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Select item 111900621.

Toll-like receptor signaling in multiple myeloma cells promotes the expression of pro-survival genes B-cell lymphoma 2 and MYC and modulates the expression of B-cell maturation antigen

Synne Stokke Tryggestad, Ingrid Aass Roseth, Kristin Roseth Aass, Nadia Elise Helene Ørning, Robin Mjelle, Hanne Hella, Therese Standal

Front Immunol. 2024; 15: 1393906. Published online 2024 Jun 7. doi: 10.3389/fimmu.2024.1393906

PMCID:: PMC11190062

Abstract Article PDF–2.5M

Select item 111127992.

BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma

Qizhong Lu, Hexian Li, Zhiguo Wu, Zhixiong Zhu, Zongliang Zhang, Donghui Yang, Aiping Tong

J Nanobiotechnology. 2024; 22: 279. Published online 2024 May 23. doi: 10.1186/s12951-024-02512-6

PMCID:: PMC11112799

Abstract Article PDF–7.7M

Select item 110341163.

25-hydroxycholesterol promotes proliferation and metastasis of lung adenocarcinoma cells by regulating ERβ/TNFRSF17 axis

Mengting He, Wenbo Jiang, Xingkai Li, Hongjin Liu, Hongsheng Ren, Yanliang Lin

BMC Cancer. 2024; 24: 505. Published online 2024 Apr 22. doi: 10.1186/s12885-024-12227-4

PMCID:: PMC11034116

Abstract Article PDF–25M

Select item 110285304.

Immunogenicity of dendritic cells pulsed with MAGE3, Survivin and B-cell maturation antigen mRNA for vaccination of multiple myeloma patients

Willemijn Hobo, Leonie Strobbe, Frans Maas, Hanny Fredrix, Annelies Greupink-Draaisma, Ben Esendam, Theo de Witte, Frank Preijers, Henriëtte Levenga, Bas van Rees, Reinier Raymakers, Nicolaas Schaap, Harry Dolstra

Cancer Immunol Immunother. 2013 Aug; 62(8): 1381–1392. Published online 2013 Jun 2. doi: 10.1007/s00262-013-1438-2

PMCID:: PMC11028530

Abstract Article PDF–335K

Select item 101780675.

Soluble B-cell maturation antigen as a monitoring marker for multiple myeloma

Ádám Wiedemann, Virág Réka Szita, Róbert Horváth, Attila Szederjesi, Attila Sebő, András Dávid Tóth, Tamás Masszi, Gergely Varga

Pathol Oncol Res. 2023; 29: 1611171. Published online 2023 Apr 28. doi: 10.3389/pore.2023.1611171

PMCID:: PMC10178067

Abstract Article PDF–1.5M

Select item 87527226.

A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers

Derek P. Wong, Nand K. Roy, Keman Zhang, Anusha Anukanth, Abhishek Asthana, Nicole J. Shirkey-Son, Samantha Dunmire, Bryan J. Jones, Walker S. Lahr, Beau R. Webber, Branden S. Moriarity, Paolo Caimi, Reshmi Parameswaran

Nat Commun. 2022; 13: 217. Published online 2022 Jan 11. doi: 10.1038/s41467-021-27853-w

PMCID:: PMC8752722

Abstract Article PDF–3.6M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76003808.

Anti-BCMA Immunotoxins: Design, Production, and Preclinical Evaluation

Tapan K. Bera

Biomolecules. 2020 Oct; 10(10): 1387. Published online 2020 Sep 29. doi: 10.3390/biom10101387

PMCID:: PMC7600380

Abstract Article PDF–1.6M

Select item 75668819.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 732705110.

B-cell maturation antigen expression across hematologic cancers: a systematic literature review

Ahmet Dogan, David Siegel, Nguyet Tran, Alan Fu, Jessica Fowler, Rajesh Belani, Ola Landgren

Blood Cancer J. 2020 Jun; 10(6): 73. Published online 2020 Jun 30. doi: 10.1038/s41408-020-0337-y

PMCID:: PMC7327051

Abstract Article PDF–614K

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 714831912.

Analysis of the receptor BCMA as a biomarker in systemic lupus erythematosus patients

Diana Celeste Salazar-Camarena, Claudia Azucena Palafox-Sánchez, Alvaro Cruz, Miguel Marín-Rosales, José Francisco Muñoz-Valle

Sci Rep. 2020; 10: 6236. Published online 2020 Apr 10. doi: 10.1038/s41598-020-63390-0

PMCID:: PMC7148319

Abstract Article PDF–3.1M

Select item 672822113.

