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Select item 111594061.

Silencing of SOCS1 in macrophages suppresses tumor development by enhancing antitumor inflammation

Masayuki Hashimoto, Toranoshin Ayada, Ichiko Kinjyo, Kiyokazu Hiwatashi, Hideyuki Yoshida, Yasunori Okada, Takashi Kobayashi, Akihiko Yoshimura

Cancer Sci. 2009 Apr; 100(4): 730–736. Published online 2009 Feb 17. doi: 10.1111/j.1349-7006.2009.01098.x

PMCID:: PMC11159406

Abstract Article PDF–1.8M

Select item 111588482.

Enhancement of antiproliferative activity of interferons by RNA interference‐mediated silencing of SOCS gene expression in tumor cells

Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshinobu Takakura

Cancer Sci. 2008 Aug; 99(8): 1650–1655. Published online 2008 Aug 14. doi: 10.1111/j.1349-7006.2008.00850.x

Correction in:: Cancer Sci. 2008 Oct; 99(10): 2106.

PMCID:: PMC11158848

Abstract Article PDF–263K

Select item 111158543.

Suppressor of cytokine signaling-1 inhibits caspase activation and protects from cytokine-induced beta cell death

Irina I. Zaitseva, Monica Hultcrantz, Vladimir Sharoyko, Malin Flodström-Tullberg, Sergei V. Zaitsev, Per-Olof Berggren

Cell Mol Life Sci. 2009 Dec; 66(23): 3787–3795. Published online 2009 Sep 10. doi: 10.1007/s00018-009-0151-y

PMCID:: PMC11115854

Abstract Article PDF–376K

Select item 109506984.

IL-13 facilitates ferroptotic death in asthmatic epithelial cells via SOCS1-mediated ubiquitinated degradation of SLC7A11

Manli Miao, Min Pan, Xu Chen, Jiapan Shen, Ling Zhang, Xiaoxia Feng, Mengting Chen, Guofeng Cui, Huaiyuan Zong, Wen Zhang, Shuang Chang, Fangzhou Xu, Zixi Wang, Dapeng Li, Weiwei Liu, Zhao Ding, Shengquan Zhang, Biao Chen, Xiaojun Zha, Xiaoyun Fan

Redox Biol. 2024 May; 71: 103100. Published online 2024 Mar 8. doi: 10.1016/j.redox.2024.103100

PMCID:: PMC10950698

Abstract Article PDF–25M

Select item 109176605.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109122706.

Downregulation of lncRNA CDKN2B-AS1 attenuates inflammatory response in mice with allergic rhinitis by regulating miR-98-5p/SOCS1 axis

Bangyu Deng, Yunxia zhao, Jisheng Liu

Funct Integr Genomics. 2024; 24(2): 48. Published online 2024 Mar 4. doi: 10.1007/s10142-024-01318-x

PMCID:: PMC10912270

Abstract Article PDF–4.0M

Select item 106930167.

MicroRNA-155 targets SOCS1 to inhibit osteoclast differentiation during orthodontic tooth movement

Yao Jiao, Sicong Mi, Xiaoyan Li, Yitong Liu, Nannan Han, Junji Xu, Yi Liu, Song Li, Lijia Guo

BMC Oral Health. 2023; 23: 955. Published online 2023 Dec 1. doi: 10.1186/s12903-023-03443-8

PMCID:: PMC10693016

Abstract Article PDF–11M

Select item 105827468.

Hepatic stellate cell-intrinsic role of SOCS1 in controlling hepatic fibrogenic response and the pro-inflammatory macrophage compartment during liver fibrosis

Rajani Kandhi, Mehdi Yeganeh, Akihiko Yoshimura, Alfredo Menendez, Sheela Ramanathan, Subburaj Ilangumaran

Front Immunol. 2023; 14: 1259246. Published online 2023 Oct 4. doi: 10.3389/fimmu.2023.1259246

PMCID:: PMC10582746

Abstract Article PDF–11M

Select item 104337139.

Low‑dose ionizing radiation attenuates high glucose‑induced hepatic apoptosis and immune factor release via modulation of a miR‑155‑SOCS1 axis

Hongqiong Fan, Shanshan Liu, Benzheng Jiao, Xinyue Liang

Mol Med Rep. 2023 Sep; 28(3): 171. Published online 2023 Jul 24. doi: 10.3892/mmr.2023.13058

PMCID:: PMC10433713

Abstract Article PDF–934K

Select item 1006976210.

Microtubule-dependent mechanism of anti-inflammatory effect of SOCS1 in endothelial dysfunction and lung injury

Pratap Karki, Boyoung Cha, Chen-Ou Zhang, Yue Li, Yunbo Ke, Kamoltip Promnares, Kozo Kaibuchi, Akihiko Yoshimura, Konstantin G. Birukov, Anna A. Birukova

FASEB J. Author manuscript; available in PMC 2023 Apr 3.

Published in final edited form as: FASEB J. 2021 Apr; 35(4): e21388. doi: 10.1096/fj.202001477RR

PMCID:: PMC10069762

Abstract Article PDF–3.0M

Select item 991361211.

