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Select item 113473781.

In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis

Ngoc Tung Tran, Robin Graf, Ernesto Acevedo-Ochoa, Janine Trombke, Timm Weber, Thomas Sommermann, Claudia Salomon, Ralf Kühn, Klaus Rajewsky, Van Trung Chu

Leukemia. 2024; 38(9): 2003–2015. Published online 2024 Jul 23. doi: 10.1038/s41375-024-02357-w

PMCID:: PMC11347378

Abstract Article PDF–5.0M

Select item 113273672.

Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis

Stephen Huang, Casie Reed, Melissa Ilsley, Graham Magor, Michael Tallack, Michael Landsberg, Helen Mitchell, Kevin Gillinder, Andrew Perkins

Nat Commun. 2024; 15: 7019. Published online 2024 Aug 15. doi: 10.1038/s41467-024-50579-4

PMCID:: PMC11327367

Abstract Article PDF–4.2M

Select item 111135493.

In vivo genome-wide binding of Id2 to E2F4 target genes as part of a reversible program in mice liver

Ivan Ferrer-Vicens, Ángela L. Riffo‐Campos, Rosa Zaragozá, Concha García, Gerardo López-Rodas, Juan R. Viña, Luis Torres, Elena R. García-Trevijano

Cell Mol Life Sci. 2014 Sep; 71(18): 3583–3597. Published online 2014 Feb 28. doi: 10.1007/s00018-014-1588-1

PMCID:: PMC11113549

Abstract Article PDF–2.1M

Select item 92337264.

Unveiling E2F4, TEAD1 and AP-1 as regulatory transcription factors of the replicative senescence program by multi-omics analysis

Yuting Wang, Liping Liu, Yifan Song, Xiaojie Yu, Hongkui Deng

Protein Cell. 2022 Oct; 13(10): 742–759. Published online 2022 Jan 12. doi: 10.1007/s13238-021-00894-z

PMCID:: PMC9233726

Abstract Article PDF–5.6M

Select item 90160565.

A Mutant Variant of E2F4 Triggers Multifactorial Therapeutic Effects in 5xFAD Mice

Noelia López-Sánchez, Morgan Ramón-Landreau, Cristina Trujillo, Alberto Garrido-García, José M. Frade

Mol Neurobiol. 2022; 59(5): 3016–3039. Published online 2022 Mar 7. doi: 10.1007/s12035-022-02764-z

PMCID:: PMC9016056

Abstract Article PDF–12M

Select item 85641176.

Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons

Remi Akagawa, Yo-ichi Nabeshima, Takeshi Kawauchi

Front Cell Dev Biol. 2021; 9: 753175. Published online 2021 Oct 20. doi: 10.3389/fcell.2021.753175

PMCID:: PMC8564117

Abstract Article PDF–2.2M

Select item 66736497.

Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation

Maria C. Cuitiño, Thierry Pécot, Daokun Sun, Raleigh Kladney, Takayuki Okano-Uchida, Neelam Shinde, Resham Saeed, Antonio J. Perez-Castro, Amy Webb, Tom Liu, Soo In Bae, Linda Clijsters, Nicholas Selner, Vincenzo Coppola, Cynthia Timmers, Michael C. Ostrowski, Michele Pagano, Gustavo Leone

Cell Rep. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: Cell Rep. 2019 Jun 18; 27(12): 3547–3560.e5. Published online 2019 May 23. doi: 10.1016/j.celrep.2019.05.004

PMCID:: PMC6673649

Abstract Article PDF–3.3M

Select item 66722618.

Cell Cycle Regulator E2F4 Is Essential for the Development of the Ventral Telencephalon

Vladimir A. Ruzhynsky, Kelly A. McClellan, Jacqueline L. Vanderluit, Yongsu Jeong, Marosh Furimsky, David S. Park, Douglas J. Epstein, Valerie A. Wallace, Ruth S. Slack

J Neurosci. 2007 May 30; 27(22): 5926–5935. doi: 10.1523/JNEUROSCI.1538-07.2007

PMCID:: PMC6672261

Abstract Article PDF–505K

Select item 66106669.

E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family

Jenny Hsu, Julia Arand, Andrea Chaikovsky, Nancie A. Mooney, Janos Demeter, Caileen M. Brison, Romane Oliverio, Hannes Vogel, Seth M. Rubin, Peter K. Jackson, Julien Sage

Nat Commun. 2019; 10: 2939. Published online 2019 Jul 3. doi: 10.1038/s41467-019-10901-x

PMCID:: PMC6610666

Abstract Article PDF–2.0M

Select item 654485010.

The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors

Tianwen Huang, Yasmilde Rodríguez González, Dianbo Qu, En Huang, Farzaneh Safarpour, Eugene Wang, Alvin Joselin, Doo Soon Im, Steve M. Callaghan, Wassamon Boonying, Lisa Julian, Sally L. Dunwoodie, Ruth S. Slack, David S. Park

J Biol Chem. 2019 May 24; 294(21): 8617–8629. Published online 2019 Apr 9. doi: 10.1074/jbc.RA119.007941

PMCID:: PMC6544850

Abstract Article PDF–2.6M

Select item 550089111.

Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis

Munemasa Mori, Renin Hazan, Paul S. Danielian, John E. Mahoney, Huijun Li, Jining Lu, Emily S. Miller, Xueliang Zhu, Jacqueline A. Lees, Wellington V. Cardoso

Nat Commun. 2017; 8: 15857. Published online 2017 Jul 4. doi: 10.1038/ncomms15857

Correction in:: Nat Commun. 2018; 9: 16157.

PMCID:: PMC5500891

Abstract Article PDF–2.5M

Select item 534277212.

Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development

Clotilde Costa, Mirentxu Santos, Mónica Martínez-Fernández, Corina Lorz, Sara Lázaro, Jesús M. Paramio

Oncotarget. 2016 Nov 15; 7(46): 75712–75728. Published online 2016 Sep 30. doi: 10.18632/oncotarget.12362

Correction in:: Oncotarget. 2017 Jul 25; 8(30): 50324.

PMCID:: PMC5342772

Abstract Article PDF–12M

Select item 482584013.

E2f4 and E2f5 are essential for the development of the male reproductive system

Paul S. Danielian, Rex A. Hess, Jacqueline A. Lees

Cell Cycle. 2016; 15(2): 250–260. Published online 2016 Jan 29. doi: 10.1080/15384101.2015.1121350

PMCID:: PMC4825840

Abstract Article PDF–1.7M

Select item 431955914.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 428250715.

Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells

Wayne O Miles, Michael Korenjak, Lyra M Griffiths, Michael A Dyer, Paolo Provero, Nicholas J Dyson

EMBO J. 2014 Oct 1; 33(19): 2201–2215. Published online 2014 Aug 7. doi: 10.15252/embj.201488057

PMCID:: PMC4282507

Abstract Article PDF–2.1M

Select item 418125216.

Krüppel-like transcription factors KLF1 and KLF2 have unique and coordinate roles in regulating embryonic erythroid precursor maturation

Divya S. Vinjamur, Kristen J. Wade, Safa F. Mohamad, Jack L. Haar, Stephen T. Sawyer, Joyce A. Lloyd

Haematologica. 2014 Oct; 99(10): 1565–1573. doi: 10.3324/haematol.2014.104943

PMCID:: PMC4181252

Abstract Article PDF–37M

Select item 414029517.

Regulation of Ischemic Neuronal Death by E2F4-p130 Protein Complexes

Grace O. Iyirhiaro, Yi Zhang, Carmen Estey, Michael J. O'Hare, Farzaneh Safarpour, Mohammad Parsanejad, Suzi Wang, Elizabeth Abdel-Messih, Steve M. Callaghan, Matthew J. During, Ruth S. Slack, David S. Park

J Biol Chem. 2014 Jun 27; 289(26): 18202–18213. Published online 2014 May 14. doi: 10.1074/jbc.M114.574145

PMCID:: PMC4140295

Abstract Article PDF–1.5M

Select item 393142218.

pRB and E2F4 play distinct cell-intrinsic roles in fetal erythropoiesis

Jing Zhang, Eunice Y. Lee, Yangang Liu, Seth D. Berman, Harvey F. Lodish, Jacqueline A. Lees

Cell Cycle. Author manuscript; available in PMC 2014 Feb 21.

Published in final edited form as: Cell Cycle. 2010 Jan 15; 9(2): 371–376. Published online 2010 Jan 29. doi: 10.4161/cc.9.2.10467

PMCID:: PMC3931422

Abstract Article PDF–966K

Select item 361648719.

Canonical and Atypical E2Fs Regulate the Mammalian Endocycle

Hui-Zi Chen, Madhu M. Ouseph, Jing Li, Thierry Pécot, Veda Chokshi, Lindsey Kent, Sooin Bae, Morgan Byrne, Camille Duran, Grant Comstock, Prashant Trikha, Markus Mair, Shantibhusan Senapati, Chelsea K. Martin, Sagar Gandhi, Nicholas Wilson, Bin Liu, Yi-Wen Huang, John C. Thompson, Sundaresan Raman, Shantanu Singh, Marcelo Leone, Raghu Machiraju, Kun Huang, Xiaokui Mo, Soledad Fernandez, Ilona Kalaszczynska, Debra J. Wolgemuth, Piotr Sicinski, Tim Huang, Victor Jin, Gustavo Leone

Nat Cell Biol. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Nat Cell Biol. 2012 Nov; 14(11): 1192–1202. Published online 2012 Oct 14. doi: 10.1038/ncb2595

PMCID:: PMC3616487

Abstract Article PDF–3.6M

Select item 361555320.

Patterns of cell signaling pathway activation that characterize mammary development

Eran R. Andrechek, Seiichi Mori, Rachel E. Rempel, Jeffrey T. Chang, Joseph R. Nevins

Development. Author manuscript; available in PMC 2013 Apr 3.

Published in final edited form as: Development. 2008 Aug; 135(14): 2403–2413. Published online 2008 Jun 11. doi: 10.1242/dev.019018

PMCID:: PMC3615553

Abstract Article PDF–5.2M

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