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Items: 1 to 20 of 28

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
One-carbon metabolism is required for epigenetic stability in the mouse placenta
Claire E. Senner, Ziqi Dong, Malwina Prater, Miguel R. Branco, Erica D. Watson
Front Cell Dev Biol. 2023; 11: 1209928. Published online 2023 Jun 27. doi: 10.3389/fcell.2023.1209928
PMCID:
PMC10333575
AbstractArticlePDF–3.2M
3.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
4.
Disruption of Folate Metabolism Causes Poor Alignment and Spacing of Mouse Conceptuses for Multiple Generations
Amy L. Wilkinson, Katerina Menelaou, Joanna Rakoczy, Xiu S. Tan, Erica D. Watson
Front Cell Dev Biol. 2021; 9: 723978. Published online 2021 Dec 10. doi: 10.3389/fcell.2021.723978
PMCID:
PMC8703036
AbstractArticlePDF–6.2M
5.
Liver and brain differential expression of one-carbon metabolism genes during ontogenesis
Apolline Imbard, Leslie Schwendimann, Sophie Lebon, Pierre Gressens, Henk J. Blom, Jean-François Benoist
Sci Rep. 2021; 11: 21132. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00311-9
PMCID:
PMC8548596
AbstractArticlePDF–1.3M
6.
Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker
Georgina E. T. Blake, Xiaohui Zhao, Hong wa Yung, Graham J. Burton, Anne C. Ferguson-Smith, Russell S. Hamilton, Erica D. Watson
Nat Commun. 2021; 12: 3714. Published online 2021 Jun 17. doi: 10.1038/s41467-021-24036-5
PMCID:
PMC8211854
AbstractArticlePDF–1.9M
7.
Variably methylated retrotransposons are refractory to a range of environmental perturbations
Tessa M. Bertozzi, Jessica L. Becker, Georgina E.T. Blake, Amita Bansal, Duy K. Nguyen, Denise S. Fernandez-Twinn, Susan E. Ozanne, Marisa S. Bartolomei, Rebecca A. Simmons, Erica D. Watson, Anne C. Ferguson-Smith
Nat Genet. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: Nat Genet. 2021 Aug 1; 53(8): 1233–1242. Published online 2021 Jul 29. doi: 10.1038/s41588-021-00898-9
PMCID:
PMC7611517
AbstractArticlePDF–3.1M
8.
Analysis of spermatogenesis and fertility in adult mice with a hypomorphic mutation in the Mtrr gene
Georgina E.T. Blake, Jessica Hall, Grace E. Petkovic, Erica D. Watson
Reprod Fertil Dev. Author manuscript; available in PMC 2020 Nov 13.
Published in final edited form as: Reprod Fertil Dev. 2019 Oct 1; 31(11): 1730–1741. doi: 10.1071/RD19064
PMCID:
PMC7116358
AbstractArticlePDF–1.8M
9.
Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice
Alice P. Sowton, Nisha Padmanabhan, Simon J. Tunster, Ben D. McNally, Antonio Murgia, Aisha Yusuf, Julian L. Griffin, Andrew J. Murray, Erica D. Watson
Mol Genet Metab Rep. 2020 Jun; 23: 100580. Published online 2020 Mar 24. doi: 10.1016/j.ymgmr.2020.100580
PMCID:
PMC7109458
AbstractArticlePDF–2.0M
10.
Abnormal folate metabolism causes age‐, sex‐ and parent‐of‐origin‐specific haematological defects in mice
Nisha Padmanabhan, Katerina Menelaou, Jiali Gao, Alexander Anderson, Georgina E. T. Blake, Tanya Li, B. Nuala Daw, Erica D. Watson
J Physiol. 2018 Sep 15; 596(18): 4341–4360. Published online 2018 Aug 15. doi: 10.1113/JP276419
PMCID:
PMC6138292
AbstractArticlePDF–1.8M
11.
Multigenerational analysis of sex-specific phenotypic differences at midgestation caused by abnormal folate metabolism
Nisha Padmanabhan, Joanna Rakoczy, Monika Kondratowicz, Katerina Menelaou, Georgina E T Blake, Erica D Watson
Environ Epigenet. 2017 Oct; 3(4): dvx014. Published online 2017 Nov 3. doi: 10.1093/eep/dvx014
PMCID:
PMC5804557
AbstractArticlePDF–1001K
12.
Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2
Paul A. Dutchak, Sunil Laxman, Sandi Jo Estill, Chensu Wang, Yun Wang, Yiguang Wang, Gamze B. Bulut, Jinming Gao, Lily J. Huang, Benjamin P. Tu
Cell Rep. Author manuscript; available in PMC 2016 Jul 21.
Published in final edited form as: Cell Rep. 2015 Jul 21; 12(3): 371–379. Published online 2015 Jul 9. doi: 10.1016/j.celrep.2015.06.042
PMCID:
PMC4830278
AbstractArticlePDF–1.4M
13.
Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice
Luz D. Orozco, Marco Morselli, Liudmilla Rubbi, Weilong Guo, James Go, Huwenbo Shi, David Lopez, Nicholas A Furlotte, Brian J Bennett, Charles R Farber, Anatole Ghazalpour, Michael Q Zhang, Renata Bahous, Rima Rozen, Aldons J Lusis, Matteo Pellegrini
Cell Metab. Author manuscript; available in PMC 2016 Jun 2.
Published in final edited form as: Cell Metab. 2015 Jun 2; 21(6): 905–917. doi: 10.1016/j.cmet.2015.04.025
PMCID:
PMC4454894
AbstractArticlePDF–4.0M
14.
Mutation in Folate Metabolism Causes Epigenetic Instability and Transgenerational Effects On Development
Nisha Padmanabhan, Dongxin Jia, Colleen Geary-Joo, Xuchu Wu, Anne C. Ferguson-Smith, Ernest Fung, Mark C. Bieda, Floyd F. Snyder, Roy A. Gravel, James C. Cross, Erica D. Watson
Cell. Author manuscript; available in PMC 2014 Sep 26.
Published in final edited form as: Cell. 2013 Sep 26; 155(1): 10.1016/j.cell.2013.09.002. doi: 10.1016/j.cell.2013.09.002
PMCID:
PMC3844871
AbstractArticlePDF–7.0M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Methionine synthase reductase deficiency results in adverse reproductive outcomes and congenital heart defects in mice
Liyuan Deng, C. Lee Elmore, Andrea K. Lawrance, Rowena G. Matthews, Rima Rozen
Mol Genet Metab. Author manuscript; available in PMC 2011 Jun 8.
Published in final edited form as: Mol Genet Metab. 2008 Jul; 94(3): 336–342. Published online 2008 Apr 14. doi: 10.1016/j.ymgme.2008.03.004
PMCID:
PMC3110750
AbstractArticlePDF–743K
18.
Restricted Role for Methionine Synthase Reductase Defined by Subcellular Localization
DS Froese, X Wu, J Zhang, R Dumas, WM Schoel, M Amrein, RA Gravel
Mol Genet Metab. Author manuscript; available in PMC 2009 Oct 21.
Published in final edited form as: Mol Genet Metab. 2008 May; 94(1): 68–77. Published online 2008 Jan 24. doi: 10.1016/j.ymgme.2007.11.019
PMCID:
PMC2765244
AbstractArticlePDF–1.0M
19.
The Level of the Transcription Factor Pax6 Is Essential for Controlling the Balance between Neural Stem Cell Self-Renewal and Neurogenesis
Stephen N. Sansom, Dean S. Griffiths, Andrea Faedo, Dirk-Jan Kleinjan, Youlin Ruan, James Smith, Veronica van Heyningen, John L. Rubenstein, Frederick J. Livesey
PLoS Genet. 2009 Jun; 5(6): e1000511. Published online 2009 Jun 12. doi: 10.1371/journal.pgen.1000511
PMCID:
PMC2686252
AbstractArticlePDF–4.5M
20.
Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1α
Siming Li, Erland Arning, Chang Liu, Victor Vitvitsky, Carlos Hernandez, Ruma Banerjee, Teodoro Bottiglieri, Jiandie D. Lin
Am J Physiol Endocrinol Metab. 2009 Mar; 296(3): E543–E548. Published online 2009 Jan 21. doi: 10.1152/ajpendo.90719.2008
PMCID:
PMC2660144
AbstractArticle

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