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Items: 1 to 20 of 30

1.
SMYD3: a new regulator of adipocyte precursor proliferation at the early steps of differentiation
Tatjana Sajic, Chayenne Karine Ferreira Gomes, Marie Gasser, Tiziana Caputo, Nasim Bararpour, Esther Landaluce-Iturriria, Marc Augsburger, Nadia Walter, Alexandre Hainard, Isabel C. Lopez-Mejia, Tony Fracasso, Aurélien Thomas, Federica Gilardi
Int J Obes (Lond) 2024; 48(4): 557–566. Published online 2023 Dec 26. doi: 10.1038/s41366-023-01450-x
PMCID:
PMC10978492
AbstractArticlePDF–2.7M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model
Jamal B. Williams, Qing Cao, Wei Wang, Young-Ho Lee, Luye Qin, Ping Zhong, Yong Ren, Kaijie Ma, Zhen Yan
Nat Commun. 2023; 14: 91. Published online 2023 Jan 6. doi: 10.1038/s41467-022-35749-6
PMCID:
PMC9822922
AbstractArticlePDF–4.1M
4.
Methyltransferase SMYD3 impairs hypoxia tolerance by augmenting hypoxia signaling independent of its enzymatic activity
Zixuan Wang, Xiaoyun Chen, Sijia Fan, Chunchun Zhu, Hongyan Deng, Jinhua Tang, Xueyi Sun, Shuke Jia, Qian Liao, Wuhan Xiao, Xing Liu
J Biol Chem. 2022 Dec; 298(12): 102633. Published online 2022 Oct 21. doi: 10.1016/j.jbc.2022.102633
PMCID:
PMC9692045
AbstractArticlePDF–6.4M
5.
SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205
PMCID:
PMC9437563
AbstractArticlePDF–9.5M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development
Raffaella Fittipaldi, Pamela Floris, Valentina Proserpio, Franco Cotelli, Monica Beltrame, Giuseppina Caretti
Cells. 2021 May; 10(5): 1233. Published online 2021 May 18. doi: 10.3390/cells10051233
PMCID:
PMC8157265
AbstractArticlePDF–2.9M
8.
Cell geometry and the cytoskeleton impact the nucleo-cytoplasmic localisation of the SMYD3 methyltransferase
David Pereira, Alain Richert, Souhila Medjkane, Sylvie Hénon, Jonathan B. Weitzman
Sci Rep. 2020; 10: 20598. Published online 2020 Nov 26. doi: 10.1038/s41598-020-75833-9
PMCID:
PMC7691988
AbstractArticlePDF–2.8M
9.
Histone methyltransferase Smyd3 is a new regulator for vascular senescence
Di Yang, Gang Wei, Fen Long, Hongbo Nie, Xiaoli Tian, Lefeng Qu, ShuangXi Wang, Peng Li, Yue Qiu, Yang Wang, Wanjin Hong, Ting Ni, Xinhua Liu, Yi Zhun Zhu
Aging Cell. 2020 Sep; 19(9): e13212. Published online 2020 Aug 11. doi: 10.1111/acel.13212
PMCID:
PMC7511874
AbstractArticlePDF–2.1M
10.
The SMYD3 methyltransferase promotes myogenesis by activating the myogenin regulatory network
Roberta Codato, Martine Perichon, Arnaud Divol, Ella Fung, Athanassia Sotiropoulos, Anne Bigot, Jonathan B. Weitzman, Souhila Medjkane
Sci Rep. 2019; 9: 17298. Published online 2019 Nov 21. doi: 10.1038/s41598-019-53577-5
PMCID:
PMC6872730
AbstractArticlePDF–2.6M
11.
Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate
Rui Gao, Xingqun Liang, Sirisha Cheedipudi, Julio Cordero, Xue Jiang, Qingquan Zhang, Luca Caputo, Stefan Günther, Carsten Kuenne, Yonggang Ren, Shoumo Bhattacharya, Xuejun Yuan, Guillermo Barreto, Yihan Chen, Thomas Braun, Sylvia M. Evans, Yunfu Sun, Gergana Dobreva
Cell Res. 2019 Jun; 29(6): 486–501. Published online 2019 Apr 25. doi: 10.1038/s41422-019-0168-1
PMCID:
PMC6796926
AbstractArticlePDF–6.5M
12.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
13.
