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Select item 107194801.

Free heme and hemopexin in acute kidney injury after cardiopulmonary bypass and transient renal ischemia

Robert Greite, Sebastian Schott, Li Wang, Lukas Gohlke, Kirill Kreimann, Katja Derlin, Marcel Gutberlet, Martina Schmidbauer, Andreas Leffler, Igor Tudorache, Jawad Salman, Fabio Ius, Ruslan Natanov, Christine Fegbeutel, Axel Haverich, Ralf Lichtinghagen, Anne M. Hüsing, Sibylle von Vietinghoff, Roland Schmitt, Nelli Shushakova, Song Rong, Hermann Haller, Kai M. Schmidt‐Ott, Magnus Gram, Vijith Vijayan, Irina Scheffner, Wilfried Gwinner, Stephan Immenschuh

Clin Transl Sci. 2023 Dec; 16(12): 2729–2743. Published online 2023 Oct 30. doi: 10.1111/cts.13667

PMCID:: PMC10719480

Abstract Article PDF–40M

Select item 102775642.

Free heme exacerbates colonic injury induced by anti-cancer therapy

Philippa Seika, Monika Janikova, Sahana Asokan, Lubica Janovicova, Eva Csizmadia, Mckenzie O’Connell, Simon C. Robson, Jonathan Glickman, Barbara Wegiel

Front Immunol. 2023; 14: 1184105. Published online 2023 Jun 5. doi: 10.3389/fimmu.2023.1184105

PMCID:: PMC10277564

Abstract Article PDF–28M

Select item 97887803.

Circulating hemopexin modulates anthracycline cardiac toxicity in patients and in mice

Jing Liu, Sarah Lane, Rahul Lall, Michele Russo, Laurie Farrell, Melis Debreli Coskun, Casie Curtin, Raquel Araujo-Gutierrez, Marielle Scherrer-Crosbie, Barry H. Trachtenberg, Jonghan Kim, Emanuela Tolosano, Alessandra Ghigo, Robert E. Gerszten, Aarti Asnani

Sci Adv. 2022 Dec; 8(51): eadc9245. Published online 2022 Dec 23. doi: 10.1126/sciadv.adc9245

PMCID:: PMC9788780

Abstract Article PDF–3.3M

Select item 87180904.

Skeletal muscle atrophy‐induced hemopexin accelerates onset of cognitive impairment in Alzheimer's disease

Tsukasa Nagase, Chihiro Tohda

J Cachexia Sarcopenia Muscle. 2021 Dec; 12(6): 2199–2210. Published online 2021 Oct 17. doi: 10.1002/jcsm.12830

PMCID:: PMC8718090

Abstract Article PDF–10M

Select item 81964225.

Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity

Rodrigo W. Alves de Souza, David Gallo, Ghee Rye Lee, Eri Katsuyama, Alexa Schaufler, Janick Weber, Eva Csizmadia, George C. Tsokos, Lauren G. Koch, Steven L. Britton, Ulrik Wisløff, Patricia C. Brum, Leo E. Otterbein

Cell Rep. Author manuscript; available in PMC 2021 Jun 12.

Published in final edited form as: Cell Rep. 2021 Apr 20; 35(3): 109018. doi: 10.1016/j.celrep.2021.109018

PMCID:: PMC8196422

Abstract Article PDF–2.8M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 75514047.

Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases

Giacomo Canesin, Annalisa Di Ruscio, Mailin Li, Simone Ummarino, Andreas Hedblom, Reeham Choudhury, Agnieszka Krzyzanowska, Eva Csizmadia, Macarena Palominos, Anna Stiehm, Alexander Ebralidze, Shao-Yong Chen, Mahmoud A. Bassal, Ping Zhao, Emanuela Tolosano, Laurence Hurley, Anders Bjartell, Daniel G. Tenen, Barbara Wegiel

Cell Rep. Author manuscript; available in PMC 2020 Oct 13.

Published in final edited form as: Cell Rep. 2020 Sep 22; 32(12): 108181. doi: 10.1016/j.celrep.2020.108181

PMCID:: PMC7551404

Abstract Article PDF–2.5M

Select item 72187358.

