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Items: 1 to 20 of 59

1.
Adrenal-Permissive Germline HSD3B1 Allele and Prostate Cancer Outcomes
Rana R. McKay, Tyler J. Nelson, Meghana S. Pagadala, Craig C. Teerlink, Anthony Gao, Alex K. Bryant, Fatai Y. Agiri, Kripa Guram, Reid F. Thompson, Kathryn M. Pridgen, Tyler M. Seibert, Kyung Min Lee, Hannah Carter, Julie A. Lynch, Richard L. Hauger, Brent S. Rose
JAMA Netw Open. 2024 Mar; 7(3): e242976. Published online 2024 Mar 20. doi: 10.1001/jamanetworkopen.2024.2976
PMCID:
PMC10955379
AbstractArticle
2.
Intratumoral androgen biosynthesis associated with 3β-hydroxysteroid dehydrogenase 1 promotes resistance to radiotherapy in prostate cancer
Shinjini Ganguly, Zaeem Lone, Andrew Muskara, Jarrell Imamura, Aimalie Hardaway, Mona Patel, Mike Berk, Timothy D. Smile, Elai Davicioni, Kevin L. Stephans, Jay Ciezki, Christopher J. Weight, Shilpa Gupta, Chandana A. Reddy, Rahul D. Tendulkar, Abhishek A. Chakraborty, Eric A. Klein, Nima Sharifi, Omar Y. Mian
J Clin Invest. 2023 Nov 15; 133(22): e165718. Published online 2023 Nov 15. doi: 10.1172/JCI165718
PMCID:
PMC10645386
AbstractArticlePDF–14M
3.
High carrier frequency of a nonsense p.Trp230* variant in HSD3B2 gene in Ossetians
Nina Makretskaya, Natalia Kalinchenko, Inna Tebieva, Sofya Ionova, Rena Zinchenko, Andrey Marakhonov, Anatoly Tiulpakov
Front Endocrinol (Lausanne) 2023; 14: 1146768. Published online 2023 May 16. doi: 10.3389/fendo.2023.1146768
PMCID:
PMC10236362
AbstractArticlePDF–501K
4.
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta
Alison Dickson, Eylan Yutuc, Catherine A. Thornton, James E. Dunford, Udo Oppermann, Yuqin Wang, William J. Griffiths
Open Biol. 2023 May; 13(5): 220313. Published online May 3, 2023. doi: 10.1098/rsob.220313
PMCID:
PMC10154939
AbstractArticlePDF–3.5M
5.
HSD3B1 Expression Is Upregulated by Interleukin 4 in HT-29 Colon Cancer Cells via Multiple Signaling Pathways
Hsin-Mei Chen, Pei-Yu Hung, Chih-Hung Chen, Yu-Jhen Yu, Ming-Shan Syu, Meng-Chun Hu
Int J Mol Sci. 2022 Nov; 23(21): 13572. Published online 2022 Nov 5. doi: 10.3390/ijms232113572
PMCID:
PMC9654614
AbstractArticlePDF–2.5M
6.
Association Between Adrenal-Restrictive HSD3B1 Inheritance and Hormone-Independent Subtypes of Endometrial and Breast Cancer
Jeffrey M McManus, Roberto Vargas, Peter S Bazeley, Fredrick R Schumacher, Nima Sharifi
JNCI Cancer Spectr. 2022 Oct; 6(5): pkac061. Published online 2022 Aug 10. doi: 10.1093/jncics/pkac061
PMCID:
PMC9475354
AbstractArticlePDF–458K
7.
Role of single nucleotide polymorphisms of the HSD3B1 gene (rs6203 and rs33937873) in the prediction of prostate cancer risk
Yasmine M. Amrousy, Hesham Haffez, Doaa M. Abdou, Hanaa B. Atya
Mol Med Rep. 2022 Aug; 26(2): 271. Published online 2022 Jul 4. doi: 10.3892/mmr.2022.12787
PMCID:
PMC9309536
AbstractArticlePDF–455K
8.
Inheritance of a common androgen synthesis variant allele is associated with female COVID susceptibility in UK Biobank
Jeffrey M. McManus, Navin Sabharwal, Peter Bazeley, Nima Sharifi
Eur J Endocrinol. Author manuscript; available in PMC 2023 May 12.
Published in final edited form as: Eur J Endocrinol. 2022 May 12; 187(1): 1–14. Published online 2022 May 12. doi: 10.1530/EJE-21-0996
PMCID:
PMC9106901
AbstractArticlePDF–1.3M
9.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
10.
TRIP12 Ubiquitination of Glucocerebrosidase Contributes to Neurodegeneration in Parkinson’s Disease
Bo Am Seo, Donghoon Kim, Heehong Hwang, Min Seong Kim, Shi-Xun Ma, Seung-Hwan Kwon, Sin Ho Kweon, Hu Wang, Je Min Yoo, Seulah Choi, Sang Ho Kwon, Sung-Ung Kang, Tae-In Kam, Kwangsoo Kim, Senthilkumar S Karuppagounder, Bong Gu Kang, Saebom Lee, Hyejin Park, Sangjune Kim, Wei Yan, Yong-Shi Li, Sheng-Han Kuo, Javier Redding-Ochoa, Olga Pletnikova, Juan C. Troncoso, Gabsang Lee, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Han Seok Ko
Neuron. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Neuron. 2021 Dec 1; 109(23): 3758–3774.e11. Published online 2021 Oct 12. doi: 10.1016/j.neuron.2021.09.031
PMCID:
PMC8639668
AbstractArticlePDF–2.6M
11.
