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Items: 1 to 20 of 58

1.
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility
Meng-Fei Zhang, Shi-Cheng Wan, Wen-Bo Chen, Dong-Hui Yang, Wen-Qing Liu, Ba-Lun Li, Aili Aierken, Xiao-Min Du, Yun-Xiang Li, Wen-Ping Wu, Xin-Chun Yang, Yu-Dong Wei, Na Li, Sha Peng, Xue-Ling Li, Guang-Peng Li, Jin-Lian Hua
Zool Res. 2023 May 18; 44(3): 505–521. doi: 10.24272/j.issn.2095-8137.2022.440
PMCID:
PMC10236308
AbstractArticlePDF–7.8M
2.
Topologically associating domain boundaries are required for normal genome function
Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li, Ana Alcaina Caro, Yoko Fukuda-Yuzawa, Guy Kelman, Adyam Akeza, Matthew J. Blow, Quan Pham, Anne N. Harrington, Janeth Godoy, Eman M. Meky, Kianna von Maydell, Riana D. Hunter, Jennifer A. Akiyama, Catherine S. Novak, Ingrid Plajzer-Frick, Veena Afzal, Stella Tran, Javier Lopez-Rios, Michael E. Talkowski, K. C. Kent Lloyd, Bing Ren, Diane E. Dickel, Axel Visel, Len A. Pennacchio
Commun Biol. 2023; 6: 435. Published online 2023 Apr 20. doi: 10.1038/s42003-023-04819-w
PMCID:
PMC10119121
AbstractArticlePDF–3.2M
3.
Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions
Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco
Nat Commun. 2023; 14: 1439. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37199-0
PMCID:
PMC10017703
AbstractArticlePDF–16M
4.
SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse
Aya Uchida, Kenya Imaimatsu, Honoka Suzuki, Xiao Han, Hiroki Ushioda, Mami Uemura, Kasane Imura-Kishi, Ryuji Hiramatsu, Hinako M. Takase, Yoshikazu Hirate, Atsuo Ogura, Masami Kanai-Azuma, Akihiko Kudo, Yoshiakira Kanai
Nat Commun. 2022; 13: 7860. Published online 2022 Dec 21. doi: 10.1038/s41467-022-35465-1
PMCID:
PMC9772346
AbstractArticlePDF–15M
5.
Genomics of sexual cell fate transdifferentiation in the mouse gonad
Mark W Murphy, Micah D Gearhart, Andrew Wheeler, Vivian J Bardwell, David Zarkower
G3 (Bethesda) 2022 Dec; 12(12): jkac267. Published online 2022 Oct 6. doi: 10.1093/g3journal/jkac267
PMCID:
PMC9713387
AbstractArticlePDF–4.3M
6.
Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate
Nour Abou Nader, Amélie Ménard, Adrien Levasseur, Guillaume St-Jean, Derek Boerboom, Gustavo Zamberlam, Alexandre Boyer
Int J Mol Sci. 2022 Nov; 23(21): 13585. Published online 2022 Nov 5. doi: 10.3390/ijms232113585
PMCID:
PMC9655313
AbstractArticlePDF–4.1M
7.
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway
Moïra Rossitto, Stephanie Déjardin, Chris M. Rands, Stephanie Le Gras, Roberta Migale, Mahmoud-Reza Rafiee, Yasmine Neirijnck, Alain Pruvost, Anvi Laetitia Nguyen, Guillaume Bossis, Florence Cammas, Lionel Le Gallic, Dagmar Wilhelm, Robin Lovell-Badge, Brigitte Boizet-Bonhoure, Serge Nef, Francis Poulat
Nat Commun. 2022; 13: 4412. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32061-1
PMCID:
PMC9338040
AbstractArticlePDF–11M
8.
Somatic cell fate maintenance in mouse fetal testes via autocrine/paracrine action of AMH and activin B
Karina F. Rodriguez, Paula R. Brown, Ciro M. Amato, Barbara Nicol, Chia-Feng Liu, Xin Xu, Humphrey Hung-Chang Yao
Nat Commun. 2022; 13: 4130. Published online 2022 Jul 15. doi: 10.1038/s41467-022-31486-y
PMCID:
PMC9287316
AbstractArticlePDF–4.1M
9.
DMRT1: an ancient sexual regulator required for human gonadogenesis
David Zarkower, Mark W. Murphy
Sex Dev. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Sex Dev. 2022; 16(2-3): 112–125. Published online 2021 Sep 1. doi: 10.1159/000518272
PMCID:
PMC8885888
AbstractArticlePDF–787K
10.
DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency
Jumpei Taguchi, Hirofumi Shibata, Mio Kabata, Masaki Kato, Kei Fukuda, Akito Tanaka, Sho Ohta, Tomoyo Ukai, Kanae Mitsunaga, Yosuke Yamada, So I Nagaoka, Sho Yamazawa, Kotaro Ohnishi, Knut Woltjen, Tetsuo Ushiku, Manabu Ozawa, Mitinori Saitou, Yoichi Shinkai, Takuya Yamamoto, Yasuhiro Yamada
Nat Commun. 2021; 12: 5041. Published online 2021 Aug 19. doi: 10.1038/s41467-021-25249-4
PMCID:
PMC8377058
AbstractArticlePDF–5.7M
11.
Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2
Koichiro Ono, Kenji Hata, Eriko Nakamura, Shota Ishihara, Sachi Kobayashi, Masako Nakanishi, Michiko Yoshida, Yoshifumi Takahata, Tomohiko Murakami, Seiichi Takenoshita, Toshihisa Komori, Riko Nishimura, Toshiyuki Yoneda
Commun Biol. 2021; 4: 326. Published online 2021 Mar 11. doi: 10.1038/s42003-021-01848-1
PMCID:
PMC7952723
AbstractArticlePDF–2.3M
12.
Testis formation in XX individuals resulting from novel pathogenic variants in Wilms’ tumor 1 (WT1) gene
Caroline Eozenou, Nitzan Gonen, Maria Sol Touzon, Anne Jorgensen, Svetlana A. Yatsenko, Leila Fusee, Alaa K. Kamel, Balazs Gellen, Gabriela Guercio, Priti Singh, Selma Witchel, Andrea J. Berman, Rana Mainpal, Mehdi Totonchi, Anahita Mohseni Meybodi, Masomeh Askari, Tiphanie Merel-Chali, Joelle Bignon-Topalovic, Roberta Migale, Mariana Costanzo, Roxana Marino, Pablo Ramirez, Natalia Perez Garrido, Esperanza Berensztein, Mona K. Mekkawy, John C. Schimenti, Rita Bertalan, Inas Mazen, Ken McElreavey, Alicia Belgorosky, Robin Lovell-Badge, Aleksandar Rajkovic, Anu Bashamboo
Proc Natl Acad Sci U S A. 2020 Jun 16; 117(24): 13680–13688. Published online 2020 Jun 3. doi: 10.1073/pnas.1921676117
PMCID:
PMC7306989
AbstractArticlePDF–2.1M
13.
Mouse Gonad Development in the Absence of the Pro-Ovary Factor WNT4 and the Pro-Testis Factor SOX9
Furong Tang, Nainoa Richardson, Audrey Albina, Marie-Christine Chaboissier, Aitana Perea-Gomez
Cells. 2020 May; 9(5): 1103. Published online 2020 Apr 29. doi: 10.3390/cells9051103
PMCID:
PMC7291083
AbstractArticlePDF–15M
14.
Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals
Nainoa Richardson, Isabelle Gillot, Elodie P Gregoire, Sameh A Youssef, Dirk de Rooij, Alain de Bruin, Marie-Cécile De Cian, Marie-Christine Chaboissier
eLife. 2020; 9: e53972. Published online 2020 May 26. doi: 10.7554/eLife.53972
PMCID:
PMC7250573
AbstractArticlePDF–11M
15.
RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2
Barbara Nicol, Sara A. Grimm, Frédéric Chalmel, Estelle Lecluze, Maëlle Pannetier, Eric Pailhoux, Elodie Dupin-De-Beyssat, Yann Guiguen, Blanche Capel, Humphrey H.-C. Yao
Nat Commun. 2019; 10: 5116. Published online 2019 Nov 11. doi: 10.1038/s41467-019-13060-1
PMCID:
PMC6848188
AbstractArticlePDF–13M
16.
Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells
Tadashi Nakagawa, Teng Zhang, Ryo Kushi, Seiji Nakano, Takahiro Endo, Makiko Nakagawa, Noriko Yanagihara, David Zarkower, Keiko Nakayama
Development. 2017 Nov 15; 144(22): 4137–4147. doi: 10.1242/dev.158485
PMCID:
PMC5719248
AbstractArticle
17.
Sex determination and maintenance: the role of DMRT1 and FOXL2
Shengsong Huang, Leping Ye, Haolin Chen
Asian J Androl. 2017 Nov-Dec; 19(6): 619–624. Published online 2017 Jan 13. doi: 10.4103/1008-682X.194420
PMCID:
PMC5676419
AbstractArticlePDF–223K
18.
β-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression
Yaqiong Li, Lianjun Zhang, Yuqiong Hu, Min Chen, Feng Han, Yan Qin, Min Chen, Xiuhong Cui, Shuguang Duo, Fuchou Tang, Fei Gao
J Biol Chem. 2017 Oct 27; 292(43): 17577–17586. Published online 2017 Sep 12. doi: 10.1074/jbc.M117.811349
PMCID:
PMC5663863
AbstractArticlePDF–2.6M
19.
In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures
Massilva Rahmoun, Rowena Lavery, Sabine Laurent-Chaballier, Nicolas Bellora, Gayle K. Philip, Moïra Rossitto, Aleisha Symon, Eric Pailhoux, Florence Cammas, Jessica Chung, Stefan Bagheri-Fam, Mark Murphy, Vivian Bardwell, David Zarkower, Brigitte Boizet-Bonhoure, Philippe Clair, Vincent R. Harley, Francis Poulat
Nucleic Acids Res. 2017 Jul 7; 45(12): 7191–7211. Published online 2017 May 2. doi: 10.1093/nar/gkx328
PMCID:
PMC5499551
AbstractArticlePDF–10M
20.
DMRT1 Is Required for Mouse Spermatogonial Stem Cell Maintenance and Replenishment
Teng Zhang, Jon Oatley, Vivian J. Bardwell, David Zarkower
PLoS Genet. 2016 Sep; 12(9): e1006293. Published online 2016 Sep 1. doi: 10.1371/journal.pgen.1006293
PMCID:
PMC5008761
AbstractArticlePDF–15M

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