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Select item 113988661.

Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation

Jiansen Lu, Jiahuan Zhang, Huaji Jiang, Zhiqiang Hu, Yufen Zhang, Lian He, Jianwu Yang, Yingchao Xie, Dan Wu, Hongyu Li, Ke Zeng, Peng Tan, Qingyue Xiao, Zijing Song, Chenglong Pan, Xiaochun Bai, Xiao Yu

eLife. 2024; 12: RP87935. Published online 2024 Sep 13. doi: 10.7554/eLife.87935

PMCID:: PMC11398866

Abstract Article PDF–7.8M

Select item 113797112.

p65 signaling dynamics drive the developmental progression of hematopoietic stem and progenitor cells through cell cycle regulation

Clyde A. Campbell, Rodolfo Calderon, Giulia Pavani, Xiaoyi Cheng, Radwa Barakat, Elizabeth Snella, Fang Liu, Xiyu Peng, Jeffrey J. Essner, Karin S. Dorman, Maura McGrail, Paul Gadue, Deborah L. French, Raquel Espin-Palazon

Nat Commun. 2024; 15: 7787. Published online 2024 Sep 6. doi: 10.1038/s41467-024-51922-5

PMCID:: PMC11379711

Abstract Article PDF–9.7M

Select item 113527453.

Role of Inflammation and the NF-κB Signaling Pathway in Hirschsprung’s Disease

Enas Zoheer Elkrewi, Ahmad A. Al Abdulqader, Rasul Khasanov, Silke Maas-Omlor, Michael Boettcher, Lucas M. Wessel, Karl-Herbert Schäfer, María Ángeles Tapia-Laliena

Biomolecules. 2024 Aug; 14(8): 992. Published online 2024 Aug 12. doi: 10.3390/biom14080992

PMCID:: PMC11352745

Abstract Article PDF–5.4M

Select item 113216374.

Multilevel Regulation of NF‐κB Signaling by NSD2 Suppresses Kras‐Driven Pancreatic Tumorigenesis

Wenxin Feng, Ningning Niu, Ping Lu, Zhuo Chen, Hanyu Rao, Wei Zhang, Chunxiao Ma, Changwei Liu, Yue Xu, Wei‐Qiang Gao, Jing Xue, Li Li

Adv Sci (Weinh) 2024 Aug; 11(30): 2309387. Published online 2024 Jun 18. doi: 10.1002/advs.202309387

PMCID:: PMC11321637

Abstract Article PDF–7.7M

Select item 113159295.

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll

EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9

PMCID:: PMC11315929

Abstract Article PDF–3.4M

Select item 111610716.

Her2 amplification, Rel-A, and Bach1 can influence APOBEC3A expression in breast cancer cells

Madeline Dennis, Alyssa Hurley, Nicholas Bray, Cameron Cordero, Jose Ilagan, Tony M. Mertz, Steven A. Roberts

PLoS Genet. 2024 May; 20(5): e1011293. Published online 2024 May 28. doi: 10.1371/journal.pgen.1011293

PMCID:: PMC11161071

Abstract Article PDF–2.6M

Select item 111598887.

Potential biomarkers involving IKK/RelA signal in early stage non‐small cell lung cancer

Xianqing Jin, Ziming Wang, Lin Qiu, Dianliang Zhang, Zhenhua Guo, Zongwei Gao, Chun Deng, Fuling Wang, Shan Wang, Chunbao Guo

Cancer Sci. 2008 Mar; 99(3): 582–589. Published online 2008 Jan 21. doi: 10.1111/j.1349-7006.2007.00713.x

PMCID:: PMC11159888

Abstract Article PDF–254K

Select item 111154968.

