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Items: 1 to 20 of 108

1.
Structured and disordered regions of Ataxin-2 contribute differently to the specificity and efficiency of mRNP granule formation
Arnas Petrauskas, Daniel L. Fortunati, Arvind Reddy Kandi, Sai Shruti Pothapragada, Khushboo Agrawal, Amanjot Singh, Joern Huelsmeier, Jens Hillebrand, Georgia Brown, Dhananjay Chaturvedi, Jongbo Lee, Chunghun Lim, Georg Auburger, K. VijayRaghavan, Mani Ramaswami, Baskar Bakthavachalu
PLoS Genet. 2024 May; 20(5): e1011251. Published online 2024 May 20. doi: 10.1371/journal.pgen.1011251
PMCID:
PMC11166328
AbstractArticlePDF–3.2M
2.
Fly for ALS: Drosophila modeling on the route to amyotrophic lateral sclerosis modifiers
Francesco Liguori, Susanna Amadio, Cinzia Volonté
Cell Mol Life Sci. 2021 Sep; 78(17-18): 6143–6160. Published online 2021 Jul 28. doi: 10.1007/s00018-021-03905-8
PMCID:
PMC11072332
AbstractArticlePDF–1.2M
3.
Large-language models facilitate discovery of the molecular signatures regulating sleep and activity
Di Peng, Liubin Zheng, Dan Liu, Cheng Han, Xin Wang, Yan Yang, Li Song, Miaoying Zhao, Yanfeng Wei, Jiayi Li, Xiaoxue Ye, Yuxiang Wei, Zihao Feng, Xinhe Huang, Miaomiao Chen, Yujie Gou, Yu Xue, Luoying Zhang
Nat Commun. 2024; 15: 3685. Published online 2024 May 1. doi: 10.1038/s41467-024-48005-w
PMCID:
PMC11063160
AbstractArticlePDF–2.7M
4.
A regulatory role for the unstructured C-terminal domain of the CtBP transcriptional corepressor
Ana-Maria Raicu, Megha Suresh, David N. Arnosti
J Biol Chem. 2024 Jan; 300(1): 105490. Published online 2023 Nov 23. doi: 10.1016/j.jbc.2023.105490
PMCID:
PMC10788531
AbstractArticlePDF–1.4M
5.
TDP-43 impairs sleep in Drosophila through Ataxin-2–dependent metabolic disturbance
Alexandra E. Perlegos, Jaclyn Durkin, Samuel J. Belfer, Anyara Rodriguez, Oksana Shcherbakova, Kristen Park, Jenny Luong, Nancy M. Bonini, Matthew S. Kayser
Sci Adv. 2024 Jan 12; 10(2): eadj4457. Published online 2024 Jan 10. doi: 10.1126/sciadv.adj4457
PMCID:
PMC10780954
AbstractArticlePDF–2.1M
6.
dTrmt10A impacts Hsp70 chaperone m6A levels and the stress response in the Drosophila brain
Alexandra E. Perlegos, Xiuming Quan, Kirby M. Donnelly, Hui Shen, Emily J. Shields, Heidi Elashal, Kathy Fange Liu, Nancy M. Bonini
Sci Rep. 2023; 13: 22999. Published online 2023 Dec 28. doi: 10.1038/s41598-023-50272-4
PMCID:
PMC10754819
AbstractArticlePDF–2.6M
7.
On the identification of potential novel therapeutic targets for spinocerebellar ataxia type 1 (SCA1) neurodegenerative disease using EvoPPI3
André Sousa, Sara Rocha, Jorge Vieira, Miguel Reboiro-Jato, Hugo López-Fernández, Cristina P. Vieira
J Integr Bioinform. 2023 Jun; 20(2): 20220056. Published online 2023 Feb 28. doi: 10.1515/jib-2022-0056
PMCID:
PMC10561075
AbstractArticlePDF–1.2M
8.
The identification of protein and RNA interactors of the splicing factor Caper in the adult Drosophila nervous system
M. Brandon Titus, Adeline W. Chang, Niko Popitsch, Christopher C. Ebmeier, Jeremy M. Bono, Eugenia C. Olesnicky
Front Mol Neurosci. 2023; 16: 1114857. Published online 2023 Jun 23. doi: 10.3389/fnmol.2023.1114857
PMCID:
PMC10332324
AbstractArticlePDF–4.5M
9.
Drosophila melanogaster as a model to study autophagy in neurodegenerative diseases induced by proteinopathies
Stefania Santarelli, Chiara Londero, Alessia Soldano, Carlotta Candelaresi, Leonardo Todeschini, Luisa Vernizzi, Paola Bellosta
Front Neurosci. 2023; 17: 1082047. Published online 2023 May 18. doi: 10.3389/fnins.2023.1082047
PMCID:
PMC10232775
AbstractArticlePDF–2.4M
10.
