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Items: 1 to 20 of 29

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
4.
Agonist-independent Gαz activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes
Michael D. Schaid, Cara L. Green, Darby C. Peter, Shannon J. Gallagher, Erin Guthery, Kathryn A. Carbajal, Jeffrey M. Harrington, Grant M. Kelly, Austin Reuter, Molly L. Wehner, Allison L. Brill, Joshua C. Neuman, Dudley W. Lamming, Michelle E. Kimple
J Biol Chem. 2021 Jan-Jun; 296: 100056. Published online 2020 Nov 24. doi: 10.1074/jbc.RA120.015585
PMCID:
PMC7948463
AbstractArticlePDF–3.3M
5.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
6.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
7.
RNA binding proteins co-localize with small tau inclusions in tauopathy
Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin
Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5
PMCID:
PMC6069705
AbstractArticlePDF–5.5M
8.
Gnaz couples the circadian and dopaminergic system to G protein-mediated signaling in mouse photoreceptors
Patrick Vancura, Shaima Abdelhadi, Erika Csicsely, Kenkichi Baba, Gianluca Tosini, P. Michael Iuvone, Rainer Spessert
PLoS One. 2017; 12(10): e0187411. Published online 2017 Oct 31. doi: 10.1371/journal.pone.0187411
PMCID:
PMC5663513
AbstractArticlePDF–7.3M
9.
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling
Brent Wilkinson, Jing Li, Marcelo P. Coba
Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3
PMCID:
PMC5509740
AbstractArticlePDF–4.6M
10.
Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction
Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum, II
Neural Plast. 2017; 2017: 4153076. Published online 2017 May 28. doi: 10.1155/2017/4153076
PMCID:
PMC5467389
AbstractArticlePDF–3.2M
11.
The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice
Rachel J. Fenske, Mark T. Cadena, Quincy E. Harenda, Haley N. Wienkes, Kathryn Carbajal, Michael D. Schaid, Erin Laundre, Allison L. Brill, Nathan A. Truchan, Harpreet Brar, Jaclyn Wisinski, Jinjin Cai, Timothy E. Graham, Feyza Engin, Michelle E. Kimple
Endocrinology. 2017 Jun 1; 158(6): 1645–1658. Published online 2017 Apr 14. doi: 10.1210/en.2016-1700
PMCID:
PMC5460933
AbstractArticle
12.
Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity
Tara Vanderweyde, Daniel J. Apicco, Katherine Youmans-Kidder, Peter E.A. Ash, Casey Cook, Edroaldo Lummertz da Rocha, Karen Jansen-West, Alissa A. Frame, Allison Citro, John D. Leszyk, Pavel Ivanov, Jose F. Abisambra, Martin Steffen, Hu Li, Leonard Petrucelli, Benjamin Wolozin
Cell Rep. Author manuscript; available in PMC 2017 Feb 24.
Published in final edited form as: Cell Rep. 2016 May 17; 15(7): 1455–1466. Published online 2016 May 6. doi: 10.1016/j.celrep.2016.04.045
PMCID:
PMC5325702
AbstractArticlePDF–2.1M
13.
Gas1 is a receptor for sonic hedgehog to repel enteric axons
Shiying Jin, David C. Martinelli, Xiaobin Zheng, Marc Tessier-Lavigne, Chen-Ming Fan
Proc Natl Acad Sci U S A. 2015 Jan 6; 112(1): E73–E80. Published online 2014 Dec 22. doi: 10.1073/pnas.1418629112
PMCID:
PMC4291612
AbstractArticlePDF–1.5M
14.
Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification
Jean B. Regard, Deepti Malhotra, Jelena Gvozdenovic-Jeremic, Michelle Josey, Min Chen, Lee S. Weinstein, Jianming Lu, Eileen M. Shore, Frederick S. Kaplan, Yingzi Yang
Nat Med. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Nat Med. 2013 Nov; 19(11): 1505–1512. Published online 2013 Sep 29. doi: 10.1038/nm.3314
PMCID:
PMC3917515
AbstractArticlePDF–1.6M
15.
Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
Dyna I. Shirasaki, Erin R. Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H. Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A. Loo, X. William Yang
Neuron. Author manuscript; available in PMC 2013 Jul 12.
Published in final edited form as: Neuron. 2012 Jul 12; 75(1): 41–57. doi: 10.1016/j.neuron.2012.05.024
PMCID:
PMC3432264
AbstractArticlePDF–4.9M
16.
Deletion of GαZ Protein Protects against Diet-induced Glucose Intolerance via Expansion of β-Cell Mass
Michelle E. Kimple, Jennifer B. Moss, Harpreet K. Brar, Taylor C. Rosa, Nathan A. Truchan, Renee L. Pasker, Christopher B. Newgard, Patrick J. Casey
J Biol Chem. 2012 Jun 8; 287(24): 20344–20355. Published online 2012 Mar 28. doi: 10.1074/jbc.M112.359745
PMCID:
PMC3370216
AbstractArticlePDF–3.9M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Augmented glucose-induced insulin release in mice lacking Go2, but not Go1 or Gi proteins
Ying Wang, Sangeun Park, Neil S. Bajpayee, Yoshiko Nagaoka, Guylain Boulay, Lutz Birnbaumer, Meisheng Jiang
Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4): 1693–1698. Published online 2011 Jan 10. doi: 10.1073/pnas.1018903108
PMCID:
PMC3029743
AbstractArticlePDF–1.2M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Local Protease Signaling Contributes to Neural Tube Closure in the Mouse Embryo
Eric Camerer, Adrian Barker, Daniel N. Duong, Rajkumar Ganesan, Hiroshi Kataoka, Ivo Cornelissen, Molly R. Darragh, Arif Hussain, Yao-Wu Zheng, Yoga Srinivasan, Christopher Brown, Shan-Mei Xu, Jean B. Regard, Chen-Yong Lin, Charles S. Craik, Daniel Kirchhofer, Shaun R. Coughlin
Dev Cell. Author manuscript; available in PMC 2011 Jan 19.
Published in final edited form as: Dev Cell. 2010 Jan 19; 18(1): 25. doi: 10.1016/j.devcel.2009.11.014
PMCID:
PMC2822780
AbstractArticlePDF–3.8M

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