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Items: 1 to 20 of 66

1.
The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4
Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang
Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5
PMCID:
PMC10460732
AbstractArticlePDF–5.6M
2.
DUSP6 is a memory retention feedback regulator of ERK signaling for cellular resilience of human pluripotent stem cells in response to dissociation
Dae Hoon Yoo, Young Sam Im, Ji Young Oh, Dayeon Gil, Yong-Ou Kim
Sci Rep. 2023; 13: 5683. Published online 2023 Apr 7. doi: 10.1038/s41598-023-32567-8
PMCID:
PMC10082014
AbstractArticlePDF–8.2M
3.
SKA1 promotes tumor metastasis via SAFB-mediated transcription repression of DUSP6 in clear cell renal cell carcinoma
Yan Pu, Jing Han, Mengmeng Zhang, Mengxue Liu, Gulnazar Abdusamat, Huibin Liu
Aging (Albany NY) 2022 Dec 15; 14(23): 9679–9698. Published online 2022 Dec 2. doi: 10.18632/aging.204418
PMCID:
PMC9792197
AbstractArticlePDF–2.1M
4.
MicroRNA-211 modulates the DUSP6-ERK5 signaling axis to promote BRAFV600E-driven melanoma growth in vivo and BRAF/MEK inhibitor resistance
Bongyong Lee, Anupama Sahoo, Junko Sawada, John Marchica, Sanjay Sahoo, Fabiana I. A. L. Layng, Darren Finlay, Joseph Mazar, Piyush Joshi, Masanobu Komatsu, Kristiina Vuori, Petrus R. de Jong, Animesh Ray, Ranjan J. Perera
J Invest Dermatol. Author manuscript; available in PMC 2022 Apr 12.
Published in final edited form as: J Invest Dermatol. 2021 Feb; 141(2): 385–394. Published online 2020 Sep 2. doi: 10.1016/j.jid.2020.06.038
PMCID:
PMC9004592
AbstractArticlePDF–1.8M
5.
microRNA-211-5p predicts the progression of postmenopausal osteoporosis and attenuates osteogenesis by targeting dual specific phosphatase 6
Huan Wang, Xiaoyan Shi, Zhenye Guo, Feng Zhao, Weifu He, Mingming Kang, Zhi Lv
Bioengineered. 2022; 13(3): 5709–5723. Published online 2022 Feb 21. doi: 10.1080/21655979.2021.2017626
PMCID:
PMC8973771
AbstractArticlePDF–3.3M
6.
Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
Shanshan Duan, Loredana Moro, Rui Qu, Daniele Simoneschi, Hyunwoo Cho, Shaowen Jiang, Huiyong Zhao, Qing Chang, Elisa de Stanchina, Arnaldo A. Arbini, Michele Pagano
Cell Rep. Author manuscript; available in PMC 2021 Nov 9.
Published in final edited form as: Cell Rep. 2021 Oct 19; 37(3): 109870. doi: 10.1016/j.celrep.2021.109870
PMCID:
PMC8577224
AbstractArticlePDF–1.3M
7.
Knockdown of TRIM9 attenuates irinotecan-induced intestinal mucositis in IEC-6 cells by regulating DUSP6 expression via the P38 pathway
Wenjun Zhao, Qingming Wang
Mol Med Rep. 2021 Dec; 24(6): 867. Published online 2021 Oct 20. doi: 10.3892/mmr.2021.12507
PMCID:
PMC8554382
AbstractArticlePDF–4.6M
8.
DUSP6 expression is associated with osteoporosis through the regulation of osteoclast differentiation via ERK2/Smad2 signaling
Boya Zhang, Putao Yuan, Guang Xu, Zhijun Chen, Zhifei Li, Huali Ye, Jiying Wang, Peihua Shi, Xuewu Sun
Cell Death Dis. 2021 Sep; 12(9): 825. Published online 2021 Sep 2. doi: 10.1038/s41419-021-04110-y
PMCID:
PMC8413376
AbstractArticlePDF–12M
9.
Single nucleotide polymorphisms in the dual specificity phosphatase genes and risk of necrotizing enterocolitis in premature infant
M.M. Talavera, Y. Jin, E.J. Zmuda, J. Frick, Y. Liu, K.L. McBride, L.D. Nelin, J.K. Trittmann
J Neonatal Perinatal Med. Author manuscript; available in PMC 2021 Aug 27.
