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Items: 1 to 20 of 36

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
p62 and NBR1 functions are dispensable for aggrephagy in mouse ESCs and ESC-derived neurons
Riccardo Trapannone, Julia Romanov, Sascha Martens
Life Sci Alliance. 2023 Nov; 6(11): e202301936. Published online 2023 Aug 24. doi: 10.26508/lsa.202301936
PMCID:
PMC10460970
AbstractArticlePDF–3.2M
3.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
4.
Non-autophagy Role of Atg5 and NBR1 in Unconventional Secretion of IL-12 Prevents Gut Dysbiosis and Inflammation
Seth D Merkley, Samuel M Goodfellow, Yan Guo, Zoe E R Wilton, Janie R Byrum, Kurt C Schwalm, Darrell L Dinwiddie, Rama R Gullapalli, Vojo Deretic, Anthony Jimenez Hernandez, Steven B Bradfute, Julie G In, Eliseo F Castillo
J Crohns Colitis. 2022 Feb; 16(2): 259–274. Published online 2021 Aug 10. doi: 10.1093/ecco-jcc/jjab144
PMCID:
PMC8864635
AbstractArticlePDF–3.5M
5.
NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
Jianfeng Huang, Juan F. Linares, Angeles Duran, Wenmin Xia, Alan R. Saltiel, Timo D. Müller, Maria T. Diaz-Meco, Jorge Moscat
Nat Commun. 2021; 12: 2876. Published online 2021 May 17. doi: 10.1038/s41467-021-23085-0
PMCID:
PMC8129077
AbstractArticlePDF–2.3M
6.
Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease
Sandra Franco-Iborra, Ainhoa Plaza-Zabala, Marta Montpeyo, David Sebastian, Miquel Vila, Marta Martinez-Vicente
Autophagy. 2021; 17(3): 672–689. Published online 2020 Feb 24. doi: 10.1080/15548627.2020.1728096
PMCID:
PMC8032238
AbstractArticlePDF–6.1M
7.
Annexin-A1 SUMOylation regulates microglial polarization after cerebral ischemia by modulating IKKα stability via selective autophagy
Xing Li, Qian Xia, Meng Mao, Huijuan Zhou, Lu Zheng, Yi Wang, Zhen Zeng, Lulu Yan, Yin Zhao, Jing Shi
Sci Adv. 2021 Jan; 7(4): eabc5539. Published online 2021 Jan 20. doi: 10.1126/sciadv.abc5539
PMCID:
PMC7817101
AbstractArticlePDF–2.8M
8.
Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth During Mammary Tumor Progression
Timothy Marsh, Candia M. Kenific, Deepthisri Suresh, Hugo Gonzalez, Eliah R. Shamir, Wenbin Mei, Alexandra Tankka, Andrew M. Leidal, Sandhya Kalavacherla, Kimberly Woo, Zena Werb, Jayanta Debnath
Dev Cell. Author manuscript; available in PMC 2021 Mar 9.
Published in final edited form as: Dev Cell. 2020 Mar 9; 52(5): 591–604.e6. Published online 2020 Feb 20. doi: 10.1016/j.devcel.2020.01.025
PMCID:
PMC7108946
AbstractArticlePDF–3.0M
9.
Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis
Junji Yamaguchi, Chigure Suzuki, Tomohisa Nanao, Soichirou Kakuta, Kentarou Ozawa, Isei Tanida, Tatsuya Saitoh, Takehiko Sunabori, Masaaki Komatsu, Keiji Tanaka, Shigeki Aoki, Kenji Sakimura, Yasuo Uchiyama
Autophagy. 2018; 14(5): 764–777. Published online 2018 Mar 6. doi: 10.1080/15548627.2017.1314897
PMCID:
PMC6070006
AbstractArticlePDF–2.5M
10.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
11.
