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Select item 96475491.

Aging-associated REGγ proteasome decline predisposes to tauopathy

Jialu Tu, Haiyang Zhang, Ting Yang, Yun Liu, Solomon Kibreab, Yunpeng Zhang, Liangcai Gao, Robb E. Moses, Bert W. O'Malley, Jianru Xiao, Xiaotao Li

J Biol Chem. 2022 Nov; 298(11): 102571. Published online 2022 Oct 7. doi: 10.1016/j.jbc.2022.102571

PMCID:: PMC9647549

Abstract Article PDF–5.7M

Select item 79387702.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 77848503.

REGγ controls Th17 cell differentiation and autoimmune inflammation by regulating dendritic cells

Lei Zhou, Liangfang Yao, Qing Zhang, Wei Xie, Xiaoshuang Wang, Huihui Zhang, Jinjin Xu, Qingxia Lin, Qing Li, Yang Xuan, Lei Ji, Lu Wang, Weicang Wang, Weichao Wang, Tingting Shi, Lei Fang, Biao Zheng, Lei Li, Shuang Liu, Bianhong Zhang, Xiaotao Li

Cell Mol Immunol. 2020 Nov; 17(11): 1136–1147. Published online 2019 Sep 11. doi: 10.1038/s41423-019-0287-0

PMCID:: PMC7784850

Abstract Article PDF–3.0M

Select item 74133844.

The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells

Xiao Gao, Qingwei Wang, Ying Wang, Jiang Liu, Shuang Liu, Jian Liu, Xingli Zhou, Li Zhou, Hui Chen, Linian Pan, Jiwei Chen, Da Wang, Qing Zhang, Shihui Shen, Yu Xiao, Zhipeng Wu, Yiyun Cheng, Geng Chen, Syeda Krubra, Jun Qin, Lan Huang, Pei Zhang, Chuangui Wang, Robb E. Moses, David M. Lonard, Bert W. O’ Malley, Fuad Fares, Bianhong Zhang, Xiaotao Li, Lei Li, Jianru Xiao

Nat Commun. 2020; 11: 3904. Published online 2020 Aug 6. doi: 10.1038/s41467-020-17667-7

Correction in:: Nat Commun. 2020; 11: 4888.

PMCID:: PMC7413384

Abstract Article PDF–2.0M

Select item 66023005.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 65228026.

MicroRNA-195-5p inhibitor prevents the development of osteoarthritis by targeting REGγ

Yang Shu, Junpeng Long, Weixiong Guo, Wei Ye

Mol Med Rep. 2019 Jun; 19(6): 4561–4568. Published online 2019 Apr 3. doi: 10.3892/mmr.2019.10124

PMCID:: PMC6522802

Abstract Article PDF–789K

Select item 64433377.

Proteasome activator REGγ promotes inflammation in Leydig cells via IkBε signaling

Tiancheng Xie, Hui Chen, Shihui Shen, Tingmei Huang, Bisheng Huang, Guanghui Hu, Lei Li, Yunfei Xu

Int J Mol Med. 2019 May; 43(5): 1961–1968. Published online 2019 Feb 27. doi: 10.3892/ijmm.2019.4115

PMCID:: PMC6443337

Abstract Article PDF–1.6M

Select item 63476438.

CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ

Jiao Fan, Lifeng Liu, Qingyan Liu, Yu Cui, Binwei Yao, Minghua Zhang, Yabing Gao, Yesheng Fu, Hongmiao Dai, Jingkun Pan, Ya Qiu, Cui Hua Liu, Fuchu He, Yu Wang, Lingqiang Zhang

Nat Commun. 2019; 10: 425. Published online 2019 Jan 25. doi: 10.1038/s41467-018-07895-3

Correction in:: Nat Commun. 2021; 12: 5670.

PMCID:: PMC6347643

Abstract Article PDF–3.7M

Select item 63334609.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 624418310.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 538122611.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 534152012.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

Select item 498753313.

Regulation of energy homeostasis by the ubiquitin-independent REGγ proteasome

Lianhui Sun, Guangjian Fan, Peipei Shan, Xiaoying Qiu, Shuxian Dong, Lujian Liao, Chunlei Yu, Tingting Wang, Xiaoyang Gu, Qian Li, Xiaoyu Song, Liu Cao, Xiaotao Li, Yongping Cui, Shengping Zhang, Chuangui Wang

Nat Commun. 2016; 7: 12497. Published online 2016 Aug 11. doi: 10.1038/ncomms12497

PMCID:: PMC4987533

Abstract Article PDF–2.8M

Select item 480238614.

