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Items: 1 to 20 of 42

1.
Novel 5α‐steroid reductase (SRD5A3, type‐3) is overexpressed in hormone‐refractory prostate cancer
Motohide Uemura, Kenji Tamura, Suyoun Chung, Seijiro Honma, Akihiko Okuyama, Yusuke Nakamura, Hidewaki Nakagawa
Cancer Sci. 2008 Jan; 99(1): 81–86. Published online 2007 Nov 6. doi: 10.1111/j.1349-7006.2007.00656.x
PMCID:
PMC11158902
AbstractArticlePDF–214K
2.
Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing
Ben Bar-Sadeh, Or E. Amichai, Lilach Pnueli, Khurshida Begum, Gregory Leeman, Richard D. Emes, Reinhard Stöger, Gillian R. Bentley, Philippa Melamed
BMC Biol. 2022; 20: 11. Published online 2022 Jan 7. doi: 10.1186/s12915-021-01219-6
PMCID:
PMC8742331
AbstractArticlePDF–1.5M
3.
Treatment of Benign Prostatic Hyperplasia by Natural Drugs
Eszter Csikós, Adrienn Horváth, Kamilla Ács, Nóra Papp, Viktória Lilla Balázs, Marija Sollner Dolenc, Maša Kenda, Nina Kočevar Glavač, Milan Nagy, Michele Protti, Laura Mercolini, Györgyi Horváth, Ágnes Farkas, on behalf of the OEMONOM
Molecules. 2021 Dec; 26(23): 7141. Published online 2021 Nov 25. doi: 10.3390/molecules26237141
PMCID:
PMC8659259
AbstractArticlePDF–562K
4.
Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity
Marta Sumińska, Rafał Podgórski, Piotr Fichna, Marta Fichna
Front Endocrinol (Lausanne) 2021; 12: 759971. Published online 2021 Oct 26. doi: 10.3389/fendo.2021.759971
PMCID:
PMC8577858
AbstractArticlePDF–381K
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma
Renjie Dou, Jinjun Qian, Wei Wu, Yanxin Zhang, Yuxia Yuan, Mengjie Guo, Rongfang Wei, Shu Yang, Artur Jurczyszyn, Siegfried Janz, Meral Beksac, Chunyan Gu, Ye Yang
Cell Death Dis. 2021 Feb; 12(2): 206. Published online 2021 Feb 24. doi: 10.1038/s41419-021-03510-4
PMCID:
PMC7904855
AbstractArticlePDF–4.5M
7.
Expression in Escherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5α-Reductases
Hwei-Ming Peng, Juan Valentín-Goyco, Sang-Choul Im, Bing Han, Jiayan Liu, Jie Qiao, Richard J Auchus
Endocrinology. 2020 Aug; 161(8): bqaa117. Published online 2020 Jul 6. doi: 10.1210/endocr/bqaa117
PMCID:
PMC7383974
AbstractArticle
8.
Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development
Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong
J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107
PMCID:
PMC6763242
AbstractArticlePDF–12M
9.
Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice
Tracy C S Mak, Dawn E W Livingstone, Mark Nixon, Brian R Walker, Ruth Andrew
Endocrinology. 2019 Sep; 160(9): 2061–2073. Published online 2019 Jun 14. doi: 10.1210/en.2019-00236
PMCID:
PMC6735737
AbstractArticle
10.
Molecular Analysis of the SRD5A1 and SRD5A2 Genes in Patients with Benign Prostatic Hyperplasia with Regard to Metabolic Parameters and Selected Hormone Levels
Aleksandra Rył, Iwona Rotter, Anna Grzywacz, Iwona Małecka, Karolina Skonieczna-Żydecka, Katarzyna Grzesiak, Marcin Słojewski, Aleksandra Szylińska, Olimpia Sipak-Szmigiel, Małgorzata Piasecka, Kinga Walczakiewicz, Maria Laszczyńska
Int J Environ Res Public Health. 2017 Nov; 14(11): 1318. Published online 2017 Oct 30. doi: 10.3390/ijerph14111318
PMCID:
PMC5707957
AbstractArticlePDF–317K
11.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
12.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
13.
5α-reductase activity in women with polycystic ovary syndrome: a systematic review and meta-analysis
Chuyan Wu, Ke Wei, Zhongli Jiang
Reprod Biol Endocrinol. 2017; 15: 21. Published online 2017 Mar 27. doi: 10.1186/s12958-017-0242-9
PMCID:
PMC5369013
AbstractArticlePDF–1.4M
14.
Characterization of Prostate Cancer Bone Metastases According to Expression Levels of Steroidogenic Enzymes and Androgen Receptor Splice Variants
Emma Jernberg, Elin Thysell, Erik Bovinder Ylitalo, Stina Rudolfsson, Sead Crnalic, Anders Widmark, Anders Bergh, Pernilla Wikström
PLoS One. 2013; 8(11): e77407. Published online 2013 Nov 7. doi: 10.1371/journal.pone.0077407
PMCID:
PMC3820691
AbstractArticlePDF–1.1M
15.
Genome-Wide Association Study of d-Amphetamine Response in Healthy Volunteers Identifies Putative Associations, Including Cadherin 13 (CDH13)
Amy B. Hart, Barbara E. Engelhardt, Margaret C. Wardle, Greta Sokoloff, Matthew Stephens, Harriet de Wit, Abraham A. Palmer
PLoS One. 2012; 7(8): e42646. Published online 2012 Aug 28. doi: 10.1371/journal.pone.0042646
PMCID:
PMC3429486
AbstractArticlePDF–711K
16.
Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women
Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki
PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695
PMCID:
PMC3349734
AbstractArticlePDF–377K
17.
Androgen Regulation of 5α-Reductase Isoenzymes in Prostate Cancer: Implications for Prostate Cancer Prevention
Jin Li, Zhiyong Ding, Zhengxin Wang, Jing-Fang Lu, Sankar N. Maity, Nora M. Navone, Christopher J. Logothetis, Gordon B. Mills, Jeri Kim
PLoS One. 2011; 6(12): e28840. Published online 2011 Dec 14. doi: 10.1371/journal.pone.0028840
PMCID:
PMC3237548
AbstractArticlePDF–1.6M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
Kai-Hsiung Chang, Rui Li, Mahboubeh Papari-Zareei, Lori Watumull, Yan Daniel Zhao, Richard J. Auchus, Nima Sharifi
Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33): 13728–13733. Published online 2011 Jul 27. doi: 10.1073/pnas.1107898108
PMCID:
PMC3158152
AbstractArticlePDF–610K
20.
Variation in Genes Encoding the Neuroactive Steroid Synthetic Enzymes 5α-Reductase Type 1 and 3α-Reductase Type 2 is Associated with Alcohol Dependence
Verica Milivojevic, Henry R. Kranzler, Joel Gelernter, Linda Burian, Jonathan Covault
Alcohol Clin Exp Res. Author manuscript; available in PMC 2012 May 1.
Published in final edited form as: Alcohol Clin Exp Res. 2011 May; 35(5): 946–952. Published online 2011 Feb 15. doi: 10.1111/j.1530-0277.2010.01425.x
PMCID:
PMC3083475
AbstractArticlePDF–488K

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