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Select item 81841271.

Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses

Adewunmi Adelaja, Brooks Taylor, Katherine M. Sheu, Yi Liu, Stefanie Luecke, Alexander Hoffmann

Immunity. Author manuscript; available in PMC 2021 Jun 7.

Published in final edited form as: Immunity. 2021 May 11; 54(5): 916–930.e7. doi: 10.1016/j.immuni.2021.04.011

PMCID:: PMC8184127

Abstract Article PDF–3.0M

Select item 72716492.

IκBα deficiency imposes a fetal phenotype to intestinal stem cells

Laura Marruecos, Joan Bertran, Yolanda Guillén, Jéssica González, Raquel Batlle, Erika López‐Arribillaga, Marta Garrido, Cristina Ruiz‐Herguido, Dominique Lisiero, Mónica González‐Farré, Sara Arce‐Gallego, Mar Iglesias, Angel R Nebreda, Shigeki Miyamoto, Anna Bigas, Lluís Espinosa

EMBO Rep. 2020 Jun 4; 21(6): e49708. Published online 2020 Apr 9. doi: 10.15252/embr.201949708

PMCID:: PMC7271649

Abstract Article PDF–12M

Select item 71606593.

CpG‐ODN‐mediated TLR9 innate immune signalling and calcium dyshomeostasis converge on the NFκB inhibitory protein IκBβ to drive IL1α and IL1β expression

Robyn De Dios, Leanna Nguyen, Sankar Ghosh, Sarah McKenna, Clyde J. Wright

Immunology. 2020 May; 160(1): 64–77. Published online 2020 Mar 18. doi: 10.1111/imm.13182

PMCID:: PMC7160659

Abstract Article PDF–1.8M

Select item 47309154.

Endotoxemia induces IκBβ/NFκB dependent ET-1 expression in hepatic macrophages

Sarah McKenna, Megan Gossling, Alejandro Bugarini, Elizabeth Hill, Aimee L. Anderson, Raymond C. Rancourt, Natarajan Balasubramaniyan, Karim C. El Kasmi, Clyde J. Wright

J Immunol. Author manuscript; available in PMC 2016 Oct 15.

Published in final edited form as: J Immunol. 2015 Oct 15; 195(8): 3866–3879. Published online 2015 Sep 4. doi: 10.4049/jimmunol.1501017

PMCID:: PMC4730915

Abstract Article PDF–2.0M

Select item 45971445.

Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis

Bo Zheng, Dan Zhao, Pan Zhang, Cong Shen, Yueshuai Guo, Tao Zhou, Xuejiang Guo, Zuomin Zhou, Jiahao Sha

Mol Cell Proteomics. 2015 Oct; 14(10): 2682–2691. Published online 2015 Jul 21. doi: 10.1074/mcp.M115.049569

PMCID:: PMC4597144

Abstract Article PDF–3.8M

Select item 44252316.

I?Bß enhances the generation of the low-affinity NF?B/RelA homodimer

Rachel Tsui, Jeffrey D. Kearns, Candace Lynch, Don Vu, Kim Ngo, Soumen Basak, Gourisankar Ghosh, Alexander Hoffmann

Nat Commun. Author manuscript; available in PMC 2015 Nov 7.

Published in final edited form as: Nat Commun. 2015; 6: 7068. Published online 2015 May 7. doi: 10.1038/ncomms8068

PMCID:: PMC4425231

Abstract Article PDF–2.1M

Select item 44092637.

Targeted Disruption of Ig-Hepta/Gpr116 Causes Emphysema-like Symptoms That Are Associated with Alveolar Macrophage Activation

Donna Maretta Ariestanti, Hikaru Ando, Shigehisa Hirose, Nobuhiro Nakamura

J Biol Chem. 2015 Apr 24; 290(17): 11032–11040. Published online 2015 Mar 16. doi: 10.1074/jbc.M115.648311

PMCID:: PMC4409263

Abstract Article PDF–1.2M

Select item 41774578.

κB-Ras proteins regulate both NF-κB-dependent inflammation and Ral-dependent proliferation

Andrea Oeckinghaus, Thomas S. Postler, Ping Rao, Heike Schmitt, Verena Schmitt, Yenkel Grinberg-Bleyer, Lars I. Kühn, Christian W. Gruber, Gustav E. Lienhard, Sankar Ghosh

Cell Rep. Author manuscript; available in PMC 2015 Sep 25.

Published in final edited form as: Cell Rep. 2014 Sep 25; 8(6): 1793–1807. Published online 2014 Sep 15. doi: 10.1016/j.celrep.2014.08.015

PMCID:: PMC4177457

Abstract Article PDF–1.1M

Select item 39309559.

IκBβ-Mediated NF-κB Activation Confers Protection against Hyperoxic Lung Injury

Katherine A. Michaelis, Fadeke Agboke, Thanh Liu, Kristie Han, Manasa Muthu, Csaba Galambos, Guang Yang, Phyllis A. Dennery, Clyde J. Wright

Am J Respir Cell Mol Biol. 2014 Feb; 50(2): 429–438. doi: 10.1165/rcmb.2013-0303OC

PMCID:: PMC3930955

Abstract Article PDF–1.2M

Select item 370748710.

