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Items: 1 to 20 of 32

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory
Yujiro Kidani, Wataru Nogami, Yoshiaki Yasumizu, Atsunari Kawashima, Atsushi Tanaka, Yudai Sonoda, Yumi Tona, Kunitaka Nashiki, Reimi Matsumoto, Masaki Hagiwara, Motonao Osaki, Keiji Dohi, Takayuki Kanazawa, Azumi Ueyama, Mai Yoshikawa, Tetsuya Yoshida, Mitsunobu Matsumoto, Kanji Hojo, Satomi Shinonome, Hiroshi Yoshida, Michinari Hirata, Miya Haruna, Yamami Nakamura, Daisuke Motooka, Daisuke Okuzaki, Yasuko Sugiyama, Makoto Kinoshita, Tatsusada Okuno, Taigo Kato, Koji Hatano, Motohide Uemura, Ryoichi Imamura, Kazunori Yokoi, Atsushi Tanemura, Yasushi Shintani, Tadashi Kimura, Norio Nonomura, Hisashi Wada, Masaki Mori, Yuichiro Doki, Naganari Ohkura, Shimon Sakaguchi
Proc Natl Acad Sci U S A. 2022 Feb 15; 119(7): e2114282119. Published online 2022 Feb 9. doi: 10.1073/pnas.2114282119
PMCID:
PMC8851483
AbstractArticlePDF–2.5M
3.
Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4+ T Cell Activation and Mycobacterium tuberculosis Control
Shibali Das, Nancy D. Marin, Ekaterina Esaulova, Mushtaq Ahmed, Amanda Swain, Bruce A. Rosa, Makedonka Mitreva, Javier Rangel-Moreno, Mihai G. Netea, Luis B. Barreiro, Maziar Divangahi, Maxim N. Artyomov, Deepak Kaushal, Shabaana A. Khader
mBio. 2021 Jul-Aug; 12(4): e01468-21. Published online 2021 Jul 13. doi: 10.1128/mBio.01468-21
PMCID:
PMC8406195
AbstractArticlePDF–4.7M
4.
Pathogenic roles and therapeutic potential of the CCL8–CCR8 axis in a murine model of IgG4-related sialadenitis
Fumika Honda, Hiroto Tsuboi, Yuko Ono, Saori Abe, Hiroyuki Takahashi, Kiyoaki Ito, Kazunori Yamada, Mitsuhiro Kawano, Yuya Kondo, Kenichi Asano, Masato Tanaka, Marie Malissen, Bernard Malissen, Isao Matsumoto, Takayuki Sumida
Arthritis Res Ther. 2021; 23: 214. Published online 2021 Aug 14. doi: 10.1186/s13075-021-02597-6
PMCID:
PMC8364087
AbstractArticlePDF–2.2M
5.
CCR8 Signaling via CCL1 Regulates Responses of Intestinal IFN-γ Producing Innate Lymphoid CelIs and Protects From Experimental Colitis
Le Kang, Angelika Schmalzl, Tamara Leupold, Miguel Gonzalez-Acera, Raja Atreya, Markus F. Neurath, Christoph Becker, Stefan Wirtz
Front Immunol. 2020; 11: 609400. Published online 2021 Feb 5. doi: 10.3389/fimmu.2020.609400
PMCID:
PMC7892458
AbstractArticlePDF–5.1M
6.
Efficient homing of T cells via afferent lymphatics requires mechanical arrest and integrin-supported chemokine guidance
Rieke Martens, Marc Permanyer, Kathrin Werth, Kai Yu, Asolina Braun, Olga Halle, Stephan Halle, Gwendolyn E. Patzer, Berislav Bošnjak, Friedemann Kiefer, Anika Janssen, Michaela Friedrichsen, Jenny Poetzsch, Karan Kohli, Yvonne Lueder, Rodrigo Gutierrez Jauregui, Nadine Eckert, Tim Worbs, Melanie Galla, Reinhold Förster
Nat Commun. 2020; 11: 1114. Published online 2020 Feb 28. doi: 10.1038/s41467-020-14921-w
PMCID:
PMC7048855
AbstractArticlePDF–5.4M
7.
