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Select item 110548421.

Nicotinic Acetylcholine Receptor Alpha6 Contributes to Antiviral Immunity via IMD Pathway in Drosophila melanogaster

Zhiying Wang, Xiaoju Lin, Wangpeng Shi, Chuan Cao

Viruses. 2024 Apr; 16(4): 562. Published online 2024 Apr 3. doi: 10.3390/v16040562

Correction in:: Viruses. 2024 May; 16(5): 742.

PMCID:: PMC11054842

Abstract Article PDF–1.8M

Select item 109455082.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 109359543.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 109334774.

Drosophila eIF3f1 mediates host immune defense by targeting dTak1

Yixuan Hu, Fanrui Kong, Huimin Guo, Yongzhi Hua, Yangyang Zhu, Chuchu Zhang, Abdul Qadeer, Yihua Xiao, Qingshuang Cai, Shanming Ji

EMBO Rep. 2024 Mar; 25(3): 1415–1435. Published online 2024 Jan 26. doi: 10.1038/s44319-024-00067-z

PMCID:: PMC10933477

Abstract Article PDF–3.5M

Select item 108693625.

The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy

Shannon Nicolson, Jantina A. Manning, Yoon Lim, Xin Jiang, Erica Kolze, Sonia Dayan, Ruchi Umargamwala, Tianqi Xu, Jarrod J. Sandow, Andrew I. Webb, Sharad Kumar, Donna Denton

Commun Biol. 2024; 7: 183. Published online 2024 Feb 15. doi: 10.1038/s42003-024-05834-1

PMCID:: PMC10869362

Abstract Article PDF–6.1M

Select item 107246946.

The adaptor protein 14-3-3zeta modulates intestinal immunity and aging in Drosophila

Xiaolan Fan, Tiantian Huang, Shuai Wang, Ziyue Yang, Wenhao Song, Yao Zeng, Yingdong Tong, Yujuan Cai, Deying Yang, Bo Zeng, Mingwang Zhang, Qingyong Ni, Yan Li, Diyan Li, Mingyao Yang

J Biol Chem. 2023 Dec; 299(12): 105414. Published online 2023 Oct 31. doi: 10.1016/j.jbc.2023.105414

PMCID:: PMC10724694

Abstract Article PDF–2.7M

Select item 106974167.

Systematic assessment of transcriptomic and metabolic reprogramming by blue light exposure coupled with aging

Jia Huang, Fan Zhou, Huanchan Zhou, Xiaoqi Zheng, Zhengyi Huo, Meng Yang, Zihe Xu, Runzhou Liu, Luoluo Wang, Xiaoyun Wang

PNAS Nexus. 2023 Dec; 2(12): pgad390. Published online 2023 Dec 5. doi: 10.1093/pnasnexus/pgad390

PMCID:: PMC10697416

Abstract Article PDF–1.3M

Select item 106849098.

Gcm counteracts Toll-induced inflammation and impacts hemocyte number through cholinergic signaling

Wael Bazzi, Sara Monticelli, Claude Delaporte, Céline Riet, Angela Giangrande, Pierre B. Cattenoz

Front Immunol. 2023; 14: 1293766. Published online 2023 Nov 15. doi: 10.3389/fimmu.2023.1293766

PMCID:: PMC10684909

Abstract Article PDF–6.0M

Select item 106164859.

Interactions between innate immunity and insulin signaling affect resistance to infection in insects

Andrea M. Darby, Brian P. Lazzaro

Front Immunol. 2023; 14: 1276357. Published online 2023 Oct 17. doi: 10.3389/fimmu.2023.1276357

Correction in:: Front Immunol. 2024; 15: 1400514.

PMCID:: PMC10616485

Abstract Article PDF–1.5M

Select item 1060910710.

The Sterol Transporter Npc2c Controls Intestinal Stem Cell Mitosis and Host–Microbiome Interactions in Drosophila

Constantina Neophytou, Euripides Soteriou, Chrysoula Pitsouli

Metabolites. 2023 Oct; 13(10): 1084. Published online 2023 Oct 16. doi: 10.3390/metabo13101084

PMCID:: PMC10609107

Abstract Article PDF–8.3M

Select item 1058097211.

Delayed host mortality and immune response upon infection with P. aeruginosa persister cells

Cody J. Hastings, Maya V. Keledjian, Laura Palanker Musselman, Cláudia N. H. Marques

Infect Immun. 2023 Oct; 91(10): e00246-23. Published online 2023 Sep 21. doi: 10.1128/iai.00246-23

PMCID:: PMC10580972

Abstract Article PDF–967K

Select item 1057942712.