Published in final edited form as: J Neonatal Perinatal Med. 2020; 13(3): 373–380. doi: 10.3233/NPM-190302
PMCID:
PMC8394167
AbstractArticlePDF–369K
10.
Tripartite motif protein 11 (TRIM11), an oncogene for human lung cancer via the DUSP6-mediated ERK1/2 signaling pathway
Xiao-Lin Wang, Shi-Chun Lu, Chao Sun, Wei-Guo Jin, Yi-Wei Fan, Yu-Sheng Shu, Hong-Can Shi, Ling-Feng Min
Cancer Biol Ther. 2021; 22(4): 324–332. Published online 2021 May 10. doi: 10.1080/15384047.2021.1902912
PMCID:
PMC8183509
AbstractArticlePDF–3.1M
11.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
12.
Dual‐specificity phosphatase 6 plays a critical role in the maintenance of a cancer stem‐like cell phenotype in human endometrial cancer
Masaya Kato, Ichiro Onoyama, Sachiko Yoshida, Lin Cui, Keiko Kawamura, Keisuke Kodama, Emiko Hori, Yumiko Matsumura, Hiroshi Yagi, Kazuo Asanoma, Hideaki Yahata, Atsuo Itakura, Satoru Takeda, Kiyoko Kato
Int J Cancer. 2020 Oct 1; 147(7): 1987–1999. Published online 2020 Mar 26. doi: 10.1002/ijc.32965
PMCID:
PMC7496376
AbstractArticlePDF–2.6M
13.
Enhanced MAPK1 Function Causes a Neurodevelopmental Disorder within the RASopathy Clinical Spectrum
Marialetizia Motta, Luca Pannone, Francesca Pantaleoni, Gianfranco Bocchinfuso, Francesca Clementina Radio, Serena Cecchetti, Andrea Ciolfi, Martina Di Rocco, Mariet W. Elting, Eva H. Brilstra, Stefania Boni, Laura Mazzanti, Federica Tamburrino, Larry Walsh, Katelyn Payne, Alberto Fernández-Jaén, Mythily Ganapathi, Wendy K. Chung, Dorothy K. Grange, Ashita Dave-Wala, Shalini C. Reshmi, Dennis W. Bartholomew, Danielle Mouhlas, Giovanna Carpentieri, Alessandro Bruselles, Simone Pizzi, Emanuele Bellacchio, Francesca Piceci-Sparascio, Christina Lißewski, Julia Brinkmann, Ronald R. Waclaw, Quinten Waisfisz, Koen van Gassen, Ingrid M. Wentzensen, Michelle M. Morrow, Sara Álvarez, Mónica Martínez-García, Alessandro De Luca, Luigi Memo, Giuseppe Zampino, Cesare Rossi, Marco Seri, Bruce D. Gelb, Martin Zenker, Bruno Dallapiccola, Lorenzo Stella, Carlos E. Prada, Simone Martinelli, Elisabetta Flex, Marco Tartaglia
Am J Hum Genet. 2020 Sep 3; 107(3): 499–513. Published online 2020 Jul 27. doi: 10.1016/j.ajhg.2020.06.018
PMCID:
PMC7477014
AbstractArticlePDF–3.6M
14.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
15.
Dual-specificity phosphatase (DUSP6) in human glioblastoma: epithelial-to-mesenchymal transition (EMT) involvement
Candida Zuchegna, Erika Di Zazzo, Bruno Moncharmont, Samantha Messina
BMC Res Notes. 2020; 13: 374. Published online 2020 Aug 8. doi: 10.1186/s13104-020-05214-y
PMCID:
PMC7414695
AbstractArticlePDF–1.7M
16.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
19.
Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway
Zhaofeng Wang, Xiaobo Xu, Wenxiao Tang, Youcai Zhu, Jichao Hu, Xingen Zhang
Biomed Res Int. 2019; 2019: 9612125. Published online 2019 Dec 25. doi: 10.1155/2019/9612125
PMCID:
PMC6948331
AbstractArticlePDF–2.3M
20.
Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer
Fan Wu, Robert D. McCuaig, Christopher R. Sutton, Abel H. Y. Tan, Yoshni Jeelall, Elaine G. Bean, Jin Dai, Thiru Prasanna, Jacob Batham, Laeeq Malik, Desmond Yip, Jane E. Dahlstrom, Sudha Rao
Int J Mol Sci. 2019 Jun; 20(12): 3080. Published online 2019 Jun 24. doi: 10.3390/ijms20123080
PMCID:
PMC6627630
AbstractArticlePDF–2.7M

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