A CCL1/CCR8-dependent feed-forward mechanism drives ILC2 functions in type 2–mediated inflammation
Lisa Knipfer, Anja Schulz-Kuhnt, Markus Kindermann, Vicky Greif, Cornelia Symowski, David Voehringer, Markus F. Neurath, Imke Atreya, Stefan Wirtz
J Exp Med. 2019 Dec 2; 216(12): 2763–2777. Published online 2019 Sep 19. doi: 10.1084/jem.20182111
PMCID:
PMC6888976
AbstractArticlePDF–3.0M
8.
CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis
Frank Blanco-Pérez, Yoichiro Kato, Irene Gonzalez-Menendez, Jonathan Laiño, Masaharu Ohbayashi, Manja Burggraf, Maren Krause, Jörg Kirberg, Yoichiro Iwakura, Manuela Martella, Leticia Quintanilla-Martinez, Noriyuki Shibata, Stefan Vieths, Stephan Scheurer, Masako Toda
Sci Rep. 2019; 9: 9608. Published online 2019 Jul 3. doi: 10.1038/s41598-019-45653-7
PMCID:
PMC6610106
AbstractArticlePDF–2.5M
9.
The chemokine receptor CCR8 promotes the migration of dendritic cells into the lymph node parenchyma to initiate the allergic immune response.
Caroline L. Sokol, Ryan B. Camire, Michael C. Jones, Andrew D. Luster
Immunity. Author manuscript; available in PMC 2019 Sep 18.
Published in final edited form as: Immunity. 2018 Sep 18; 49(3): 449–463.e6. Published online 2018 Aug 28. doi: 10.1016/j.immuni.2018.07.012
PMCID:
PMC6192021
AbstractArticlePDF–1.4M
10.
CCR8 is expressed by post-positive selection CD4-lineage thymocytes but is dispensable for central tolerance induction
Hiran M. Thyagarajan, Jessica N. Lancaster, Sergio A. Lira, Lauren I. R. Ehrlich
PLoS One. 2018; 13(7): e0200765. Published online 2018 Jul 19. doi: 10.1371/journal.pone.0200765
PMCID:
PMC6053179
AbstractArticlePDF–21M
11.
CCR8+FOXp3+ Treg cells as master drivers of immune regulation
Yiftah Barsheshet, Gizi Wildbaum, Eran Levy, Alon Vitenshtein, Chika Akinseye, Jeremy Griggs, Sergio A. Lira, Nathan Karin
Proc Natl Acad Sci U S A. 2017 Jun 6; 114(23): 6086–6091. Published online 2017 May 22. doi: 10.1073/pnas.1621280114
PMCID:
PMC5468670
AbstractArticlePDF–1.0M
12.
DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease
Hidekazu Nishikii, Byung-Su Kim, Yasuhisa Yokoyama, Yan Chen, Jeanette Baker, Antonio Pierini, Maite Alvarez, Melissa Mavers, Kristina Maas-Bauer, Yuqiong Pan, Shigeru Chiba, Robert S. Negrin
Blood. 2016 Dec 15; 128(24): 2846–2858. Prepublished online 2016 Oct 19. doi: 10.1182/blood-2016-06-723783
PMCID:
PMC5159706
AbstractArticle
13.
Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation
Nicholas Collins, Xiaodong Jiang, Ali Zaid, Bethany L. Macleod, Jane Li, Chang Ook Park, Ashraful Haque, Sammy Bedoui, William R. Heath, Scott N. Mueller, Thomas S. Kupper, Thomas Gebhardt, Francis R. Carbone
Nat Commun. 2016; 7: 11514. Published online 2016 May 10. doi: 10.1038/ncomms11514
PMCID:
PMC4866325
AbstractArticlePDF–2.7M
14.
Interleukin-2-dependent allergen-specific tissue resident memory cells drive asthma
Brian D. Hondowicz, Dowon An, Jason M. Schenkel, Karen S. Kim, Holly R. Steach, Akshay T. Krishnamurty, Gladys J. Keitany, Esteban N. Garza, Kathryn A. Fraser, James J. Moon, William A. Altemeier, David Masopust, Marion Pepper
Immunity. Author manuscript; available in PMC 2017 Jan 19.
Published in final edited form as: Immunity. 2016 Jan 19; 44(1): 155–166. Published online 2015 Dec 29. doi: 10.1016/j.immuni.2015.11.004
PMCID:
PMC4720536
AbstractArticlePDF–1.6M
15.
