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Select item 109578971.

An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

Grace Y. Liu, Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini

Nat Commun. 2024; 15: 2517. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46680-3

PMCID:: PMC10957897

Abstract Article PDF–2.0M

Select item 106655742.

Protein modification regulated autophagy in Bombyx mori and Drosophila melanogaster

Wenmei Wu, Luobin Lin, Yuntao Zhao, Huaqin Li, Rongxin Zhang

Front Physiol. 2023; 14: 1281555. Published online 2023 Nov 9. doi: 10.3389/fphys.2023.1281555

PMCID:: PMC10665574

Abstract Article PDF–1.1M

Select item 102049573.

TORC1 regulation of dendrite regrowth after pruning is linked to actin and exocytosis

Neeraja Sanal, Lorena Keding, Ulrike Gigengack, Esther Michalke, Sebastian Rumpf

PLoS Genet. 2023 May; 19(5): e1010526. Published online 2023 May 11. doi: 10.1371/journal.pgen.1010526

PMCID:: PMC10204957

Abstract Article PDF–4.4M

Select item 91180354.

A genetic screen in Drosophila reveals the role of fucosylation in host susceptibility to Candida infection

Marcus T. Glittenberg, Ilias Kounatidis, Magda Atilano, Petros Ligoxygakis

Dis Model Mech. 2022 May 1; 15(5): dmm049218. Published online 2022 May 9. doi: 10.1242/dmm.049218

PMCID:: PMC9118035

Abstract Article

Select item 88330925.

An intestinal zinc sensor regulates food intake and developmental growth

Siamak Redhai, Clare Pilgrim, Pedro Gaspar, Lena van Giesen, Tatiana Lopes, Olena Riabinina, Théodore Grenier, Alexandra Milona, Bhavna Chanana, Jacob B. Swadling, Yi-Fang Wang, Farah Dahalan, Michaela Yuan, Michaela Wilsch-Brauninger, Wei-hsiang Lin, Nathan Dennison, Paolo Capriotti, Mara K.N. Lawniczak, Richard A. Baines, Tobias Warnecke, Nikolai Windbichler, Francois Leulier, Nicholas Bellono, Irene Miguel-Aliaga

Nature. Author manuscript; available in PMC 2022 Feb 11.

Published in final edited form as: Nature. 2020 Apr; 580(7802): 263–268. Published online 2020 Mar 18. doi: 10.1038/s41586-020-2111-5

PMCID:: PMC8833092

Abstract Article PDF–6.2M

Select item 86644866.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 86023877.

Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism

Katrin Strassburger, Marilena Lutz, Sandra Müller, Aurelio A. Teleman

Nat Commun. 2021; 12: 6684. Published online 2021 Nov 18. doi: 10.1038/s41467-021-26780-0

PMCID:: PMC8602387

Abstract Article PDF–3.2M

Select item 85284898.

Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size

Alessandro Bonfini, Adam J Dobson, David Duneau, Jonathan Revah, Xi Liu, Philip Houtz, Nicolas Buchon

eLife. 2021; 10: e64125. Published online 2021 Sep 23. doi: 10.7554/eLife.64125

PMCID:: PMC8528489

Abstract Article PDF–12M

Select item 76579779.

The Rag GTPase regulates the dynamic behavior of TSC downstream of both amino acid and growth factor restriction

Shu Yang, Yingbiao Zhang, Chun-Yuan Ting, Lucia Bettedi, Kuikwon Kim, Elena Ghaniam, Mary Lilly

Dev Cell. Author manuscript; available in PMC 2021 Nov 9.

Published in final edited form as: Dev Cell. 2020 Nov 9; 55(3): 272–288.e5. Published online 2020 Sep 7. doi: 10.1016/j.devcel.2020.08.006

PMCID:: PMC7657977

Abstract Article PDF–3.2M

Select item 755019210.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 753685411.

Regulation of Body Size and Growth Control

Michael J. Texada, Takashi Koyama, Kim Rewitz

Genetics. 2020 Oct; 216(2): 269–313. Published online 2020 Jul 6. doi: 10.1534/genetics.120.303095

PMCID:: PMC7536854

Abstract Article PDF–2.2M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 635606413.

RagC phosphorylation autoregulates mTOR complex 1

Guang Yang, Sean J Humphrey, Danielle S Murashige, Deanne Francis, Qiao‐Ping Wang, Kristen C Cooke, G Gregory Neely, David E James

EMBO J. 2019 Feb 1; 38(3): e99548. Published online 2018 Dec 14. doi: 10.15252/embj.201899548

PMCID:: PMC6356064

Abstract Article PDF–1.0M

Select item 570780514.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900215.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 549917416.

Genetic Dissection of Nutrition-Induced Plasticity in Insulin/Insulin-Like Growth Factor Signaling and Median Life Span in a Drosophila Multiparent Population

Patrick D. Stanley, Enoch Ng’oma, Siri O’Day, Elizabeth G. King

Genetics. 2017 Jun; 206(2): 587–602. Published online 2017 Jun 6. doi: 10.1534/genetics.116.197780

PMCID:: PMC5499174

Abstract Article PDF–1.7M

Select item 488965817.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 486895118.

eIF4A inactivates TORC1 in response to amino acid starvation

Foivos‐Filippos Tsokanos, Marie‐Astrid Albert, Constantinos Demetriades, Kerstin Spirohn, Michael Boutros, Aurelio A Teleman

EMBO J. 2016 May 17; 35(10): 1058–1076. Published online 2016 Mar 17. doi: 10.15252/embj.201593118

PMCID:: PMC4868951

Abstract Article PDF–2.0M

Select item 483189119.

A genetic interaction map of cell cycle regulators

Maximilian Billmann, Thomas Horn, Bernd Fischer, Thomas Sandmann, Wolfgang Huber, Michael Boutros

Mol Biol Cell. 2016 Apr 15; 27(8): 1397–1407. doi: 10.1091/mbc.E15-07-0467

PMCID:: PMC4831891

Abstract Article PDF–4.0M

Select item 459123720.

Diminished MTORC1-Dependent JNK-Activation Underlies Neurodevelopmental Defects Associated with Lysosomal Dysfunction

Ching-On Wong, Michela Palmieri, Jiaxing Li, Dmitry Akhmedov, Yufang Chao, Geoffrey T. Broadhead, Michael X. Zhu, Rebecca Berdeaux, Catherine A. Collins, Marco Sardiello, Kartik Venkatachalam

Cell Rep. Author manuscript; available in PMC 2016 Sep 29.

Published in final edited form as: Cell Rep. 2015 Sep 29; 12(12): 2009–2020. Published online 2015 Sep 17. doi: 10.1016/j.celrep.2015.08.047

PMCID:: PMC4591237

Abstract Article PDF–3.4M

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