Smyd2 is a Myc-regulated gene critical for MLL-AF9 induced leukemogenesis
Sevgi Bagislar, Arianna Sabò, Theresia R. Kress, Mirko Doni, Paola Nicoli, Stefano Campaner, Bruno Amati
Oncotarget. 2016 Oct 11; 7(41): 66398–66415. Published online 2016 Sep 13. doi: 10.18632/oncotarget.12012
PMCID:
PMC5341809
AbstractArticlePDF–4.3M
14.
A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth
Alessia Peserico, Aldo Germani, Paola Sanese, Armenio Jorge Barbosa, Valeria Di Virgilio, Raffaella Fittipaldi, Edoardo Fabini, Carlo Bertucci, Greta Varchi, Mary Pat Moyer, Giuseppina Caretti, Alberto Del Rio, Cristiano Simone
J Cell Physiol. Author manuscript; available in PMC 2016 Aug 17.
Published in final edited form as: J Cell Physiol. 2015 Oct; 230(10): 2447–2460. doi: 10.1002/jcp.24975
PMCID:
PMC4988495
AbstractArticlePDF–2.9M
15.
Epigenetic control of Foxp3 by SMYD3 H3K4 histone methyltransferase controls iTreg development and regulates pathogenic T cell responses during pulmonary viral infection
Denise E. de Almeida Nagata, Hung-An Ting, Karen A. Cavassani, Matthew A. Schaller, Sumanta Mukherjee, Catherine Ptaschinski, Steven L. Kunkel, Nicholas W. Lukacs
Mucosal Immunol. Author manuscript; available in PMC 2016 Mar 1.
Published in final edited form as: Mucosal Immunol. 2015 Sep; 8(5): 1131–1143. Published online 2015 Feb 11. doi: 10.1038/mi.2015.4
PMCID:
PMC4532649
AbstractArticlePDF–1.8M
16.
Role of the ANKMY2-FKBP38 Axis in Regulation of the Sonic Hedgehog (Shh) Signaling Pathway
Shotaro Saita, Michiko Shirane, Tohru Ishitani, Nobuyuki Shimizu, Keiichi I. Nakayama
J Biol Chem. 2014 Sep 12; 289(37): 25639–25654. Published online 2014 Jul 30. doi: 10.1074/jbc.M114.558635
PMCID:
PMC4162168
AbstractArticlePDF–5.4M
17.
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
Pawel K. Mazur, Nicolas Reynoird, Purvesh Khatri, Pascal W.T.C. Jansen, Alex Wilkinson, Shichong Liu, Olena Barbash, Glenn S. Van Aller, Michael Huddleston, Dashyant Dhanak, Peter J. Tummino, Ryan G. Kruger, Benjamin Garcia, Atul J. Butte, Michiel Vermeulen, Julien Sage, Or Gozani
Nature. Author manuscript; available in PMC 2014 Dec 12.
Published in final edited form as: Nature. 2014 Jun 12; 510(7504): 283–287. Published online 2014 May 21. doi: 10.1038/nature13320
PMCID:
PMC4122675
AbstractArticlePDF–1.4M
18.
Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen
Hibret A. Adissu, Jeanne Estabel, David Sunter, Elizabeth Tuck, Yvette Hooks, Damian M. Carragher, Kay Clarke, Natasha A. Karp, Sanger Mouse Genetics Project, Susan Newbigging, Nora Jones, Lily Morikawa, Jacqueline K. White, Colin McKerlie
Dis Model Mech. 2014 May; 7(5): 515–524. Published online 2014 Mar 20. doi: 10.1242/dmm.015263
PMCID:
PMC4007403
AbstractArticle
19.
The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy
Valentina Proserpio, Raffaella Fittipaldi, James G. Ryall, Vittorio Sartorelli, Giuseppina Caretti
Genes Dev. 2013 Jun 1; 27(11): 1299–1312. doi: 10.1101/gad.217240.113
PMCID:
PMC3690402
AbstractArticlePDF–2.4M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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