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Select item 111720851.

Cholesterol Dietary Intake and Tumor Cell Homeostasis Drive Early Epithelial Tumorigenesis: A Potential Modelization of Early Prostate Tumorigenesis

Marine Vialat, Elissa Baabdaty, Amalia Trousson, Ayhan Kocer, Jean-Marc A. Lobaccaro, Silvère Baron, Laurent Morel, Cyrille de Joussineau

Cancers (Basel) 2024 Jun; 16(11): 2153. Published online 2024 Jun 6. doi: 10.3390/cancers16112153

PMCID:: PMC11172085

Abstract Article PDF–11M

Select item 110905172.

Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

Mariana I Tsap, Andriy S Yatsenko, Jan Hegermann, Bibiana Beckmann, Dimitrios Tsikas, Halyna R Shcherbata

eLife. 2024; 13: e98020. Published online 2024 Apr 25. doi: 10.7554/eLife.98020

PMCID:: PMC11090517

Abstract Article PDF–9.3M

Select item 106450793.

Structure and molecular basis of spermatid elongation in the Drosophila testis

Qiuru Huang, Xia Chen, Hao Yu, Li Ji, Yi Shi, Xinmeng Cheng, Hao Chen, Jun Yu

Open Biol. 2023 Nov; 13(11): 230136. Published online November 8, 2023. doi: 10.1098/rsob.230136

PMCID:: PMC10645079

Abstract Article PDF–1.0M

Select item 105813874.

Glycosphingolipids are linked to elevated neurotransmission and neurodegeneration in a Drosophila model of Niemann Pick type C

Anna E. Eberwein, Swarat S. Kulkarni, Emma Rushton, Kendal Broadie

Dis Model Mech. 2023 Oct 1; 16(10): dmm050206. Published online 2023 Oct 12. doi: 10.1242/dmm.050206

PMCID:: PMC10581387

Abstract Article

Select item 102729015.

Humanization for neurological disease modeling: A roadmap to increase the potential of Drosophila model systems

Vladimir L. Katanaev

Animal Model Exp Med. 2023 Jun; 6(3): 230–236. Published online 2023 May 8. doi: 10.1002/ame2.12322

PMCID:: PMC10272901

Abstract Article PDF–877K

Select item 102317926.

Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity

Meigen Yu, Hui Ye, Ruth B. De-Paula, Carl Grant Mangleburg, Timothy Wu, Tom V. Lee, Yarong Li, Duc Duong, Bridget Phillips, Carlos Cruchaga, Genevera I. Allen, Nicholas T. Seyfried, Ismael Al-Ramahi, Juan Botas, Joshua M. Shulman

PLoS Genet. 2023 May; 19(5): e1010760. Published online 2023 May 18. doi: 10.1371/journal.pgen.1010760

PMCID:: PMC10231792

Abstract Article PDF–1.9M

Select item 80008507.

Exploiting the Potential of Drosophila Models in Lysosomal Storage Disorders: Pathological Mechanisms and Drug Discovery

Laura Rigon, Concetta De Filippis, Barbara Napoli, Rosella Tomanin, Genny Orso

Biomedicines. 2021 Mar; 9(3): 268. Published online 2021 Mar 7. doi: 10.3390/biomedicines9030268

PMCID:: PMC8000850

Abstract Article PDF–2.8M

Select item 77300768.

Understanding and Treating Niemann–Pick Type C Disease: Models Matter

Valentina Pallottini, Frank W. Pfrieger

Int J Mol Sci. 2020 Dec; 21(23): 8979. Published online 2020 Nov 26. doi: 10.3390/ijms21238979

PMCID:: PMC7730076

Abstract Article PDF–2.0M

Select item 76551049.

Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila

Bhavatharini Kasinathan, Serafin U Colmenares, III, Hannah McConnell, Janet M Young, Gary H Karpen, Harmit S Malik

eLife. 2020; 9: e63368. Published online 2020 Nov 10. doi: 10.7554/eLife.63368

PMCID:: PMC7655104

Abstract Article PDF–1.7M

Select item 655002110.

Functional analysis of Niemann-Pick disease type C family protein, NPC1a, in Drosophila melanogaster

Tzofia Bialistoky, Diane Manry, Peyton Smith, Christopher Ng, Yunah Kim, Sol Zamir, Victoria Moyal, Rachel Kalifa, Paul Schedl, Offer Gerlitz, Girish Deshpande

Development. 2019 May 15; 146(10): dev168427. Published online 2019 May 15. doi: 10.1242/dev.168427

PMCID:: PMC6550021

Abstract Article

Select item 604588111.

