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Items: 1 to 20 of 196

1.
Control of nutrient uptake by IRF4 orchestrates innate immune memory
Endi K. Santosa, Hyunu Kim, Timo Rückert, Jean-Benoît Le Luduec, Aamna J. Abbasi, Claire K. Wingert, Lila Peters, Joe N. Frost, Katharine C. Hsu, Chiara Romagnani, Joseph C. Sun
Nat Immunol. Author manuscript; available in PMC 2024 May 16.
Published in final edited form as: Nat Immunol. 2023 Oct; 24(10): 1685–1697. Published online 2023 Sep 11. doi: 10.1038/s41590-023-01620-z
PMCID:
PMC11098052
AbstractArticlePDF–4.9M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Type I interferon activates MHC class I-dressed CD11b+ conventional dendritic cells to promote protective anti-tumor CD8+ T cell immunity
Ellen Duong, Tim B. Fessenden, Emi Lutz, Teresa Dinter, Leon Yim, Sarah Blatt, Arjun Bhutkar, Karl Dane Wittrup, Stefani Spranger
Immunity. Author manuscript; available in PMC 2024 Jan 30.
Published in final edited form as: Immunity. 2022 Feb 8; 55(2): 308–323.e9. Published online 2021 Nov 19. doi: 10.1016/j.immuni.2021.10.020
PMCID:
PMC10827482
AbstractArticlePDF–2.4M
4.
IRF4 affects the protective effect of regulatory T cells on the pulmonary vasculature of a bronchopulmonary dysplasia mouse model by regulating FOXP3
Ying Zhu, Langyue He, Yue Zhu, Huici Yao, Jianfeng Jiang, Hongyan Lu
Mol Med. 2024; 30: 6. Published online 2024 Jan 9. doi: 10.1186/s10020-023-00770-y
PMCID:
PMC10777489
AbstractArticlePDF–3.2M
5.
Pellino 3 promotes the colitis‐associated colorectal cancer through suppression of IRF4‐mediated negative regulation of TLR4 signalling
Young‐Mi Kim, Hye‐Youn Kim, Huyen Trang Ha Thi, Jooyoung Kim, Young Jae Lee, Seong‐Jin Kim, Suntaek Hong
Mol Oncol. 2023 Nov; 17(11): 2380–2395. Published online 2023 Jun 27. doi: 10.1002/1878-0261.13475
PMCID:
PMC10620127
AbstractArticlePDF–2.2M
6.
AIM2 promotes TH17 cells differentiation by regulating RORγt transcription activity
Jefferson Antônio Leite, Luísa Menezes, Eloisa Martins, Tamara Silva Rodrigues, Lucas Tavares, Anna Ebering, Carsten Schelmbauer, Guilherme C. Martelossi Cebinelli, Valeriya Zinina, Artemiy Golden, Natalia Soshnikova, Dario S. Zamboni, Fernando Q. Cunha, Magdalena Huber, João Santana Silva, Ari Waisman, Daniela Carlos, Niels Olsen Saraiva Câmara
iScience. 2023 Nov 17; 26(11): 108134. Published online 2023 Oct 4. doi: 10.1016/j.isci.2023.108134
PMCID:
PMC10585393
AbstractArticlePDF–5.0M
7.
IRF4 is required for migration of CD4+ T cells to the intestine but not for Th2 and Th17 cell maintenance
Constantin Schmidt, Aenne Harberts, Daniel Reimers, Tabea Bertram, Leonie Caroline Voß, Joanna Schmid, Niels Christian Lory, Michael Spohn, Friedrich Koch-Nolte, Samuel Huber, Friederike Raczkowski, Minka Breloer, Hans-Willi Mittrücker
Front Immunol. 2023; 14: 1182502. Published online 2023 Jul 3. doi: 10.3389/fimmu.2023.1182502
PMCID:
PMC10352983
AbstractArticlePDF–11M
8.
