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Items: 1 to 20 of 33

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Early-onset tufting enteropathy in HAI-2-deficient mice is independent of matriptase-mediated cleavage of EpCAM
Roman Szabo, Makiko Kawaguchi, Hiroaki Kataoka, Thomas H. Bugge
Development. 2023 Sep 1; 150(17): dev201801. Published online 2023 Aug 31. doi: 10.1242/dev.201801
PMCID:
PMC10482385
AbstractArticle
3.
Little skate genome provides insights into genetic programs essential for limb-based locomotion
DongAhn Yoo, Junhee Park, Chul Lee, Injun Song, Young Ho Lee, Tery Yun, Hyemin Lee, Adriana Heguy, Jae Yong Han, Jeremy S Dasen, Heebal Kim, Myungin Baek
eLife. 2022; 11: e78345. Published online 2022 Oct 26. doi: 10.7554/eLife.78345
PMCID:
PMC9605692
AbstractArticlePDF–8.4M
4.
Protease‐activated receptor‐2 accelerates intestinal tumor formation through activation of nuclear factor‐κB signaling and tumor angiogenesis in ApcMin/+ mice
Makiko Kawaguchi, Koji Yamamoto, Hiroaki Kataoka, Aya Izumi, Fumiki Yamashita, Takumi Kiwaki, Takahiro Nishida, Eric Camerer, Tsuyoshi Fukushima
Cancer Sci. 2020 Apr; 111(4): 1193–1202. Published online 2020 Feb 24. doi: 10.1111/cas.14335
PMCID:
PMC7156842
AbstractArticlePDF–1.5M
5.
A Grhl2-dependent gene network controls trophoblast branching morphogenesis
Katharina Walentin, Christian Hinze, Max Werth, Nadine Haase, Saaket Varma, Robert Morell, Annekatrin Aue, Elisabeth Pötschke, David Warburton, Andong Qiu, Jonathan Barasch, Bettina Purfürst, Christoph Dieterich, Elena Popova, Michael Bader, Ralf Dechend, Anne Cathrine Staff, Zeliha Yesim Yurtdas, Ergin Kilic, Kai M. Schmidt-Ott
Development. 2015 Mar 15; 142(6): 1125–1136. Published online 2015 Mar 10. doi: 10.1242/dev.113829
PMCID:
PMC6517833
AbstractArticle
6.
TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1
Pawel Zmora, Markus Hoffmann, Heike Kollmus, Anna-Sophie Moldenhauer, Olga Danov, Armin Braun, Michael Winkler, Klaus Schughart, Stefan Pöhlmann
J Biol Chem. 2018 Sep 7; 293(36): 13863–13873. Published online 2018 Jul 5. doi: 10.1074/jbc.RA118.001273
PMCID:
PMC6130959
AbstractArticlePDF–1.9M
7.
Hepatocyte Growth Factor Activator Inhibitor Type 1 Maintains the Assembly of Keratin into Desmosomes in Keratinocytes by Regulating Protease-Activated Receptor 2–Dependent p38 Signaling
Makiko Kawaguchi, Ai Kanemaru, Akira Sawaguchi, Koji Yamamoto, Takashi Baba, Chen-Yong Lin, Michael D. Johnson, Tsuyoshi Fukushima, Hiroaki Kataoka
Am J Pathol. 2015 Jun; 185(6): 1610–1623. doi: 10.1016/j.ajpath.2015.02.009
PMCID:
PMC5707200
AbstractArticlePDF–3.4M
8.
Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the ApcMin/+ model
Makiko Kawaguchi, Koji Yamamoto, Ai Kanemaru, Hiroyuki Tanaka, Kazuo Umezawa, Tsuyoshi Fukushima, Hiroaki Kataoka
Oncotarget. 2016 Oct 18; 7(42): 68614–68622. Published online 2016 Sep 6. doi: 10.18632/oncotarget.11863
PMCID:
PMC5356577
AbstractArticlePDF–8.2M
9.
Delineation of proteolytic and non-proteolytic functions of the membrane-anchored serine protease prostasin
Roman Szabo, Taliya Lantsman, Diane E. Peters, Thomas H. Bugge
Development. 2016 Aug 1; 143(15): 2818–2828. doi: 10.1242/dev.137968
PMCID:
PMC5004911
AbstractArticle
10.
