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Items: 1 to 20 of 39

1.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2
Lei Yu, Si Gui, Yawei Liu, Xiaoyu Qiu, Guozhong Zhang, Xi’an Zhang, Jun Pan, Jun Fan, Songtao Qi, Binghui Qiu
Aging (Albany NY) 2019 Aug 15; 11(15): 5300–5318. Published online 2019 Aug 5. doi: 10.18632/aging.102092
PMCID:
PMC6710058
AbstractArticlePDF–3.5M
4.
Cellular energy stress induces AMPK-mediated regulation of glioblastoma cell proliferation by PIKE-A phosphorylation
Shuai Zhang, Hao Sheng, Xiaoya Zhang, Qi Qi, Chi Bun Chan, Leilei Li, Changliang Shan, Keqiang Ye
Cell Death Dis. 2019 Mar; 10(3): 222. Published online 2019 Mar 4. doi: 10.1038/s41419-019-1452-1
PMCID:
PMC6399291
AbstractArticlePDF–1.3M
5.
SP1 and RARα regulate AGAP2 expression in cancer
Yegor Doush, Arif A. Surani, Amaia Navarro-Corcuera, Stephanie McArdle, E. Ellen Billett, Cristina Montiel-Duarte
Sci Rep. 2019; 9: 390. Published online 2019 Jan 23. doi: 10.1038/s41598-018-36888-x
PMCID:
PMC6344547
AbstractArticlePDF–3.2M
6.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
7.
Co-amplification of Phosphoinositide 3-kinase enhancer A and Cyclin-dependent kinase 4 Triggers Glioblastoma Progression
Qi Qi, Seong-Su Kang, Shuai Zhang, Cau Pham, Haian Fu, Daniel J. Brat, Keqiang Ye
Oncogene. Author manuscript; available in PMC 2017 Oct 3.
Published in final edited form as: Oncogene. 2017 Aug 10; 36(32): 4562–4572. Published online 2017 Apr 3. doi: 10.1038/onc.2017.67
PMCID:
PMC5552418
AbstractArticlePDF–2.2M
8.
α-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation
Seong Su Kang, Zhentao Zhang, Xia Liu, Fredric P. Manfredsson, Li He, P. Michael Iuvone, Xuebing Cao, Yi E. Sun, Lingjing Jin, Keqiang Ye
Proc Natl Acad Sci U S A. 2017 Jan 31; 114(5): 1183–1188. Published online 2017 Jan 17. doi: 10.1073/pnas.1618627114
PMCID:
PMC5293033
AbstractArticlePDF–1.2M
9.
Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity
S Zhang, Q Qi, C B Chan, W Zhou, J Chen, H R Luo, C Appin, D J Brat, K Ye
Cell Death Differ. 2016 Jan; 23(1): 52–63. Published online 2015 May 22. doi: 10.1038/cdd.2015.66
PMCID:
PMC4815978
AbstractArticlePDF–2.0M
10.
Reduced expression of E-cadherin and p120-catenin and elevated expression of PLC-γ1 and PIKE are associated with aggressiveness of oral squamous cell carcinoma
Yi Jiang, Liyan Liao, Chandrama Shrestha, Shangli Ji, Ying Chen, Jian Peng, Larry Wang, Eryuan Liao, Zhongjian Xie
Int J Clin Exp Pathol. 2015; 8(8): 9042–9051. Published online 2015 Aug 1.
PMCID:
PMC4583878
AbstractArticlePDF–1.0M
11.
Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in Fragile X syndrome
Christina Gross, Chia-Wei Chang, Seth M. Kelly, Aditi Bhattacharya, Sean M.J. McBride, Scott W. Danielson, Michael Q. Jiang, Chi Bun Chan, Keqiang Ye, Jay R. Gibson, Eric Klann, Thomas A. Jongens, Kenneth H. Moberg, Kimberly M. Huber, Gary J. Bassell
Cell Rep. Author manuscript; available in PMC 2016 May 5.
Published in final edited form as: Cell Rep. 2015 May 5; 11(5): 727–736. Published online 2015 Apr 23. doi: 10.1016/j.celrep.2015.03.060
PMCID:
PMC4418204
AbstractArticlePDF–2.2M
12.
The Arf GAP AGAP2 interacts with β-arrestin2 and regulates β2-adrenergic receptor recycling and ERK activation
Yuanjun Wu, Yu Zhao, Xiaojie Ma, Yunjuan Zhu, Jaimin Patel, Zhongzhen Nie
Biochem J. Author manuscript; available in PMC 2014 Mar 13.