Defective phagocytosis leads to neurodegeneration through systemic increased innate immune signaling

Johnny E. Elguero, Guangmei Liu, Katherine Tiemeyer, Shruthi Bandyadka, Heena Gandevia, Lauren Duro, Zhenhao Yan, Kimberly McCall

iScience. 2023 Oct 20; 26(10): 108052. Published online 2023 Sep 26. doi: 10.1016/j.isci.2023.108052

PMCID:: PMC10579427

Abstract Article PDF–4.3M

Select item 1057756513.

Heterochromatic silencing of immune‐related genes in glia is required for BBB integrity and normal lifespan in drosophila

Shunpan Shu, Mingsheng Jiang, Xue Deng, Wenkai Yue, Xu Cao, Kai Zhang, Zeqing Wang, Hao He, Jihong Cui, Qiangqiang Wang, Kun Qu, Yanshan Fang

Aging Cell. 2023 Oct; 22(10): e13947. Published online 2023 Aug 18. doi: 10.1111/acel.13947

PMCID:: PMC10577565

Abstract Article PDF–12M

Select item 1054721114.

Neuronal expression in Drosophila of an evolutionarily conserved metallophosphodiesterase reveals pleiotropic roles in longevity and odorant response

Kriti Gupta, Sveta Chakrabarti, Vishnu Janardan, Nishita Gogia, Sanghita Banerjee, Swarna Srinivas, Deepthi Mahishi, Sandhya S. Visweswariah

PLoS Genet. 2023 Sep; 19(9): e1010962. Published online 2023 Sep 21. doi: 10.1371/journal.pgen.1010962

PMCID:: PMC10547211

Abstract Article PDF–2.9M

Select item 1048312615.

Effect of aminergic signaling on the humoral innate immunity response of Drosophila

Giulia Cattabriga, Giorgia Giordani, Giuseppe Gargiulo, Valeria Cavaliere

Front Physiol. 2023; 14: 1249205. Published online 2023 Aug 24. doi: 10.3389/fphys.2023.1249205

PMCID:: PMC10483126

Abstract Article PDF–929K

Select item 1045186716.

Peroxiredoxins Play an Important Role in the Regulation of Immunity and Aging in Drosophila

Olena Odnokoz, Noah Earland, Marziyeh Badinloo, Vladimir I. Klichko, Judith Benes, William C. Orr, Svetlana N. Radyuk

Antioxidants (Basel) 2023 Aug; 12(8): 1616. Published online 2023 Aug 15. doi: 10.3390/antiox12081616

PMCID:: PMC10451867

Abstract Article PDF–4.1M

Select item 1043400417.

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

Microbiol Spectr. 2023 Jul-Aug; 11(4): e00777-23. Published online 2023 Jun 1. doi: 10.1128/spectrum.00777-23

PMCID:: PMC10434004

Abstract Article PDF–1.7M

Select item 1031778418.

Interactions with ectoparasitic mites induce host metabolic and immune responses in flies at the expense of reproduction-associated factors

Joshua B. Benoit, Joy Bose, Samuel T. Bailey, Michal Polak

Parasitology. 2020 Sep; 147(11): 1196–1205. Published online 2020 Jun 5. doi: 10.1017/S0031182020000918

PMCID:: PMC10317784

Abstract Article PDF–602K

Select item 1027036019.

Steroid hormone regulation of innate immunity in Drosophila melanogaster

Scott A. Keith

PLoS Genet. 2023 Jun; 19(6): e1010782. Published online 2023 Jun 15. doi: 10.1371/journal.pgen.1010782

PMCID:: PMC10270360

Abstract Article PDF–1.0M

Select item 1026415720.

Downregulation of Hsp90 and the Antimicrobial Peptide Mtk Suppresses Poly(GR)-Induced Neurotoxicity in C9ORF72-ALS/FTD

Soojin Lee, Yong-Woo Jun, Gabriel R. Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill Moore, Gopinath Krishnan, Bryan Ruiz-Juarez, Manuel Santana, Marine Pons, Neal Silverman, Zhiping Weng, Justin Ichida, Fen-Biao Gao

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1381–1390.e6. Published online 2023 Mar 16. doi: 10.1016/j.neuron.2023.02.029