A T follicular helper cell origin for T regulatory type 1 cells
Patricia Solé, Jun Yamanouchi, Josep Garnica, Muhammad Myn Uddin, Robert Clarke, Joel Moro, Nahir Garabatos, Shari Thiessen, Mireia Ortega, Santiswarup Singha, Debajyoti Mondal, César Fandos, Julio Saez-Rodriguez, Yang Yang, Pau Serra, Pere Santamaria
Cell Mol Immunol. 2023 May; 20(5): 489–511. Published online 2023 Mar 27. doi: 10.1038/s41423-023-00989-z
PMCID:
PMC10202951
AbstractArticlePDF–13M
9.
IRF4 expression by lung dendritic cells drives acute but not Trm cell–dependent memory Th2 responses
Daniel F. Camacho, Tania E. Velez, Maile K. Hollinger, Esther Wang, Chanie L. Howard, Eli P. Darnell, Domenick E. Kennedy, Paulette A. Krishack, Cara L. Hrusch, Marcus R. Clark, James J. Moon, Anne I. Sperling
JCI Insight. 2022 Nov 8; 7(21): e140384. Published online 2022 Nov 8. doi: 10.1172/jci.insight.140384
PMCID:
PMC9675458
AbstractArticlePDF–4.3M
10.
IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity
Dennis Das Gupta, Christoph Paul, Nadine Samel, Maria Bieringer, Daniel Staudenraus, Federico Marini, Hartmann Raifer, Lisa Menke, Lea Hansal, Bärbel Camara, Edith Roth, Patrick Daum, Michael Wanzel, Marco Mernberger, Andrea Nist, Uta-Maria Bauer, Frederik Helmprobst, Malte Buchholz, Katrin Roth, Lorenz Bastian, Alina M. Hartmann, Claudia Baldus, Koichi Ikuta, Andreas Neubauer, Andreas Burchert, Hans-Martin Jäck, Matthias Klein, Tobias Bopp, Thorsten Stiewe, Axel Pagenstecher, Michael Lohoff
Cell Death Differ. 2022 Nov; 29(11): 2163–2176. Published online 2022 Apr 22. doi: 10.1038/s41418-022-01005-z
PMCID:
PMC9613660
AbstractArticlePDF–5.8M
11.
Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B-cell response
Qianwen Hu, Tingting Xu, Min Zhang, Heng Zhang, Yongbo Liu, Hua-bing Li, Chiqi Chen, Junke Zheng, Zhen Zhang, Fubin Li, Nan Shen, Wenqian Zhang, Ari Melnick, Chuanxin Huang
Cell Rep. Author manuscript; available in PMC 2022 Oct 10.
Published in final edited form as: Cell Rep. 2022 Jul 5; 40(1): 111035. doi: 10.1016/j.celrep.2022.111035
PMCID:
PMC9550188
AbstractArticlePDF–971K
12.
Jmjd3/IRF4 axis aggravates myeloid fibroblast activation and m2 macrophage to myofibroblast transition in renal fibrosis
Hua Liang, Benquan Liu, Ying Gao, Jiayi Nie, Shuyun Feng, Wenqiang Yu, Shihong Wen, Xi Su
Front Immunol. 2022; 13: 978262. Published online 2022 Sep 8. doi: 10.3389/fimmu.2022.978262
PMCID:
PMC9494509
AbstractArticlePDF–7.4M
13.
Regulation of microglial activation in stroke in aged mice: a translational study
Conelius Ngwa, Abdullah Al Mamun, Shaohua Qi, Romana Sharmeen, Yan Xu, Fudong Liu
Aging (Albany NY) 2022 Aug 15; 14(15): 6047–6065. Published online 2022 Aug 12. doi: 10.18632/aging.204216
PMCID:
PMC9417226
AbstractArticlePDF–1.7M
14.
CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells
Dan Liu, Lihui Duan, Lauren B Rodda, Erick Lu, Ying Xu, Jinping An, Longhui Qiu, Fengchun Liu, Mark R Looney, Zhiyong Yang, Christopher D C Allen, Zhongmei Li, Alexander Marson, Jason G Cyster
Science. Author manuscript; available in PMC 2023 Feb 11.
