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Select item 110379291.

Identifying potential dietary treatments for inherited metabolic disorders using Drosophila nutrigenomics

Felipe Martelli, Jiayi Lin, Sarah Mele, Wendy Imlach, Oguz Kanca, Christopher K. Barlow, Jefferson Paril, Ralf B. Schittenhelm, John Christodoulou, Hugo J. Bellen, Matthew D.W. Piper, Travis K. Johnson

Cell Rep. Author manuscript; available in PMC 2024 Apr 23.

Published in final edited form as: Cell Rep. 2024 Mar 26; 43(3): 113861. Published online 2024 Feb 27. doi: 10.1016/j.celrep.2024.113861

PMCID:: PMC11037929

Abstract Article PDF–1.9M

Select item 108258852.

Large analysis of genetic manipulations reveals an inverse correlation between initial alcohol resistance and rapid tolerance phenotypes

Maggie M. Chvilicek, Alexandra Seguin, Daniel R. Lathen, Iris Titos, Pearl N. Cummins‐Beebee, Miguel A. Pabon, Maša Miščević, Emily Nickel, Collin B. Merrill, Aylin R. Rodan, Adrian Rothenfluh

Genes Brain Behav. 2024 Feb; 23(1): e12884. Published online 2024 Jan 30. doi: 10.1111/gbb.12884

PMCID:: PMC10825885

Abstract Article PDF–1.7M

Select item 102131993.

RNAseq analysis of the drug jian-yan-ling (JYL) using both in vivo and in vitro models

Xiaobo Zhang, Yunliang Zhai, Dandan Zhang, Chang Che, Yayun Zhang, Quan Li, Xue Zhang, Lingrui Zhao

Heliyon. 2023 May; 9(5): e16143. Published online 2023 May 19. doi: 10.1016/j.heliyon.2023.e16143

PMCID:: PMC10213199

Abstract Article PDF–5.2M

Select item 96356444.

Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway

Rujuta Deshpande, Byoungchun Lee, Savraj S Grewal

G3 (Bethesda) 2022 Nov; 12(11): jkac163. Published online 2022 Jul 4. doi: 10.1093/g3journal/jkac163

PMCID:: PMC9635644

Abstract Article PDF–2.2M

Select item 81241855.

Combined Transcriptomic and Proteomic Analysis of Perk Toxicity Pathways

Rebeka Popovic, Ivana Celardo, Yizhou Yu, Ana C. Costa, Samantha H. Y. Loh, L. Miguel Martins

Int J Mol Sci. 2021 May; 22(9): 4598. Published online 2021 Apr 27. doi: 10.3390/ijms22094598

PMCID:: PMC8124185

Abstract Article PDF–6.1M

Select item 80002786.

Crtc modulates fasting programs associated with 1-C metabolism and inhibition of insulin signaling

Tian Wang, Ezra Wiater, Xinmin Zhang, John B. Thomas, Marc Montminy

Proc Natl Acad Sci U S A. 2021 Mar 23; 118(12): e2024865118. Published online 2021 Mar 15. doi: 10.1073/pnas.2024865118

PMCID:: PMC8000278

Abstract Article PDF–1.7M

Select item 69615787.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 61421958.

Serine metabolism in the brain regulates starvation-induced sleep suppression in Drosophila melanogaster

Jun Young Sonn, Jongbin Lee, Min Kyung Sung, Hwajung Ri, Jung Kyoon Choi, Chunghun Lim, Joonho Choe

Proc Natl Acad Sci U S A. 2018 Jul 3; 115(27): 7129–7134. Published online 2018 Jun 18. doi: 10.1073/pnas.1719033115

PMCID:: PMC6142195

Abstract Article PDF–1.3M

Select item 57653569.

RNA-Sequencing of Drosophila melanogaster Head Tissue on High-Sugar and High-Fat Diets

Wayne Hemphill, Osvaldo Rivera, Matthew Talbert

G3 (Bethesda) 2018 Jan; 8(1): 279–290. Published online 2017 Nov 15. doi: 10.1534/g3.117.300397

PMCID:: PMC5765356

Abstract Article PDF–2.4M

Select item 570780510.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900211.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 492804712.

Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome

Heath A. MacMillan, Jose M. Knee, Alice B. Dennis, Hiroko Udaka, Katie E. Marshall, Thomas J. S. Merritt, Brent J. Sinclair

Sci Rep. 2016; 6: 28999. Published online 2016 Jun 30. doi: 10.1038/srep28999

PMCID:: PMC4928047

Abstract Article PDF–3.1M

Select item 478811613.

Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, Halyna R. Shcherbata

Genetics. 2016 Mar; 202(3): 1167–1183. Published online 2016 Jan 22. doi: 10.1534/genetics.115.185371

PMCID:: PMC4788116

Abstract Article PDF–4.7M

Select item 473800514.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 469615215.

siRNA screen identifies QPCT as a druggable target for Huntington’s disease

Maria Jimenez-Sanchez, Wun Lam, Michael Hannus, Birte Sönnichsen, Sara Imarisio, Angeleen Fleming, Alessia Tarditi, Fiona Menzies, Teresa Ed Dami, Catherine Xu, Eduardo Gonzalez-Couto, Giulia Lazzeroni, Freddy Heitz, Daniela Diamanti, Luisa Massai, Venkata P. Satagopam, Guido Marconi, Chiara Caramelli, Arianna Nencini, Matteo Andreini, Gian Luca Sardone, Nicola P. Caradonna, Valentina Porcari, Carla Scali, Reinhard Schneider, Giuseppe Pollio, Cahir J. O’Kane, Andrea Caricasole, David C. Rubinsztein

Nat Chem Biol. Author manuscript; available in PMC 2015 Dec 30.

Published in final edited form as: Nat Chem Biol. 2015 May; 11(5): 347–354. Published online 2015 Apr 6. doi: 10.1038/nchembio.1790

PMCID:: PMC4696152

Abstract Article PDF–2.4M

Select item 452833016.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832917.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435288718.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 419909719.

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease

Roberta Tufi, Sonia Gandhi, Inês P. de Castro, Susann Lehmann, Plamena R. Angelova, David Dinsdale, Emma Deas, Hélène Plun-Favreau, Pierluigi Nicotera, Andrey Y. Abramov, Anne E. Willis, Giovanna R. Mallucci, Samantha H. Y. Loh, L. Miguel Martins

Nat Cell Biol. Author manuscript; available in PMC 2014 Oct 16.

Published in final edited form as: Nat Cell Biol. 2014 Feb; 16(2): 157–166. Published online 2014 Jan 19. doi: 10.1038/ncb2901

PMCID:: PMC4199097

Abstract Article PDF–2.3M

Select item 403647120.

Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease

Suvi Vartiainen, Shanjun Chen, Jack George, Tea Tuomela, Kaisa R. Luoto, Kevin M. C. O’Dell, Howard T. Jacobs

Dis Model Mech. 2014 Jun; 7(6): 635–648. Published online 2014 May 8. doi: 10.1242/dmm.016527

PMCID:: PMC4036471

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