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Select item 86644861.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 75501922.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 71935643.

CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila

Menghua Wu, Xuedi Zhang, Wei Wei, Li Long, Sainan An, Guanjun Gao

Sci Rep. 2020; 10: 7383. Published online 2020 Apr 30. doi: 10.1038/s41598-020-64253-4

PMCID:: PMC7193564

Abstract Article PDF–1.8M

Select item 69615784.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 59313695.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556

PMCID:: PMC5931369

Abstract Article PDF–2.9M

Select item 57078056.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890027.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 51236898.

Atg1-independent induction of autophagy by the Drosophila Ulk3 homolog, ADUK

Christopher R. Braden, Thomas P. Neufeld

FEBS J. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: FEBS J. 2016 Nov; 283(21): 3889–3897. Published online 2016 Oct 11. doi: 10.1111/febs.13906

PMCID:: PMC5123689

Abstract Article PDF–1.5M

Select item 49280479.

Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome

Heath A. MacMillan, Jose M. Knee, Alice B. Dennis, Hiroko Udaka, Katie E. Marshall, Thomas J. S. Merritt, Brent J. Sinclair

Sci Rep. 2016; 6: 28999. Published online 2016 Jun 30. doi: 10.1038/srep28999

PMCID:: PMC4928047

Abstract Article PDF–3.1M

Select item 457069710.

Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach

Flavio Pazos Obregón, Cecilia Papalardo, Sebastián Castro, Gustavo Guerberoff, Rafael Cantera

BMC Genomics. 2015; 16(1): 694. Published online 2015 Sep 15. doi: 10.1186/s12864-015-1888-3

PMCID:: PMC4570697

Abstract Article PDF–2.0M

Select item 452833011.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832912.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435288713.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 427152714.

Phylostratigraphic Bias Creates Spurious Patterns of Genome Evolution

Bryan A. Moyers, Jianzhi Zhang

Mol Biol Evol. 2015 Jan 1; 32(1): 258–267. Published online 2014 Oct 13. doi: 10.1093/molbev/msu286

Correction in:: Mol Biol Evol. 2016 Nov; 33(11): 3031.

PMCID:: PMC4271527

Abstract Article PDF–618K

Select item 420866715.

Combining Genetic Perturbations and Proteomics to Examine Kinase-Phosphatase Networks in Drosophila Embryos

Richelle Sopko, Marianna Foos, Arunachalam Vinayagam, Bo Zhai, Richard Binari, Yanhui Hu, Sakara Randklev, Lizabeth A. Perkins, Steven P. Gygi, Norbert Perrimon

Dev Cell. Author manuscript; available in PMC 2015 Oct 13.

Published in final edited form as: Dev Cell. 2014 Oct 13; 31(1): 114–127. Published online 2014 Oct 2. doi: 10.1016/j.devcel.2014.07.027

PMCID:: PMC4208667

Abstract Article PDF–2.4M

Select item 402015416.

Genetic screens reveal RAS/MAPK/MSK1 modulate ataxin 1 protein levels and toxicity in SCA1

Jeehye Park, Ismael Al-Ramahi, Qiumin Tan, Nissa Mollema, Javier R. Diaz-Garcia, Tatiana Gallego-Flores, Hsiang-Chih Lu, Sarita Lagalwar, Lisa Duvick, Hyojin Kang, Yoontae Lee, Paymaan Jafar-Nejad, Layal S. Sayegh, Ronald Richman, Xiuyun Liu, Yan Gao, Chad A. Shaw, J. Simon C. Arthur, Harry T. Orr, Thomas F. Westbrook, Juan Botas, Huda Y. Zoghbi

Nature. Author manuscript; available in PMC 2014 May 14.

Published in final edited form as: Nature. 2013 Jun 20; 498(7454): 325–331. Published online 2013 May 29. doi: 10.1038/nature12204

PMCID:: PMC4020154

Abstract Article PDF–4.3M

Select item 371249917.

A Screen for Morphological Complexity Identifies Regulators of Switch-like Transitions between Discrete Cell Shapes

Zheng Yin, Amine Sadok, Heba Sailem, Afshan McCarthy, Xiaofeng Xia, Fuhai Li, Mar Arias Garcia, Louise Evans, Alexis Barr, Norbert Perrimon, Christopher J Marshall, Stephen T.C. Wong, Chris Bakal

Nat Cell Biol. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Nat Cell Biol. 2013 Jul; 15(7): 860–871. Published online 2013 Jun 9. doi: 10.1038/ncb2764

PMCID:: PMC3712499

Abstract Article PDF–147M

Select item 353067718.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 346946719.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 304044120.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

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