Proteasome activators, PA28γ and PA200, play indispensable roles in male fertility

Lin Huang, Kousuke Haratake, Hatsumi Miyahara, Tomoki Chiba

Sci Rep. 2016; 6: 23171. Published online 2016 Mar 22. doi: 10.1038/srep23171

PMCID:: PMC4802386

Abstract Article PDF–1.1M

Select item 479311815.

Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice

Yiqing Lv, Bo Meng, Hao Dong, Tiantian Jing, Nan Wu, Yingying Yang, Lan Huang, Robb E Moses, Bert W O'Malley, Bing Mei, Xiaotao Li

Neuropsychopharmacology. 2016 Apr; 41(5): 1340–1349. Prepublished online 2015 Sep 15. Published online 2015 Oct 21. doi: 10.1038/npp.2015.285

PMCID:: PMC4793118

Abstract Article PDF–723K

Select item 476489916.

The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis

Jinjin Xu, Lei Zhou, Lei Ji, Fengyuan Chen, Karen Fortmann, Kun Zhang, Qingwu Liu, Ke Li, Weicang Wang, Hao Wang, Wei Xie, Qingwei Wang, Jiang Liu, Biao Zheng, Pei Zhang, Shixia Huang, Tieliu Shi, Biaohong Zhang, Yongyan Dang, Jiwu Chen, Bert W. O'Malley, Robb E. Moses, Ping Wang, Lei Li, Jianru Xiao, Alexander Hoffmann, Xiaotao Li

Nat Commun. 2016; 7: 10761. Published online 2016 Feb 22. doi: 10.1038/ncomms10761

PMCID:: PMC4764899

Abstract Article PDF–2.9M

Select item 474776817.

The LMO2 oncogene regulates DNA replication in hematopoietic cells

Marie-Claude Sincennes, Magali Humbert, Benoît Grondin, Véronique Lisi, Diogo F. T. Veiga, André Haman, Christophe Cazaux, Nazar Mashtalir, EL Bachir Affar, Alain Verreault, Trang Hoang

Proc Natl Acad Sci U S A. 2016 Feb 2; 113(5): 1393–1398. Published online 2016 Jan 13. doi: 10.1073/pnas.1515071113

PMCID:: PMC4747768

Abstract Article PDF–1.0M

Select item 474022918.

The 11S Proteasome Subunit PSME3 Is a Positive Feedforward Regulator of NF-κB and Important for Host Defense against Bacterial Pathogens

Jinxia Sun, Yi Luan, Dong Xiang, Xiao Tan, Hui Chen, Qi Deng, Jiaojiao Zhang, Minghui Chen, Hongjun Huang, Weichao Wang, Tingting Niu, Wenjie Li, Hu Peng, Shuangxi Li, Lei Li, Wenwen Tang, Xiaotao Li, Dianqing Wu, Ping Wang

Cell Rep. Author manuscript; available in PMC 2017 Feb 2.

Published in final edited form as: Cell Rep. 2016 Feb 2; 14(4): 737–749. Published online 2016 Jan 14. doi: 10.1016/j.celrep.2015.12.069

PMCID:: PMC4740229

Abstract Article PDF–1.7M

Select item 423731619.

PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis

Shuang Liu, Li Lai, Qiuhong Zuo, Fujun Dai, Lin Wu, Yan Wang, Qingxia Zhou, Jian Liu, Jiang Liu, Lei Li, Qingxiang Lin, Chad J. Creighton, Myra Grace Costello, Shixia Huang, Caifeng Jia, Lujian Liao, Honglin Luo, Junjiang Fu, Mingyao Liu, Zhengfang Yi, Jianru Xiao, Xiaotao Li

J Mol Cell Cardiol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: J Mol Cell Cardiol. 2014 Jul; 72: 28–38. Published online 2014 Feb 20. doi: 10.1016/j.yjmcc.2014.02.007

PMCID:: PMC4237316

Abstract Article PDF–2.9M

Select item 404710720.

Dusp3 and Psme3 Are Associated with Murine Susceptibility to Staphylococcus aureus Infection and Human Sepsis

Qin Yan, Batu K. Sharma-Kuinkel, Hitesh Deshmukh, Ephraim L. Tsalik, Derek D. Cyr, Joseph Lucas, Christopher W. Woods, William K. Scott, Gregory D. Sempowski, Joshua Thaden, Thomas H. Rude, Sun Hee Ahn, Vance G. Fowler, Jr

PLoS Pathog. 2014 Jun; 10(6): e1004149. Published online 2014 Jun 5. doi: 10.1371/journal.ppat.1004149

Correction in:: PLoS Pathog. 2014 Jun; 10(6): e1004259.

PMCID:: PMC4047107

Abstract Article PDF–4.0M

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