Annexin A4 interacts with the NF-κB p50 subunit and modulates NF-κB transcriptional activity in a Ca²⁺-dependent manner

Young-Joo Jeon, Do-Hyung Kim, Hyeyun Jung, Sang J. Chung, Seung-Wook Chi, Sayeon Cho, Sang Chul Lee, Byoung Chul Park, Sung Goo Park, Kwang-Hee Bae

Cell Mol Life Sci. 2010 Jul; 67(13): 2271–2281. Published online 2010 Mar 18. doi: 10.1007/s00018-010-0331-9

PMCID:: PMC11115496

Abstract Article PDF–659K

Select item 111099459.

WSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination

Jie Zhang, Yuanyuan Yu, Xiuqun Zou, Yaning Du, Qiankun Liang, Mengyao Gong, Yurong He, Junqi Luo, Dandan Wu, Xiaoli Jiang, Matt Sinclair, Emad Tajkhorshid, Hong-Zhuan Chen, Zhaoyuan Hou, Yuejuan Zheng, Lin-Feng Chen, Xiao-Dong Yang

Nucleic Acids Res. 2024 May 22; 52(9): 4969–4984. Published online 2024 Mar 7. doi: 10.1093/nar/gkae161

PMCID:: PMC11109945

Abstract Article PDF–1.6M

Select item 1109907510.

MiR-1976/NCAPH/P65 axis inhibits the malignant phenotypes of lung adenocarcinoma

Peiluo Huang, Hongtao Zhao, Ruonan Sun, Chunyan Liu, Lei Wu, Yao Wang, Zhengwei Gan, Xiuzhen Yang, Juan Du

Sci Rep. 2024; 14: 11211. Published online 2024 May 16. doi: 10.1038/s41598-024-61261-6

PMCID:: PMC11099075

Abstract Article PDF–15M

Select item 1109163711.

Renal ischaemia-reperfusion injury is promoted by transcription factor NF-kB p65, which inhibits TRPC6 expression by activating miR-150

Shuangyu Li, Qiubo Ma, Zengwei Ma, Ying Shi, Xiaoyan Yu, Baohua Gu, Shanshan Sun, Chunlei Yu, Lei Pang

Clin Hemorheol Microcirc. 2024; 86(3): 369–382. Prepublished online 2023 Nov 10. Published online 2024 Apr 10. doi: 10.3233/CH-231979

PMCID:: PMC11091637

Abstract Article PDF–742K

Select item 1101168712.

A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells

Yamin Liu, Jieru Yang, Dunchu Weng, Yajun Xie

Int J Mol Sci. 2024 Apr; 25(7): 3576. Published online 2024 Mar 22. doi: 10.3390/ijms25073576

PMCID:: PMC11011687

Abstract Article PDF–4.9M

Select item 1094853113.

The NF-κB RelA transcription factor is not required for CD8+ T-cell function in acute viral infection and cancer

Allison Voisin, Maud Plaschka, Marlène Perrin-Niquet, Julie Twardowski, Insaf Boutemine, Baptiste Eluard, Guilhem Lalle, Pierre Stéphan, Khaled Bouherrou, Laurie Tonon, Roxane Pommier, Anthony Ferrari, Ulf Klein, Mélanie Wencker, Véronique Baud, Philippe A. Cassier, Yenkel Grinberg-Bleyer

Front Immunol. 2024; 15: 1379777. Published online 2024 Mar 5. doi: 10.3389/fimmu.2024.1379777

PMCID:: PMC10948531

Abstract Article PDF–5.7M

Select item 1093202114.

The Prolonged Activation of the p65 Subunit of the NF-Kappa-B Nuclear Factor Sustains the Persistent Effect of Advanced Glycation End Products on Inflammatory Sensitization in Macrophages

Sayonara Ivana Santos de Assis, Leonardo Szalo Amendola, Maristela Mitiko Okamoto, Guilherme da Silva Ferreira, Rodrigo Tallada Iborra, Danielle Ribeiro Santos, Monique de Fátima Mello Santana, Kelly Gomes Santana, Maria Lucia Correa-Giannella, Denise Frediani Barbeiro, Francisco Garcia Soriano, Ubiratan Fabres Machado, Marisa Passarelli

Int J Mol Sci. 2024 Mar; 25(5): 2713. Published online 2024 Feb 27. doi: 10.3390/ijms25052713

PMCID:: PMC10932021

Abstract Article PDF–2.4M

Select item 1073061915.

