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Items: 1 to 20 of 29

1.
Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC
Tom Snelling, Natalia Shpiro, Robert Gourlay, Frederic Lamoliatte, Philip Cohen
Biochem J. 2022 Oct 28; 479(20): 2195–2216. Published online 2022 Oct 21. doi: 10.1042/BCJ20220401
PMCID:
PMC9704527
AbstractArticlePDF–7.7M
2.
TIFA promotes colorectal cancer cell proliferation in an RSK‐ and PRAS40‐dependent manner
Wenzhi Shen, Wenfei Du, Yanping Li, Yongming Huang, Xinyu Jiang, Chenglong Yang, Jiaping Tang, Huan Liu, Na Luo, Xiaoyuan Zhang, Zhixin Zhang
Cancer Sci. 2022 Sep; 113(9): 3018–3031. Published online 2022 Jun 14. doi: 10.1111/cas.15432
PMCID:
PMC9459298
AbstractArticlePDF–13M
3.
A20 undermines alternative NF-κB activity and expression of anti-apoptotic genes in Helicobacter pylori infection
Michelle C. C. Lim, Gunter Maubach, Anna M. Birkl-Toeglhofer, Johannes Haybaeck, Michael Vieth, Mchael Naumann
Cell Mol Life Sci. 2022 Feb; 79(2): 102. Published online 2022 Jan 28. doi: 10.1007/s00018-022-04139-y
PMCID:
PMC8799570
AbstractArticlePDF–2.3M
4.
TIFA has dual functions in Helicobacter pylori‐induced classical and alternative NF‐κB pathways
Gunter Maubach, Michelle C C Lim, Olga Sokolova, Steffen Backert, Thomas F Meyer, Michael Naumann
EMBO Rep. 2021 Sep 6; 22(9): e52878. Published online 2021 Jul 30. doi: 10.15252/embr.202152878
PMCID:
PMC8419686
AbstractArticlePDF–3.8M
5.
TIFA protein expression is associated with pulmonary arterial hypertension
Hao-Chih Chang, Tong-You Wade Wei, Pei-Yu Wu, Ming-Daw Tsai, Wen-Chung Yu, Chen-Huan Chen, Shih-Hsien Sung
Sci Rep. 2021; 11: 14140. Published online 2021 Jul 8. doi: 10.1038/s41598-021-93582-1
PMCID:
PMC8266829
AbstractArticlePDF–1.4M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress
Michael Bauer, Zuzana Nascakova, Anca-Irina Mihai, Phil F. Cheng, Mitchell P. Levesque, Simon Lampart, Robert Hurwitz, Lennart Pfannkuch, Jana Dobrovolna, Melanie Jacobs, Sina Bartfeld, Anders Dohlman, Xiling Shen, Alevtina A. Gall, Nina R. Salama, Antonia Töpfer, Achim Weber, Thomas F. Meyer, Pavel Janscak, Anne Müller
Nat Commun. 2020; 11: 5117. Published online 2020 Oct 9. doi: 10.1038/s41467-020-18857-z
PMCID:
PMC7547021
AbstractArticlePDF–5.6M
8.
TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis
Madeline Niederkorn, Kathleen Hueneman, Kwangmin Choi, Melinda E. Varney, Laurel Romano, Mario A. Pujato, Kenneth D. Greis, Jun-ichiro Inoue, Ruhikanta Meetei, Daniel T. Starczynowski
Cell Rep. Author manuscript; available in PMC 2020 Jul 27.
Published in final edited form as: Cell Rep. 2020 Feb 25; 30(8): 2776–2790.e6. doi: 10.1016/j.celrep.2020.01.093
PMCID:
PMC7384867
AbstractArticlePDF–2.2M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
11.
TRAF-interacting protein with forkhead-associated domain (TIFA) transduces DNA damage–induced activation of NF-κB
Jingxuan Fu, Daoyuan Huang, Fuwen Yuan, Nan Xie, Qian Li, Xinpei Sun, Xuehong Zhou, Guodong Li, Tanjun Tong, Yu Zhang
J Biol Chem. 2018 May 11; 293(19): 7268–7280. Published online 2018 Mar 26. doi: 10.1074/jbc.RA117.001684
PMCID:
PMC5950011
AbstractArticlePDF–2.0M
12.