Refining a steroidogenic model: an analysis of RNA-seq datasets from insect prothoracic glands

Panagiotis Moulos, Alexandros Alexandratos, Ioannis Nellas, Skarlatos G. Dedos

BMC Genomics. 2018; 19: 537. Published online 2018 Jul 13. doi: 10.1186/s12864-018-4896-2

PMCID:: PMC6045881

Abstract Article PDF–5.0M

Select item 589891212.

A gene-specific T2A-GAL4 library for Drosophila

Pei-Tseng Lee, Jonathan Zirin, Oguz Kanca, Wen-Wen Lin, Karen L Schulze, David Li-Kroeger, Rong Tao, Colby Devereaux, Yanhui Hu, Verena Chung, Ying Fang, Yuchun He, Hongling Pan, Ming Ge, Zhongyuan Zuo, Benjamin E Housden, Stephanie E Mohr, Shinya Yamamoto, Robert W Levis, Allan C Spradling, Norbert Perrimon, Hugo J Bellen

eLife. 2018; 7: e35574. Published online 2018 Mar 22. doi: 10.7554/eLife.35574

PMCID:: PMC5898912

Abstract Article PDF–4.9M

Select item 570780513.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900214.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 533355215.

The Insect Prothoracic Gland as a Model for Steroid Hormone Biosynthesis and Regulation

Qiuxiang Ou, Jie Zeng, Naoki Yamanaka, Christina Brakken-Thal, Michael B. O’Connor, Kirst King-Jones

Cell Rep. Author manuscript; available in PMC 2017 Mar 2.

Published in final edited form as: Cell Rep. 2016 Jun 28; 16(1): 247–262. Published online 2016 Jun 16. doi: 10.1016/j.celrep.2016.05.053

PMCID:: PMC5333552

Abstract Article PDF–2.7M

Select item 529559416.

Transcriptome Analysis of Drosophila melanogaster Third Instar Larval Ring Glands Points to Novel Functions and Uncovers a Cytochrome p450 Required for Development

Danielle Christesen, Ying Ting Yang, Jason Somers, Charles Robin, Tamar Sztal, Philip Batterham, Trent Perry

G3 (Bethesda) 2017 Feb; 7(2): 467–479. Published online 2016 Dec 13. doi: 10.1534/g3.116.037333

PMCID:: PMC5295594

Abstract Article PDF–1.6M

Select item 491845517.

A Drosophila genome-wide screen identifies regulators of steroid hormone production and developmental timing

E. Thomas Danielsen, Morten E. Moeller, Naoki Yamanaka, Qiuxiang Ou, Janne M. Laursen, Caecilie Soenderholm, Ran Zhuo, Brian Phelps, Kevin Tang, Jie Zeng, Shu Kondo, Christian H. Nielsen, Eva B. Harvald, Nils J. Faergeman, Macy J. Haley, Kyle A. O’Connor, Kirst King-Jones, Michael B. O’Connor, Kim F. Rewitz

Dev Cell. Author manuscript; available in PMC 2017 Jun 20.

Published in final edited form as: Dev Cell. 2016 Jun 20; 37(6): 558–570. doi: 10.1016/j.devcel.2016.05.015

PMCID:: PMC4918455

Abstract Article PDF–2.5M

Select item 480554518.

A genome-wide resource for the analysis of protein localisation in Drosophila

Mihail Sarov, Christiane Barz, Helena Jambor, Marco Y Hein, Christopher Schmied, Dana Suchold, Bettina Stender, Stephan Janosch, Vinay Vikas KJ, RT Krishnan, Aishwarya Krishnamoorthy, Irene RS Ferreira, Radoslaw K Ejsmont, Katja Finkl, Susanne Hasse, Philipp Kämpfer, Nicole Plewka, Elisabeth Vinis, Siegfried Schloissnig, Elisabeth Knust, Volker Hartenstein, Matthias Mann, Mani Ramaswami, K VijayRaghavan, Pavel Tomancak, Frank Schnorrer

eLife. 2016; 5: e12068. Published online 2016 Feb 20. doi: 10.7554/eLife.12068

PMCID:: PMC4805545

Abstract Article PDF–9.1M

Select item 460415419.

Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells

Juanma Ramirez, Aitor Martinez, Benoit Lectez, So Young Lee, Maribel Franco, Rosa Barrio, Gunnar Dittmar, Ugo Mayor

PLoS One. 2015; 10(10): e0139083. Published online 2015 Oct 13. doi: 10.1371/journal.pone.0139083

PMCID:: PMC4604154

Abstract Article PDF–3.1M

Select item 458107220.

Separating from the pack: Molecular mechanisms of Drosophila spermatid individualization

Josefa Steinhauer

Spermatogenesis. 2015 May-Aug; 5(2): e1041345. Published online 2015 May 21. doi: 10.1080/21565562.2015.1041345

PMCID:: PMC4581072

Article PDF–247K

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