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Items: 1 to 20 of 38

1.
Reduction of spermine synthase enhances autophagy to suppress Tau accumulation
Xianzun Tao, Jiaqi Liu, Zoraida Diaz-Perez, Jackson R. Foley, Ashley Nwafor, Tracy Murray Stewart, Robert A. Casero, Jr., R. Grace Zhai
Cell Death Dis. 2024 May; 15(5): 333. Published online 2024 May 13. doi: 10.1038/s41419-024-06720-8
PMCID:
PMC11091227
AbstractArticlePDF–3.9M
2.
Chromosomal Instability Causes Sensitivity to Polyamines and One-Carbon Metabolism
Anowarul Islam, Zeeshan Shaukat, David L. Newman, Rashid Hussain, Michael G. Ricos, Leanne Dibbens, Stephen L. Gregory
Metabolites. 2023 May; 13(5): 642. Published online 2023 May 9. doi: 10.3390/metabo13050642
PMCID:
PMC10221085
AbstractArticlePDF–3.2M
3.
Chronic sleep loss sensitizes Drosophila melanogaster to nitrogen stress
Joseph L. Bedont, Anna Kolesnik, Pavel Pivarshev, Dania Malik, Cynthia T. Hsu, Aalim Weljie, Amita Sehgal
Curr Biol. Author manuscript; available in PMC 2024 Apr 24.
Published in final edited form as: Curr Biol. 2023 Apr 24; 33(8): 1613–1623.e5. Published online 2023 Mar 24. doi: 10.1016/j.cub.2023.03.008
PMCID:
PMC10133188
AbstractArticlePDF–2.3M
4.
Next-generation large-scale binary protein interaction network for Drosophila melanogaster
Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr
Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0
PMCID:
PMC10105736
AbstractArticlePDF–3.2M
5.
Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells
Xianzun Tao, Yi Zhu, Zoraida Diaz-Perez, Seok-Ho Yu, Jackson R. Foley, Tracy Murray Stewart, Robert A. Casero, Jr., Richard Steet, R. Grace Zhai
JCI Insight. 2022 Jul 8; 7(13): e158457. Published online 2022 Jul 8. doi: 10.1172/jci.insight.158457
PMCID:
PMC9310527
AbstractArticlePDF–2.2M
6.
Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome
Mukund P. Tantak, Vandana Sekhar, Xianzun Tao, R. Grace Zhai, Otto Phanstiel, IV
J Med Chem. Author manuscript; available in PMC 2022 May 18.
Published in final edited form as: J Med Chem. 2021 Nov 11; 64(21): 15593–15607. Published online 2021 Oct 25. doi: 10.1021/acs.jmedchem.1c00419
PMCID:
PMC9115777
AbstractArticlePDF–2.1M
7.
Inter-Species Rescue of Mutant Phenotype—The Standard for Genetic Analysis of Human Genetic Disorders in Drosophila melanogaster Model
Alexandru Al. Ecovoiu, Attila Cristian Ratiu, Miruna Mihaela Micheu, Mariana Carmen Chifiriuc
Int J Mol Sci. 2022 Mar; 23(5): 2613. Published online 2022 Feb 27. doi: 10.3390/ijms23052613
PMCID:
PMC8909942
AbstractArticlePDF–1.3M
8.
Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes
Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis
G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349
PMCID:
PMC8664486
AbstractArticlePDF–3.1M
9.
The Role of Spermidine Synthase (SpdS) and Spermine Synthase (Sms) in Regulating Triglyceride Storage in Drosophila
Tahj S. Morales, Erik C. Avis, Elise K. Paskowski, Hamza Shabar, Shannon L. Nowotarski, Justin R. DiAngelo
Med Sci (Basel) 2021 Jun; 9(2): 27. Published online 2021 May 2. doi: 10.3390/medsci9020027
PMCID:
PMC8162547
AbstractArticlePDF–1.0M
10.
CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans
Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang
Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119
PMCID:
PMC6961578
AbstractArticlePDF–3.6M
11.
Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species
Piero Sanfilippo, Jiayu Wen, Eric C. Lai
Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0
PMCID:
PMC5707805
AbstractArticlePDF–3.2M
12.
Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster
Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira
RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117
PMCID:
PMC5689002
AbstractArticlePDF–4.0M
13.
Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome
Chong Li, Jennifer M. Brazill, Sha Liu, Christofer Bello, Yi Zhu, Marie Morimoto, Lauren Cascio, Rini Pauly, Zoraida Diaz-Perez, May Christine V. Malicdan, Hongbo Wang, Luigi Boccuto, Charles E. Schwartz, William A. Gahl, Cornelius F. Boerkoel, R. Grace Zhai
Nat Commun. 2017; 8: 1257. Published online 2017 Nov 2. doi: 10.1038/s41467-017-01289-7
Correction in:
Nat Commun. 2018; 9: 337.
PMCID:
PMC5668419
AbstractArticlePDF–8.2M
14.
Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome
Heath A. MacMillan, Jose M. Knee, Alice B. Dennis, Hiroko Udaka, Katie E. Marshall, Thomas J. S. Merritt, Brent J. Sinclair
Sci Rep. 2016; 6: 28999. Published online 2016 Jun 30. doi: 10.1038/srep28999
PMCID:
PMC4928047
AbstractArticlePDF–3.1M
15.
Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila
Andrey A. Parkhitko, Richard Binari, Nannan Zhang, John M. Asara, Fabio Demontis, Norbert Perrimon
Genes Dev. 2016 Jun 15; 30(12): 1409–1422. doi: 10.1101/gad.282277.116
PMCID:
PMC4926864
AbstractArticlePDF–1.4M
16.
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes
Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062
PMCID:
PMC4738005
AbstractArticlePDF–205K
17.
Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions
Albert J. Erives
Dev Genes Evol. 2015; 225(5): 259–273. Published online 2015 Jul 15. doi: 10.1007/s00427-015-0508-1
PMCID:
PMC4568025
AbstractArticlePDF–2.8M
18.
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders
Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium
G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937
PMCID:
PMC4528330
AbstractArticlePDF–2.2M
19.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data
Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium
G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929
PMCID:
PMC4528329
AbstractArticlePDF–4.9M
20.
The Release 6 reference sequence of the Drosophila melanogaster genome
Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker
Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114
PMCID:
PMC4352887
AbstractArticlePDF–1022K

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