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Items: 1 to 20 of 52

1.
Functional modulation of phosphodiesterase-6 by calcium in mouse rod photoreceptors
Teemu Turunen, Ari Koskelainen
Sci Rep. 2021; 11: 8938. Published online 2021 Apr 26. doi: 10.1038/s41598-021-88140-8
PMCID:
PMC8076185
AbstractArticlePDF–2.7M
2.
Retinal degeneration-3 protein promotes photoreceptor survival by suppressing activation of guanylyl cyclase rather than accelerating GMP recycling
Alexander M. Dizhoor, Elena V. Olshevskaya, Igor V. Peshenko
J Biol Chem. 2021 Jan-Jun; 296: 100362. Published online 2021 Feb 2. doi: 10.1016/j.jbc.2021.100362
PMCID:
PMC8047982
AbstractArticlePDF–2.2M
3.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
4.
GCAP neuronal calcium sensor proteins mediate photoreceptor cell death in the rd3 mouse model of LCA12 congenital blindness by involving endoplasmic reticulum stress
Anna Plana-Bonamaisó, Santiago López-Begines, Jordi Andilla, María José Fidalgo, Pablo Loza-Alvarez, Josep María Estanyol, Pedro de la Villa, Ana Méndez
Cell Death Dis. 2020 Jan; 11(1): 62. Published online 2020 Jan 24. doi: 10.1038/s41419-020-2255-0
PMCID:
PMC6981271
AbstractArticlePDF–6.7M
5.
Characterization of zygotic genome activation-dependent maternal mRNA clearance in mouse
Qian-Qian Sha, Ye-Zhang Zhu, Sen Li, Yu Jiang, Lu Chen, Xiao-Hong Sun, Li Shen, Xiang-Hong Ou, Heng-Yu Fan
Nucleic Acids Res. 2020 Jan 24; 48(2): 879–894. Published online 2019 Nov 28. doi: 10.1093/nar/gkz1111
PMCID:
PMC6954448
AbstractArticlePDF–5.5M
6.
Retinal guanylyl cyclase activation by calcium sensor proteins mediates photoreceptor degeneration in an rd3 mouse model of congenital human blindness
Alexander M. Dizhoor, Elena V. Olshevskaya, Igor V. Peshenko
J Biol Chem. 2019 Sep 13; 294(37): 13729–13739. Published online 2019 Jul 25. doi: 10.1074/jbc.RA119.009948
PMCID:
PMC6746453
AbstractArticlePDF–2.6M
7.
The Y99C Mutation in Guanylyl Cyclase-Activating Protein 1 Increases Intracellular Ca2+ and Causes Photoreceptor Degeneration in Transgenic Mice
Elena V. Olshevskaya, Peter D. Calvert, Michael L. Woodruff, Igor V. Peshenko, Andrey B. Savchenko, Clint L. Makino, Ye-Shih Ho, Gordon L. Fain, Alexander M. Dizhoor
J Neurosci. 2004 Jul 7; 24(27): 6078–6085. doi: 10.1523/JNEUROSCI.0963-04.2004
PMCID:
PMC6729660
AbstractArticlePDF–586K
8.
Determination of basal phosphodiesterase activity in mouse rod photoreceptors with cGMP clamp
Teemu T. Turunen, Ari Koskelainen
Sci Rep. 2019; 9: 1183. Published online 2019 Feb 4. doi: 10.1038/s41598-018-37661-w
PMCID:
PMC6362171
AbstractArticlePDF–2.8M
9.
Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State
Shinya Sato, Beata Jastrzebska, Andreas Engel, Krzysztof Palczewski, Vladimir J. Kefalov
J Neurosci. 2019 Jan 9; 39(2): 212–223. doi: 10.1523/JNEUROSCI.1980-18.2018
PMCID:
PMC6325258
AbstractArticlePDF–1.2M
10.
Investigating the Ca2+-dependent and Ca2+-independent mechanisms for mammalian cone light adaptation
Frans Vinberg, Vladimir J. Kefalov
Sci Rep. 2018; 8: 15864. Published online 2018 Oct 26. doi: 10.1038/s41598-018-34073-8
PMCID:
PMC6203770
AbstractArticlePDF–2.6M
11.
Guanylate cyclase–activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors
Frans Vinberg, Igor V. Peshenko, Jeannie Chen, Alexander M. Dizhoor, Vladimir J. Kefalov
J Biol Chem. 2018 May 11; 293(19): 7457–7465. Published online 2018 Mar 16. doi: 10.1074/jbc.RA117.001574
PMCID:
PMC5949989
AbstractArticlePDF–1.1M
12.