Next-generation large-scale binary protein interaction network for Drosophila melanogaster
Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr
Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0
PMCID:
PMC10105736
AbstractArticlePDF–3.2M
11.
Experience-dependent plasticity in the olfactory system of Drosophila melanogaster and other insects
Benjamin Fabian, Silke Sachse
Front Cell Neurosci. 2023; 17: 1130091. Published online 2023 Feb 22. doi: 10.3389/fncel.2023.1130091
PMCID:
PMC10010147
AbstractArticlePDF–1.7M
12.
A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes
Karen Jule Nieken, Kathryn O’Brien, Alexander McDonnell, Liudmila Zhaunova, Hiroyuki Ohkura
Chromosoma. 2023; 132(1): 1–18. Published online 2023 Jan 17. doi: 10.1007/s00412-023-00784-9
PMCID:
PMC9981535
AbstractArticlePDF–3.4M
13.
The making of the Drosophila mushroom body
Suewei Lin
Front Physiol. 2023; 14: 1091248. Published online 2023 Jan 13. doi: 10.3389/fphys.2023.1091248
PMCID:
PMC9880076
AbstractArticlePDF–2.2M
14.
Drosophila exercise, an emerging model bridging the fields of exercise and aging in human
Meng Ding, Hongyu Li, Lan Zheng
Front Cell Dev Biol. 2022; 10: 966531. Published online 2022 Sep 9. doi: 10.3389/fcell.2022.966531
PMCID:
PMC9507000
AbstractArticlePDF–1.2M
15.
Ataxin-2, Twenty-four, and Dicer-2 are components of a noncanonical cytoplasmic polyadenylation complex
Hima Priyanka Nadimpalli, Tanit Guitart, Olga Coll, Fátima Gebauer
Life Sci Alliance. 2022 Dec; 5(12): e202201417. Published online 2022 Sep 16. doi: 10.26508/lsa.202201417
PMCID:
PMC9481931
AbstractArticlePDF–2.9M
16.
Identification of PSMB5 as a genetic modifier of fragile X–associated tremor/ataxia syndrome
Ha Eun Kong, Junghwa Lim, Alexander Linsalata, Yunhee Kang, Indranil Malik, Emily G. Allen, Yiqu Cao, Lisa Shubeck, Rich Johnston, Yanting Huang, Yanghong Gu, Xiangxue Guo, Michael E. Zwick, Zhaohui Qin, Thomas S. Wingo, Jorge Juncos, David L. Nelson, Michael P. Epstein, David J. Cutler, Peter K. Todd, Stephanie L. Sherman, Stephen T. Warren, Peng Jin
Proc Natl Acad Sci U S A. 2022 May 31; 119(22): e2118124119. Published online 2022 May 26. doi: 10.1073/pnas.2118124119
PMCID:
PMC9295734
AbstractArticlePDF–2.3M
17.
The transcriptional response to oxidative stress is independent of stress-granule formation
Amanjot Singh, Arvind Reddy Kandi, Deepa Jayaprakashappa, Guillaume Thuery, Devam J. Purohit, Joern Huelsmeier, Rashi Singh, Sai Shruti Pothapragada, Mani Ramaswami, Baskar Bakthavachalu
Mol Biol Cell. 2022 Mar 1; 33(3): ar25. Published online 2022 Feb 18. doi: 10.1091/mbc.E21-08-0418
PMCID:
PMC9250384
AbstractArticlePDF–6.9M
18.
Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters
Ana López-Varea, Cristina M Ostalé, Patricia Vega-Cuesta, Ana Ruiz-Gómez, María F Organista, Mercedes Martín, Covadonga F Hevia, Cristina Molnar, Jesús de Celis, Joaquim Culi, Nuria Esteban, Jose F de Celis
G3 (Bethesda) 2021 Dec; 11(12): jkab351. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab351
PMCID:
PMC8962446
AbstractArticlePDF–2.0M
19.
The disease-associated proteins Drosophila Nab2 and Ataxin-2 interact with shared RNAs and coregulate neuronal morphology
J Christopher Rounds, Edwin B Corgiat, Changtian Ye, Joseph A Behnke, Seth M Kelly, Anita H Corbett, Kenneth H Moberg
Genetics. 2022 Jan; 220(1): iyab175. Published online 2022 Jan 3. doi: 10.1093/genetics/iyab175
PMCID:
PMC8733473
AbstractArticlePDF–2.4M
20.
Ataxin-2 is essential for cytoskeletal dynamics and neurodevelopment in Drosophila
Urko del Castillo, Rosalind Norkett, Wen Lu, Anna Serpinskaya, Vladimir I. Gelfand
iScience. 2022 Jan 21; 25(1): 103536. Published online 2021 Dec 3. doi: 10.1016/j.isci.2021.103536
PMCID:
PMC8689088
AbstractArticlePDF–4.2M

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