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Items: 1 to 20 of 354

1.
CLU (clusterin) and PPARGC1A/PGC1α coordinately control mitophagy and mitochondrial biogenesis for oral cancer cell survival
Prakash P. Praharaj, Srimanta Patra, Amruta Singh, Debasna P. Panigrahi, Hwa Y. Lee, Mohammad F. Kabir, Muhammad K. Hossain, Samir K. Patra, Birija S. Patro, Shankargouda Patil, Daniel J. Klionsky, Han J. Chae, Sujit K. Bhutia
Autophagy. 2024; 20(6): 1359–1382. Published online 2024 Mar 6. doi: 10.1080/15548627.2024.2309904
PMCID:
PMC11210931
AbstractArticlePDF–12M
2.
PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in the retinal pigment epithelium
Shuyan Zhou, Kaan Taskintuna, Jacob Hum, Jasmine Gulati, Stephanie Olaya, Jeremy Steinman, Nady Golestaneh
Cell Death Dis. 2024 Jun; 15(6): 385. Published online 2024 Jun 1. doi: 10.1038/s41419-024-06762-y
PMCID:
PMC11144268
AbstractArticlePDF–13M
3.
Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α
Beibei Liu, Di Xie, Xinmei Huang, Sungho Jin, Yangyang Dai, Xiaoli Sun, Da Li, Anton M. Bennett, Sabrina Diano, Yingqun Huang
Diabetologia. 2024; 67(4): 724–737. Published online 2024 Jan 13. doi: 10.1007/s00125-023-06073-5
PMCID:
PMC10904493
AbstractArticlePDF–1.4M
4.
Association of Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1 Alpha Coding Variants with Hepatocellular Carcinoma Risk in the Moroccan Population: A Case-Control Study
Ikram-Allah Tanouti, Hassan Fellah, Raouia El Fihry, Chaimaa Zerrad, Karima Abounouh, Mohamed Tahiri, Abdelkader Belkouchi, Wafaa Badre, Pascal Pineau, Soumaya Benjelloun, Sayeh Ezzikouri
Asian Pac J Cancer Prev. 2023; 24(11): 3689–3696. doi: 10.31557/APJCP.2023.24.11.3689
PMCID:
PMC10772742
AbstractArticlePDF–492K
5.
ACE I/D, ACTN3 R577X, PPARD T294C and PPARGC1AGly482Ser polymorphisms and physical fitness in Taiwanese late adolescent girls
Li-Ling Chiu, Tzu-Wen Chen, Sandy S. Hsieh, Ling-Ling Hsieh
J Physiol Sci. 2012 Mar; 62(2): 115–121. Published online 2012 Jan 14. doi: 10.1007/s12576-011-0189-0
PMCID:
PMC10718015
AbstractArticlePDF–220K
6.
Exercise-induced expression of peroxisome proliferator-activated receptor γ coactivator-1α isoforms in skeletal muscle of endurance-trained males
Daniil V. Popov, Anton V. Bachinin, Evgeny A. Lysenko, Tatiana F. Miller, Olga L. Vinogradova
J Physiol Sci. 2014 Sep; 64(5): 317–323. Published online 2014 Jun 7. doi: 10.1007/s12576-014-0321-z
PMCID:
PMC10718011
AbstractArticlePDF–486K
7.
Peroxisome proliferator-activated receptor gamma co-activator 1 gene Gly482Ser polymorphism is associated with the response of low-density lipoprotein cholesterol concentrations to exercise training in elderly Japanese
Takuro Tobina, Yukari Mori, Yukiko Doi, Fuki Nakayama, Akira Kiyonaga, Hiroaki Tanaka
J Physiol Sci. 2017 Sep; 67(5): 595–602. Published online 2016 Oct 3. doi: 10.1007/s12576-016-0491-y
PMCID:
PMC10717479
AbstractArticlePDF–526K
8.
AAV‐Mediated nuclear localized PGC1α4 delivery in muscle ameliorates sarcopenia and aging‐associated metabolic dysfunctions
Mingwei Guo, Jun Zhang, Ying Ma, Zhenzhong Zhu, Hui Zuo, Jing Yao, Xia Wu, Dongmei Wang, Jian Yu, Meiyao Meng, Caizhi Liu, Yi Zhang, Jiangrong Chen, Jian Lu, Shuzhe Ding, Cheng Hu, Xinran Ma, Lingyan Xu
Aging Cell. 2023 Oct; 22(10): e13961. Published online 2023 Aug 16. doi: 10.1111/acel.13961
PMCID:
PMC10577532
AbstractArticlePDF–12M
9.
The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function
Simeon R. Mihaylov, Lydia M. Castelli, Ya-Hui Lin, Aytac Gül, Nikita Soni, Christopher Hastings, Helen R. Flynn, Oana Păun, Mark J. Dickman, Ambrosius P. Snijders, Robert Goldstone, Oliver Bandmann, Tatyana A. Shelkovnikova, Heather Mortiboys, Sila K. Ultanir, Guillaume M. Hautbergue
Nat Commun. 2023; 14: 5496. Published online 2023 Sep 7. doi: 10.1038/s41467-023-41304-8
PMCID:
PMC10485026
AbstractArticlePDF–5.0M
10.
Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism
Yunkun Liu, Nengwen Huang, Xianghe Qiao, Zhiyu Gu, Yongzhi Wu, Jinjin Li, Chengzhou Wu, Bo Li, Longjiang Li
Int J Oral Sci. 2023; 15: 37. Published online 2023 Sep 4. doi: 10.1038/s41368-023-00242-3
PMCID:
PMC10475463
AbstractArticlePDF–2.7M
11.
Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover
Mi Huang, Melina Claussnitzer, Alham Saadat, Daniel E. Coral, Sebastian Kalamajski, Paul W. Franks
Diabetologia. 2023; 66(7): 1289–1305. Published online 2023 May 12. doi: 10.1007/s00125-023-05915-6
PMCID:
PMC10244287
AbstractArticlePDF–13M
12.
Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas
Jiaxin Liang, Deyang Yu, Chi Luo, Christopher Bennett, Mark Jedrychowski, Steve P. Gygi, Hans R. Widlund, Pere Puigserver
Nat Commun. 2023; 14: 3251. Published online 2023 Jun 5. doi: 10.1038/s41467-023-38968-7
PMCID:
PMC10241879
AbstractArticlePDF–2.7M
13.
Association between the PPARGC1A Gly482Ser polymorphism and muscle fitness in Chinese schoolchildren
Qi Wei
PLoS One. 2023; 18(4): e0284827. Published online 2023 Apr 27. doi: 10.1371/journal.pone.0284827
PMCID:
PMC10138255
AbstractArticlePDF–533K
14.
Evidence of SARS-CoV-2 infection in postmortem lung, kidney, and liver samples, revealing cellular targets involved in COVID-19 pathogenesis
Viviana Falcón-Cama, Teresita Montero-González, Emilio F. Acosta-Medina, Gerardo Guillen-Nieto, Jorge Berlanga-Acosta, Celia Fernández-Ortega, Anabel Alfonso-Falcón, Nathalie Gilva-Rodríguez, Lilianne López-Nocedo, Daina Cremata-García, Mariuska Matos-Terrero, Giselle Pentón-Rol, Iris Valdés, Leonardo Oramas-Díaz, Anamarys Suarez-Batista, Enrique Noa-Romero, Otto Cruz-Sui, Daisy Sánchez, Amanda I. Borrego-Díaz, Juan E. Valdés-Carreras, Ananayla Vizcaino, José Suárez-Alba, Rodolfo Valdés-Véliz, Gretchen Bergado, Miguel A. González, Tays Hernandez, Rydell Alvarez-Arzola, Anna C. Ramírez-Suárez, Dionne Casillas-Casanova, Gilda Lemos-Pérez, Omar R. Blanco-Águila, Angelina Díaz, Yorexis González, Mónica Bequet-Romero, Javier Marín-Prida, Julio C. Hernández-Perera, Leticia del Rosario-Cruz, Alina P. Marin-Díaz, Maritza González-Bravo, Israel Borrajero, Nelson Acosta-Rivero
Arch Virol. 2023; 168(3): 96. Published online 2023 Feb 26. doi: 10.1007/s00705-023-05711-y
PMCID:
PMC9968404
AbstractArticlePDF–3.2M
15.
The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome
Eva M. G. Viho, A. Mattijs Punt, Ben Distel, René Houtman, Jan Kroon, Ype Elgersma, Onno C. Meijer
Int J Mol Sci. 2023 Jan; 24(1): 303. Published online 2022 Dec 24. doi: 10.3390/ijms24010303
PMCID:
PMC9820460
AbstractArticlePDF–3.4M
16.
Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population
Boyang Chen, Yafeng Wang, Weifeng Tang, Yu Chen, Chao Liu, Mingqiang Kang, Jinbiao Xie
BMC Med Genomics. 2022; 15: 274. Published online 2022 Dec 31. doi: 10.1186/s12920-022-01428-0
PMCID:
PMC9805199
AbstractArticlePDF–944K
17.
Analysis of Metabolic Regulators PGC1-α and PGC1-β in Oral Squamous Cell Carcinoma with and without Hyperglycemia
Tamizh Paavai Thamizhanambi, Annasamy Rameshkumar, Ramadoss Ramya, Rajkumar Krishnan, Thayalan Dineshkumar, Gunasekaran Nandhini
Asian Pac J Cancer Prev. 2022 Aug; 23(8): 2797–2803. doi: 10.31557/APJCP.2022.23.8.2797
PMCID:
PMC9741879
AbstractArticlePDF–332K
18.
Effects of PPARG and PPARGC1A gene polymorphisms on obesity markers
Carmen Muntean, Maria Oana Sasaran, Adriana Crisan, Claudia Banescu
Front Public Health. 2022; 10: 962852. Published online 2022 Nov 16. doi: 10.3389/fpubh.2022.962852
PMCID:
PMC9709282
AbstractArticlePDF–331K
19.
Association of Irisin/FNDC5 with ERRα and PGC-1α Expression in NSCLC
Katarzyna Nowińska, Karolina Jabłońska, Urszula Ciesielska, Aleksandra Piotrowska, Katarzyna Haczkiewicz-Leśniak, Konrad Pawełczyk, Marzenna Podhorska-Okołów, Piotr Dzięgiel
Int J Mol Sci. 2022 Nov; 23(22): 14204. Published online 2022 Nov 17. doi: 10.3390/ijms232214204
PMCID:
PMC9694131
AbstractArticlePDF–7.6M
20.
Survival Pathways of HIF-Deficient Tumour Cells: TCA Inhibition, Peroxisomal Fatty Acid Oxidation Activation and an AMPK-PGC-1α Hypoxia Sensor
Monika A. Golinska, Marion Stubbs, Adrian L. Harris, Laszlo G. Boros, Madhu Basetti, Dominick J. O. McIntyre, John R. Griffiths
Cells. 2022 Nov; 11(22): 3595. Published online 2022 Nov 14. doi: 10.3390/cells11223595
PMCID:
PMC9688062
AbstractArticlePDF–3.6M

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