Published in final edited form as: Science. 2022 Feb 11; 375(6581): eabi5965. Published online 2022 Feb 11. doi: 10.1126/science.abi5965
PMCID:
PMC9310086
AbstractArticlePDF–2.9M
15.
Expression levels of cellular inhibitor of apoptosis proteins and colitogenic cytokines are inversely correlated with the activation of interferon regulatory factor 4
Sho Masaki, Tomohiro Watanabe, Yasuyuki Arai, Ikue Sekai, Akane Hara, Masayuki Kurimoto, Yasuo Otsuka, Yasuhiro Masuta, Tomoe Yoshikawa, Ryutaro Takada, Ken Kamata, Kosuke Minaga, Kouhei Yamashita, Masatoshi Kudo
Clin Exp Immunol. 2022 Mar; 207(3): 340–350. Published online 2022 Jan 17. doi: 10.1093/cei/uxac005
PMCID:
PMC9113101
AbstractArticlePDF–1.9M
16.
The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming
Sophia M. Hochrein, Hao Wu, Miriam Eckstein, Laura Arrigoni, Josip S. Herman, Fabian Schumacher, Christian Gerecke, Mathias Rosenfeldt, Dominic Grün, Burkhard Kleuser, Georg Gasteiger, Wolfgang Kastenmüller, Bart Ghesquière, Jan Van den Bossche, E. Dale Abel, Martin Vaeth
Cell Metab. Author manuscript; available in PMC 2023 Apr 5.
Published in final edited form as: Cell Metab. 2022 Apr 5; 34(4): 516–532.e11. Published online 2022 Mar 21. doi: 10.1016/j.cmet.2022.02.015
PMCID:
PMC9019065
AbstractArticlePDF–1.8M
17.
Macrophage interferon regulatory factor 4 deletion ameliorates aristolochic acid nephropathy via reduced migration and increased apoptosis
Kensuke Sasaki, Andrew S. Terker, Jiaqi Tang, Shirong Cao, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Stephanie R. Bennett, Ming-zhi Zhang, Raymond C. Harris
JCI Insight. 2022 Feb 22; 7(4): e150723. Published online 2022 Feb 22. doi: 10.1172/jci.insight.150723
PMCID:
PMC8876461
AbstractArticlePDF–11M
18.
Granulocyte Macrophage-Colony Stimulating Factor Produces a Splenic Subset of Monocyte-Derived Dendritic Cells That Efficiently Polarize T Helper Type 2 Cells in Response to Blood-Borne Antigen
Seul Hye Ryu, Hyun Soo Shin, Hye Hyeon Eum, Ji Soo Park, Wanho Choi, Hye Young Na, Hyunju In, Tae-Gyun Kim, Sejung Park, Soomin Hwang, Moah Sohn, Eun-Do Kim, Kyoung Yul Seo, Hae-Ock Lee, Min-Geol Lee, Min Kyung Chu, Chae Gyu Park
Front Immunol. 2021; 12: 767037. Published online 2022 Jan 3. doi: 10.3389/fimmu.2021.767037
PMCID:
PMC8778578
AbstractArticlePDF–11M
19.
IRF4 Has a Unique Role in Early B Cell Development and Acts Prior to CD21 Expression to Control Marginal Zone B Cell Numbers
Kristina Ottens, Anne B. Satterthwaite
Front Immunol. 2021; 12: 779085. Published online 2021 Nov 22. doi: 10.3389/fimmu.2021.779085
PMCID:
PMC8645892
AbstractArticlePDF–3.2M
20.
Selective depletion of a CD64-expressing phagocyte subset mediates protection against toxic kidney injury and failure
Natallia Salei, Xingqi Ji, Dalia Pakalniškytė, Vanessa Kuentzel, Stephan Rambichler, Na Li, Markus Moser, Katja Steiger, Thorsten Buch, Hans-Joachim Anders, Barbara U. Schraml
Proc Natl Acad Sci U S A. 2021 Sep 28; 118(39): e2022311118. Published online 2021 Sep 13. doi: 10.1073/pnas.2022311118
PMCID:
PMC8488624
AbstractArticlePDF–1.8M

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