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    Items: 1 to 20 of 134

    1.
    Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
    Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
    Cell. Author manuscript; available in PMC 2024 Oct 26.
    Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
    PMCID:
    PMC11209935
    AbstractArticlePDF–3.0M
    2.
    Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma
    Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn
    Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255
    PMCID:
    PMC10916866
    AbstractArticlePDF–4.7M
    3.
    Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly
    Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun
    Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0
    PMCID:
    PMC10799903
    AbstractArticlePDF–25M
    4.
    Integrins regulate hERG1 dynamics by girdin-dependent Gαi3: signaling and modeling in cancer cells
    Claudia Duranti, Jessica Iorio, Giacomo Bagni, Ginevra Chioccioli Altadonna, Thibault Fillion, Matteo Lulli, Franco Nicolas D’Alessandro, Alberto Montalbano, Elena Lastraioli, Duccio Fanelli, Stefano Coppola, Thomas Schmidt, Francesco Piazza, Andrea Becchetti, Annarosa Arcangeli
    Life Sci Alliance. 2024 Jan; 7(1): e202302135. Published online 2023 Nov 3. doi: 10.26508/lsa.202302135
    PMCID:
    PMC10624597
    AbstractArticlePDF–5.5M
    5.
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
    Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
    Science. Author manuscript; available in PMC 2023 Oct 31.
    Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
    PMCID:
    PMC10617673
    AbstractArticlePDF–3.6M
    6.
    C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains
    Julia Jülg, Dieter Edbauer, Christian Behrends
    EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895
    PMCID:
    PMC10398660
    AbstractArticlePDF–2.4M
    7.
    Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry
    Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang
    Anal Chem. Author manuscript; available in PMC 2023 Jun 21.
    Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986
    PMCID:
    PMC10284117
    AbstractArticlePDF–2.5M
    8.
    Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR
    Chengpeng Yu, Dean Rao, Tiantian Wang, Jiaqi Sheng, Enjun Lv, Long Zhang, Xun Lu, Jingjing Yu, Huifang Liang, Jia Song, Wenjie Huang
    J Cell Mol Med. 2023 Jun; 27(11): 1523–1538. Published online 2023 May 2. doi: 10.1111/jcmm.17757
    PMCID:
    PMC10243154
    AbstractArticlePDF–51M
    9.
    TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
    Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
    Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
    PMCID:
    PMC10237422
    AbstractArticlePDF–23M
    10.
    Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis
    Ya Li, Jin-long Chai, Xin Shi, Yu Feng, Jia-jun Li, Li-na Zhou, Cong Cao, Ke-ran Li
    Theranostics. 2023; 13(7): 2319–2336. Published online 2023 Apr 17. doi: 10.7150/thno.80749
    PMCID:
    PMC10157725
    AbstractArticlePDF–10M
    11.
    The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia
    Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy
    BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4
    PMCID:
    PMC10080908
    AbstractArticlePDF–3.2M
    12.
    METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis
    Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang
    EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762
    PMCID:
    PMC9986817
    AbstractArticlePDF–3.5M
    13.
    Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma
    Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li
    Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x
    PMCID:
    PMC9950447
    AbstractArticlePDF–8.4M
    14.
    TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
    Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel
    J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144
    PMCID:
    PMC9797988
    AbstractArticlePDF–6.9M
    15.
    HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
    Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
    Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
    PMCID:
    PMC9772558
    AbstractArticlePDF–8.2M
    16.
    Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia
    Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
    Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437
    PMCID:
    PMC9733937
    AbstractArticlePDF–2.2M
    17.
    ALS-linked loss of Cyclin-F function affects HSP90
    Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
    Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
    PMCID:
    PMC9481933
    AbstractArticlePDF–3.5M
    18.
    Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy
    Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui
    Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y
    PMCID:
    PMC9440653
    AbstractArticlePDF–2.9M
    19.
    ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
    Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
    Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
    PMCID:
    PMC9231623
    AbstractArticlePDF–6.0M
    20.
    LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression
    Xuexue Xu, Pengsheng Ding, Lan Shi, Gang Wu, Xiaoling Ma
    BMC Cancer. 2022; 22: 630. Published online 2022 Jun 8. doi: 10.1186/s12885-022-09680-4
    PMCID:
    PMC9175482
    AbstractArticlePDF–15M

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