Published in final edited form as: Biochem J. 2013 Jun 15; 452(3): 411–421. doi: 10.1042/BJ20121004
PMCID:
PMC3952494
AbstractArticlePDF–1.2M
13.
Disrupting the PIKE-A/Akt interaction inhibits glioblastoma cell survival, migration, invasion and colony formation
Q Qi, K He, X Liu, C Pham, C Meyerkord, H Fu, K Ye
Oncogene. Author manuscript; available in PMC 2013 Oct 25.
Published in final edited form as: Oncogene. 2013 Feb 21; 32(8): 10.1038/onc.2012.109. Published online 2012 Mar 26. doi: 10.1038/onc.2012.109
PMCID:
PMC3808079
AbstractArticlePDF–3.0M
14.
The roles of PIKE in tumorigenesis
Qi Qi, Keqiang Ye
Acta Pharmacol Sin. 2013 Aug 5; 34(8): 991–997. Published online 2013 Jun 17. doi: 10.1038/aps.2013.71
PMCID:
PMC3733165
AbstractArticlePDF–369K
15.
Fyn Regulates Adipogenesis by Promoting PIKE-A/STAT5a Interaction
Margaret Chui Ling Tse, Xia Liu, Seran Yang, Keqiang Ye, Chi Bun Chan
Mol Cell Biol. 2013 May; 33(9): 1797–1808. doi: 10.1128/MCB.01410-12
PMCID:
PMC3624174
AbstractArticlePDF–3.5M
16.
GTP-binding Protein-like Domain of AGAP1 Is Protein Binding Site That Allosterically Regulates ArfGAP Protein Catalytic Activity
Ruibai Luo, Itoro O. Akpan, Ryo Hayashi, Marek Sramko, Valarie Barr, Yoko Shiba, Paul A. Randazzo
J Biol Chem. 2012 May 18; 287(21): 17176–17185. Published online 2012 Mar 27. doi: 10.1074/jbc.M111.334458
PMCID:
PMC3366823
AbstractArticlePDF–1.1M
17.
Frequent Heterogeneous Missense Mutations of GGAP2 in Prostate Cancer: Implications for Tumor Biology, Clonality and Mutation Analysis
Yi Cai, Jianghua Wang, Chengxi Ren, Michael Ittmann
PLoS One. 2012; 7(2): e32708. Published online 2012 Feb 28. doi: 10.1371/journal.pone.0032708
PMCID:
PMC3289671
AbstractArticlePDF–180K
18.
PIKE-mediated PI3-kinase activity is required for AMPA receptor surface expression
Chi Bun Chan, Yongjun Chen, Xia Liu, Xiaoling Tang, Chi Wai Lee, Lin Mei, Keqiang Ye
EMBO J. 2011 Oct 19; 30(20): 4274–4286. Published online 2011 Aug 16. doi: 10.1038/emboj.2011.281
PMCID:
PMC3199380
AbstractArticlePDF–2.4M
19.
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
The International Multiple Sclerosis Genetics Consortium (IMSGC), Wellcome Trust Case Control Consortium 2 (WTCCC2), Stephen Sawcer, Garrett Hellenthal, Matti Pirinen, Chris C.A. Spencer, Nikolaos A. Patsopoulos, Loukas Moutsianas, Alexander Dilthey, Zhan Su, Colin Freeman, Sarah E. Hunt, Sarah Edkins, Emma Gray, David R. Booth, Simon C. Potter, An Goris, Gavin Band, Annette Bang Oturai, Amy Strange, Janna Saarela, Céline Bellenguez, Bertrand Fontaine, Matthew Gillman, Bernhard Hemmer, Rhian Gwilliam, Frauke Zipp, Alagurevathi Jayakumar, Roland Martin, Stephen Leslie, Stanley Hawkins, Eleni Giannoulatou, Sandra D’alfonso, Hannah Blackburn, Filippo Martinelli Boneschi, Jennifer Liddle, Hanne F. Harbo, Marc L. Perez, Anne Spurkland, Matthew J Waller, Marcin P. Mycko, Michelle Ricketts, Manuel Comabella, Naomi Hammond, Ingrid Kockum, Owen T. McCann, Maria Ban, Pamela Whittaker, Anu Kemppinen, Paul Weston, Clive Hawkins, Sara Widaa, John Zajicek, Serge Dronov, Neil Robertson, Suzannah J. Bumpstead, Lisa F. Barcellos, Rathi Ravindrarajah, Roby Abraham, Lars Alfredsson, Kristin Ardlie, Cristin Aubin, Amie Baker, Katharine Baker, Sergio E. Baranzini, Laura Bergamaschi, Roberto Bergamaschi, Allan Bernstein, Achim Berthele, Mike