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Items: 1 to 20 of 42

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2
Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Violetta Steeples, Amar J. Azad, Evie Singer, Jasmeet S. Reyat, Frantisek Galatik, Elisabeth Ehler, Pauline Bennett, Jacinta I. Kalisch-Smith, Duncan B. Sparrow, Benjamin Davies, Kristina Djinovic-Carugo, Mathias Gautel, Hugh Watkins, Katja Gehmlich
Cells. 2023 Mar; 12(5): 721. Published online 2023 Feb 24. doi: 10.3390/cells12050721
PMCID:
PMC10001372
AbstractArticlePDF–2.7M
3.
Genetic Ablation of Ankrd1 Mitigates Cardiac Damage during Experimental Autoimmune Myocarditis in Mice
Ieva Rinkūnaitė, Egidijus Šimoliūnas, Milda Alksnė, Gabrielė Bartkutė, Siegfried Labeit, Virginija Bukelskienė, Julius Bogomolovas
Biomolecules. 2022 Dec; 12(12): 1898. Published online 2022 Dec 18. doi: 10.3390/biom12121898
PMCID:
PMC9775225
AbstractArticlePDF–2.7M
4.
Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate
Nour Abou Nader, Amélie Ménard, Adrien Levasseur, Guillaume St-Jean, Derek Boerboom, Gustavo Zamberlam, Alexandre Boyer
Int J Mol Sci. 2022 Nov; 23(21): 13585. Published online 2022 Nov 5. doi: 10.3390/ijms232113585
PMCID:
PMC9655313
AbstractArticlePDF–4.1M
5.
A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis
Chun-Hao Hung, Tung-Liang Lee, Anna Yu-Szu Huang, Kang-Chung Yang, Yu-Chiau Shyu, Shau-Ching Wen, Mu-Jie Lu, Shinsheng Yuan, Che-Kun James Shen
Int J Mol Sci. 2021 Aug; 22(15): 8024. Published online 2021 Jul 27. doi: 10.3390/ijms22158024
PMCID:
PMC8347936
AbstractArticlePDF–4.4M
6.
QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function
Xinyun Chen, Ying Liu, Chen Xu, Lina Ba, Zhuo Liu, Xiuya Li, Jie Huang, Ed Simpson, Hongyu Gao, Dayan Cao, Wei Sheng, Hanping Qi, Hongrui Ji, Maria Sanderson, Chen-Leng Cai, Xiaohui Li, Lei Yang, Jie Na, Kenichi Yamamura, Yunlong Liu, Guoying Huang, Weinian Shou, Ning Sun
Nat Commun. 2021; 12: 89. Published online 2021 Jan 4. doi: 10.1038/s41467-020-20327-5
PMCID:
PMC7782589
AbstractArticlePDF–8.6M
7.
The Planar Polarity Component VANGL2 Is a Key Regulator of Mechanosignaling
Sek-Shir Cheong, Khondoker M. Akram, Carlos Matellan, Sally Yunsun Kim, David C. A. Gaboriau, Matthew Hind, Armando E. del Río Hernández, Mark Griffiths, Charlotte H. Dean
Front Cell Dev Biol. 2020; 8: 577201. Published online 2020 Oct 29. doi: 10.3389/fcell.2020.577201
PMCID:
PMC7658195
AbstractArticlePDF–8.8M
8.
Myocardial-specific ablation of Jumonji and AT-rich interaction domain–containing 2 (Jarid2) leads to dilated cardiomyopathy in mice
Eunjin Cho, HyunJun Kang, Dae-Ki Kang, Youngsook Lee
J Biol Chem. 2019 Mar 29; 294(13): 4981–4996. Published online 2019 Jan 30. doi: 10.1074/jbc.RA118.005634
PMCID:
PMC6442036
AbstractArticlePDF–3.3M
9.
Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement
Guangshuai Jia, Jens Preussner, Xi Chen, Stefan Guenther, Xuejun Yuan, Michail Yekelchyk, Carsten Kuenne, Mario Looso, Yonggang Zhou, Sarah Teichmann, Thomas Braun
Nat Commun. 2018; 9: 4877. Published online 2018 Nov 19. doi: 10.1038/s41467-018-07307-6
PMCID:
PMC6242939
AbstractArticlePDF–6.6M
10.
Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5
Dilyana Filipova, Margit Henry, Tamara Rotshteyn, Anna Brunn, Mariana Carstov, Martina Deckert, Jürgen Hescheler, Agapios Sachinidis, Gabriele Pfitzer, Symeon Papadopoulos
PLoS One. 2018; 13(3): e0194428. Published online 2018 Mar 15. doi: 10.1371/journal.pone.0194428
PMCID:
PMC5854361
AbstractArticlePDF–29M
11.