SOCS1 Deficiency Promotes Hepatocellular Carcinoma via SOCS3-Dependent CDKN1A Induction and NRF2 Activation

Md Gulam Musawwir Khan, Nadia Boufaied, Mehdi Yeganeh, Rajani Kandhi, Stephanie Petkiewicz, Ankur Sharma, Akihiko Yoshimura, Gerardo Ferbeyre, David P. Labbé, Sheela Ramanathan, Subburaj Ilangumaran

Cancers (Basel) 2023 Feb; 15(3): 905. Published online 2023 Jan 31. doi: 10.3390/cancers15030905

PMCID:: PMC9913612

Abstract Article PDF–2.6M

Select item 926812912.

LncRNA MALAT1 Participates in Protection of High-Molecular-Weight Hyaluronan against Smoke-Induced Acute Lung Injury by Upregulation of SOCS-1

Shaoguang Li, Bin Li, Ke Lang, Yubei Gong, Xiang Cheng, Shufen Deng, Qiwen Shi, Hang Zhao

Molecules. 2022 Jul; 27(13): 4128. Published online 2022 Jun 27. doi: 10.3390/molecules27134128

PMCID:: PMC9268129

Abstract Article PDF–1.2M

Select item 901455913.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 901203414.

Effects of SOCS1-overexpressing dendritic cells on Th17- and Treg-related cytokines in COPD mice

Shi-xia Liao, Jie Chen, Lan-Ying Zhang, Jing Zhang, Peng-Peng Sun, Yao Ou-Yang

BMC Pulm Med. 2022; 22: 145. Published online 2022 Apr 15. doi: 10.1186/s12890-022-01931-1

PMCID:: PMC9012034

Abstract Article PDF–3.8M

Select item 880696315.

Solid lipid nanoparticle delivery of rhynchophylline enhanced the efficiency of allergic asthma treatment via the upregulation of suppressor of cytokine signaling 1 by repressing the p38 signaling pathway

Chuanfeng Lv, Hui Li, Hongxia Cui, Qianyu Bi, Meng Wang

Bioengineered. 2021; 12(1): 8635–8649. Published online 2021 Oct 21. doi: 10.1080/21655979.2021.1988364

PMCID:: PMC8806963

Abstract Article PDF–2.6M

Select item 811920516.

miR-122 promotes virus-induced lung disease by targeting SOCS1

Adam M. Collison, Leon A. Sokulsky, Elizabeth Kepreotes, Ana Pereira de Siqueira, Matthew Morten, Michael R. Edwards, Ross P. Walton, Nathan W. Bartlett, Ming Yang, Thi Hiep Nguyen, Sebastian L. Johnston, Paul S. Foster, Joerg Mattes

JCI Insight. 2021 Apr 8; 6(7): e127933. Published online 2021 Apr 8. doi: 10.1172/jci.insight.127933

PMCID:: PMC8119205

Abstract Article PDF–3.2M

Select item 797373217.

Suppressor of cytokine signaling-1 mimetic peptides attenuate lymphocyte activation in the MRL/lpr mouse autoimmune model

Jatin Sharma, Teresa D. Collins, Tracoyia Roach, Shiwangi Mishra, Brandon K. Lam, Zaynab Sidi Mohamed, Antia E. Veal, Timothy B. Polk, Amari Jones, Caleb Cornaby, Mohammed I. Haider, Leilani Zeumer-Spataro, Howard M. Johnson, Laurence M. Morel, Joseph Larkin, III

Sci Rep. 2021; 11: 6354. Published online 2021 Mar 18. doi: 10.1038/s41598-021-86017-4

PMCID:: PMC7973732

Abstract Article PDF–4.3M

Select item 775574118.

N⁶-Adenosine methylation of Socs1 mRNA is required to sustain the negative feedback control of macrophage activation

Jie Du, Wang Liao, Weicheng Liu, Dilip K. Deb, Lei He, Phillip J. Hsu, Tivoli Nguyen, Linda Zhang, Marc Bissonnette, Chuan He, Yan Chun Li

Dev Cell. Author manuscript; available in PMC 2021 Dec 21.

Published in final edited form as: Dev Cell. 2020 Dec 21; 55(6): 737–753.e7. Published online 2020 Nov 20. doi: 10.1016/j.devcel.2020.10.023

PMCID:: PMC7755741

Abstract Article PDF–3.2M

Select item 747802219.

Anti-inflammatory, antioxidant and renoprotective effects of SOCS1 mimetic peptide in the BTBR ob/ob mouse model of type 2 diabetes

Lucas Opazo-Ríos, Yenniffer Sanchez Matus, Raúl R Rodrigues-Díez, Daniel Carpio, Alejandra Droguett, Jesús Egido, Carmen Gomez-Guerrero, Sergio Mezzano

BMJ Open Diabetes Res Care. 2020; 8(1): e001242. Published online 2020 Sep 7. doi: 10.1136/bmjdrc-2020-001242

PMCID:: PMC7478022

Abstract Article PDF–20M

Select item 717922820.

MicroRNA-155 Participates in Smoke-Inhalation-Induced Acute Lung Injury through Inhibition of SOCS-1

Yue Zhang, Yifang Xie, Leifang Zhang, Hang Zhao

Molecules. 2020 Mar; 25(5): 1022. Published online 2020 Feb 25. doi: 10.3390/molecules25051022

PMCID:: PMC7179228

Abstract Article PDF–2.5M

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