.2M

Select item 538031018.

Novel insights into SLC25A46-related pathologies in a genetic mouse model

Maria Eirini Terzenidou, Aikaterini Segklia, Toshimi Kano, Florentia Papastefanaki, Alexandros Karakostas, Maria Charalambous, Fotis Ioakeimidis, Maria Papadaki, Ismini Kloukina, Margarita Chrysanthou-Piterou, Martina Samiotaki, George Panayotou, Rebecca Matsas, Eleni Douni

PLoS Genet. 2017 Apr; 13(4): e1006656. Published online 2017 Apr 4. doi: 10.1371/journal.pgen.1006656

PMCID:: PMC5380310

Abstract Article PDF–4.6M

Select item 535051219.

CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs

Désirée Schatton, David Pla-Martin, Marie-Charlotte Marx, Henriette Hansen, Arnaud Mourier, Ivan Nemazanyy, Alberto Pessia, Peter Zentis, Teresa Corona, Vangelis Kondylis, Esther Barth, Astrid C. Schauss, Vidya Velagapudi, Elena I. Rugarli

J Cell Biol. 2017 Mar 6; 216(3): 675–693. doi: 10.1083/jcb.201607019

PMCID:: PMC5350512

Abstract Article PDF–3.2M

Select item 534152020.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

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