IL-4/CCL22/CCR4 Axis Controls Regulatory T-Cell Migration That Suppresses Inflammatory Bone Loss in Murine Experimental Periodontitis
Ana Claudia Araujo-Pires, Andreia Espindola Vieira, Carolina Favaro Francisconi, Claudia Cristina Biguetti, Andrew Glowacki, Sayuri Yoshizawa, Ana Paula Campanelli, Ana Paula Favaro Trombone, Charles S. Sfeir, Steven R. Little, Gustavo Pompermaier Garlet
J Bone Miner Res. Author manuscript; available in PMC 2016 Mar 1.
Published in final edited form as: J Bone Miner Res. 2015 Mar; 30(3): 412–422. doi: 10.1002/jbmr.2376
PMCID:
PMC4542048
AbstractArticlePDF–883K
16.
Hepatic Macrophage Migration and Differentiation Critical for Liver Fibrosis Is Mediated by the Chemokine Receptor C-C Motif Chemokine Receptor 8 in Mice
Felix Heymann, Linda Hammerich, Dunja Storch, Matthias Bartneck, Sebastian Huss, Vanessa Rüsseler, Nikolaus Gassler, Sergio A. Lira, Tom Luedde, Christian Trautwein, Frank Tacke
Hepatology. Author manuscript; available in PMC 2015 Aug 12.
Published in final edited form as: Hepatology. 2012 Mar; 55(3): 898–909. Published online 2012 Jan 13. doi: 10.1002/hep.24764
PMCID:
PMC4533854
AbstractArticlePDF–818K
17.
Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin
Keisuke Nagao, Tetsuro Kobayashi, Kazuyo Moro, Manabu Ohyama, Takeya Adachi, Daniela Y Kitashima, Satoshi Ueha, Keisuke Horiuchi, Hideaki Tanizaki, Kenji Kabashima, Akiharu Kubo, Young-hun Cho, Björn E Clausen, Kouji Matsushima, Makoto Suematsu, Glaucia C Furtado, Sergio A Lira, Joshua M Farber, Mark C Udey, Masayuki Amagai
Nat Immunol. Author manuscript; available in PMC 2014 Jul 30.
Published in final edited form as: Nat Immunol. 2012 Aug; 13(8): 744–752. Published online 2012 Jun 24. doi: 10.1038/ni.2353
PMCID:
PMC4115277
AbstractArticlePDF–1.2M
18.
Chemokine Receptor CCR8 Is Required for Lipopolysaccharide-Triggered Cytokine Production in Mouse Peritoneal Macrophages
Tomoyuki Oshio, Rei Kawashima, Yuki I. Kawamura, Teruki Hagiwara, Noriko Mizutani, Toshihiko Okada, Takeshi Otsubo, Kyoko Inagaki-Ohara, Akihiro Matsukawa, Tatsuya Haga, Shigeru Kakuta, Yoichiro Iwakura, Seijiro Hosokawa, Taeko Dohi
PLoS One. 2014; 9(4): e94445. Published online 2014 Apr 8. doi: 10.1371/journal.pone.0094445
PMCID:
PMC3979852
AbstractArticlePDF–1.3M
19.
The transcriptional repressor BLIMP1 curbs host-defenses by suppressing expression of the chemokine CCL8
Martina Severa, Sabina A. Islam, Stephen N. Waggoner, Zhaozhao Jiang, Nancy D. Kim, Glennice Ryan, Evelyn Kurt-Jones, Israel Charo, Daniel R. Caffrey, Victor L. Boyartchuk, Andrew D. Luster, Katherine A. Fitzgerald
J Immunol. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: J Immunol. 2014 Mar 1; 192(5): 2291–2304. Published online 2014 Jan 29. doi: 10.4049/jimmunol.1301799
PMCID:
PMC3943885
AbstractArticlePDF–2.4M
20.
Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ TH2 cells
Sabina A Islam, Daniel S Chang, Richard A Colvin, Mike H Byrne, Michelle L McCully, Bernhard Moser, Sergio A Lira, Israel F Charo, Andrew D Luster
Nat Immunol. Author manuscript; available in PMC 2013 Dec 14.
Published in final edited form as: Nat Immunol. 2011 Feb; 12(2): 10.1038/ni.1984. Published online 2011 Jan 9. doi: 10.1038/ni.1984
PMCID:
PMC3863381
AbstractArticlePDF–1.9M

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