YAP/TAZ and Hedgehog coordinate growth and patterning in gastrointestinal mesenchyme
Jennifer L. Cotton, Qi Li, Lifang Ma, Joo-Seop Park, Jiayi Wang, Jianhong Ou, Lihua J. Zhu, Y. Tony Ip, Randy L. Johnson, Junhao Mao
Dev Cell. Author manuscript; available in PMC 2018 Oct 9.
Published in final edited form as: Dev Cell. 2017 Oct 9; 43(1): 35–47.e4. Published online 2017 Sep 21. doi: 10.1016/j.devcel.2017.08.019
PMCID:
PMC5823011
AbstractArticlePDF–3.7M
12.
The histone code reader Spin1 controls skeletal muscle development
Holger Greschik, Delphine Duteil, Nadia Messaddeq, Dominica Willmann, Laura Arrigoni, Manuela Sum, Manfred Jung, Daniel Metzger, Thomas Manke, Thomas Günther, Roland Schüle
Cell Death Dis. 2017 Nov; 8(11): e3173. Published online 2017 Nov 23. doi: 10.1038/cddis.2017.468
PMCID:
PMC5775400
AbstractArticlePDF–6.2M
13.
Elastic force restricts growth of the murine utricle
Ksenia Gnedeva, Adrian Jacobo, Joshua D Salvi, Aleksandra A Petelski, A J Hudspeth
eLife. 2017; 6: e25681. Published online 2017 Jul 25. doi: 10.7554/eLife.25681
PMCID:
PMC5550282
AbstractArticlePDF–11M
14.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
15.
MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy
Stephan Lange, Katja Gehmlich, Alexander S. Lun, Jordan Blondelle, Charlotte Hooper, Nancy D. Dalton, Erika A. Alvarez, Xiaoyu Zhang, Marie-Louise Bang, Yama A. Abassi, Cristobal G. dos Remedios, Kirk L. Peterson, Ju Chen, Elisabeth Ehler
Nat Commun. 2016; 7: 12120. Published online 2016 Jun 29. doi: 10.1038/ncomms12120
PMCID:
PMC4931343
AbstractArticlePDF–2.2M
16.
LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development
Da-Hye Lee, Jae Oh Park, Tae-Shin Kim, Sang-Kyum Kim, Tack-hoon Kim, Min-chul Kim, Gun Soo Park, Jeong-Hwan Kim, Shinji Kuninaka, Eric N. Olson, Hideyuki Saya, Seon-Young Kim, Ho Lee, Dae-Sik Lim
Nat Commun. 2016; 7: 11961. Published online 2016 Jun 30. doi: 10.1038/ncomms11961
PMCID:
PMC4931324
AbstractArticlePDF–3.4M
17.
Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers
Giuseppina Mastrototaro, Xingqun Liang, Xiaodong Li, Pierluigi Carullo, Nicoletta Piroddi, Chiara Tesi, Yusu Gu, Nancy D. Dalton, Kirk L. Peterson, Corrado Poggesi, Farah Sheikh, Ju Chen, Marie-Louise Bang
Cardiovasc Res. 2015 Jul 15; 107(2): 216–225. Published online 2015 May 18. doi: 10.1093/cvr/cvv156
PMCID:
PMC4565986
AbstractArticle
18.
Targeted inhibition of ANKRD1 disrupts sarcomeric ERK-GATA4 signal transduction and abrogates phenylephrine-induced cardiomyocyte hypertrophy
Lin Zhong, Manuel Chiusa, Adrian G. Cadar, Angel Lin, Susan Samaras, Jeffrey M. Davidson, Chee C. Lim
Cardiovasc Res. 2015 May 1; 106(2): 261–271. Published online 2015 Mar 13. doi: 10.1093/cvr/cvv108
PMCID:
PMC4481572
AbstractArticlePDF–1.0M
19.
Global Deletion of Ankrd1 Results in a Wound-Healing Phenotype Associated with Dermal Fibroblast Dysfunction
Susan E. Samaras, Karinna Almodóvar-García, Nanjun Wu, Fang Yu, Jeffrey M. Davidson
Am J Pathol. 2015 Jan; 185(1): 96–109. doi: 10.1016/j.ajpath.2014.09.018
PMCID:
PMC4278243
AbstractArticlePDF–2.2M
20.
Cytosolic CARP Promotes Angiotensin II- or Pressure Overload-Induced Cardiomyocyte Hypertrophy through Calcineurin Accumulation
Ci Chen, Liang Shen, Shiping Cao, Xixian Li, Wanling Xuan, Jingwen Zhang, Xiaobo Huang, Jianping Bin, Dingli Xu, Guofeng Li, Masafumi Kitakaze, Yulin Liao
PLoS One. 2014; 9(8): e104040. Published online 2014 Aug 4. doi: 10.1371/journal.pone.0104040
PMCID:
PMC4121294
AbstractArticlePDF–5.7M

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