Adrenal-permissive HSD3B1 genetic inheritance and risk of estrogen-driven postmenopausal breast cancer
Megan L. Kruse, Mona Patel, Jeffrey McManus, Yoon-Mi Chung, Xiuxiu Li, Wei Wei, Peter S. Bazeley, Fumihiko Nakamura, Aimalie Hardaway, Erinn Downs, Sarat Chandarlapaty, Mathew Thomas, Halle C.F. Moore, George T. Budd, W.H. Wilson Tang, Stanley L. Hazen, Aaron Bernstein, Serena Nik-Zainal, Jame Abraham, Nima Sharifi
JCI Insight. 2021 Oct 22; 6(20): e150403. Published online 2021 Oct 22. doi: 10.1172/jci.insight.150403
PMCID:
PMC8564898
AbstractArticlePDF–410K
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
Germline HSD3B1 Genetics and Prostate Cancer Outcomes
Lewis Thomas, Nima Sharifi
Urology. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: Urology. 2020 Nov; 145: 13–21. Published online 2020 Aug 28. doi: 10.1016/j.urology.2020.08.028
PMCID:
PMC7657962
AbstractArticlePDF–494K
14.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
15.
HSD3B1 Genotype and Clinical Outcomes in Metastatic Castration-Sensitive Prostate Cancer
Jason W. D. Hearn, Christopher J. Sweeney, Nima Almassi, Chad A. Reichard, Chandana A. Reddy, Hong Li, Brian Hobbs, David F. Jarrard, Yu-Hui Chen, Robert Dreicer, Jorge A. Garcia, Michael A. Carducci, Robert S. DiPaola, Nima Sharifi
JAMA Oncol. 2020 Apr; 6(4): e196496. Published online 2020 Feb 13. doi: 10.1001/jamaoncol.2019.6496
PMCID:
PMC7042830
AbstractArticle
16.
HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma
Joe Zein, Benjamin Gaston, Peter Bazeley, Mark D. DeBoer, Robert P. Igo, Jr, Eugene R. Bleecker, Deborah Meyers, Suzy Comhair, Nadzeya V. Marozkina, Calvin Cotton, Mona Patel, Mohammad Alyamani, Weiling Xu, William W. Busse, William J. Calhoun, Victor Ortega, Gregory A. Hawkins, Mario Castro, Kian Fan Chung, John V. Fahy, Anne M. Fitzpatrick, Elliot Israel, Nizar N. Jarjour, Bruce Levy, David T. Mauger, Wendy C. Moore, Patricia Noel, Stephen P. Peters, W. Gerald Teague, Sally E. Wenzel, Serpil C. Erzurum, Nima Sharifi
Proc Natl Acad Sci U S A. 2020 Jan 28; 117(4): 2187–2193. Published online 2020 Jan 13. doi: 10.1073/pnas.1918819117
PMCID:
PMC6995013
AbstractArticlePDF–902K
17.
HSD3B1 Genotypes Conferring Adrenal-Restrictive and Adrenal-Permissive Phenotypes in Prostate Cancer and Beyond
Navin Sabharwal, Nima Sharifi
Endocrinology. 2019 Sep; 160(9): 2180–2188. Published online 2019 Jul 4. doi: 10.1210/en.2019-00366
PMCID:
PMC6736215
AbstractArticle
18.
Cumulus cell pappalysin-1, luteinizing hormone/choriogonadotropin receptor, amphiregulin and hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 mRNA levels associate with oocyte developmental competence and embryo outcomes
Richard J. Kordus, Akhtar Hossain, Michael C. Corso, Hrishikesh Chakraborty, Gail F. Whitman-Elia, Holly A. LaVoie
J Assist Reprod Genet. 2019 Jul; 36(7): 1457–1469. Published online 2019 Jun 11. doi: 10.1007/s10815-019-01489-8
PMCID:
PMC6657401
AbstractArticlePDF–1.1M
19.
Association of Missense Polymorphism in HSD3B1 With Outcomes Among Men With Prostate Cancer Treated With Androgen-Deprivation Therapy or Abiraterone
Masaki Shiota, Shintaro Narita, Shusuke Akamatsu, Naohiro Fujimoto, Takayuki Sumiyoshi, Maki Fujiwara, Takeshi Uchiumi, Tomonori Habuchi, Osamu Ogawa, Masatoshi Eto
JAMA Netw Open. 2019 Feb; 2(2): e190115. Published online 2019 Feb 22. doi: 10.1001/jamanetworkopen.2019.0115
PMCID:
PMC6484618
AbstractArticle
20.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M

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