Hemopexin deficiency promotes acute kidney injury in sickle cell disease

Solomon F. Ofori-Acquah, Rimi Hazra, Oluwaseun O. Orikogbo, Danielle Crosby, Bethany Flage, Ezekiel B. Ackah, Diane Lenhart, Roderick J. Tan, Dario A. Vitturi, Vivian Paintsil, Ellis Owusu-Dabo, Samit Ghosh, in collaboration with the SickleGenAfrica Network

Blood. 2020 Mar 26; 135(13): 1044–1048. Prepublished online 2020 Feb 10. doi: 10.1182/blood.2019002653

PMCID:: PMC7218735

Abstract Article

Select item 58338479.

Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state

Dunxin Han, Zhongwang Yu, Weili Liu, Dou Yin, Yingyan Pu, Jifeng Feng, Yimin Yuan, Aijun Huang, Li Cao, Cheng He

Cell Death Dis. 2018 Feb; 9(2): 181. Published online 2018 Feb 7. doi: 10.1038/s41419-017-0236-8

PMCID:: PMC5833847

Abstract Article PDF–3.0M

Select item 583379610.

Hemopexin is required for adult neurogenesis in the subventricular zone/olfactory bulb pathway

Yanling Zhu, Yang Qiu, Mengjia Chen, Yi Zhang, Li Cao, Zhida Su, Yimin Yuan, Aijun Huang, Yinyan Pu, Cheng He

Cell Death Dis. 2018 Mar; 9(3): 268. Published online 2018 Feb 15. doi: 10.1038/s41419-018-0328-0

PMCID:: PMC5833796

Abstract Article PDF–6.8M

Select item 534594111.

IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections

Kei Sakamoto, Yun-Gi Kim, Hideki Hara, Nobuhiko Kamada, Gustavo Caballero-Flores, Emanuela Tolosano, Miguel P. Soares, José L. Puente, Naohiro Inohara, Gabriel Núñez

Sci Immunol. Author manuscript; available in PMC 2017 Mar 10.

Published in final edited form as: Sci Immunol. 2017 Feb; 2(8): eaai8371. Published online 2017 Feb 3. doi: 10.1126/sciimmunol.aai8371

PMCID:: PMC5345941

Abstract Article PDF–1.2M

Select item 488225712.

ApoE^−/− Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function

Niyati U. Mehta, Victor Grijalva, Susan Hama, Alan Wagner, Mohamad Navab, Alan M. Fogelman, Srinivasa T. Reddy

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Jun; 36(6): 1152–1163. Published online 2016 Apr 14. doi: 10.1161/ATVBAHA.115.306991

PMCID:: PMC4882257

Abstract Article PDF–1.3M

Select item 473663813.

Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage

Bo Ma, Jason Patrick Day, Harrison Phillips, Bryan Slootsky, Emanuela Tolosano, Sylvain Doré

J Neuroinflammation. 2016; 13: 26. Published online 2016 Feb 1. doi: 10.1186/s12974-016-0490-1

PMCID:: PMC4736638

Abstract Article PDF–2.1M

Select item 468738814.

Dysregulation of the haem-haemopexin axis is associated with severe malaria in a case–control study of Ugandan children

Robyn E. Elphinstone, Frank Riley, Tian Lin, Sarah Higgins, Aggrey Dhabangi, Charles Musoke, Christine Cserti-Gazdewich, Raymond F. Regan, H. Shaw Warren, Kevin C. Kain

Malar J. 2015; 14: 511. Published online 2015 Dec 21. doi: 10.1186/s12936-015-1028-1

PMCID:: PMC4687388

Abstract Article PDF–1.0M

Select item 449612615.

Haemopexin affects iron distribution and ferritin expression in mouse brain

Noemi Morello, Elisabetta Tonoli, Federica Logrand, Veronica Fiorito, Sharmila Fagoonee, Emilia Turco, Lorenzo Silengo, Alessandro Vercelli, Fiorella Altruda, Emanuela Tolosano

J Cell Mol Med. 2009 Oct; 13(10): 4192–4204. Published online 2008 Dec 16. doi: 10.1111/j.1582-4934.2008.00611.x

PMCID:: PMC4496126

Abstract Article PDF–1.5M

Select item 442482416.

Hemopexin in severe inflammation and infection: mouse models and human diseases

Tian Lin, Dayana Maita, Sujatha R Thundivalappil, Frank E Riley, Jasmin Hambsch, Linda J Van Marter, Helen A Christou, Lorenzo Berra, Shawn Fagan, David C Christiani, H Shaw Warren

Crit Care. 2015; 19(1): 166. Published online 2015 Apr 15. doi: 10.1186/s13054-015-0885-x