Selective Targeting of Multiple Myeloma by B cell Maturation Antigen (BCMA)-specific Central Memory CD8⁺ Cytotoxic T Lymphocytes: Immunotherapeutic Application in Vaccination and Adoptive Immunotherapy

Jooeun Bae, Mehmet Samur, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson

Leukemia. Author manuscript; available in PMC 2019 Sep 5.

Published in final edited form as: Leukemia. 2019 Sep; 33(9): 2208–2226. Published online 2019 Mar 12. doi: 10.1038/s41375-019-0414-z

PMCID:: PMC6728221

Abstract Article PDF–5.1M

Select item 593094614.

Effective Targeting of Multiple B-Cell Maturation Antigen–Expressing Hematological Malignances by Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor T Cells

Kevin M. Friedman, Tracy E. Garrett, John W. Evans, Holly M. Horton, Howard J. Latimer, Stacie L. Seidel, Christopher J. Horvath, Richard A. Morgan

Hum Gene Ther. 2018 May 1; 29(5): 585–601. Published online 2018 May 1. doi: 10.1089/hum.2018.001

PMCID:: PMC5930946

Abstract Article PDF–1.8M

Select item 571617615.

Soluble TACI and soluble BCMA as biomarkers in primary central nervous system lymphoma

Franziska S Thaler, Sarah A Laurent, Marion Huber, Matthias Mulazzani, Martin Dreyling, Uwe Ködel, Tania Kümpfel, Andreas Straube, Edgar Meinl, Louisa von Baumgarten

Neuro Oncol. 2017 Nov; 19(12): 1618–1627. Published online 2017 May 17. doi: 10.1093/neuonc/nox097

PMCID:: PMC5716176

Abstract Article PDF–2.3M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 539511917.

Serum B-cell maturation antigen: a novel biomarker to predict outcomes for multiple myeloma patients

Michael Ghermezi, Mingjie Li, Suzie Vardanyan, Nika Manik Harutyunyan, Jillian Gottlieb, Ariana Berenson, Tanya M. Spektor, Claudia Andreu-Vieyra, Sophia Petraki, Eric Sanchez, Kyle Udd, Cathy S. Wang, Regina A. Swift, Haiming Chen, James R. Berenson

Haematologica. 2017 Apr; 102(4): 785–795. Prepublished online 2016 Dec 29. doi: 10.3324/haematol.2016.150896

PMCID:: PMC5395119

Abstract Article PDF–1.1M

Select item 492002318.

APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment

Yu-Tzu Tai, Chirag Acharya, Gang An, Michele Moschetta, Mike Y. Zhong, Xiaoyan Feng, Michele Cea, Antonia Cagnetta, Kenneth Wen, Hans van Eenennaam, Andrea van Elsas, Lugui Qiu, Paul Richardson, Nikhil Munshi, Kenneth C. Anderson

Blood. 2016 Jun 23; 127(25): 3225–3236. Prepublished online 2016 Apr 28. doi: 10.1182/blood-2016-01-691162

PMCID:: PMC4920023

Abstract Article

Select item 460562719.

Detection of The TNFSF Members BAFF, APRIL, TWEAK and Their Receptors in Normal Kidney and Renal Cell Carcinomas

Vassiliki Pelekanou, George Notas, Katerina Theodoropoulou, Marilena Kampa, Dimitrios Takos, Vassilia-Ismini Alexaki, Jelena Radojicic, Frank Sofras, Andreas Tsapis, Efstathios N. Stathopoulos, Elias Castanas

Anal Cell Pathol (Amst) 2011; 34(1-2): 49–60. Published online 2011 Feb 28. doi: 10.3233/ACP-2011-0001

PMCID:: PMC4605627

Abstract PDF–1.7M

Select item 449056520.

γ-secretase directly sheds the survival receptor BCMA from plasma cells

Sarah A. Laurent, Franziska S. Hoffmann, Peer-Hendrik Kuhn, Qingyu Cheng, Yuanyuan Chu, Marc Schmidt-Supprian, Stefanie M. Hauck, Elisabeth Schuh, Markus Krumbholz, Heike Rübsamen, Johanna Wanngren, Mohsen Khademi, Tomas Olsson, Tobias Alexander, Falk Hiepe, Hans-Walter Pfister, Frank Weber, Dieter Jenne, Hartmut Wekerle, Reinhard Hohlfeld, Stefan F. Lichtenthaler, Edgar Meinl

Nat Commun. 2015; 6: 7333. Published online 2015 Jun 11. doi: 10.1038/ncomms8333

PMCID:: PMC4490565

Abstract Article PDF–1.3M

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