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Items: 1 to 20 of 60

1.
The Kir2.1E299V mutation increases atrial fibrillation vulnerability while protecting the ventricles against arrhythmias in a mouse model of short QT syndrome type 3
Ana I Moreno-Manuel, Álvaro Macías, Francisco M Cruz, Lilian K Gutiérrez, Fernando Martínez, Andrés González-Guerra, Isabel Martínez Carrascoso, Francisco José Bermúdez-Jimenez, Patricia Sánchez-Pérez, María Linarejos Vera-Pedrosa, Juan Manuel Ruiz-Robles, Juan A Bernal, José Jalife
Cardiovasc Res. 2024 Apr; 120(5): 490–505. Published online 2024 Jan 23. doi: 10.1093/cvr/cvae019
PMCID:
PMC11060485
AbstractArticlePDF–1.5M
2.
Hypothalamic POMC neuron-specific knockout of MC4R affects insulin sensitivity by regulating Kir2.1
Hengru Guo, Ying Xin, Saifei Wang, Xiaoning Zhang, Yanqi Ren, Bo Qiao, Hongjiang Li, Jing Wu, Xiao Hao, Lijun Xu, Yushan Yan, Haohao Zhang
Mol Med. 2024; 30: 34. Published online 2024 Mar 6. doi: 10.1186/s10020-024-00804-z
PMCID:
PMC10918880
AbstractArticlePDF–6.4M
3.
Single-cell, whole-embryo phenotyping of mammalian developmental disorders
Xingfan Huang, Jana Henck, Chengxiang Qiu, Varun K. A. Sreenivasan, Saranya Balachandran, Oana V. Amarie, Martin Hrabě de Angelis, Rose Yinghan Behncke, Wing-Lee Chan, Alexandra Despang, Diane E. Dickel, Madeleine Duran, Annette Feuchtinger, Helmut Fuchs, Valerie Gailus-Durner, Natja Haag, Rene Hägerling, Nils Hansmeier, Friederike Hennig, Cooper Marshall, Sudha Rajderkar, Alessa Ringel, Michael Robson, Lauren M. Saunders, Patricia da Silva-Buttkus, Nadine Spielmann, Sanjay R. Srivatsan, Sascha Ulferts, Lars Wittler, Yiwen Zhu, Vera M. Kalscheuer, Daniel M. Ibrahim, Ingo Kurth, Uwe Kornak, Axel Visel, Len A. Pennacchio, David R. Beier, Cole Trapnell, Junyue Cao, Jay Shendure, Malte Spielmann
Nature. 2023; 623(7988): 772–781. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06548-w
PMCID:
PMC10665194
AbstractArticlePDF–23M
4.
Forebrain E-I balance controlled in cognition through coordinated inhibition and inhibitory transcriptome mechanism
Tian Tian, You Cai, Xin Qin, Jiangang Wang, Yali Wang, Xin Yang
Front Cell Neurosci. 2023; 17: 1114037. Published online 2023 Feb 24. doi: 10.3389/fncel.2023.1114037
PMCID:
PMC10000298
AbstractArticlePDF–8.3M
5.
Understanding the development of oral epithelial organs through single cell transcriptomic analysis
Qianlin Ye, Arshia Bhojwani, Jimmy K. Hu
Development. 2022 Aug 15; 149(16): dev200539. Published online 2022 Aug 17. doi: 10.1242/dev.200539
PMCID:
PMC9481975
AbstractArticle
6.
Alzheimer's disease and cerebrovascular pathology alter inward rectifier potassium (KIR2.1) channels in endothelium of mouse cerebral arteries
María Lacalle‐Aurioles, Lianne J. Trigiani, Miled Bourourou, Clotilde Lecrux, Edith Hamel
Br J Pharmacol. 2022 May; 179(10): 2259–2274. Published online 2022 Feb 10. doi: 10.1111/bph.15751
Correction in:
Br J Pharmacol. 2022 Sep; 179(17): 4458.
PMCID:
PMC9304142
AbstractArticlePDF–10M
7.
Cholesterol-induced suppression of endothelial Kir channels is a driver of impairment of arteriolar flow-induced vasodilation in humans
Sang Joon Ahn, Ibra S. Fancher, Sara T. Granados, Natalia F. Do Couto, Chueh-Lung Hwang, Shane A. Phillips, Irena Levitan
Hypertension. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Hypertension. 2022 Jan; 79(1): 126–138. Published online 2021 Nov 17. doi: 10.1161/HYPERTENSIONAHA.121.17672
PMCID:
PMC8845492
AbstractArticlePDF–1.7M
8.
PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity
Fabrice Dabertrand, Osama F. Harraz, Masayo Koide, Thomas A. Longden, Amanda C. Rosehart, David C. Hill-Eubanks, Anne Joutel, Mark T. Nelson
Proc Natl Acad Sci U S A. 2021 Apr 27; 118(17): e2025998118. Published online 2021 Apr 19. doi: 10.1073/pnas.2025998118
PMCID:
PMC8092380
AbstractArticlePDF–2.8M
9.
Potassium Channels Kv1.3 and Kir2.1 But Not Kv1.5 Contribute to BV2 Cell Line and Primary Microglial Migration
Ruxandra Anton, Mihail Ghenghea, Violeta Ristoiu, Christophe Gattlen, Marc-Rene Suter, Petre Alexandru Cojocaru, Aurel Popa-Wagner, Bogdan Catalin, Alexandru-Florian Deftu
Int J Mol Sci. 2021 Feb; 22(4): 2081. Published online 2021 Feb 19. doi: 10.3390/ijms22042081
PMCID:
PMC7923211
AbstractArticlePDF–3.0M
10.