NBR1 enables autophagy-dependent focal adhesion turnover
Candia M. Kenific, Samantha J. Stehbens, Juliet Goldsmith, Andrew M. Leidal, Nathalie Faure, Jordan Ye, Torsten Wittmann, Jayanta Debnath
J Cell Biol. 2016 Feb 29; 212(5): 577–590. doi: 10.1083/jcb.201503075
PMCID:
PMC4772495
AbstractArticlePDF–2.4M
12.
Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging
Victoria Hung, Peng Zou, Hyun-Woo Rhee, Namrata D. Udeshi, Valentin Cracan, Tanya Svinkina, Steven A. Carr, Vamsi K. Mootha, Alice Y. Ting
Mol Cell. Author manuscript; available in PMC 2016 Feb 5.
Published in final edited form as: Mol Cell. 2014 Jul 17; 55(2): 332–341. Published online 2014 Jul 4. doi: 10.1016/j.molcel.2014.06.003
PMCID:
PMC4743503
AbstractArticlePDF–770K
13.
p62 is required to retain short-term repopulating and myeloid progenitor cells through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche
Kyung Hee Chang, Amitava Sengupta, Ramesh C. Nayak, Angeles Duran, Sang Jun Lee, Ronald G. Pratt, Ashley M. Wellendorf, Sarah E. Hill, Marcus Watkins, Daniel Gonzalez-Nieto, Bruce J. Aronow, Daniel T. Starczynowski, Roberto Civitelli, Maria T. Diaz-Meco, Jorge Moscat, Jose A. Cancelas
Cell Rep. Author manuscript; available in PMC 2015 Dec 24.
Published in final edited form as: Cell Rep. 2014 Dec 24; 9(6): 2084–2097. Published online 2014 Dec 18. doi: 10.1016/j.celrep.2014.11.031
PMCID:
PMC4277497
AbstractArticlePDF–1.5M
14.
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity
Tse-Chun Kuo, Chun-Ting Chen, Desiree Baron, Tamer T. Onder, Sabine Loewer, Sandra Almeida, Cara Weismann, Ping Xu, Jean-Marie Houghton, Fen-Biao Gao, George Q. Daley, Stephen Doxsey
Nat Cell Biol. Author manuscript; available in PMC 2014 Oct 24.
Published in final edited form as: Nat Cell Biol. 2011 Oct; 13(10): 1214–1223. Published online 2011 Sep 11. doi: 10.1038/ncb2332
Correction in:
volume 13 on page 1467
PMCID:
PMC4208311
AbstractArticlePDF–1.3M
15.
A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose-tissue inflammation in obesity
Eloy D. Hernandez, Sang Jun Lee, Ji Young Kim, Angeles Duran, Juan F. Linares, Tomoko Yajima, Timo D. Müller, Matthias H. Tschöp, Steven R. Smith, Maria T. Diaz-Meco, Jorge Moscat
Cell Metab. Author manuscript; available in PMC 2015 Sep 2.
Published in final edited form as: Cell Metab. 2014 Sep 2; 20(3): 499–511. Published online 2014 Jul 17. doi: 10.1016/j.cmet.2014.06.008
PMCID:
PMC4156534
AbstractArticlePDF–1.7M
16.
Phosphorylation of NBR1 by GSK3 modulates protein aggregation
Anne-Sophie Nicot, Francesca Lo Verso, Francesca Ratti, Fanny Pilot-Storck, Nathalie Streichenberger, Marco Sandri, Laurent Schaeffer, Evelyne Goillot
Autophagy. 2014 Jun 1; 10(6): 1036–1053. Published online 2014 Mar 31. doi: 10.4161/auto.28479
PMCID:
PMC4091167
AbstractArticlePDF–8.8M
17.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
MAP1B Interaction with the FW Domain of the Autophagic Receptor Nbr1 Facilitates Its Association to the Microtubule Network
Katie Marchbank, Sarah Waters, Roland G. Roberts, Ellen Solomon, Caroline A. Whitehouse
Int J Cell Biol. 2012; 2012: 208014. Published online 2012 May 10. doi: 10.1155/2012/208014
PMCID:
PMC3357945
AbstractArticlePDF–5.2M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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