Crystal Structure of a Two-domain Fragment of Hepatocyte Growth Factor Activator Inhibitor-1: FUNCTIONAL INTERACTIONS BETWEEN THE KUNITZ-TYPE INHIBITOR DOMAIN-1 AND THE NEIGHBORING POLYCYSTIC KIDNEY DISEASE-LIKE DOMAIN
Zebin Hong, Laura De Meulemeester, Annemarie Jacobi, Jan Skov Pedersen, J. Preben Morth, Peter A. Andreasen, Jan K. Jensen
J Biol Chem. 2016 Jul 1; 291(27): 14340–14355. Published online 2016 May 6. doi: 10.1074/jbc.M115.707240
PMCID:
PMC4933187
AbstractArticlePDF–3.4M
11.
Hepatocyte Growth Factor Activator Inhibitor-1 has a Complex Subcellular Itinerary
Sine Godiksen, Joanna Selzer-Plon, Esben D.K. Pedersen, Kathrine Abell, Hanne B. Rasmussen, Roman Szabo, Thomas H. Bugge, Lotte K. Vogel
Biochem J. Author manuscript; available in PMC 2016 Apr 1.
Published in final edited form as: Biochem J. 2008 Jul 15; 413(2): 251–259. doi: 10.1042/BJ20071496
PMCID:
PMC4816720
AbstractArticlePDF–504K
12.
The Protease Inhibitor HAI-2, but Not HAI-1, Regulates Matriptase Activation and Shedding through Prostasin
Stine Friis, Katiuchia Uzzun Sales, Jeffrey Martin Schafer, Lotte K. Vogel, Hiroaki Kataoka, Thomas H. Bugge
J Biol Chem. 2014 Aug 8; 289(32): 22319–22332. Published online 2014 Jun 24. doi: 10.1074/jbc.M114.574400
PMCID:
PMC4139241
AbstractArticlePDF–4.6M
13.
PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation
Constantinos M. Mikelis, Todd R. Palmby, May Simaan, Wenling Li, Roman Szabo, Ruth Lyons, Daniel Martin, Hiroshi Yagi, Shigetomo Fukuhara, Hiroki Chikumi, Rebeca Galisteo, Yoh-suke Mukouyama, Thomas H. Bugge, J. Silvio Gutkind
J Biol Chem. 2013 Apr 26; 288(17): 12232–12243. Published online 2013 Mar 6. doi: 10.1074/jbc.M112.428599
PMCID:
PMC3636907
AbstractArticlePDF–3.7M
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
Hepatocyte Growth Factor Activator Inhibitor-1 Is Induced by Bone Morphogenetic Proteins and Regulates Proliferation and Cell Fate of Neural Progenitor Cells
Raili Koivuniemi, Johanna Mäkelä, Marie-Estelle Hokkanen, Céline Bruelle, Tho Huu Ho, Roxana Ola, Laura Korhonen, Jim Schröder, Hiroaki Kataoka, Dan Lindholm
PLoS One. 2013; 8(2): e56117. Published online 2013 Feb 7. doi: 10.1371/journal.pone.0056117
PMCID:
PMC3567048
AbstractArticlePDF–5.7M
16.
Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency–Associated Developmental Defects by Preventing Matriptase Activation
Roman Szabo, Katiuchia Uzzun Sales, Peter Kosa, Natalia A. Shylo, Sine Godiksen, Karina K. Hansen, Stine Friis, J. Silvio Gutkind, Lotte K. Vogel, Edith Hummler, Eric Camerer, Thomas H. Bugge
PLoS Genet. 2012 Aug; 8(8): e1002937. Published online 2012 Aug 30. doi: 10.1371/journal.pgen.1002937
PMCID:
PMC3431340
AbstractArticlePDF–4.6M
17.
Membrane-Bound Serine Protease Inhibitor HAI-1 Is Required for Maintenance of Intestinal Epithelial Integrity
Makiko Kawaguchi, Naoki Takeda, Shinri Hoshiko, Kenji Yorita, Takashi Baba, Akira Sawaguchi, Yuriko Nezu, Tsutomu Yoshikawa, Tsuyoshi Fukushima, Hiroaki Kataoka
Am J Pathol. 2011 Oct; 179(4): 1815–1826. doi: 10.1016/j.ajpath.2011.06.038
PMCID:
PMC3181355
AbstractArticlePDF–5.0M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Membrane-type MMPs are indispensable for placental labyrinth formation and development
Ludmila Szabova, Mee-Young Son, Joanne Shi, Marek Sramko, Susan S. Yamada, William D. Swaim, Patricia Zerfas, Stacie Kahan, Kenn Holmbeck
Blood. 2010 Dec 16; 116(25): 5752–5761. Prepublished online 2010 Sep 21. doi: 10.1182/blood-2009-10-249847
PMCID:
PMC3031418
AbstractArticle
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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