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Select item 76447251.

Defective minor spliceosomes induce SMA-associated phenotypes through sensitive intron-containing neural genes in Drosophila

Liang Li, Zhan Ding, Ting-Lin Pang, Bei Zhang, Chen-Hui Li, An-Min Liang, Yu-Ru Wang, Yu Zhou, Yu-Jie Fan, Yong-Zhen Xu

Nat Commun. 2020; 11: 5608. Published online 2020 Nov 5. doi: 10.1038/s41467-020-19451-z

PMCID:: PMC7644725

Abstract Article PDF–3.0M

Select item 69615782.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 59891573.

An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio

Wei-Hsiang Lin, Miaomiao He, Yuen Ngan Fan, Richard A. Baines

J Neurogenet. 2018; 32(2): 106–117. Published online 2018 May 2. doi: 10.1080/01677063.2018.1465570

PMCID:: PMC5989157

Abstract Article PDF–1.5M

Select item 57078054.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890025.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 48293176.

Genome-wide identification and characterization of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing

Alborz Mazloomian, Irmtraud M Meyer

RNA Biol. 2015 Dec; 12(12): 1391–1401. Published online 2015 Oct 29. doi: 10.1080/15476286.2015.1107703

PMCID:: PMC4829317

Abstract Article PDF–609K

Select item 45706977.

Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach

Flavio Pazos Obregón, Cecilia Papalardo, Sebastián Castro, Gustavo Guerberoff, Rafael Cantera

BMC Genomics. 2015; 16(1): 694. Published online 2015 Sep 15. doi: 10.1186/s12864-015-1888-3

PMCID:: PMC4570697

Abstract Article PDF–2.0M

Select item 45283308.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 45283299.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 440266310.

Identification of Genes Associated with Resilience/Vulnerability to Sleep Deprivation and Starvation in Drosophila

Matthew S. Thimgan, Laurent Seugnet, John Turk, Paul J. Shaw

Sleep. 2015 May 1; 38(5): 801–814. Published online 2015 May 1. doi: 10.5665/sleep.4680

PMCID:: PMC4402663

Abstract Article PDF–1.4M

Select item 435973811.

Changes in organelle position and epithelial architecture associated with loss of CrebA

Rebecca M. Fox, Deborah J. Andrew

Biol Open. 2015 Mar 15; 4(3): 317–330. Published online 2015 Feb 13. doi: 10.1242/bio.201411205

PMCID:: PMC4359738

Abstract Article PDF–2.2M

Select item 435288712.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 427152713.

Phylostratigraphic Bias Creates Spurious Patterns of Genome Evolution

Bryan A. Moyers, Jianzhi Zhang

Mol Biol Evol. 2015 Jan 1; 32(1): 258–267. Published online 2014 Oct 13. doi: 10.1093/molbev/msu286

Correction in:: Mol Biol Evol. 2016 Nov; 33(11): 3031.

PMCID:: PMC4271527

Abstract Article PDF–618K

Select item 385171814.

Developmental arrest of Drosophila survival motor neuron (Smn) mutants accounts for differences in expression of minor intron-containing genes

Eric L. Garcia, Zhipeng Lu, Michael P. Meers, Kavita Praveen, A. Gregory Matera

RNA. 2013 Nov; 19(11): 1510–1516. doi: 10.1261/rna.038919.113

PMCID:: PMC3851718

Abstract Article PDF–410K

Select item 353067715.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 347459616.

A SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function

Francesco Lotti, Wendy L. Imlach, Luciano Saieva, Erin S. Beck, Le T. Hao, Darrick K. Li, Wei Jiao, George Z. Mentis, Christine E. Beattie, Brian D. McCabe, Livio Pellizzoni

Cell. Author manuscript; available in PMC 2013 Oct 12.

Published in final edited form as: Cell. 2012 Oct 12; 151(2): 440–454. doi: 10.1016/j.cell.2012.09.012

PMCID:: PMC3474596

Abstract Article PDF–3.8M

Select item 346946717.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 340590118.

A Drosophila model of Spinal Muscular Atrophy uncouples the snRNP biogenesis functions of survival motor neuron from locomotion and viability defects

Kavita Praveen, Ying Wen, A. Gregory Matera

Cell Rep. Author manuscript; available in PMC 2012 Jul 26.

Published in final edited form as: Cell Rep. 2012 Jun 28; 1(6): 624–631. Published online 2012 Jun 21. doi: 10.1016/j.celrep.2012.05.014

PMCID:: PMC3405901

Abstract Article PDF–1.0M

Select item 304044119.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

Select item 295259820.

Gene Expression Profiling of U12-Type Spliceosome Mutant Drosophila Reveals Widespread Changes in Metabolic Pathways

Heli K. J. Pessa, Dario Greco, Jouni Kvist, Gudrun Wahlström, Tapio I. Heino, Petri Auvinen, Mikko J. Frilander

PLoS One. 2010; 5(10): e13215. Published online 2010 Oct 11. doi: 10.1371/journal.pone.0013215

PMCID:: PMC2952598

Abstract Article PDF–2.5M

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