TIFA suppresses hepatocellular carcinoma progression via MALT1-dependent and -independent signaling pathways
Wenzhi Shen, Renle Du, Jun Li, Xiaohe Luo, Shuangtao Zhao, Antao Chang, Wei Zhou, Ruifang Gao, Dehong Luo, Juan Wang, Na Hao, Yanhua Liu, Yanan Chen, Yunping Luo, Peiqing Sun, Shengyong Yang, Na Luo, Rong Xiang
Signal Transduct Target Ther. 2016; 1: 16013. Published online 2016 Jul 22. doi: 10.1038/sigtrans.2016.13
PMCID:
PMC5661659
AbstractArticlePDF–5.5M
13.
TIFA Signaling in Gastric Epithelial Cells Initiates the cag Type 4 Secretion System-Dependent Innate Immune Response to Helicobacter pylori Infection
Alevtina Gall, Ryan G. Gaudet, Scott D. Gray-Owen, Nina R. Salama
mBio. 2017 Jul-Aug; 8(4): e01168-17. Published online 2017 Aug 15. doi: 10.1128/mBio.01168-17
PMCID:
PMC5559637
AbstractArticlePDF–2.1M
14.
Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis
Saskia C. Stein, Eugenia Faber, Simon H. Bats, Tatiana Murillo, Yvonne Speidel, Nina Coombs, Christine Josenhans
PLoS Pathog. 2017 Jul; 13(7): e1006514. Published online 2017 Jul 17. doi: 10.1371/journal.ppat.1006514
PMCID:
PMC5531669
AbstractArticlePDF–6.5M
15.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
16.
ALPK1 controls TIFA/TRAF6-dependent innate immunity against heptose-1,7-bisphosphate of gram-negative bacteria
Milica Milivojevic, Anne-Sophie Dangeard, Christoph Alexander Kasper, Therese Tschon, Mario Emmenlauer, Claudine Pique, Pamela Schnupf, Julie Guignot, Cécile Arrieumerlou
PLoS Pathog. 2017 Feb; 13(2): e1006224. Published online 2017 Feb 21. doi: 10.1371/journal.ppat.1006224
PMCID:
PMC5336308
AbstractArticlePDF–3.1M
17.
TIFA as a crucial mediator for NLRP3 inflammasome
Ting-Yang Lin, Tong-You Wade Wei, Shuai Li, Shen-Chih Wang, Ming He, Marcy Martin, Jiao Zhang, Tzu-Pin Shentu, Han Xiao, Jian Kang, Kuei-Chun Wang, Zhen Chen, Shu Chien, Ming-Daw Tsai, John Y.-J. Shyy
Proc Natl Acad Sci U S A. 2016 Dec 27; 113(52): 15078–15083. Published online 2016 Dec 13. doi: 10.1073/pnas.1618773114
PMCID:
PMC5206521
AbstractArticlePDF–1011K
18.
O-linked N-acetylglucosamine transferase (OGT) interacts with the histone chaperone HIRA complex and regulates nucleosome assembly and cellular senescence
Jong-Sun Lee, Zhiguo Zhang
Proc Natl Acad Sci U S A. 2016 Jun 7; 113(23): E3213–E3220. Published online 2016 May 23. doi: 10.1073/pnas.1600509113
PMCID:
PMC4988580
AbstractArticlePDF–1.4M
19.
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics
Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth
Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660
PMCID:
PMC4848762
AbstractArticlePDF–2.8M
20.
An inter‐species protein–protein interaction network across vast evolutionary distance
Quan Zhong, Samuel J Pevzner, Tong Hao, Yang Wang, Roberto Mosca, Jörg Menche, Mikko Taipale, Murat Taşan, Changyu Fan, Xinping Yang, Patrick Haley, Ryan R Murray, Flora Mer, Fana Gebreab, Stanley Tam, Andrew MacWilliams, Amélie Dricot, Patrick Reichert, Balaji Santhanam, Lila Ghamsari, Michael A Calderwood, Thomas Rolland, Benoit Charloteaux, Susan Lindquist, Albert‐László Barabási, David E Hill, Patrick Aloy, Michael E Cusick, Yu Xia, Frederick P Roth, Marc Vidal
Mol Syst Biol. 2016 Apr; 12(4): 865. Published online 2016 Apr 23. doi: 10.15252/msb.20156484
PMCID:
PMC4848758
AbstractArticlePDF–2.1M

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