Genetic Loss of IK1 Causes Adrenergic-induced Phase 3 Early Afterdepolarizations and Polymorphic and Bi-directional Ventricular Tachycardia
Louise Reilly, Francisco J. Alvarado, Di Lang, Sara Abozeid, Hannah Van Ert, Cordell Spellman, Jarrett Warden, Jonathan C. Makielski, Alexey V. Glukhov, Lee L. Eckhardt
Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2020 Sep; 13(9): e008638. Published online 2020 Aug 4. doi: 10.1161/CIRCEP.120.008638
PMCID:
PMC7574954
AbstractArticlePDF–2.2M
11.
Impairment of flow-sensitive inwardly rectifying K+ channels via disruption of glycocalyx mediates obesity-induced endothelial dysfunction
Ibra S. Fancher, Elizabeth Le Master, Sang Joon Ahn, Crystal Adamos, James C. Lee, Evgeny Berdyshev, Randal O. Dull, Shane A. Phillips, Irena Levitan
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2020 Sep; 40(9): e240–e255. Published online 2020 Jul 23. doi: 10.1161/ATVBAHA.120.314935
PMCID:
PMC7503211
AbstractArticlePDF–2.2M
12.
In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix
Jiyoung Lee, Akito Sutani, Rin Kaneko, Jun Takeuchi, Tetsuo Sasano, Takashi Kohda, Kensuke Ihara, Kentaro Takahashi, Masahiro Yamazoe, Tomohiro Morio, Tetsushi Furukawa, Fumitoshi Ishino
Nat Commun. 2020; 11: 4283. Published online 2020 Sep 3. doi: 10.1038/s41467-020-18031-5
PMCID:
PMC7471119
AbstractArticlePDF–10M
13.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
14.
The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K+-mediated neurovascular communication
Arash Moshkforoush, Baarbod Ashenagar, Osama F. Harraz, Fabrice Dabertrand, Thomas A. Longden, Mark T. Nelson, Nikolaos M. Tsoukias
Proc Natl Acad Sci U S A. 2020 Jul 14; 117(28): 16626–16637. Published online 2020 Jun 29. doi: 10.1073/pnas.2000151117
PMCID:
PMC7368319
AbstractArticlePDF–7.0M
15.
Neuronal Interleukin-16 (NIL-16): A Dual Function PDZ Domain Protein
Cornelia Kurschner, Michisuke Yuzaki
J Neurosci. 1999 Sep 15; 19(18): 7770–7780. doi: 10.1523/JNEUROSCI.19-18-07770.1999
PMCID:
PMC6782450
AbstractArticlePDF–604K
16.
Kir2.1 Channel Regulation of Glycinergic Transmission Selectively Contributes to Dynamic Mechanical Allodynia in a Mouse Model of Spared Nerve Injury
Yiqian Shi, Yangyang Chen, Yun Wang
Neurosci Bull. 2019 Apr; 35(2): 301–314. Published online 2018 Sep 11. doi: 10.1007/s12264-018-0285-8
PMCID:
PMC6426903
AbstractArticlePDF–1.4M
17.
PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells
Osama F Harraz, Thomas A Longden, David Hill-Eubanks, Mark T Nelson
eLife. 2018; 7: e38689. Published online 2018 Aug 7. doi: 10.7554/eLife.38689
PMCID:
PMC6117155
AbstractArticlePDF–5.0M
18.
The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors
Luca Caputo, Hagen R. Witzel, Petros Kolovos, Sirisha Cheedipudi, Mario Looso, Athina Mylona, Wilfred F.J. van IJcken, Karl-Ludwig Laugwitz, Sylvia M. Evans, Thomas Braun, Eric Soler, Frank Grosveld, Gergana Dobreva
Cell Stem Cell. Author manuscript; available in PMC 2018 Mar 27.
Published in final edited form as: Cell Stem Cell. 2015 Sep 3; 17(3): 287–299. Published online 2015 Aug 27. doi: 10.1016/j.stem.2015.08.007
PMCID:
PMC5870759
AbstractArticlePDF–2.5M
19.
Hypercholesterolemia‐Induced Loss of Flow‐Induced Vasodilation and Lesion Formation in Apolipoprotein E–Deficient Mice Critically Depend on Inwardly Rectifying K+ Channels
Ibra S. Fancher, Sang Joon Ahn, Crystal Adamos, Catherine Osborn, Myung‐Jin Oh, Yun Fang, Catherine A. Reardon, Godfrey S. Getz, Shane A. Phillips, Irena Levitan
J Am Heart Assoc. 2018 Mar 6; 7(5): e007430. Published online 2018 Mar 3. doi: 10.1161/JAHA.117.007430
PMCID:
PMC5866319
AbstractArticlePDF–1.1M
20.
Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model
Amir Toib, Chen Zhang, Giulia Borghetti, Xiaoxiao Zhang, Markus Wallner, Yijun Yang, Constantine D. Troupes, Hajime Kubo, Thomas E. Sharp, Eric Feldsott, Remus M. Berretta, Neil Zalavadia, Danielle M. Trappanese, Shavonn Harper, Polina Gross, Xiongwen Chen, Sadia Mohsin, Steven R. Houser
Am J Physiol Heart Circ Physiol. 2017 Sep 1; 313(3): H620–H630. Published online 2017 Jun 23. doi: 10.1152/ajpheart.00167.2017
PMCID:
PMC5625176
AbstractArticle

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