Nuclear RPSA senses viral nucleic acids to promote the innate inflammatory response

Yan Jiang, Siqi Sun, Yuan Quan, Xin Wang, Yuling You, Xiao Zhang, Yue Zhang, Yin Liu, Bingjing Wang, Henan Xu, Xuetao Cao

Nat Commun. 2023; 14: 8455. Published online 2023 Dec 20. doi: 10.1038/s41467-023-43784-0

Correction in:: Nat Commun. 2024; 15: 855.

PMCID:: PMC10730619

Abstract Article PDF–2.4M

Select item 1071549516.

CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma

Xiaomeng Liu, Rong Tang, Jin Xu, Zhen Tan, Chen Liang, Qingcai Meng, Yubin Lei, Jie Hua, Yiyin Zhang, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Si Shi

Gut. 2023 Dec; 72(12): 2329–2343. Published online 2023 Aug 4. doi: 10.1136/gutjnl-2022-329349

PMCID:: PMC10715495

Abstract Article PDF–16M

Select item 1059098217.

The kinesin-14 family motor protein KIFC2 promotes prostate cancer progression by regulating p65

Xinyu Liu, Yu Lin, Weibing Long, Renzheng Yi, Xiongfeng Zhang, Chaoqun Xie, Na Jin, Ziran Qiu, Xiaobing Liu

J Biol Chem. 2023 Nov; 299(11): 105253. Published online 2023 Sep 14. doi: 10.1016/j.jbc.2023.105253

PMCID:: PMC10590982

Abstract Article PDF–5.3M

Select item 1058592418.

Paracrine activin B-NF-κB signaling shapes an inflammatory tumor microenvironment in gastric cancer via fibroblast reprogramming

Yangbing Jin, Qu Cai, Lingquan Wang, Jun Ji, Ying Sun, Jinling Jiang, Chao Wang, Junwei Wu, Benyan Zhang, Liqin Zhao, Feng Qi, Beiqin Yu, Jun Zhang

J Exp Clin Cancer Res. 2023; 42: 269. Published online 2023 Oct 19. doi: 10.1186/s13046-023-02861-4

PMCID:: PMC10585924

Abstract Article PDF–12M

Select item 1040395019.

Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease

Longyuan Zhou, Liguo Zhu, Xiaomin Wu, Shixian Hu, Shenghong Zhang, Min Ning, Jun Yu, Minhu Chen

BMC Med. 2023; 21: 287. Published online 2023 Aug 4. doi: 10.1186/s12916-023-02989-2

PMCID:: PMC10403950

Abstract Article PDF–17M

Select item 1033032520.

INKILN is a novel long noncoding RNA promoting vascular smooth muscle inflammation via scaffolding MKL1 and USP10

Wei Zhang, Jinjing Zhao, Lin Deng, Nestor Ishimwe, Jessica Pauli, Wen Wu, Shengshuai Shan, Wolfgang Kempf, Margaret D Ballantyne, David Kim, Qing Lyu, Matthew Bennett, Julie Rodor, Adam W. Turner, Yao Wei Lu, Ping Gao, Mihyun Choi, Ganesh Warthi, Ha Won Kim, Margarida M Barroso, William B. Bryant, Clint L. Miller, Neal L. Weintraub, Lars Maegdefessel, Joseph M. Miano, Andrew H Baker, Xiaochun Long

Circulation. Author manuscript; available in PMC 2024 Jul 4.

Published in final edited form as: Circulation. 2023 Jul 4; 148(1): 47–67. Published online 2023 May 18. doi: 10.1161/CIRCULATIONAHA.123.063760

PMCID:: PMC10330325

Abstract Article PDF–2.1M

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