Nuclear Factor Kappa B Signaling Initiates Early Differentiation of Neural Stem Cells

Yonggang Zhang, Jianjun Liu, Shaohua Yao, Fang Li, Lin Xin, Mowen Lai, Valerie Bracchi-Ricard, Hong Xu, William Yen, Wentong Meng, Shu Liu, Leiting Yang, Shaffiat Karmally, Jin Liu, Hongyan Zhu, Jennifer Gordon, Kamel Khalili, Shanthi Srinivasan, John R. Bethea, Xianming Mo, Wenhui Hu

Stem Cells. Author manuscript; available in PMC 2013 Jul 10.

Published in final edited form as: Stem Cells. 2012 Mar; 30(3): 510–524. doi: 10.1002/stem.1006

PMCID:: PMC3707487

Abstract Article PDF–6.7M

Select item 330728111.

Nuclear Factor-κB (NF-κB) Inhibitory Protein IκBβ Determines Apoptotic Cell Death following Exposure to Oxidative Stress

Clyde J. Wright, Fadeke Agboke, Manasa Muthu, Katherine A. Michaelis, Miles A. Mundy, Ping La, Guang Yang, Phyllis A. Dennery

J Biol Chem. 2012 Feb 24; 287(9): 6230–6239. Published online 2012 Jan 5. doi: 10.1074/jbc.M111.318246

PMCID:: PMC3307281

Abstract Article PDF–2.9M

Select item 328400012.

IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism

Nadine Bakkar, Katherine Ladner, Benjamin D. Canan, Sandya Liyanarachchi, Naresh C. Bal, Meghna Pant, Muthu Periasamy, Qiutang Li, Paul M.L. Janssen, Denis C. Guttridge

J Cell Biol. 2012 Feb 20; 196(4): 497–511. doi: 10.1083/jcb.201108118

PMCID:: PMC3284000

Abstract Article PDF–3.3M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 314128014.

IκBβ Attenuates Angiotensin II-Induced Cardiovascular Inflammation and Fibrosis in Mice

Shanqin Xu, Hui Zhi, Xiuyun Hou, Richard A. Cohen, Bingbing Jiang

Hypertension. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Hypertension. 2011 Aug; 58(2): 310–316. Published online 2011 Jun 6. doi: 10.1161/HYPERTENSIONAHA.111.172031

PMCID:: PMC3141280

Abstract Article PDF–3.5M

Select item 311015115.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

Select item 298976816.

IκBβ is an essential co-activator for LPS-induced IL-1β transcription in vivo

Melanie Scheibel, Bettina Klein, Heidrun Merkle, Manon Schulz, Ralph Fritsch, Florian R. Greten, Melek C. Arkan, Günter Schneider, Roland M. Schmid

J Exp Med. 2010 Nov 22; 207(12): 2621–2630. doi: 10.1084/jem.20100864

PMCID:: PMC2989768

Abstract Article PDF–1.6M

Select item 294637117.

I?Bß acts to both inhibit and activate gene expression at different stages of the inflammatory response

Ping Rao, Mathew S. Hayden, Meixiao Long, Martin L. Scott, A. Philip West, Dekai Zhang, Andrea Oeckinghaus, Candace Lynch, Alexander Hoffmann, David Baltimore, Sankar Ghosh

Nature. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: Nature. 2010 Aug 26; 466(7310): 1115–1119. doi: 10.1038/nature09283

PMCID:: PMC2946371

Abstract Article PDF–1.2M

Select item 289114918.

Role of Calcineurin, hnRNPA2 and Akt in Mitochondrial Respiratory Stress-Mediated Transcription Activation of Nuclear Gene Targets

Manti Guha, Weigang Tang, Neal Sondheimer, Narayan G. Avadhani

Biochim Biophys Acta. Author manuscript; available in PMC 2010 Jul 1.

Published in final edited form as: Biochim Biophys Acta. 2010 Jun–Jul; 1797(6-7): 1055–1065. Published online 2010 Feb 11. doi: 10.1016/j.bbabio.2010.02.008

PMCID:: PMC2891149

Abstract Article PDF–2.3M

Select item 267370819.

A homeostatic model of IκB metabolism to control constitutive NF-κB activity

Ellen L O'Dea, Derren Barken, Raechel Q Peralta, Kim T Tran, Shannon L Werner, Jeffrey D Kearns, Andre Levchenko, Alexander Hoffmann

Mol Syst Biol. 2007; 3: 111. Published online 2007 May 8. doi: 10.1038/msb4100148

PMCID:: PMC2673708

Abstract Article PDF–216K

Select item 233535520.

A Distinctive Physiological Role for IκBβ in the Propagation of Mitochondrial Respiratory Stress Signaling

Gopa Biswas, Weigang Tang, Neal Sondheimer, Manti Guha, Seema Bansal, Narayan G. Avadhani

J Biol Chem. 2008 May 2; 283(18): 12586–12594. doi: 10.1074/jbc.M710481200

PMCID:: PMC2335355

Abstract Article PDF–526K

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