GUCY2D Cone–Rod Dystrophy-6 Is a “Phototransduction Disease” Triggered by Abnormal Calcium Feedback on Retinal Membrane Guanylyl Cyclase 1
Shinya Sato, Igor V. Peshenko, Elena V. Olshevskaya, Vladimir J. Kefalov, Alexander M. Dizhoor
J Neurosci. 2018 Mar 21; 38(12): 2990–3000. doi: 10.1523/JNEUROSCI.2985-17.2018
PMCID:
PMC5864148
AbstractArticlePDF–2.8M
13.
Molecular determinants of Guanylate Cyclase Activating Protein subcellular distribution in photoreceptor cells of the retina
Santiago López-Begines, Anna Plana-Bonamaisó, Ana Méndez
Sci Rep. 2018; 8: 2903. Published online 2018 Feb 13. doi: 10.1038/s41598-018-20893-1
PMCID:
PMC5811540
AbstractArticlePDF–3.3M
14.
Spontaneous activation of visual pigments in relation to openness/closedness of chromophore-binding pocket
Wendy Wing Sze Yue, Rikard Frederiksen, Xiaozhi Ren, Dong-Gen Luo, Takahiro Yamashita, Yoshinori Shichida, M Carter Cornwall, King-Wai Yau
eLife. 2017; 6: e18492. Published online 2017 Feb 10. doi: 10.7554/eLife.18492
PMCID:
PMC5302883
AbstractArticlePDF–1.8M
15.
Functional Study and Mapping Sites for Interaction with the Target Enzyme in Retinal Degeneration 3 (RD3) Protein
Igor V. Peshenko, Elena V. Olshevskaya, Alexander M. Dizhoor
J Biol Chem. 2016 Sep 9; 291(37): 19713–19723. Published online 2016 Jul 28. doi: 10.1074/jbc.M116.742288
PMCID:
PMC5016703
AbstractArticlePDF–2.9M
16.
Bicarbonate and Ca2+ Sensing Modulators Activate Photoreceptor ROS-GC1 Synergistically
Teresa Duda, Alexandre Pertzev, Clint L. Makino, Rameshwar K. Sharma
Front Mol Neurosci. 2016; 9: 5. Published online 2016 Jan 28. doi: 10.3389/fnmol.2016.00005
PMCID:
PMC4729890
AbstractArticlePDF–1.1M
17.
A novel Ca2+-feedback mechanism extends the operating range of mammalian rods to brighter light
Frans Vinberg, Teemu T. Turunen, Hanna Heikkinen, Marja Pitkänen, Ari Koskelainen
J Gen Physiol. 2015 Oct; 146(4): 307–321. doi: 10.1085/jgp.201511412
PMCID:
PMC4586592
AbstractArticlePDF–1.9M
18.
Regulation of Mammalian Cone Phototransduction by Recoverin and Rhodopsin Kinase
Keisuke Sakurai, Jeannie Chen, Shahrokh C. Khani, Vladimir J. Kefalov
J Biol Chem. 2015 Apr 3; 290(14): 9239–9250. Published online 2015 Feb 11. doi: 10.1074/jbc.M115.639591
PMCID:
PMC4423708
AbstractArticlePDF–2.5M
19.
Evaluating the Role of Retinal Membrane Guanylyl Cyclase 1 (RetGC1) Domains in Binding Guanylyl Cyclase-activating Proteins (GCAPs)
Igor V. Peshenko, Elena V. Olshevskaya, Alexander M. Dizhoor
J Biol Chem. 2015 Mar 13; 290(11): 6913–6924. Published online 2015 Jan 23. doi: 10.1074/jbc.M114.629642
PMCID:
PMC4358116
AbstractArticlePDF–2.7M
20.
Impaired Association of Retinal Degeneration-3 with Guanylate Cyclase-1 and Guanylate Cyclase-activating Protein-1 Leads to Leber Congenital Amaurosis-1
Rahel Zulliger, Muna I. Naash, Raju V. S. Rajala, Robert S. Molday, Seifollah Azadi
J Biol Chem. 2015 Feb 6; 290(6): 3488–3499. Published online 2014 Dec 4. doi: 10.1074/jbc.M114.616656
PMCID:
PMC4319016
AbstractArticlePDF–3.5M

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