Boggild, Jonathan P. Bradfield, David Brassat, Simon A. Broadley, Dorothea Buck, Helmut Butzkueven, Ruggero Capra, William M. Carroll, Paola Cavalla, Elisabeth G. Celius, Sabine Cepok, Rosetta Chiavacci, Françoise Clerget-Darpoux, Katleen Clysters, Giancarlo Comi, Mark Cossburn, Isabelle Cournu-Rebeix, Mathew B. Cox, Wendy Cozen, Bruce A.C. Cree, Anne H. Cross, Daniele Cusi, Mark J. Daly, Emma Davis, Paul I.W. de Bakker, Marc Debouverie, Marie Beatrice D’hooghe, Katherine Dixon, Rita Dobosi, Bénédicte Dubois, David Ellinghaus, Irina Elovaara, Federica Esposito, Claire Fontenille, Simon Foote, Andre Franke, Daniela Galimberti, Angelo Ghezzi, Joseph Glessner, Refujia Gomez, Olivier Gout, Colin Graham, Struan F.A. Grant, Franca Rosa Guerini, Hakon Hakonarson, Per Hall, Anders Hamsten, Hans-Peter Hartung, Rob N. Heard, Simon Heath, Jeremy Hobart, Muna Hoshi, Carmen Infante-Duarte, Gillian Ingram, Wendy Ingram, Talat Islam, Maja Jagodic, Michael Kabesch, Allan G. Kermode, Trevor J. Kilpatrick, Cecilia Kim, Norman Klopp, Keijo Koivisto, Malin Larsson, Mark Lathrop, Jeannette S. Lechner-Scott, Maurizio A. Leone, Virpi Leppä, Ulrika Liljedahl, Izaura Lima Bomfim, Robin R. Lincoln, Jenny Link, Jianjun Liu, Åslaug R. Lorentzen, Sara Lupoli, Fabio Macciardi, Thomas Mack, Mark Marriott, Vittorio Martinelli, Deborah Mason, Jacob L. McCauley, Frank Mentch, Inger-Lise Mero, Tania Mihalova, Xavier Montalban, John Mottershead, Kjell-Morten Myhr, Paola Naldi, William Ollier, Alison Page, Aarno Palotie, Jean Pelletier, Laura Piccio, Trevor Pickersgill, Fredrik Piehl, Susan Pobywajlo, Hong L. Quach, Patricia P. Ramsay, Mauri Reunanen, Richard Reynolds, John D. Rioux, Mariaemma Rodegher, Sabine Roesner, Justin P. Rubio, Ina-Maria Rückert, Marco Salvetti, Erika Salvi, Adam Santaniello, Catherine A. Schaefer, Stefan Schreiber, Christian Schulze, Rodney J. Scott, Finn Sellebjerg, Krzysztof W. Selmaj, David Sexton, Ling Shen, Brigid Simms-Acuna, Sheila Skidmore, Patrick M.A. Sleiman, Cathrine Smestad, Per Soelberg Sørensen, Helle Bach Søndergaard, Jim Stankovich, Richard C. Strange, Anna-Maija Sulonen, Emilie Sundqvist, Ann-Christine Syvänen, Francesca Taddeo, Bruce Taylor, Jenefer M. Blackwell, Pentti Tienari, Elvira Bramon, Ayman Tourbah, Matthew A. Brown, Ewa Tronczynska, Juan P. Casas, Niall Tubridy, Aiden Corvin, Jane Vickery, Janusz Jankowski, Pablo Villoslada, Hugh S. Markus, Kai Wang, Christopher G. Mathew, James Wason, Colin N.A. Palmer, H-Erich Wichmann, Robert Plomin, Ernest Willoughby, Anna Rautanen, Juliane Winkelmann, Michael Wittig, Richard C. Trembath, Jacqueline Yaouanq, Ananth C. Viswanathan, Haitao Zhang, Nicholas W. Wood, Rebecca Zuvich, Panos Deloukas, Cordelia Langford, Audrey Duncanson, Jorge R. Oksenberg, Margaret A. Pericak-Vance, Jonathan L. Haines, Tomas Olsson, Jan Hillert, Adrian J. Ivinson, Philip L. De Jager, Leena Peltonen, Graeme J. Stewart, David A. Hafler, Stephen L. Hauser, Gil McVean, Peter Donnelly, Alastair Compston
Nature. Author manuscript; available in PMC 2012 Feb 11.
Published in final edited form as: Nature. 2011 Aug 10; 476(7359): 214–219. Published online 2011 Aug 10. doi: 10.1038/nature10251
PMCID:
PMC3182531
AbstractArticlePDF–2.0M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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